EP1283037A4 - Remedies - Google Patents

Remedies

Info

Publication number
EP1283037A4
EP1283037A4 EP01919859A EP01919859A EP1283037A4 EP 1283037 A4 EP1283037 A4 EP 1283037A4 EP 01919859 A EP01919859 A EP 01919859A EP 01919859 A EP01919859 A EP 01919859A EP 1283037 A4 EP1283037 A4 EP 1283037A4
Authority
EP
European Patent Office
Prior art keywords
salts
remedies
polyphenols
derivatives
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01919859A
Other languages
German (de)
French (fr)
Other versions
EP1283037A1 (en
Inventor
Hiromu Ohnogi
Eiji Kobayashi
Kaori Nishimura
Masahiro Shiraga
Tuo-Ping Li
Hiroaki Sagawa
Ikunoshin Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takara Bio Inc
Original Assignee
Takara Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Bio Inc filed Critical Takara Bio Inc
Publication of EP1283037A1 publication Critical patent/EP1283037A1/en
Publication of EP1283037A4 publication Critical patent/EP1283037A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/20Natural extracts
    • A23V2250/21Plant extracts
    • A23V2250/2132Other phenolic compounds, polyphenols

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nutrition Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Remedies or preventives for diseases, wherein the production of growth factor should be potentiated, and foods, drinks or feeds for potentiating the production of growth factor each containing, as the active ingredient, polyphenols, derivatives thereof and/or salts thereof or compositions obtained by subjecting polyphenols, derivatives thereof and/or salts thereof to (i) mixing with metals, metal salts and/or metal ions, or (ii) oxidization.
EP01919859A 2000-04-11 2001-04-10 Remedies Withdrawn EP1283037A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2000109983 2000-04-11
JP2000109983 2000-04-11
JP2000308525 2000-10-06
JP2000308524 2000-10-06
JP2000308524 2000-10-06
JP2000308525 2000-10-06
PCT/JP2001/003075 WO2001076580A1 (en) 2000-04-11 2001-04-10 Remedies

Publications (2)

Publication Number Publication Date
EP1283037A1 EP1283037A1 (en) 2003-02-12
EP1283037A4 true EP1283037A4 (en) 2006-02-22

Family

ID=27343061

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01919859A Withdrawn EP1283037A4 (en) 2000-04-11 2001-04-10 Remedies

Country Status (7)

