EP1124985A4 - OXIDATION STRESS BIOMARKERS - Google Patents

OXIDATION STRESS BIOMARKERS

Info

Publication number: EP1124985A4
Authority: EP; European Patent Office
Prior art keywords: oxidation stress; stress biomarkers; biomarkers; oxidation; stress
Prior art date: 1998-11-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP99971864A

Other languages

German (de)

French (fr)

Other versions

EP1124985A1 (en

Inventor

Joseph M Kinkade Jr

Raymond Shapira

Peter E Jensen

Ngoc-Anh Le

Jan Pohl

W Virgil Brown

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Emory University

Original Assignee

Emory University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-06

Filing date

1999-11-05

Publication date

2003-01-15

1999-11-05 Application filed by Emory University filed Critical Emory University

2001-08-22 Publication of EP1124985A1 publication Critical patent/EP1124985A1/en

2003-01-15 Publication of EP1124985A4 publication Critical patent/EP1124985A4/en

Status Ceased legal-status Critical Current

Links

239000000090 biomarker Substances 0.000 title 1
230000003647 oxidation Effects 0.000 title 1
238000007254 oxidation reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Biotechnology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Peptides Or Proteins (AREA)

EP99971864A 1998-11-06 1999-11-05 OXIDATION STRESS BIOMARKERS Ceased EP1124985A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US10740498P	1998-11-06	1998-11-06
US107404P		1998-11-06
PCT/US1999/026133 WO2000028072A1 (en)	1998-11-06	1999-11-05	Biomarkers for oxidative stress

Publications (2)

Publication Number	Publication Date
EP1124985A1 EP1124985A1 (en)	2001-08-22
EP1124985A4 true EP1124985A4 (en)	2003-01-15

Family

ID=22316499

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP99971864A Ceased EP1124985A4 (en)	1998-11-06	1999-11-05	OXIDATION STRESS BIOMARKERS

Country Status (4)

Country	Link
EP (1)	EP1124985A4 (en)
AU (1)	AU1243500A (en)
CA (1)	CA2348685A1 (en)
WO (1)	WO2000028072A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040029208A1 (en) *	2000-05-30	2004-02-12	Ravn Helle Weber	Assay method and kit for testing biological material for exposure to stress using biomarkers
DE10051983A1 (en)	2000-10-20	2002-06-13	Beate Kehrel	Medicaments useful e.g. for preventing thrombosis, inhibiting transplant rejection or treating chronic inflammatory reactions comprises agents inhibiting binding of oxidized proteins to CD36,
EP1994941A3 (en) *	2000-10-20	2012-07-25	Hamburger Stiftung zur Förderung von Wissenschaft und Kultur	Medicine containing at least one oxidised protein
AU2003232872A1 (en)	2002-05-27	2003-12-12	Ostergotlands Lans Landsting	Method for determining immune system affecting compounds
GB0329288D0 (en)	2003-12-18	2004-01-21	Inverness Medical Switzerland	Monitoring method and apparatus
SE0402536D0 (en)	2004-10-20	2004-10-20	Therim Diagnostica Ab	Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
EP1875246B1 (en)	2005-04-15	2016-10-05	CanImGuide Therapeutics AB	Diagnostic method for detecting cancer by measuring amount of a cytokine like il-6
ES2608803T3 (en)	2007-05-08	2017-04-17	Canimguide Therapeutics Ab	Immunoregulatory structures from natural proteins
JP2010183843A (en) *	2009-02-10	2010-08-26	National Institute Of Advanced Industrial Science & Technology	Antibody against oxidation type polypeptide containing oxidized sulfur-containing amino acid residue
WO2012018535A2 (en)	2010-07-26	2012-02-09	Wellness Indicators, Inc.	Wellness panel
WO2014201451A1 (en) *	2013-06-14	2014-12-18	Wellmetris Llc	Stress and inflammation biomarker urine panel for dairy cows and beef cattle
CA2832215A1 (en)	2013-07-18	2015-01-18	Northern Sydney Local Health District	Biomarkers of oxidative stress

