EP1079967A4 - Liquid labeling with fluorescent microparticles - Google Patents

Liquid labeling with fluorescent microparticles

Info

Publication number
EP1079967A4
EP1079967A4 EP99917429A EP99917429A EP1079967A4 EP 1079967 A4 EP1079967 A4 EP 1079967A4 EP 99917429 A EP99917429 A EP 99917429A EP 99917429 A EP99917429 A EP 99917429A EP 1079967 A4 EP1079967 A4 EP 1079967A4
Authority
EP
European Patent Office
Prior art keywords
fluorescent microparticles
liquid labeling
labeling
liquid
microparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99917429A
Other languages
German (de)
French (fr)
Other versions
EP1079967A1 (en
Inventor
Van S Chandler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luminex Corp
Original Assignee
Luminex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luminex Corp filed Critical Luminex Corp
Publication of EP1079967A1 publication Critical patent/EP1079967A1/en
Publication of EP1079967A4 publication Critical patent/EP1079967A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06KGRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K19/00Record carriers for use with machines and with at least a part designed to carry digital markings
    • G06K19/06Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
    • G06K19/06009Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code with optically detectable marking
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06KGRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K19/00Record carriers for use with machines and with at least a part designed to carry digital markings
    • G06K19/06Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
    • G06K2019/06215Aspects not covered by other subgroups
    • G06K2019/06234Aspects not covered by other subgroups miniature-code

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP99917429A 1998-04-13 1999-04-13 Liquid labeling with fluorescent microparticles Withdrawn EP1079967A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8148798P 1998-04-13 1998-04-13
US81487P 1998-04-13
PCT/US1999/007993 WO1999052708A1 (en) 1998-04-13 1999-04-13 Liquid labeling with fluorescent microparticles

Publications (2)

Publication Number Publication Date
EP1079967A1 EP1079967A1 (en) 2001-03-07
EP1079967A4 true EP1079967A4 (en) 2003-07-23

Family

ID=22164502

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99917429A Withdrawn EP1079967A4 (en) 1998-04-13 1999-04-13 Liquid labeling with fluorescent microparticles

Country Status (3)