Country Link
US (1) US20030203857A1 (en)
EP (1) EP1283037A4 (en)
KR (1) KR20020089440A (en)
CN (1) CN1436074A (en)
AU (1) AU2001246877A1 (en)
TW (1) TWI233353B (en)
WO (1) WO2001076580A1 (en)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1277473A4 (en) * 2000-04-10 2005-12-28 Takara Bio Inc TOOLS
US6555573B2 (en) 2000-12-21 2003-04-29 The Quigley Corporation Method and composition for the topical treatment of diabetic neuropathy
EP1386919A4 (en) * 2001-04-10 2010-03-10 Takara Bio Inc Remedies
EP1415657A4 (en) * 2001-07-13 2005-09-14 Takara Bio Inc TREATMENT DRUGS
EP1455778A4 (en) * 2001-12-19 2007-09-12 The Quigley Corp METHODS OF TREATING PERIPHERAL NEUROVASCULAR MALAYS
US7108868B2 (en) 2002-03-22 2006-09-19 Unigen Pharmaceuticals, Inc. Isolation of a dual cox-2 and 5-lipoxygenase inhibitor from acacia
US7972632B2 (en) 2003-02-28 2011-07-05 Unigen Pharmaceuticals, Inc. Identification of Free-B-Ring flavonoids as potent COX-2 inhibitors
KR20030075947A (en) * 2002-03-19 2003-09-26 제네티카 주식회사 Angiogenesis inhibitor
EP1503633A1 (en) * 2002-04-24 2005-02-09 Unilever N.V. Use of hop components in foods
US8034387B2 (en) 2002-04-30 2011-10-11 Unigen, Inc. Formulation of a mixture of free-B-ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments
DE60328676D1 (en) 2002-04-30 2009-09-17 Unigen Pharmaceuticals Inc FORMULATION OF A MIXTURE OF FLAVONOIDS AND FLAVANES WITH FREE B RING AS A THERAPEUTIC AGENT
WO2004004708A1 (en) * 2002-07-08 2004-01-15 Council Of Scientific And Industrial Research A pharmaceutical composition useful for treating chronic myeloid leukemia
KR20030097398A (en) * 2002-06-21 2003-12-31 이노천 A sauce for seasoned meat containing polyphenol
CN100506813C (en) * 2002-10-01 2009-07-01 宝生物工程株式会社 New chalcones and their applications
US7083813B2 (en) 2002-11-06 2006-08-01 The Quigley Corporation Methods for the treatment of peripheral neural and vascular ailments
AU2003277630A1 (en) * 2002-11-12 2004-06-03 Takara Bio Inc. Agent for improving learning and memorizing abilities
AU2003289290A1 (en) * 2002-12-05 2004-06-23 Takara Bio Inc. Remedy
DK1431385T3 (en) * 2002-12-18 2006-07-31 Doehler Gmbh Xanthohumol-containing beverage
JP4684893B2 (en) * 2003-03-27 2011-05-18 ユニジェン インク. Bamboo extract showing a therapeutic and preventive activity for inflammatory and blood circulation diseases and a composition containing a compound isolated therefrom
EP1631304A4 (en) 2003-04-04 2007-03-21 Unigen Pharmaceuticals Inc FORMULATION FOR INHIBITING CYCLOOXYGENASE (COX) AND LIPOXYGENASE (LOX) FOR SKIN CARE
JPWO2004089359A1 (en) * 2003-04-08 2006-07-06 麒麟麦酒株式会社 Composition for inhibiting or preventing decrease in bone density and food and drink
JP4571783B2 (en) * 2003-04-14 2010-10-27 林原 健 Antimicrobial agent
JPWO2004096198A1 (en) * 2003-05-02 2006-07-13 タカラバイオ株式会社 Therapeutic agent
WO2004100969A1 (en) * 2003-05-19 2004-11-25 Takara Bio Inc. Remedy
JP2005272355A (en) * 2004-03-25 2005-10-06 Tsuno Rice Fine Chemicals Co Ltd Brain function improver
KR100720971B1 (en) * 2004-06-11 2007-05-22 주식회사 유니젠 Androgen Efficacy Composition Containing Bamboo or Bamboo Extract
KR100720973B1 (en) * 2005-03-18 2007-05-22 주식회사 유니젠 Histamine inhibitory pharmaceutical composition comprising natural iso-orientin
EP2368442B1 (en) 2005-07-27 2014-12-17 Symrise AG Use of hesperetin for enhancing the sweet taste
JP4990534B2 (en) * 2006-02-02 2012-08-01 ポーラ化成工業株式会社 Caffeoylquinic acid derivative and composition for suppressing plasminogen activator inhibitor comprising the same as an active ingredient
JP4856471B2 (en) * 2006-05-18 2012-01-18 花王株式会社 Tetrahydrobiopterin production promoter
EP1856988B1 (en) * 2006-05-19 2017-09-13 Kraft Foods R & D, Inc. Flavonoid sugar addition products, method for manufacture and use thereof
KR100761248B1 (en) * 2006-10-12 2007-10-04 주식회사 유니젠 Composition for the treatment of atopic dermatitis containing bamboo and golden extract as active ingredients
JP5638180B2 (en) 2007-09-06 2014-12-10 富士フイルム株式会社 Foods containing Salacia plant extracts and flavonoids
EP3381445B1 (en) 2007-11-15 2023-10-25 Amgen Inc. Aqueous formulation of antibody stablised by antioxidants for parenteral administration
CN101966172B (en) * 2009-07-28 2012-03-07 成都中医药大学 New purpose of caffeic acid and derivatives thereof
JP5744471B2 (en) * 2010-10-22 2015-07-08 花王株式会社 Bitter taste inhibitor
CN104936587A (en) 2012-12-26 2015-09-23 株式会社Az Wound healing accelerator
GB201317286D0 (en) * 2013-09-30 2013-11-13 Calscience Internat Ltd Composition and Use
CN104352457A (en) * 2014-11-24 2015-02-18 四川九章生物科技有限公司 Chlorogenic acid crystal form-containing preparation and application thereof
GB201502268D0 (en) 2015-02-11 2015-04-01 Calscience Internat Ltd Dental composition and use
JP2018145100A (en) * 2017-03-01 2018-09-20 富士フイルム株式会社 Brain-derived neurotrophic factor production improver and food and drink
IL283127B1 (en) * 2018-11-14 2026-02-01 Smilebiotek Zhuhai Ltd Animal models, screening methods, and treatment methods for intraocular diseases or disorders
CA3120397C (en) * 2018-11-19 2024-01-23 Xianfeng PENG Applications of diphenylpropenone compound in preparing animal feed additive or animal feed
JP7443361B2 (en) * 2018-12-03 2024-03-05 珠海岐微生物科技有限公司 How to treat age-related macular degeneration
US11964929B2 (en) 2018-12-18 2024-04-23 Wisorig Technologies Pte. Limited Application of glutamine derivative in preparation of animal feed additive
CN111718390B (en) * 2020-07-28 2023-06-16 福建省格兰尼生物工程股份有限公司 Sterol cold precipitation formula liquid and application thereof
CN114424798A (en) * 2022-01-24 2022-05-03 斯卡恩动物保健品(商丘)有限公司 Preparation method and application of feed additive caffeic acid chelated zinc

