EP1100950A4 - ANTIBODY FACTORIES OF GASTROINTESTINAL BACTERIA - Google Patents

ANTIBODY FACTORIES OF GASTROINTESTINAL BACTERIA

Info

Publication number
EP1100950A4
EP1100950A4 EP99938901A EP99938901A EP1100950A4 EP 1100950 A4 EP1100950 A4 EP 1100950A4 EP 99938901 A EP99938901 A EP 99938901A EP 99938901 A EP99938901 A EP 99938901A EP 1100950 A4 EP1100950 A4 EP 1100950A4
Authority
EP
European Patent Office
Prior art keywords
gastrointestinal bacteria
antibody factories
factories
antibody
gastrointestinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99938901A
Other languages
German (de)
French (fr)
Other versions
EP1100950A1 (en
Inventor
William E Fahl
Geoffrey J Letchworth
Gerald C Mueller
Adam K Savage
Deborah Loo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of EP1100950A1 publication Critical patent/EP1100950A1/en
Publication of EP1100950A4 publication Critical patent/EP1100950A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP99938901A 1998-07-30 1999-07-29 ANTIBODY FACTORIES OF GASTROINTESTINAL BACTERIA Withdrawn EP1100950A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9469798P 1998-07-30 1998-07-30
US94697P 1998-07-30
PCT/US1999/017296 WO2000006764A1 (en) 1998-07-30 1999-07-29 Gastrointestinal bacterial antibody factories

Publications (2)

Publication Number Publication Date
EP1100950A1 EP1100950A1 (en) 2001-05-23
EP1100950A4 true EP1100950A4 (en) 2002-10-16

Family

ID=22246653

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99938901A Withdrawn EP1100950A4 (en) 1998-07-30 1999-07-29 ANTIBODY FACTORIES OF GASTROINTESTINAL BACTERIA

Country Status (6)

Country Link
EP (1) EP1100950A4 (en)
JP (1) JP2002521494A (en)
AU (1) AU5328599A (en)
CA (1) CA2338001A1 (en)
IL (1) IL141142A0 (en)
WO (1) WO2000006764A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007006086A (en) 2004-11-25 2007-07-11 Unilever Nv Heavy chain and domain antibodies.
EP1915174A1 (en) * 2005-08-19 2008-04-30 Unilever N.V. Food products comprising probiotic micro-organisms and antibodies
JP2010513245A (en) * 2006-12-14 2010-04-30 アクトジェニックス・エヌブイ Delivery of binding molecules to induce immune modulation
WO2012141540A2 (en) * 2011-04-13 2012-10-18 씨제이제일제당 (주) Novel isolated lactobacillus fermentum strain having viral infection inhibitory activity
JP6025127B2 (en) * 2012-07-13 2016-11-16 学校法人帝京平成大学 Antitumor agent, tumor detection marker and oral vaccine
BR112015001175B1 (en) * 2012-07-20 2022-03-03 Elanco Canada Limited Composition comprising an isolated e.coli strain and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021284A1 (en) * 1993-03-15 1994-09-29 Pharma Pacific Pty. Ltd. Therapeutic formulation and method
WO1997020577A1 (en) * 1995-12-06 1997-06-12 Pharma Pacific Pty. Ltd. Improved therapeutic formulation and method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571385A (en) * 1983-06-27 1986-02-18 The United States Of America As Represented By The Department Of Health And Human Services Genetic reassortment of rotaviruses for production of vaccines and vaccine precursors
EP0198086B1 (en) * 1984-09-28 1991-01-16 Teijin Limited Mouse human hybridoma producing antivirus human antibody, process for its preparation, and antivirus human monoclonal antibody
US4956452A (en) * 1987-06-14 1990-09-11 The University Of Maryland Monoclonal antibody which neutralizes multiple strains of infectious bursal disease virus
US5637677A (en) * 1987-07-16 1997-06-10 The Trustees Of The University Of Pennsylvania Biologically active compounds and methods of constructing and using the same
US5531988A (en) * 1994-10-28 1996-07-02 Metagenics, Inc. Bacteria and immunoglobulin-containing composition for human gastrointestinal health
US5733540A (en) * 1995-03-08 1998-03-31 Lee; Peter Poon-Hang Protection from viral infection via colonization of mucosal membranes with genetically modified bacteria
US5895758A (en) * 1997-06-10 1999-04-20 Bio-Energy Systems Strain of lactobacillus Plantarum

