EP0975610A4 - PHARMACEUTICAL COMPOUNDS BASED ON TRIPEPTIDES AND TETRAPEPTIDES - Google Patents

PHARMACEUTICAL COMPOUNDS BASED ON TRIPEPTIDES AND TETRAPEPTIDES

Info

Publication number
EP0975610A4
EP0975610A4 EP98907625A EP98907625A EP0975610A4 EP 0975610 A4 EP0975610 A4 EP 0975610A4 EP 98907625 A EP98907625 A EP 98907625A EP 98907625 A EP98907625 A EP 98907625A EP 0975610 A4 EP0975610 A4 EP 0975610A4
Authority
EP
European Patent Office
Prior art keywords
tetrapeptides
tripeptides
pharmaceutical compounds
compounds based
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98907625A
Other languages
German (de)
French (fr)
Other versions
EP0975610A1 (en
Inventor
Bryan H Norman
Chuan Shih
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hawaii at Manoa
Wayne State University
Eli Lilly and Co
University of Hawaii at Hilo
Original Assignee
University of Hawaii at Manoa
Wayne State University
Eli Lilly and Co
University of Hawaii at Hilo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hawaii at Manoa, Wayne State University, Eli Lilly and Co, University of Hawaii at Hilo filed Critical University of Hawaii at Manoa
Publication of EP0975610A1 publication Critical patent/EP0975610A1/en
Publication of EP0975610A4 publication Critical patent/EP0975610A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EP98907625A 1997-02-26 1998-02-25 PHARMACEUTICAL COMPOUNDS BASED ON TRIPEPTIDES AND TETRAPEPTIDES Withdrawn EP0975610A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3911597P 1997-02-26 1997-02-26
US39115P 1997-02-26
PCT/US1998/003666 WO1998038178A1 (en) 1997-02-26 1998-02-25 Tripeptide and tetrapeptide pharmaceutical compounds

Publications (2)

Publication Number Publication Date
EP0975610A1 EP0975610A1 (en) 2000-02-02
EP0975610A4 true EP0975610A4 (en) 2000-05-17

Family

ID=21903772

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98907625A Withdrawn EP0975610A4 (en) 1997-02-26 1998-02-25 PHARMACEUTICAL COMPOUNDS BASED ON TRIPEPTIDES AND TETRAPEPTIDES

Country Status (5)

Country Link
EP (1) EP0975610A4 (en)
JP (1) JP2001513775A (en)
AU (1) AU6338698A (en)
CA (1) CA2281107A1 (en)
WO (1) WO1998038178A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977387A (en) * 1996-08-30 1999-11-02 Eli Lilly And Company Process for preparing pharmaceutical compounds
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996040184A1 (en) * 1995-03-07 1996-12-19 University Of Hawaii New cryptophycins from synthesis
WO1997007798A1 (en) * 1995-08-30 1997-03-06 Eli Lilly And Company Pharmaceutical compounds
WO1997023211A1 (en) * 1995-12-22 1997-07-03 Eli Lilly And Company Pharmaceutical compounds
WO1998008506A1 (en) * 1996-08-30 1998-03-05 Eli Lilly And Company Pharmaceutical compounds
WO1998008505A1 (en) * 1996-08-30 1998-03-05 Eli Lilly And Company Pharmaceutical compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194605A (en) * 1989-12-08 1993-03-16 Merck & Co., Inc. Cyclic renin inhibitors containing 2-substituted (3S,4S)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3S,4S)-5-cyclohexyl-3,4-di-hydroxy pentanoic acid or 2-substituted (4S,5S)-5-amino-6-cyclohexyl-4-hydroxyhexanoic acid or its analogs
US5254682A (en) * 1989-12-08 1993-10-19 Merck & Co., Inc. Cyclic renin inhibitors containing 3(S)-amino-4-cyclohexyl-2(R)-hydroxy-butanoic acid or 4-cyclo-hexyl-(2R, 3S)-dihydroxybutanoic acid or related analogs
US5225528A (en) * 1990-02-27 1993-07-06 Merck & Co., Inc. Cyclic hexapeptide oxytocin antagonists

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996040184A1 (en) * 1995-03-07 1996-12-19 University Of Hawaii New cryptophycins from synthesis
WO1997007798A1 (en) * 1995-08-30 1997-03-06 Eli Lilly And Company Pharmaceutical compounds
WO1997023211A1 (en) * 1995-12-22 1997-07-03 Eli Lilly And Company Pharmaceutical compounds
WO1998008506A1 (en) * 1996-08-30 1998-03-05 Eli Lilly And Company Pharmaceutical compounds
WO1998008505A1 (en) * 1996-08-30 1998-03-05 Eli Lilly And Company Pharmaceutical compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KOISO, YUKIKO ET AL: "Effects of arenastatin A and its synthetic analogs on microtubule assembly", CHEM.-BIOL. INTERACT. (1996), 102(3), 183-191, 1996, XP000872569 *
See also references of WO9838178A1 *

Also Published As

Publication number Publication date
JP2001513775A (en) 2001-09-04
CA2281107A1 (en) 1998-09-03
WO1998038178A1 (en) 1998-09-03
EP0975610A1 (en) 2000-02-02
AU6338698A (en) 1998-09-18

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