Country Link
EP (1) EP1079967A4 (en)
AU (1) AU3555599A (en)
WO (1) WO1999052708A1 (en)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696304B1 (en) 1999-02-24 2004-02-24 Luminex Corporation Particulate solid phase immobilized protein quantitation
US6759235B2 (en) 2000-04-06 2004-07-06 Quantum Dot Corporation Two-dimensional spectral imaging system
FR2812300B1 (en) * 2000-07-28 2003-01-10 Cypher Science SECURE OPTICALLY REVELABLE LIQUID INK AND METHOD OF MARKING PRODUCTS WITH SUCH AN INK
US7465540B2 (en) 2000-09-21 2008-12-16 Luminex Corporation Multiple reporter read-out for bioassays
US20020142345A1 (en) * 2000-12-22 2002-10-03 Nelsen Anita J. Methods for encoding and decoding complex mixtures in arrayed assays
US7473767B2 (en) 2001-07-03 2009-01-06 The Institute For Systems Biology Methods for detection and quantification of analytes in complex mixtures
AU2002362013B2 (en) 2001-11-21 2008-04-24 Applied Biosystems, Llc. Digital assay
EP1365034A3 (en) 2002-05-21 2004-02-18 Bayer HealthCare AG Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia
GB0222728D0 (en) * 2002-10-01 2002-11-06 Shell Int Research System for identifying lubricating oils
US7312257B2 (en) 2003-01-23 2007-12-25 General Electric Company Polymer encapsulation of high aspect ratio materials and methods of making same
US7323696B2 (en) 2004-01-09 2008-01-29 Applera Corporation Phosphor particle coded beads
US20050277710A1 (en) * 2004-06-14 2005-12-15 Joyce Richard P Tagged resin, method of making a tagged resin, and articles made therefrom
WO2006044413A2 (en) * 2004-10-12 2006-04-27 Luminex Corporation Methods for forming dyed microspheres and populations of dyed microspheres
US7470731B2 (en) * 2005-06-24 2008-12-30 Pitney Bowes Inc. Fluorescent ink
DE102005062027A1 (en) 2005-12-22 2007-06-28 Basf Ag Aqueous dispersions of polymers containing a fluorescent dye, process for their preparation and their use for marking materials
EP1963531B1 (en) 2005-12-23 2011-09-21 Nanostring Technologies, Inc. Nanoreporters and methods of manufacturing and use thereof
WO2008109176A2 (en) 2007-03-07 2008-09-12 President And Fellows Of Harvard College Assays and other reactions involving droplets
JP5738597B2 (en) 2007-12-21 2015-06-24 プレジデント アンド フェローズ オブ ハーバード カレッジ Systems and methods for nucleic acid sequencing
GB0725153D0 (en) * 2007-12-21 2008-01-30 Medinnova As Protein analysis
US20110218123A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Creation of libraries of droplets and related species
WO2010080134A1 (en) 2008-12-19 2010-07-15 President And Fellows Of Harvard College Particle-assisted nucleic acid sequencing
CN102648053B (en) 2009-10-27 2016-04-27 哈佛学院院长等 Drop formation technology
WO2011073354A1 (en) 2009-12-18 2011-06-23 Construction Research & Technology Gmbh Method for qualitatively and quantitatively identifying bulk goods
EP4361609A3 (en) 2012-02-03 2024-07-17 California Institute of Technology Signal encoding and decoding in multiplexed biochemical assays
CN104662172B (en) 2012-08-03 2018-07-06 加州理工学院 Multiplexing and quantification in PCR with reduced hardware and requirements
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
CA3216609C (en) 2012-08-14 2024-05-14 10X Genomics, Inc. Microcapsule compositions and methods
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10584381B2 (en) 2012-08-14 2020-03-10 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
WO2014093676A1 (en) 2012-12-14 2014-06-19 10X Technologies, Inc. Methods and systems for processing polynucleotides
AU2014214682B2 (en) 2013-02-08 2018-07-26 10X Genomics, Inc. Polynucleotide barcode generation
US10395758B2 (en) 2013-08-30 2019-08-27 10X Genomics, Inc. Sequencing methods
EP3065712A4 (en) 2013-11-08 2017-06-21 President and Fellows of Harvard College Microparticles, methods for their preparation and use
FR3013846A1 (en) 2013-11-22 2015-05-29 Jacques Degroote CHEMICAL MARKING METHOD OF LOTS OF CARBON DIOXIDE TO ENSURE TRACEABILITY
US9824068B2 (en) 2013-12-16 2017-11-21 10X Genomics, Inc. Methods and apparatus for sorting data
WO2015157567A1 (en) 2014-04-10 2015-10-15 10X Genomics, Inc. Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same
MX2016016904A (en) 2014-06-26 2017-03-27 10X Genomics Inc NUCLEIC ACID SEQUENCE ANALYSIS.
US12312640B2 (en) 2014-06-26 2025-05-27 10X Genomics, Inc. Analysis of nucleic acid sequences
JP2017526046A (en) 2014-06-26 2017-09-07 10エックス ゲノミクス,インコーポレイテッド Nucleic acid sequence assembly process and system
CN113249435B (en) 2014-06-26 2024-09-03 10X基因组学有限公司 Method for analyzing nucleic acid from single cell or cell population
MX2017005267A (en) 2014-10-29 2017-07-26 10X Genomics Inc Methods and compositions for targeted nucleic acid sequencing.
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
SG11201705615UA (en) 2015-01-12 2017-08-30 10X Genomics Inc Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
EP3245605B1 (en) 2015-01-13 2022-04-20 10X Genomics, Inc. Systems and methods for visualizing structural variation and phasing information
WO2016130578A1 (en) 2015-02-09 2016-08-18 10X Genomics, Inc. Systems and methods for determining structural variation and phasing using variant call data
EP4286516A3 (en) 2015-02-24 2024-03-06 10X Genomics, Inc. Partition processing methods and systems
BR112017018054A2 (en) 2015-02-24 2018-07-24 10X Genomics Inc Methods for Covering Targeted Nucleic Acid Sequences
US20160371704A1 (en) * 2015-06-18 2016-12-22 Kuantag Nanoteknolojiler Gelistirme Ve Uretim A.S. Integrated fuel tracking system
CA3001679A1 (en) 2015-10-13 2017-04-20 President And Fellows Of Harvard College Systems and methods for making and using gel microspheres
US11371094B2 (en) 2015-11-19 2022-06-28 10X Genomics, Inc. Systems and methods for nucleic acid processing using degenerate nucleotides
SG11201804086VA (en) 2015-12-04 2018-06-28 10X Genomics Inc Methods and compositions for nucleic acid analysis
JP6735348B2 (en) 2016-02-11 2020-08-05 10エックス ジェノミクス, インコーポレイテッド Systems, methods and media for de novo assembly of whole genome sequence data
WO2017197343A2 (en) 2016-05-12 2017-11-16 10X Genomics, Inc. Microfluidic on-chip filters
