EP1030651A4 - NEW ORAL ADMINISTRATIVE FOR CARVEDILOL - Google Patents

NEW ORAL ADMINISTRATIVE FOR CARVEDILOL

Info

Publication number: EP1030651A4
Authority: EP; European Patent Office
Prior art keywords: carvedilol; new oral; oral administrative; administrative; new
Prior art date: 1997-11-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP98958546A

Other languages

German (de)

French (fr)

Other versions

EP1030651A1 (en

Inventor

Choon K Oh

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Roche Diagnostics Corp

Original Assignee

Boehringer Mannheim Pharmaceuticals Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-12

Filing date

1998-11-12

Publication date

2006-05-31

1998-11-12 Application filed by Boehringer Mannheim Pharmaceuticals Corp filed Critical Boehringer Mannheim Pharmaceuticals Corp

2000-08-30 Publication of EP1030651A1 publication Critical patent/EP1030651A1/en

2006-05-31 Publication of EP1030651A4 publication Critical patent/EP1030651A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Dispersion Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Indole Compounds (AREA)

EP98958546A 1997-11-12 1998-11-12 NEW ORAL ADMINISTRATIVE FOR CARVEDILOL Withdrawn EP1030651A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US6545697P	1997-11-12	1997-11-12
US65456P		1997-11-12
PCT/US1998/024102 WO1999024017A1 (en)	1997-11-12	1998-11-12	Novel oral dosage form for carvedilol

Publications (2)

Publication Number	Publication Date
EP1030651A1 EP1030651A1 (en)	2000-08-30
EP1030651A4 true EP1030651A4 (en)	2006-05-31

Family

ID=22062830

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP98958546A Withdrawn EP1030651A4 (en)	1997-11-12	1998-11-12	NEW ORAL ADMINISTRATIVE FOR CARVEDILOL

Country Status (14)

Country	Link
EP (1)	EP1030651A4 (en)
JP (1)	JP2001522794A (en)
KR (1)	KR20010031952A (en)
CN (1)	CN1285738A (en)
AU (1)	AU751117B2 (en)
BR (1)	BR9814127A (en)
CA (1)	CA2309542A1 (en)
HU (1)	HUP0004345A3 (en)
IL (1)	IL136028A0 (en)
NO (1)	NO20002439L (en)
NZ (1)	NZ504418A (en)
PL (1)	PL340456A1 (en)
TR (1)	TR200001362T2 (en)
WO (1)	WO1999024017A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003275953A1 (en)	2002-11-08	2004-06-07	Egalet A/S	Controlled release carvedilol compositions
WO2004056336A2 (en) *	2002-12-20	2004-07-08	Ranbaxy Laboratories Limited	Controlled release, multiple unit drug delivery systems
US8734850B2 (en) *	2003-11-25	2014-05-27	Flamel Technologies	Oral medicinal product with modified release of at least one active principle in multimicrocapsular form
JP2007512350A (en) *	2003-11-25	2007-05-17	エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド	Carvedilol composition treatment and delivery methods
US20190083399A9 (en) *	2006-04-03	2019-03-21	Isa Odidi	Drug delivery composition
TWI415604B (en) *	2009-09-29	2013-11-21	Tsh Biopharm Corp Ltd	Regulated release of caffetilol dosage form
JP5714562B2 (en) *	2010-02-22	2015-05-07	第一三共株式会社	Oral sustained-release solid preparation
ES2706880T3 (en)	2010-02-22	2019-04-01	Daiichi Sankyo Co Ltd	Sustained-release solid preparation for oral use
JP5870023B2 (en) *	2010-02-22	2016-02-24	第一三共株式会社	Oral sustained-release solid preparation
CA2883077C (en)	2012-09-03	2017-03-07	Daiichi Sankyo Company, Limited	Hydromorphone hydrochloride-containing oral sustained-release pharmaceutical composition
KR102158339B1 (en) *	2016-02-05	2020-09-21	삼진제약주식회사	Carvedilol immediate release formulation having improved madescent
KR102492147B1 (en)	2020-12-30	2023-01-26	단국대학교 천안캠퍼스 산학협력단	Carvedilol loaded solid oral compositions using self-nanoemulsifying drug delivery system and methods for their preparation
KR102525298B1 (en)	2020-12-30	2023-04-25	단국대학교 천안캠퍼스 산학협력단	Carvedilol loaded solid dispersion with increased oral bioavailability and methods for their preparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998010754A1 (en) *	1996-09-12	1998-03-19	Roche Diagnostics Gmbh	Fast decomposing pellets
US5760069A (en) *	1995-02-08	1998-06-02	Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1	Method of treatment for decreasing mortality resulting from congestive heart failure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2815926A1 (en) *	1978-04-13	1979-10-18	Boehringer Mannheim Gmbh	NEW CARBAZOLYL- (4) -OXY-PROPANOLAMINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
JPS5598120A (en) *	1979-01-16	1980-07-25	Shin Etsu Chem Co Ltd	Preparation of drug having enteric coating
CA1146866A (en) *	1979-07-05	1983-05-24	Yamanouchi Pharmaceutical Co. Ltd.	Process for the production of sustained release pharmaceutical composition of solid medical material
US4680323A (en) *	1983-12-01	1987-07-14	Hans Lowey	Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
ATE134300T1 (en) *	1990-10-23	1996-03-15	Davband Pty Ltd	BACK SUPPORT FOR A CHAIR OR SEAT

