EP1100523A4 - TREATMENT OF ISCHEMIA OR INJURY OF THE CENTRAL NERVOUS SYSTEM WITH EPIDERMAL GROWTH FACTOR-SIMILAR POLYPEPTIDES - Google Patents

TREATMENT OF ISCHEMIA OR INJURY OF THE CENTRAL NERVOUS SYSTEM WITH EPIDERMAL GROWTH FACTOR-SIMILAR POLYPEPTIDES

Info

Publication number
EP1100523A4
EP1100523A4 EP99939096A EP99939096A EP1100523A4 EP 1100523 A4 EP1100523 A4 EP 1100523A4 EP 99939096 A EP99939096 A EP 99939096A EP 99939096 A EP99939096 A EP 99939096A EP 1100523 A4 EP1100523 A4 EP 1100523A4
Authority
EP
European Patent Office
Prior art keywords
ischemia
injury
treatment
growth factor
nervous system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99939096A
Other languages
German (de)
French (fr)
Other versions
EP1100523A1 (en
Inventor
Seth P Finklestein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of EP1100523A1 publication Critical patent/EP1100523A1/en
Publication of EP1100523A4 publication Critical patent/EP1100523A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP99939096A 1998-08-07 1999-08-06 TREATMENT OF ISCHEMIA OR INJURY OF THE CENTRAL NERVOUS SYSTEM WITH EPIDERMAL GROWTH FACTOR-SIMILAR POLYPEPTIDES Withdrawn EP1100523A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9583098P 1998-08-07 1998-08-07
US95830P 1998-08-07
PCT/US1999/018022 WO2000007611A1 (en) 1998-08-07 1999-08-06 Treatment of central nervous system ischemia or trauma with epidermal growth factor-like polypeptides

Publications (2)

Publication Number Publication Date
EP1100523A1 EP1100523A1 (en) 2001-05-23
EP1100523A4 true EP1100523A4 (en) 2005-02-02

Family

ID=22253781

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99939096A Withdrawn EP1100523A4 (en) 1998-08-07 1999-08-06 TREATMENT OF ISCHEMIA OR INJURY OF THE CENTRAL NERVOUS SYSTEM WITH EPIDERMAL GROWTH FACTOR-SIMILAR POLYPEPTIDES

Country Status (4)

Country Link
EP (1) EP1100523A4 (en)
JP (1) JP2002522394A (en)
CA (1) CA2337964A1 (en)
WO (1) WO2000007611A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060141455A1 (en) 2002-01-08 2006-06-29 Rhonda Hansen Gene products differentially expressed in cancerous breast cells and their methods of use
EP1449538A1 (en) * 2003-02-21 2004-08-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Inhibition of TACE or amphiregulin for the modulation of EGF receptor signal transactivation
WO2015134869A2 (en) * 2014-03-06 2015-09-11 Children's National Medical Center Treatment of neonatal brain injury with hb-egf
US20240315219A1 (en) * 2021-07-07 2024-09-26 Adel, Inc. Animal model for diseases associated with absence or reduction of social dominance, and pharmaceutical composition for preventing or treating diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE199095T1 (en) * 1990-10-16 2001-02-15 Childrens Medical Center HEPARIN BINDING MITOGEN WITH HOMOLOGY TO THE EPIDERMIS GROWTH FACTOR (EGF)

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CADAY C G ET AL: "Heparin-binding epidermal growth factor, in combination with basic fibroblast growth factor, promotes glial cell process formation in primary glial cell cultures", SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 23, no. 1-2, 1997, & 27TH ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; NEW ORLEANS, LOUISIANA, USA; OCTOBER 25-30, 1997, pages 2439, XP008039950, ISSN: 0190-5295 *
HAYASE YONEKO ET AL: "Expression of heparin-binding epidermal growth factor-like growth factor in rat brain", BRAIN RESEARCH, vol. 784, no. 1-2, 16 February 1998 (1998-02-16), pages 163 - 178, XP008039948, ISSN: 0006-8993 *
OPANASHUK L A ET AL: "Heparin-binding EGF: Modulation of gene expression in vivo and neuroprotective effects in vitro following kainate treatment", SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 22, no. 1-3, 1996, & 26TH ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE; WASHINGTON, D.C., USA; NOVEMBER 16-21, 1996, pages 545, XP008039995, ISSN: 0190-5295 *
PENG HUI ET AL: "Epidermal growth factor protects neuronal cells in vivo and in vitro against transient forebrain ischemia- and free radical-induced injuries", JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, vol. 18, no. 4, April 1998 (1998-04-01), pages 349 - 360, XP008039908, ISSN: 0271-678X *
See also references of WO0007611A1 *

Also Published As

Publication number Publication date
CA2337964A1 (en) 2000-02-17
WO2000007611A1 (en) 2000-02-17
JP2002522394A (en) 2002-07-23
EP1100523A1 (en) 2001-05-23

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Legal Events

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