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
WO2017218777A1 (en) 2016-06-17 2017-12-21 California Institute Of Technology Nucleic acid reactions and related methods and compositions
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US12264411B2 (en) 2017-01-30 2025-04-01 10X Genomics, Inc. Methods and systems for analysis
CN110214186B (en) 2017-01-30 2023-11-24 10X基因组学有限公司 Methods and systems for droplet-based single cell barcoding
US10995333B2 (en) 2017-02-06 2021-05-04 10X Genomics, Inc. Systems and methods for nucleic acid preparation
EP3625715A4 (en) 2017-05-19 2021-03-17 10X Genomics, Inc. SYSTEMS AND PROCEDURES FOR THE ANALYSIS OF DATA SETS
CN109526228B (en) 2017-05-26 2022-11-25 10X基因组学有限公司 Single cell analysis of transposase accessible chromatin
US10844372B2 (en) 2017-05-26 2020-11-24 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
US10590244B2 (en) 2017-10-04 2020-03-17 10X Genomics, Inc. Compositions, methods, and systems for bead formation using improved polymers
US10837047B2 (en) 2017-10-04 2020-11-17 10X Genomics, Inc. Compositions, methods, and systems for bead formation using improved polymers
WO2019084043A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. Methods and systems for nuclecic acid preparation and chromatin analysis
CN114525273B (en) 2017-10-27 2025-01-28 10X基因组学有限公司 Methods and systems for sample preparation and analysis
EP3954782A1 (en) 2017-11-15 2022-02-16 10X Genomics, Inc. Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
WO2019108851A1 (en) 2017-11-30 2019-06-06 10X Genomics, Inc. Systems and methods for nucleic acid preparation and analysis
CN118818037A (en) 2017-12-12 2024-10-22 10X基因组学有限公司 Systems and methods for single cell processing
CN118547046A (en) 2017-12-22 2024-08-27 10X基因组学有限公司 Systems and methods for processing nucleic acid molecules from one or more cells
WO2019157529A1 (en) 2018-02-12 2019-08-15 10X Genomics, Inc. Methods characterizing multiple analytes from individual cells or cell populations
US11639928B2 (en) 2018-02-22 2023-05-02 10X Genomics, Inc. Methods and systems for characterizing analytes from individual cells or cell populations
WO2019169028A1 (en) 2018-02-28 2019-09-06 10X Genomics, Inc. Transcriptome sequencing through random ligation
CN112262218B (en) 2018-04-06 2024-11-08 10X基因组学有限公司 Systems and methods for quality control in single cell processing
CN112424377A (en) 2018-04-17 2021-02-26 克罗玛科德公司 Method and system for multiplex analysis
WO2019217758A1 (en) 2018-05-10 2019-11-14 10X Genomics, Inc. Methods and systems for molecular library generation
US11932899B2 (en) 2018-06-07 2024-03-19 10X Genomics, Inc. Methods and systems for characterizing nucleic acid molecules
US11703427B2 (en) 2018-06-25 2023-07-18 10X Genomics, Inc. Methods and systems for cell and bead processing
US12203129B2 (en) 2018-07-03 2025-01-21 ChromaCode, Inc. Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays
US12188014B1 (en) 2018-07-25 2025-01-07 10X Genomics, Inc. Compositions and methods for nucleic acid processing using blocking agents
US20200032335A1 (en) 2018-07-27 2020-01-30 10X Genomics, Inc. Systems and methods for metabolome analysis
EP3830289B1 (en) 2018-08-03 2026-02-11 10X Genomics, Inc. Methods to minimize barcode exchange
WO2020041148A1 (en) 2018-08-20 2020-02-27 10X Genomics, Inc. Methods and systems for detection of protein-dna interactions using proximity ligation
US12065688B2 (en) 2018-08-20 2024-08-20 10X Genomics, Inc. Compositions and methods for cellular processing
US11459607B1 (en) 2018-12-10 2022-10-04 10X Genomics, Inc. Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes
US12169198B2 (en) 2019-01-08 2024-12-17 10X Genomics, Inc. Systems and methods for sample analysis
US11845983B1 (en) 2019-01-09 2023-12-19 10X Genomics, Inc. Methods and systems for multiplexing of droplet based assays
WO2020167866A1 (en) 2019-02-12 2020-08-20 10X Genomics, Inc. Systems and methods for transposon loading
US11851683B1 (en) 2019-02-12 2023-12-26 10X Genomics, Inc. Methods and systems for selective analysis of cellular samples
US11467153B2 (en) 2019-02-12 2022-10-11 10X Genomics, Inc. Methods for processing nucleic acid molecules
US12275993B2 (en) 2019-02-12 2025-04-15 10X Genomics, Inc. Analysis of nucleic acid sequences
WO2020167862A1 (en) 2019-02-12 2020-08-20 10X Genomics, Inc. Systems and methods for transfer of reagents between droplets
SG11202108788TA (en) 2019-02-12 2021-09-29 10X Genomics Inc Methods for processing nucleic acid molecules
US12305239B2 (en) 2019-02-12 2025-05-20 10X Genomics, Inc. Analysis of nucleic acid sequences
US11655499B1 (en) 2019-02-25 2023-05-23 10X Genomics, Inc. Detection of sequence elements in nucleic acid molecules
CN113767178A (en) 2019-03-11 2021-12-07 10X基因组学有限公司 Systems and methods for processing optically labeled beads
CN113811619A (en) 2019-03-27 2021-12-17 10X基因组学有限公司 Systems and methods for processing RNA from cells
US12235262B1 (en) 2019-09-09 2025-02-25 10X Genomics, Inc. Methods and systems for single cell protein analysis
US12449419B1 (en) 2020-02-12 2025-10-21 10X Genomics, Inc. Methods for detecting binding of peptide-MHC monomers to T cells
CN115428088A (en) 2020-02-13 2022-12-02 10X基因组学有限公司 Systems and methods for joint interactive visualization of gene expression and DNA chromatin accessibility
US11851700B1 (en) 2020-05-13 2023-12-26 10X Genomics, Inc. Methods, kits, and compositions for processing extracellular molecules
US12480158B1 (en) 2020-11-05 2025-11-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US12084715B1 (en) 2020-11-05 2024-09-10 10X Genomics, Inc. Methods and systems for reducing artifactual antisense products
US12398262B1 (en) 2021-01-22 2025-08-26 10X Genomics, Inc. Triblock copolymer-based cell stabilization and fixation system and methods of use thereof
CN120158497A (en) 2021-02-23 2025-06-17 10X基因组学有限公司 Probe-based nucleic acid and protein analysis
DE102023119364A1 (en) 2023-07-21 2025-01-23 Giesecke+Devrient Currency Technology Gmbh security feature, printing ink, value document and value document system