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1013249B (en) * 1953-08-31 1957-08-08 F Wilhelm Schick Dipl Kfm Process for the production of a long-lasting, optimal quantities of isohumulone-containing dry hops for export purposes
JPH01151514A (en) * 1987-12-09 1989-06-14 Nichirei Corp Neurological disease treatment/prevention agent
EP0399814A2 (en) * 1989-05-23 1990-11-28 Sankyo Company Limited Phenol derivatives for promoting human nerve growth factor
US5210076A (en) * 1988-09-13 1993-05-11 Berliner David L Methods of treating Parkinson's disease using melanin
JPH05201860A (en) * 1992-01-28 1993-08-10 Kitsuen Kagaku Kenkyu Zaidan Agent for accelerating biological synthesis of nervous growth factor
US5643925A (en) * 1991-02-21 1997-07-01 Sankyo Company, Limited Benzene derivatives having NGF production-promoting activity
WO2001010987A1 (en) * 1999-08-05 2001-02-15 VITIS Ölmühlen KG Grapeseed, cold-pressed grape oil, crushed grape and grape flour
EP1254658A1 (en) * 2000-01-27 2002-11-06 Takara Bio Inc. Remedies

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2486523A1 (en) * 1980-07-11 1982-01-15 Rhone Poulenc Ind PROCESS FOR THE PREPARATION OF POLYPHENOLS WHICH MAY INCLUDE ALDEHYDE GROUP
JPS63132662A (en) * 1986-11-25 1988-06-04 松下電工株式会社 Deodorant
JPS6468318A (en) * 1987-09-08 1989-03-14 Ota Isan Kk Prophylactic improver or hepatic function disorder
EP0481263B1 (en) * 1990-10-15 1994-02-16 Societe Des Produits Nestle S.A. Oxidation of tea
JPH07110812B2 (en) * 1990-12-11 1995-11-29 財団法人喫煙科学研究財団 Nerve growth factor biosynthesis promoter
US5478579A (en) * 1991-02-06 1995-12-26 Biodyn Medical Research, Inc. Method for treatment of osteoporosis
JPH0578384A (en) * 1991-03-27 1993-03-30 Taisho Pharmaceut Co Ltd Flavonol derivative
JP3130327B2 (en) * 1991-03-29 2001-01-31 日鉱金属株式会社 Liver dysfunction preventive agent and functional food having hepatic dysfunction preventive action
DE4444238A1 (en) * 1994-12-13 1996-06-20 Beiersdorf Ag Cosmetic or dermatological drug combinations of cinnamic acid derivatives and flavone glycosides
CZ97399A3 (en) * 1996-09-20 1999-08-11 The Howard Foundation Food supplement containing flavonol
JPH10175990A (en) * 1996-12-13 1998-06-30 Yamanouchi Pharmaceut Co Ltd New tetrahydroxanthone compound
JPH10175858A (en) * 1996-12-13 1998-06-30 Itouen:Kk Active oxygen generation inhibitor and active oxygen-induced disease preventive agent
JPH10245342A (en) * 1997-03-03 1998-09-14 Mitsui Norin Kk Agent for reducing neurotoxicity of β-amyloid protein
JPH1180009A (en) * 1997-09-12 1999-03-23 Seiwa Yakuhin Kk Agent for improving brain function and agent for preventing lowering of brain function
FR2778663B1 (en) * 1998-05-15 2001-05-18 Coletica NOVEL ESTERS OF FLAVONOIDS, THEIR USE IN COSMETICS, DERMOPHARMACY, PHARMACY AND AGRI-FOOD
JP4309496B2 (en) * 1998-08-05 2009-08-05 株式会社アミノアップ化学 Composition for preventing and / or treating aging
JP2000060427A (en) * 1998-08-19 2000-02-29 Howaizu:Kk Healthy black tea beverage

