EP1107702A4 - Ultrasonic enhancement of drug injection - Google Patents

Ultrasonic enhancement of drug injection

Info

Publication number
EP1107702A4
EP1107702A4 EP99937661A EP99937661A EP1107702A4 EP 1107702 A4 EP1107702 A4 EP 1107702A4 EP 99937661 A EP99937661 A EP 99937661A EP 99937661 A EP99937661 A EP 99937661A EP 1107702 A4 EP1107702 A4 EP 1107702A4
Authority
EP
European Patent Office
Prior art keywords
drug injection
ultrasonic enhancement
enhancement
ultrasonic
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99937661A
Other languages
German (de)
French (fr)
Other versions
EP1107702A1 (en
Inventor
Alex Brisken
Robert Zuk
John Mckenzie
Jeff Isner
Meno Nassi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmasonics Inc
Original Assignee
Pharmasonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/126,011 external-priority patent/US6464680B1/en
Application filed by Pharmasonics Inc filed Critical Pharmasonics Inc
Publication of EP1107702A1 publication Critical patent/EP1107702A1/en
Publication of EP1107702A4 publication Critical patent/EP1107702A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP99937661A 1998-07-29 1999-07-29 Ultrasonic enhancement of drug injection Withdrawn EP1107702A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/126,011 US6464680B1 (en) 1998-07-29 1998-07-29 Ultrasonic enhancement of drug injection
US126011 1998-07-29
US25529099A 1999-02-22 1999-02-22
US255290 1999-02-22
PCT/US1999/017305 WO2000006032A1 (en) 1998-07-29 1999-07-29 Ultrasonic enhancement of drug injection

Publications (2)

Publication Number Publication Date
EP1107702A1 EP1107702A1 (en) 2001-06-20
EP1107702A4 true EP1107702A4 (en) 2002-10-09

Family

ID=26824191

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99937661A Withdrawn EP1107702A4 (en) 1998-07-29 1999-07-29 Ultrasonic enhancement of drug injection

Country Status (6)

Country Link
EP (1) EP1107702A4 (en)
JP (1) JP2002521118A (en)
AU (1) AU754022B2 (en)
BR (1) BR9912587A (en)
CA (1) CA2338396A1 (en)
WO (1) WO2000006032A1 (en)

Families Citing this family (54)