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552812A (en) * 1981-07-01 1985-11-12 Yeda Research And Development Company Process for the production of polyacrolein microspheres and grafted microspheres
EP0230768A1 (en) * 1985-12-20 1987-08-05 Syntex (U.S.A.) Inc. Particle separation method
US5525516A (en) * 1994-09-30 1996-06-11 Eastman Chemical Company Method for tagging petroleum products
US5573909A (en) * 1992-05-13 1996-11-12 Molecular Probes, Inc. Fluorescent labeling using microparticles with controllable stokes shift
WO1997014028A2 (en) * 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
US5656750A (en) * 1991-11-20 1997-08-12 Polaroid Corporation Processes for the preparation of squarylium dyes
US5723218A (en) * 1990-04-16 1998-03-03 Molecular Probes, Inc. Dipyrrometheneboron difluoride labeled flourescent microparticles
WO1999019515A1 (en) * 1997-10-14 1999-04-22 Luminex Corporation Precision fluorescently dyed particles and methods of making and using same
WO1999037814A1 (en) * 1998-01-22 1999-07-29 Luminex Corporation Microparticles with multiple fluorescent signals

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267234A (en) 1978-03-17 1981-05-12 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US4267235A (en) 1979-03-19 1981-05-12 California Institute Of Technology Polyglutaraldehyde microspheres
US4530840A (en) 1982-07-29 1985-07-23 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
US4677138A (en) 1983-10-19 1987-06-30 Yeda Research And Development Co., Ltd. High yield process for producing polyaldehyde microspheres
US5417986A (en) 1984-03-16 1995-05-23 The United States Of America As Represented By The Secretary Of The Army Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
US4677045A (en) 1984-07-27 1987-06-30 International Business Machines Corporation Squarylium charge generating dye and electrophotographic photoconductor
US4665024A (en) 1984-10-01 1987-05-12 Becton, Dickinson And Company Fluorescent gram stain
US5102872A (en) 1985-09-20 1992-04-07 Cetus Corporation Controlled-release formulations of interleukin-2
GB8601100D0 (en) 1986-01-17 1986-02-19 Cosmas Damian Ltd Drug delivery system
EP0248531A3 (en) 1986-05-02 1988-09-28 Southern Research Institute Encapsulated nucleic acids
EP0257915B1 (en) 1986-08-11 1993-03-10 Innovata Biomed Limited Pharmaceutical formulations comprising microcapsules
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US4981625A (en) * 1988-03-14 1991-01-01 California Institute Of Technology Monodisperse, polymeric microspheres produced by irradiation of slowly thawing frozen drops
US5237498A (en) 1988-07-08 1993-08-17 Hitachi, Ltd. System and method for computing profits for individual entities of an entity group via use of means to retrieve and process data for specific entities
DK0528978T3 (en) 1990-05-16 2003-02-17 Southern Res Inst Microcapsules for regulated delivery and their use in stimulating nerve fiber growth
GB9016885D0 (en) 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
US5149543A (en) 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
US5293050A (en) 1993-03-25 1994-03-08 International Business Machines Corporation Semiconductor quantum dot light emitting/detecting devices
US5565554A (en) 1994-07-29 1996-10-15 The Regents Of The University Of California Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores
US5736330A (en) 1995-10-11 1998-04-07 Luminex Corporation Method and compositions for flow cytometric determination of DNA sequences