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1013249B (en) * 1953-08-31 1957-08-08 F Wilhelm Schick Dipl Kfm Process for the production of a long-lasting, optimal quantities of isohumulone-containing dry hops for export purposes
JPH01151514A (en) * 1987-12-09 1989-06-14 Nichirei Corp Neurological disease treatment/prevention agent
US5210076A (en) * 1988-09-13 1993-05-11 Berliner David L Methods of treating Parkinson's disease using melanin
EP0399814A2 (en) * 1989-05-23 1990-11-28 Sankyo Company Limited Phenol derivatives for promoting human nerve growth factor
US5643925A (en) * 1991-02-21 1997-07-01 Sankyo Company, Limited Benzene derivatives having NGF production-promoting activity
JPH05201860A (en) * 1992-01-28 1993-08-10 Kitsuen Kagaku Kenkyu Zaidan Agent for accelerating biological synthesis of nervous growth factor
WO2001010987A1 (en) * 1999-08-05 2001-02-15 VITIS Ölmühlen KG Grapeseed, cold-pressed grape oil, crushed grape and grape flour
EP1254658A1 (en) * 2000-01-27 2002-11-06 Takara Bio Inc. Remedies

Non-Patent Citations (14)

* Cited by examiner, † Cited by third party
Title
ACTA MEDICA ROMANA 1994 ITALY, vol. 32, no. 4, 1994, pages 566 - 572, ISSN: 0001-6098 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1993, LAROCCA L M ET AL: "Quercetin enhances the production of transforming growth factor-beta-1 in human ovarian cancer cells and acute leukemias", XP002353792, Database accession no. PREV199345050071 *
DATABASE EMBASE [online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; 1994, FERRANDINA G ET AL: "Quercetin induces transforming growth factor [beta]1 secretion by human ovarian cancer cells", XP002353793, Database accession no. EMB-1995121851 *
DATABASE FSTA [online] INTERNATIONAL FOOD INFORMATION SERVICE (IFIS), FRANkFURT-MAIN, DE; 1970, HARPER K A: "Copper-flavonoid complexes in acidic solutions.", XP002333923, Database accession no. 70-4-05-h0625 *
DATABASE FSTA [online] INTERNATIONAL FOOD INFORMATION SERVICE (IFIS), FRANkFURT-MAIN, DE; 1984, MIYOSHI H: "Studies on softening of brined vegetables. II. Effect of added salts on texture of brined vegetable in misozuke.", XP002333922, Database accession no. 84-2-04-j0692 *
DATABASE WPI Section Ch Week 198930, Derwent World Patents Index; Class B05, AN 1989-215492, XP002333924 *
FINGER A: "in vitro studies on the effect of polyphenol oxidase a. peroxidase on the formation of polyphenolic black tea constituents", JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, WILEY & SONS, CHICHESTER, GB, vol. 66, no. 3, 1994, pages 293 - 305, XP002312128, ISSN: 0022-5142 *
HARPER K A: "Copper-flavonoid complexes in acidic solutions", JOURNAL OF FOOD TECHNOLOGY, vol. 4, no. 4, 1969, BLACKWELL, GB, pages 405 - 407 *
KELLOFF G J ET AL: "PROGRESS IN CANCER CHEMOPREVENTION: DEVELOPMENT OF DIET-DERIVED CHEMOPREVENTIVE AGENTS", JOURNAL OF NUTRITION, WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, PHILADELPHIA, PA,, US, vol. 130, no. 2S, 2000, pages 467S - 471S, XP001028660, ISSN: 0022-3166 *
MIYOSHI H: "Studies on softening of brined vegetables. II. Effect of added salts on texture of brined vegetable in misozuke.", JOURNAL OF JAPANESE SOCIETY OF FOOD SCIENCE AND TECHNOLOGY ((NIPPON SHOKUHIN KOGYO GAKKAISHI)), vol. 29, no. 10, 1982, 2220 BUSHOZAN-CHO, TAKAMATSU-SHI, KAGAWA-KEN, 761 JAPAN, pages 577 *
PATENT ABSTRACTS OF JAPAN vol. 017, no. 644 (C - 1134) 30 November 1993 (1993-11-30) *
PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL MEETING, vol. 34, no. 0, 1993, 84TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH; ORLANDO, FLORIDA, USA; MAY 19-22, 1993, pages 220, ISSN: 0197-016X *
See also references of WO0176580A1 *
SHOAB S S ET AL: "PLASMA VEGF AS A MARKER OF THERAPY IN PATIENTS WITH CHRONIC VENOUS DISEASE TREATED WITH ORAL MICRONISED FLAVONOID FRACTION - A PILOT STUDY", EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, SAUNDERS, LONDON,, GB, vol. 18, no. 4, October 1999 (1999-10-01), pages 334 - 338, XP008014344, ISSN: 1078-5884 *

