EP1123501A4 - Methods of concentrating microorganisms using affinity separation - Google Patents

Methods of concentrating microorganisms using affinity separation

Info

Publication number
EP1123501A4
EP1123501A4 EP99943648A EP99943648A EP1123501A4 EP 1123501 A4 EP1123501 A4 EP 1123501A4 EP 99943648 A EP99943648 A EP 99943648A EP 99943648 A EP99943648 A EP 99943648A EP 1123501 A4 EP1123501 A4 EP 1123501A4
Authority
EP
European Patent Office
Prior art keywords
methods
affinity separation
concentrating microorganisms
concentrating
microorganisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99943648A
Other languages
German (de)
French (fr)
Other versions
EP1123501A1 (en
Inventor
Daniel L Siegel
Anthony Saunders
Oded Shoseyov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CBD Technologies Ltd
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
CBD Technologies Ltd
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CBD Technologies Ltd, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical CBD Technologies Ltd
Publication of EP1123501A1 publication Critical patent/EP1123501A1/en
Publication of EP1123501A4 publication Critical patent/EP1123501A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP99943648A 1998-10-19 1999-08-04 Methods of concentrating microorganisms using affinity separation Withdrawn EP1123501A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17504098A 1998-10-19 1998-10-19
US175040 1998-10-19
US30145199A 1999-04-29 1999-04-29
US301451 1999-04-29
PCT/US1999/017589 WO2000023792A1 (en) 1998-10-19 1999-08-04 Methods of concentrating microorganisms using affinity separation

Publications (2)

Publication Number Publication Date
EP1123501A1 EP1123501A1 (en) 2001-08-16
EP1123501A4 true EP1123501A4 (en) 2005-04-13

Family

ID=26870805

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99943648A Withdrawn EP1123501A4 (en) 1998-10-19 1999-08-04 Methods of concentrating microorganisms using affinity separation

Country Status (4)

Country Link
EP (1) EP1123501A4 (en)
AU (1) AU5670299A (en)
CA (1) CA2347004A1 (en)
WO (1) WO2000023792A1 (en)

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CN1320631A (en) * 2000-04-27 2001-11-07 上海博德基因开发有限公司 Polypeptide-human protein 10 containing cellulose binding structural domain and polynucleotide for coding it
GB0010910D0 (en) * 2000-05-05 2000-06-28 Jones Osborn Analytical method and apparatus
EP1360274B1 (en) 2001-02-05 2007-07-04 Millipore Corporation Detection of micro-organisms
EP1253203A1 (en) * 2001-04-25 2002-10-30 Becton Dickinson and Company Rapid resuscitation, growth, capture and detection of microorganisms
GB0112428D0 (en) * 2001-05-22 2001-07-11 Secr Defence Brit Identifying micro-organisms
US20030022358A1 (en) * 2001-05-29 2003-01-30 Hall Jane H. Growth of filterable organisms that require non-diffusable media components
DE10129815A1 (en) * 2001-06-24 2003-01-09 Profos Ag Process for the purification of bacterial cells and cell components
EP1575507A2 (en) 2002-04-02 2005-09-21 Scantibodies Laboratory, Inc. Methods and devices for treating severe peripheral bacterial infections
GB2387130A (en) 2002-04-04 2003-10-08 Fluid Technologies Plc Hollow fibre filter membrane unit with microorganism detector, and associated usage
WO2007001915A2 (en) * 2005-06-20 2007-01-04 Scantibodies Laboratory, Inc. Methods and devices for removing pathogens and detrimental substances from bodily fluids
WO2007069983A1 (en) 2005-12-13 2007-06-21 Exthera Ab Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood
WO2008072242A2 (en) * 2006-12-14 2008-06-19 Technion Research & Development Foundation Ltd. Compositions and methods for concentrating and depleting microorganisms
CN101215598B (en) * 2008-01-11 2010-11-17 中华人民共和国吉林出入境检验检疫局 Method for detecting bacteria by using immunity enrichment thread, and immunity enrichment brush
BRPI0918694A2 (en) * 2008-12-31 2015-12-01 3M Innovative Properties Co coliform detection process and kit for use
JP2012513768A (en) 2008-12-31 2012-06-21 スリーエム イノベイティブ プロパティズ カンパニー Sampling apparatus and method for concentrating microorganisms
JP5925693B2 (en) 2009-12-01 2016-05-25 エクステラ・メディカル・コーポレーション Method for removing cytokines from blood using surface-immobilized polysaccharides
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
CN104284984B (en) * 2012-02-29 2017-10-13 哈佛大学校长及研究员协会 Rapid Test for Antibiotic Susceptibility
ES2647577T3 (en) 2012-06-13 2017-12-22 Exthera Medical Corporation Use of heparin and carbohydrates to treat cancer
CN105339067A (en) 2013-06-24 2016-02-17 艾克塞拉医疗公司 Blood filtration system containing a mannose-coated matrix
EP3065796B1 (en) * 2013-11-08 2020-04-15 ExThera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
JP2017513636A (en) 2014-04-24 2017-06-01 エクスセラ メディカル コーポレイション Method for removing bacteria from blood using high flow rate
CA2959975A1 (en) 2014-09-22 2016-03-31 Exthera Medical Corporation Wearable hemoperfusion device
WO2017151797A1 (en) 2016-03-02 2017-09-08 Exthera Medical Corporation Method for treating drug intoxication
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
FR3056294B1 (en) * 2016-09-20 2020-02-14 Kabcyt DEVICE FOR CAPTURING BIOLOGICAL PARTICLES
CN113825517A (en) 2019-05-16 2021-12-21 艾克塞拉医疗公司 Methods of modulating endothelial glycocalyx structure
CN119318642B (en) * 2024-12-19 2025-03-07 深圳万可森生物科技有限公司 Nanometer starch granule medicine carrying system and application thereof in preventing and controlling aquatic animal diseases

