EP0977590A4 - HUMAN MONOCLONAL ANTIBODIES - Google Patents

HUMAN MONOCLONAL ANTIBODIES

Info

Publication number
EP0977590A4
EP0977590A4 EP97913749A EP97913749A EP0977590A4 EP 0977590 A4 EP0977590 A4 EP 0977590A4 EP 97913749 A EP97913749 A EP 97913749A EP 97913749 A EP97913749 A EP 97913749A EP 0977590 A4 EP0977590 A4 EP 0977590A4
Authority
EP
European Patent Office
Prior art keywords
monoclonal antibodies
human monoclonal
human
antibodies
monoclonal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97913749A
Other languages
German (de)
French (fr)
Other versions
EP0977590A1 (en
Inventor
Keith Charles Deen
Susan Beth Dillon
Terence Graham Porter
Raymond Whitney Sweet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0977590A1 publication Critical patent/EP0977590A1/en
Publication of EP0977590A4 publication Critical patent/EP0977590A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10RNA viruses
    • C07K16/11Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP97913749A 1996-11-01 1997-10-23 HUMAN MONOCLONAL ANTIBODIES Withdrawn EP0977590A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3014996P 1996-11-01 1996-11-01
US30149P 1996-11-01
PCT/US1997/019203 WO1998019704A1 (en) 1996-11-01 1997-10-23 Human monoclonal antibodies

Publications (2)

Publication Number Publication Date
EP0977590A1 EP0977590A1 (en) 2000-02-09
EP0977590A4 true EP0977590A4 (en) 2001-03-14

Family

ID=21852781

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97913749A Withdrawn EP0977590A4 (en) 1996-11-01 1997-10-23 HUMAN MONOCLONAL ANTIBODIES

Country Status (4)

Country Link
EP (1) EP0977590A4 (en)
JP (1) JP2001510329A (en)
CA (1) CA2270288A1 (en)
WO (1) WO1998019704A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030019A1 (en) * 1999-05-18 2003-08-13 Smithkline Beecham Corp HUMAN MONOCLONAL ANTIBODIES AND FUNCTIONAL FRAGMENTS OF THE SAME, A PROCEDURE FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM, A NUCLEIC ACID ISOLATED MOLECULA, A RECOMBINANT PLASMIDE, A HOSPED DIFFERENT USE OF A MUSCLE
US20020004046A1 (en) * 2000-05-03 2002-01-10 Johnson Leslie S. Combination therapy of respiratory diseases using antibodies
JP2005522996A (en) * 2001-11-02 2005-08-04 セントカー・インコーポレーテツド RSV proteins, antibodies, compositions, methods and uses
GB0210121D0 (en) 2002-05-02 2002-06-12 Celltech R&D Ltd Biological products
US7070786B2 (en) 2003-06-06 2006-07-04 Centocor, Inc. RSV proteins, antibodies, compositions, methods and uses
LT2285408T (en) 2008-06-05 2019-01-25 Ablynx N.V. Amino acid sequences directed against envelope proteins of a virus and polypeptides comprising the same for the treatment of viral diseases
JP5575377B2 (en) 2008-07-18 2014-08-20 シスメックス株式会社 RS virus detection kit and immunochromatography test device using anti-RS virus monoclonal antibody, and novel anti-RS virus monoclonal antibody
PT2438087T (en) 2009-06-05 2017-08-04 Ablynx Nv HUMAN RESPIRATORY SYNCHRONOUS (HRSV) TRIVALENT NANOBODY CONSTRUCTIONS FOR THE PREVENTION AND / OR TREATMENT OF RESPIRATORY TRACT INFECTIONS
WO2011064382A1 (en) 2009-11-30 2011-06-03 Ablynx N.V. Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
JO3555B1 (en) 2015-10-29 2020-07-05 Merck Sharp & Dohme An antibody that inactivates the human pneumonia virus

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994006448A1 (en) * 1992-09-16 1994-03-31 The Scripps Research Institute Human neutralizing monoclonal antibodies to respiratory syncytial virus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994006448A1 (en) * 1992-09-16 1994-03-31 The Scripps Research Institute Human neutralizing monoclonal antibodies to respiratory syncytial virus

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9819704A1 *
WYDE P R ET AL: "Evaluation of the protective efficacy of reshaped human monoclonal antibody RSHZ19 against respiratory syncytial virus in cotton rats.", PEDIATRIC RESEARCH, (1995 OCT) 38 (4) 543-50., XP000972993 *

Also Published As

Publication number Publication date
WO1998019704A1 (en) 1998-05-14
CA2270288A1 (en) 1998-05-14
JP2001510329A (en) 2001-07-31
EP0977590A1 (en) 2000-02-09

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