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994021284A1 (en) * 1993-03-15 1994-09-29 Pharma Pacific Pty. Ltd. Therapeutic formulation and method
WO1997020577A1 (en) * 1995-12-06 1997-06-12 Pharma Pacific Pty. Ltd. Improved therapeutic formulation and method

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
PLUECKTHUN ANDREAS ET AL: "New protein engineering approaches to multivalent and bispecific antibody fragments.", IMMUNOTECHNOLOGY (SHANNON), vol. 3, no. 2, 1997, pages 83 - 105, XP004126672, ISSN: 1380-2933 *
POUWELS P H ET AL: "Lactic acid bacteria as antigen delivery vehicles for oral immunization purposes.", INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY. NETHERLANDS 26 MAY 1998, vol. 41, no. 2, 26 May 1998 (1998-05-26), pages 155 - 167, XP002209511, ISSN: 0168-1605 *
ROBINSON KAREN ET AL: "Oral vaccination of mice against tetanus with recombinant Lactococcus lactis.", NATURE BIOTECHNOLOGY, vol. 15, no. 7, 1997, pages 653 - 657, XP001093957, ISSN: 1087-0156 *
RUSH C ET AL: "Protein A as a fusion partner for the expression of heterologous proteins in Lactobacillus.", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 47, no. 5, 1997, pages 537 - 542, XP002209512, ISSN: 0175-7598 *
See also references of WO0006764A1 *
SHIBATA YASUKO ET AL: "Construction of a functional single-chain variable fragment antibody against hemagglutinin from Porphyromonas gingivalis.", INFECTION AND IMMUNITY, vol. 66, no. 5, May 1998 (1998-05-01), pages 2207 - 2212, XP001097761, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
EP1100950A1 (en) 2001-05-23
CA2338001A1 (en) 2000-02-10
JP2002521494A (en) 2002-07-16
IL141142A0 (en) 2002-02-10
WO2000006764A1 (en) 2000-02-10
AU5328599A (en) 2000-02-21

Similar Documents

Publication Publication Date Title
NO20006152D0 (en) Chemical connections
ATE220500T1 (en) FAST-ACTING CHEMICAL STERILIZER
NO20002359D0 (en) Chemical connections
NO20002360D0 (en) Chemical connections
DE59503200D1 (en) SOLID CHEMICAL SENSOR
NO20002361D0 (en) Chemical connections
DE69729672D1 (en) biosensor
DK1133352T3 (en) Biological assay technique
NO980154D0 (en) Chemical connections
DE69840196D1 (en) SAMPLE TUBES
NO20020765L (en) Chemical connections
NO20021637D0 (en) Chemical connections
DE59504507D1 (en) CHEMICAL SENSOR
DE69842220D1 (en) IT IMPROVED BACTERIA SEALING
DE69724486D1 (en) Chemical semiconductor sensor
DE69926102D1 (en) differential scanning calorimeter
ID28852A (en) ELECTROLUMINENTIAL MATERIALS
FI972683L (en) Chemical compounds
NO990814D0 (en) Chemical connections
DE69725770D1 (en) Chemical semiconductor sensor
FI955611A0 (en) The sample sensor
DE69617415D1 (en) CANCELED METASTASIS FORMATION SUPPRESSIVE ANTICRECELLENT
EP1100950A4 (en) ANTIBODY FACTORIES OF GASTROINTESTINAL BACTERIA
NO980630D0 (en) Chemical connections
EP1121598A4 (en) DETECTION OF PLEIOTROPHIN

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010207

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

A4 Supplementary search report drawn up and despatched

Effective date: 20020902

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20040203