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996004311A1 (en) *	1994-08-03	1996-02-15	University Of Alabama At Birmingham Research Foundation	Monoclonal antibody to nitrotyrosine, methods for diagnosis and methods for treatment of disease
WO1997011371A1 (en) *	1995-09-19	1997-03-27	Cytochem, Inc.	Detection and quantitation of 8-oh-adenine using monoclonal antibodies
WO1998012561A1 (en) *	1996-09-20	1998-03-26	Atherogenics, Inc.	Diagnostics for and mediators of inflammatory disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4859613A (en) *	1986-11-12	1989-08-22	Lawrence David A	Immunoassays for glutathione and antibodies useful therein
US5508031A (en) *	1986-11-21	1996-04-16	Cetus Oncology Corporation	Method for treating biological damage using a free-radial scavenger and interleukin-2
WO1992022668A1 (en) *	1991-06-14	1992-12-23	Vanderbilt University	Method and compositions to assess oxidative stress in vivo
KR100300932B1 (en) *	1992-07-06	2001-10-22	조이스 브린톤	Method and diagnostic kit for measuring toxicity using strain promoter of bacteria fused to reporter gene
US5605826A (en) *	1994-06-10	1997-02-25	Panorama Research, Inc.	24 kilodalton cytoplasmic protease activating DNA fragmentation in apoptosis
US5814300A (en) *	1995-03-03	1998-09-29	Cephalon, Inc.	Gene-targeted non-human mammals deficient in the SOD-1 gene

1999
- 1999-11-05 EP EP99971864A patent/EP1124985A4/en not_active Ceased
- 1999-11-05 AU AU12435/00A patent/AU1243500A/en not_active Abandoned
- 1999-11-05 CA CA002348685A patent/CA2348685A1/en not_active Abandoned
- 1999-11-05 WO PCT/US1999/026133 patent/WO2000028072A1/en not_active Ceased

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996004311A1 (en) *	1994-08-03	1996-02-15	University Of Alabama At Birmingham Research Foundation	Monoclonal antibody to nitrotyrosine, methods for diagnosis and methods for treatment of disease
WO1997011371A1 (en) *	1995-09-19	1997-03-27	Cytochem, Inc.	Detection and quantitation of 8-oh-adenine using monoclonal antibodies
WO1998012561A1 (en) *	1996-09-20	1998-03-26	Atherogenics, Inc.	Diagnostics for and mediators of inflammatory disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AHMAD J ET AL: "DETECTION OF OXIDATIVE DNA DAMAGE BY A MONOCLONAL ANTIBODY: ROLE OF LYSYL RESIDUES IN ANTIGEN BINDING", IMMUNOLOGY LETTERS, AMSTERDAM, NL, vol. 62, no. 2, June 1998 (1998-06-01), pages 87 - 92, XP001118007, ISSN: 0165-2478 *
See also references of WO0028072A1 *

Also Published As

Publication number	Publication date
AU1243500A (en)	2000-05-29
WO2000028072A1 (en)	2000-05-18
CA2348685A1 (en)	2000-05-18
WO2000028072A9 (en)	2000-09-21
EP1124985A1 (en)	2001-08-22

Legal Events

Date	Code	Title	Description
2001-07-06	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2001-08-22	17P	Request for examination filed	Effective date: 20010606
2001-08-22	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2001-08-22	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
2003-01-15	A4	Supplementary search report drawn up and despatched	Effective date: 20021204
2003-01-15	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2003-01-15	RIC1	Information provided on ipc code assigned before grant	Free format text: 7C 12Q 1/68 A, 7C 07C 61/06 B, 7C 12N 1/21 B, 7C 12N 9/64 B, 7G 01N 33/68 B
2006-11-22	17Q	First examination report despatched	Effective date: 20050906
2009-09-11	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2009-10-14	18R	Application refused	Effective date: 20090607

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