EP1058500A4 - GENE HELIOS - Google Patents

GENE HELIOS

Info

Publication number
EP1058500A4
EP1058500A4 EP99909641A EP99909641A EP1058500A4 EP 1058500 A4 EP1058500 A4 EP 1058500A4 EP 99909641 A EP99909641 A EP 99909641A EP 99909641 A EP99909641 A EP 99909641A EP 1058500 A4 EP1058500 A4 EP 1058500A4
Authority
EP
European Patent Office
Prior art keywords
helios
gene
gene helios
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99909641A
Other languages
German (de)
French (fr)
Other versions
EP1058500A1 (en
Inventor
Katia Georgopoulos
Bruce A Morgan
Clair Kelley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of EP1058500A1 publication Critical patent/EP1058500A1/en
Publication of EP1058500A4 publication Critical patent/EP1058500A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP99909641A 1998-02-27 1999-02-26 GENE HELIOS Withdrawn EP1058500A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7632598P 1998-02-27 1998-02-27
US76325P 1998-02-27
PCT/US1999/004224 WO1999043208A1 (en) 1998-02-27 1999-02-26 The helios gene

Publications (2)

Publication Number Publication Date
EP1058500A1 EP1058500A1 (en) 2000-12-13
EP1058500A4 true EP1058500A4 (en) 2002-05-08

Family

ID=22131293

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99909641A Withdrawn EP1058500A4 (en) 1998-02-27 1999-02-26 GENE HELIOS

Country Status (3)

Country Link
EP (1) EP1058500A4 (en)
JP (1) JP2002504357A (en)
WO (1) WO1999043208A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10066207B2 (en) 2012-04-18 2018-09-04 Board Of Trustees Of Michigan State University Natural killer cells with enhanced immune response
CN110546265A (en) * 2017-02-09 2019-12-06 因达普塔治疗公司 Engineered natural killer (NK) cells and compositions and methods thereof
US12410402B2 (en) 2018-11-21 2025-09-09 Indapta Therapeutics, Inc. Methods for expansion of natural killer (NK) cell subset and related compositions and methods

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004372A1 (en) * 1994-07-29 1996-02-15 The General Hospital Corporation Ikaros transgenic cells and animals

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004372A1 (en) * 1994-07-29 1996-02-15 The General Hospital Corporation Ikaros transgenic cells and animals

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL_OV EMBL; 29 October 1997 (1997-10-29), TURPEN ET AL.: "Xenopus laevis ikaros-related transcription factor", XP002189272 *
DATABASE SWISSPROT Swissprot; 1 January 1998 (1998-01-01), TURPEN J. ET AL.: "Ikaros-related transcription factor (fragment)", XP002189273 *
HANSEN JOHN D ET AL: "Conservation of a master hematopoietic switch gene during vertebrate evolution: Isolation and characterization of Ikaros and teleost and amphibian species.", EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 27, no. 11, November 1997 (1997-11-01), pages 3049 - 3058, XP001056033, ISSN: 0014-2980 *
MOLNAR ARPAD ET AL: "The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse.", JOURNAL OF IMMUNOLOGY, vol. 156, no. 2, 1996, pages 585 - 592, XP001055887, ISSN: 0022-1767 *
NIETFELD WILFRIED ET AL: "Cloning and sequencing of hIk-1, a cDNA encoding a human homologue of mouse Ikaros/LyF-1.", IMMUNOLOGY LETTERS, vol. 49, no. 1-2, 1996, pages 139 - 141, XP002189271, ISSN: 0165-2478 *
See also references of WO9943208A1 *

Also Published As

Publication number Publication date
WO1999043208A1 (en) 1999-09-02
JP2002504357A (en) 2002-02-12
EP1058500A1 (en) 2000-12-13

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Legal Events

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Inventor name: KELLEY, CLAIR

Inventor name: MORGAN, BRUCE, A.

Inventor name: GEORGOPOULOS, KATIA

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