Also Published As

Publication number Publication date
US20030203857A1 (en) 2003-10-30
TWI233353B (en) 2005-06-01
CN1436074A (en) 2003-08-13
EP1283037A1 (en) 2003-02-12
WO2001076580A1 (en) 2001-10-18
AU2001246877A1 (en) 2001-10-23
KR20020089440A (en) 2002-11-29

Similar Documents

Publication Publication Date Title
EP1277473A4 (en) TOOLS
WO2002041882A3 (en) Combination comprising an agent decreasing vegf activity and an agent decreasing egf activity
WO2001095856A3 (en) Urea derivative useful as an anti-cancer agent and process for preparing same
WO2005000232A3 (en) Six membered amino-amide derivatives as angiogenesis inhibitors
WO2006096434A3 (en) Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders
WO2005113553A3 (en) Azinyl imidazoazine and azinyl carboxamide
WO2002074238A3 (en) Water soluble and palatable complexes
WO2001058412A3 (en) Extracts from residues left in the production of wine
AU2001271545A1 (en) Promoting whole body health
WO2004026836A3 (en) 1-pyridin-4-yl-urea derivatives
HUP0400527A3 (en) Benzoylpyridine derivative or its salt, fungicide containing it as an active ingredient, its production process and intermediate for producing it
AU2001262011A1 (en) A complex between folic acid and polysaccharides, its preparation method and a pharmaceutical composition comprising said complex as active component
AU5895496A (en) Phenyldihydrobenzofurans
WO2000053149A3 (en) Method and composition for administering a cyclooxygenase-2 inhibitor
WO2000054754A3 (en) Composition comprising isoquercetin and ascorbic acid in a sustained release form
WO2002091858A8 (en) Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods
WO2006062847A3 (en) Compositions having a high antiviral and antibacterial efficacy
TWI256292B (en) Reduction inhibitory agent for active oxygen eliminating activity
EP1415658A4 (en) REMEDIES
AU2001228825A1 (en) Remedies
WO2004073675A8 (en) Cosmetic composition with a whitening effect, method for the production and use thereof
AU2002222589A1 (en) Oral preprations having itching-relievign or antipruritic activity
HUP0600084A2 (en) Pharmaceutical compositions containing ascorbic acid derivatives, methods of production of the active ingredient
EP1354584A4 (en) ARTHRITIS PROPHYLACTIC AGENTS
CA2505500A1 (en) Method of stimulating hair growth using benzopyrans

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20021111

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIN1 Information on inventor provided before grant (corrected)

Inventor name: KATO, IKUNOSHIN

Inventor name: SAGAWA, HIROAKI

Inventor name: LI, TUO-PING,C/O CENTRAL RES. LAB.

Inventor name: SHIRAGA, MASAHIRO

Inventor name: NISHIMURA, KAORI

Inventor name: KOBAYASHI, EIJI

Inventor name: OHNOGI, HIROMU

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 23L 1/304 B

Ipc: 7A 23L 1/30 B

Ipc: 7A 61P 43/00 B

Ipc: 7A 61P 1/16 B

Ipc: 7A 61P 25/00 B

Ipc: 7A 61K 31/7024 B

Ipc: 7A 61K 31/352 B

Ipc: 7A 61K 31/216 B

Ipc: 7A 61K 31/12 A

A4 Supplementary search report drawn up and despatched

Effective date: 20060105

17Q First examination report despatched

Effective date: 20061218

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070501