1998
- 1998-11-12 EP EP98958546A patent/EP1030651A4/en not_active Withdrawn
- 1998-11-12 KR KR1020007005059A patent/KR20010031952A/en not_active Ceased
- 1998-11-12 PL PL98340456A patent/PL340456A1/en unknown
- 1998-11-12 IL IL13602898A patent/IL136028A0/en not_active IP Right Cessation
- 1998-11-12 CN CN98813082A patent/CN1285738A/en active Pending
- 1998-11-12 HU HU0004345A patent/HUP0004345A3/en unknown
- 1998-11-12 BR BR9814127-9A patent/BR9814127A/en not_active IP Right Cessation
- 1998-11-12 AU AU14569/99A patent/AU751117B2/en not_active Ceased
- 1998-11-12 WO PCT/US1998/024102 patent/WO1999024017A1/en not_active Ceased
- 1998-11-12 TR TR2000/01362T patent/TR200001362T2/en unknown
- 1998-11-12 JP JP2000520110A patent/JP2001522794A/en active Pending
- 1998-11-12 NZ NZ504418A patent/NZ504418A/en unknown
- 1998-11-12 CA CA002309542A patent/CA2309542A1/en not_active Abandoned
2000
- 2000-05-11 NO NO20002439A patent/NO20002439L/en unknown

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5760069A (en) *	1995-02-08	1998-06-02	Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1	Method of treatment for decreasing mortality resulting from congestive heart failure
WO1998010754A1 (en) *	1996-09-12	1998-03-19	Roche Diagnostics Gmbh	Fast decomposing pellets

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ROTE LISTE SERVICE GMBH: "Rote Liste 1997", 1997, ECV - EDITIO CANTOR, AULENDORF, GERMANY, XP002352847 *
See also references of WO9924017A1 *

Also Published As

Publication number	Publication date
HUP0004345A2 (en)	2001-06-28
BR9814127A (en)	2000-10-03
CN1285738A (en)	2001-02-28
NO20002439D0 (en)	2000-05-11
TR200001362T2 (en)	2000-09-21
CA2309542A1 (en)	1999-05-20
AU1456999A (en)	1999-05-31
NO20002439L (en)	2000-05-11
JP2001522794A (en)	2001-11-20
NZ504418A (en)	2003-02-28
AU751117B2 (en)	2002-08-08
KR20010031952A (en)	2001-04-16
HUP0004345A3 (en)	2001-10-29
PL340456A1 (en)	2001-02-12
IL136028A0 (en)	2001-05-20
EP1030651A1 (en)	2000-08-30
WO1999024017A1 (en)	1999-05-20

Legal Events

Date	Code	Title	Description
2000-07-14	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2000-08-30	17P	Request for examination filed	Effective date: 20000515
2000-08-30	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2000-08-30	AX	Request for extension of the european patent	Free format text: SI PAYMENT 20000515
2006-05-31	A4	Supplementary search report drawn up and despatched	Effective date: 20060419
2006-11-22	17Q	First examination report despatched	Effective date: 20061020
2007-09-14	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2007-10-17	18D	Application deemed to be withdrawn	Effective date: 20070301

Publication	Publication Date	Title
DE69830413D1 (en)	2005-07-07	DEVICE FOR DENTAL IMPRESSIONS
ID20233A (en)	1998-10-29	ORAL COMPOSITION
DE69912286D1 (en)	2003-11-27	TOOTHBRUSH
DE69827672D1 (en)	2004-12-23	TELESCOPIC-LIKE INTRAORAL ELEMENT
DE69838498D1 (en)	2007-11-15	Configuration procedure for network device
DE69810911D1 (en)	2003-02-27	TOOTHBRUSH
DE69929778D1 (en)	2006-04-20	RING HOLDER FOR ANULOPLASTICS
DE69800298D1 (en)	2000-10-19	Connection configuration for stator
DE69840916D1 (en)	2009-07-30	METER
ID27002A (en)	2001-02-22	CASASAGE OBSERVERS
ID26720A (en)	2001-02-01	ORAL COMPOSITION
DE69934771D1 (en)	2007-02-22	TOOTHBRUSH
DK1051179T3 (en)	2005-10-31	Anti-estrogen plus progestin-containing oral contraceptives
IT240061Y1 (en)	2001-03-26	ADAPTER
DE59806063D1 (en)	2002-11-28	TOOTHBRUSH
DE59804601D1 (en)	2002-08-01	METER
ATA216897A (en)	1998-11-15	APPLICATOR RING FOR CONDOMS
ID29128A (en)	2001-08-02	GEN FOR EPOTILON BIOSINTHESIS
DE59800735D1 (en)	2001-06-21	INTERCHANGEABLE GEARBOX
EP1030651A4 (en)	2006-05-31	NEW ORAL ADMINISTRATIVE FOR CARVEDILOL
DK1023035T3 (en)	2002-09-16	The oral composition
DE59907008D1 (en)	2003-10-23	inking
ID20466A (en)	1998-12-24	ORAL COMPOSITION
DE69810090D1 (en)	2003-01-23	REMOVER FOR CERATOUS COMEDON
FR2782671B3 (en)	2000-07-21	DELIVERED