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552812A (en) * 1981-07-01 1985-11-12 Yeda Research And Development Company Process for the production of polyacrolein microspheres and grafted microspheres
EP0230768A1 (en) * 1985-12-20 1987-08-05 Syntex (U.S.A.) Inc. Particle separation method
US5723218A (en) * 1990-04-16 1998-03-03 Molecular Probes, Inc. Dipyrrometheneboron difluoride labeled flourescent microparticles
US5656750A (en) * 1991-11-20 1997-08-12 Polaroid Corporation Processes for the preparation of squarylium dyes
US5573909A (en) * 1992-05-13 1996-11-12 Molecular Probes, Inc. Fluorescent labeling using microparticles with controllable stokes shift
US5525516A (en) * 1994-09-30 1996-06-11 Eastman Chemical Company Method for tagging petroleum products
US5525516B1 (en) * 1994-09-30 1999-11-09 Eastman Chem Co Method for tagging petroleum products
WO1997014028A2 (en) * 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
WO1999019515A1 (en) * 1997-10-14 1999-04-22 Luminex Corporation Precision fluorescently dyed particles and methods of making and using same
WO1999037814A1 (en) * 1998-01-22 1999-07-29 Luminex Corporation Microparticles with multiple fluorescent signals

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BIOTECHNOL BIOENG;BIOTECHNOLOGY AND BIOENGINEERING MAR 5 1997 JOHN WILEY & SONS INC, NEW YORK, NY, USA, vol. 53, no. 5, 5 March 1997 (1997-03-05), pages 459 - 469 *
DATABASE COMPENDEX [online] ENGINEERING INFORMATION, INC., NEW YORK, NY, US; BHATTACHARYYA BHUPATI R ET AL: "APPLICATION OF MONODISPERSE FUNCTIONAL AND FLUORESCENT LATEX PARTICLES", XP002232532, Database accession no. EIX78040005441 *
DATABASE COMPENDEX [online] ENGINEERING INFORMATION, INC., NEW YORK, NY, US; OKABE SATOSHI ET AL: "Uptake and release of inert fluorescence particles by mixed population biofilms", XP002232531, Database accession no. EIX97223597218 *
POLYM NEWS 1977, vol. 4, no. 3, 1977, pages 107 - 114 *
SCHARF R E ET AL: "PLATELET STORAGE LESIONS: ANALYSIS OF PLATELET MEMBRANE GLYCOPROTEINS AND PLATELET-DERIVED MICROPARTICLES BY FLUORESCENCE-ACTIVATED FLOW CYTOMETRY", TRANSFUSION SCIENCE, PERGAMON PRESS, OXFORD, GB, vol. 14, no. 2, 1993, pages 189 - 194, XP000998137, ISSN: 0955-3886 *
See also references of WO9952708A1 *

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Publication number Publication date
WO1999052708A1 (en) 1999-10-21
AU3555599A (en) 1999-11-01
EP1079967A1 (en) 2001-03-07

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