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DE2825636A1 (en) * 1978-06-12 1979-12-20 Boehringer Mannheim Gmbh DEVICE FOR MICROBIOLOGICAL WORK
US4563418A (en) * 1982-04-09 1986-01-07 Bio-Controls Systems, Inc. Process for detection of selected motile organisms
US5415997A (en) * 1987-07-28 1995-05-16 Biotechnology Australia Pty Limited Method for detecting low levels of microorganisms
JPH04228097A (en) * 1990-07-02 1992-08-18 Toyo Ink Mfg Co Ltd Method for separating and concentrating cell from milk sample and kit therefor
US5232838A (en) * 1991-12-09 1993-08-03 Minnesota Mining And Manufacturing Company Culture media device and method of use
US5314855A (en) * 1992-11-09 1994-05-24 Akzo N.V. Adsorbent compositions and methods of manufacture
US5496934A (en) * 1993-04-14 1996-03-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acids encoding a cellulose binding domain
KR100230909B1 (en) * 1993-11-29 1999-12-01 다니엘 엘. 캐시앙 Methods of Extracting Nucleic Acids from a Wide Range of Organisms
US5681712A (en) * 1995-06-02 1997-10-28 Minnesota Mining And Manufacturing Company Surface colony counting device and method of use
US5807694A (en) * 1995-09-07 1998-09-15 Economic Innovation And Technology Council, University Of Manitoba Detection of salmonella enteritidis and other pathogenic microorganisms and monoclonal antibody useful therefor
US5612473A (en) * 1996-01-16 1997-03-18 Gull Laboratories Methods, kits and solutions for preparing sample material for nucleic acid amplification
US5820767A (en) * 1996-07-29 1998-10-13 Pall Corporation Method for quantitation of microorganism contamination of liquids

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
FRANCISCO J A ET AL: "SPECIFIC ADHESION AND HYDROLYSIS OF CELLULOSE BY INTACT ESCHERICHIACOLI EXPRESSING SURFACE ANCHORED CELLULASE OR CELLULOSE BINDING DOMAINS", BIO/TECHNOLOGY, NATURE PUBLISHING, NEW YORK, NY, US, vol. 11, April 1993 (1993-04-01), pages 491 - 496, XP002947290, ISSN: 0733-222X *
LINDER M ET AL: "The roles and function of cellulose-binding domains", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 57, no. 1-3, 16 September 1997 (1997-09-16), pages 15 - 28, XP004097727, ISSN: 0168-1656 *
See also references of WO0023792A1 *
TOMME P ET AL: "Characterization and affinity applications of cellulose-binding domains", JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL SCIENCES & APPLICATIONS, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 715, no. 1, 11 September 1998 (1998-09-11), pages 283 - 296, XP004147002, ISSN: 1570-0232 *
WIERZBA ANDREW ET AL: "Production and Properties of a Bifunctional Fusion Protein that Mediates Attachment of Vero Cells to Cellulosic Matrices", BIOTECHNOLOGY AND BIOENGINEERING, vol. 47, no. 2, 1995, pages 147 - 154, XP002307744, ISSN: 0006-3592 *

Also Published As

Publication number Publication date
AU5670299A (en) 2000-05-08
WO2000023792A1 (en) 2000-04-27
EP1123501A1 (en) 2001-08-16
CA2347004A1 (en) 2000-04-27

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