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US6050943A (en) 1997-10-14 2000-04-18 Guided Therapy Systems, Inc. Imaging, therapy, and temperature monitoring ultrasonic system
WO2000048518A1 (en) * 1999-02-22 2000-08-24 Pharmasonics, Inc. Methods and apparatus for uniform transcutaneous therapeutic ultrasound
US7914453B2 (en) 2000-12-28 2011-03-29 Ardent Sound, Inc. Visual imaging system for ultrasonic probe
US6623444B2 (en) * 2001-03-21 2003-09-23 Advanced Medical Applications, Inc. Ultrasonic catheter drug delivery method and device
EP1319423A3 (en) * 2001-12-11 2003-10-08 Dornier Medtech System GmbH Apparatus and method for initiating chemical reactions and for the targeted delivery of drugs or other agents
US7358226B2 (en) * 2003-08-27 2008-04-15 The Regents Of The University Of California Ultrasonic concentration of drug delivery capsules
US7393325B2 (en) 2004-09-16 2008-07-01 Guided Therapy Systems, L.L.C. Method and system for ultrasound treatment with a multi-directional transducer
US7824348B2 (en) 2004-09-16 2010-11-02 Guided Therapy Systems, L.L.C. System and method for variable depth ultrasound treatment
US9011336B2 (en) 2004-09-16 2015-04-21 Guided Therapy Systems, Llc Method and system for combined energy therapy profile
US10864385B2 (en) 2004-09-24 2020-12-15 Guided Therapy Systems, Llc Rejuvenating skin by heating tissue for cosmetic treatment of the face and body
US8444562B2 (en) 2004-10-06 2013-05-21 Guided Therapy Systems, Llc System and method for treating muscle, tendon, ligament and cartilage tissue
US8535228B2 (en) 2004-10-06 2013-09-17 Guided Therapy Systems, Llc Method and system for noninvasive face lifts and deep tissue tightening
US9694212B2 (en) 2004-10-06 2017-07-04 Guided Therapy Systems, Llc Method and system for ultrasound treatment of skin
US11883688B2 (en) 2004-10-06 2024-01-30 Guided Therapy Systems, Llc Energy based fat reduction
US11235179B2 (en) 2004-10-06 2022-02-01 Guided Therapy Systems, Llc Energy based skin gland treatment
US7758524B2 (en) 2004-10-06 2010-07-20 Guided Therapy Systems, L.L.C. Method and system for ultra-high frequency ultrasound treatment
US9827449B2 (en) 2004-10-06 2017-11-28 Guided Therapy Systems, L.L.C. Systems for treating skin laxity
KR20170117205A (en) 2004-10-06 2017-10-20 가이디드 테라피 시스템스, 엘.엘.씨. Ultrasound treatment system
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
US20060111744A1 (en) 2004-10-13 2006-05-25 Guided Therapy Systems, L.L.C. Method and system for treatment of sweat glands
US8690779B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Noninvasive aesthetic treatment for tightening tissue
WO2006042163A2 (en) 2004-10-06 2006-04-20 Guided Therapy Systems, L.L.C. Method and system for cosmetic enhancement
US11724133B2 (en) 2004-10-07 2023-08-15 Guided Therapy Systems, Llc Ultrasound probe for treatment of skin
US11207548B2 (en) 2004-10-07 2021-12-28 Guided Therapy Systems, L.L.C. Ultrasound probe for treating skin laxity
EP2533130A1 (en) 2005-04-25 2012-12-12 Ardent Sound, Inc. Method and system for enhancing computer peripheral saftey
US20070232986A1 (en) * 2006-03-31 2007-10-04 Cytodome, Inc. Low-profile implantable ultrasound array and method for enhancing drug delivery to tissue
US9566454B2 (en) 2006-09-18 2017-02-14 Guided Therapy Systems, Llc Method and sysem for non-ablative acne treatment and prevention
EP2152351B1 (en) * 2007-05-07 2016-09-21 Guided Therapy Systems, L.L.C. Methods and systems for modulating medicants using acoustic energy
US20150174388A1 (en) 2007-05-07 2015-06-25 Guided Therapy Systems, Llc Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue
US12102473B2 (en) 2008-06-06 2024-10-01 Ulthera, Inc. Systems for ultrasound treatment
KR102746886B1 (en) 2008-06-06 2024-12-27 얼테라, 인크 Ultrasound treatment system
EP2382010A4 (en) 2008-12-24 2014-05-14 Guided Therapy Systems Llc Methods and systems for fat reduction and/or cellulite treatment
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
KR101939725B1 (en) 2010-08-02 2019-01-17 가이디드 테라피 시스템스, 엘.엘.씨. System and Method for Ultrasound Treatment
US9504446B2 (en) 2010-08-02 2016-11-29 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
US8857438B2 (en) 2010-11-08 2014-10-14 Ulthera, Inc. Devices and methods for acoustic shielding
KR102068724B1 (en) 2011-07-10 2020-01-21 가이디드 테라피 시스템스, 엘.엘.씨. Systems and methods for improving an outside appearance of skin using ultrasound as an energy source
WO2013012641A1 (en) 2011-07-11 2013-01-24 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
US9263663B2 (en) 2012-04-13 2016-02-16 Ardent Sound, Inc. Method of making thick film transducer arrays
US9510802B2 (en) 2012-09-21 2016-12-06 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
CN204017181U (en) 2013-03-08 2014-12-17 奥赛拉公司 Aesthetic imaging and treatment system, multifocal treatment system and system for performing cosmetic procedures
WO2014146022A2 (en) 2013-03-15 2014-09-18 Guided Therapy Systems Llc Ultrasound treatment device and methods of use
AU2015247951A1 (en) 2014-04-18 2016-11-17 Ulthera, Inc. Band transducer ultrasound therapy
CN108367317B (en) 2016-01-18 2020-10-09 奥赛拉公司 Compact ultrasonic device having annular ultrasonic array peripherally electrically connected to flexible printed circuit board and method of assembling same
CA3022003A1 (en) 2016-08-16 2018-02-22 Ulthera, Inc. Systems and methods for cosmetic ultrasound treatment of skin
TWI797235B (en) 2018-01-26 2023-04-01 美商奧賽拉公司 Systems and methods for simultaneous multi-focus ultrasound therapy in multiple dimensions
WO2019164836A1 (en) 2018-02-20 2019-08-29 Ulthera, Inc. Systems and methods for combined cosmetic treatment of cellulite with ultrasound
BR112021006999A2 (en) 2018-11-30 2021-07-20 Ulthera, Inc. systems and methods for improving the effectiveness of ultrasound treatment
KR20220035151A (en) 2019-07-15 2022-03-21 얼테라, 인크 System and device for measuring elasticity by multi-dimensional imaging of ultrasound multifocal shear wave
MX2022003768A (en) * 2019-10-03 2022-08-19 Vitruvia Holdings Inc Method of connective tissue restoration.
JP7598331B2 (en) * 2019-11-18 2024-12-11 株式会社カネカ Drug solution diffusion system and drug solution diffusion promotion device
WO2021101846A1 (en) * 2019-11-18 2021-05-27 Likhacheva M D Anna O System for conforming treatment applicators to non-uniform surfaces
CN112023243B (en) * 2020-09-15 2022-03-25 南京大学 Transdermal drug delivery device with ultrasonic circulating focusing emission and control method
WO2025238754A1 (en) * 2024-05-15 2025-11-20 朝日インテック株式会社 Catheter with puncture needle and medical system using drug solution

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5016615A (en) * 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
US5386837A (en) * 1993-02-01 1995-02-07 Mmtc, Inc. Method for enhancing delivery of chemotherapy employing high-frequency force fields
WO1998018391A1 (en) * 1996-10-30 1998-05-07 Ekos Corporation Intraluminal wall drug delivery device

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
US5197946A (en) * 1990-06-27 1993-03-30 Shunro Tachibana Injection instrument with ultrasonic oscillating element
US5667487A (en) * 1993-04-07 1997-09-16 Henley; Julian L. Ionosonic drug delivery apparatus
US5490840A (en) * 1994-09-26 1996-02-13 General Electric Company Targeted thermal release of drug-polymer conjugates
US5752515A (en) * 1996-08-21 1998-05-19 Brigham & Women's Hospital Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5016615A (en) * 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
US5386837A (en) * 1993-02-01 1995-02-07 Mmtc, Inc. Method for enhancing delivery of chemotherapy employing high-frequency force fields
WO1998018391A1 (en) * 1996-10-30 1998-05-07 Ekos Corporation Intraluminal wall drug delivery device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0006032A1 *

Also Published As

Publication number Publication date
CA2338396A1 (en) 2000-02-10
BR9912587A (en) 2002-06-11
AU754022B2 (en) 2002-10-31
EP1107702A1 (en) 2001-06-20
AU5245099A (en) 2000-02-21
WO2000006032A1 (en) 2000-02-10
JP2002521118A (en) 2002-07-16

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