EP1421097A4 - COMPOSITIONS AND METHODS CONCERNING THE DAPTOMYCIN BIOSYNTHESEGENCLUSTER - Google Patents

COMPOSITIONS AND METHODS CONCERNING THE DAPTOMYCIN BIOSYNTHESEGENCLUSTER

Info

Publication number
EP1421097A4
EP1421097A4 EP02759231A EP02759231A EP1421097A4 EP 1421097 A4 EP1421097 A4 EP 1421097A4 EP 02759231 A EP02759231 A EP 02759231A EP 02759231 A EP02759231 A EP 02759231A EP 1421097 A4 EP1421097 A4 EP 1421097A4
Authority
EP
European Patent Office
Prior art keywords
biosynthesegencluster
daptomycin
compositions
methods concerning
concerning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02759231A
Other languages
German (de)
French (fr)
Other versions
EP1421097A2 (en
Inventor
Vivian Pak Woon Miao
Paul Brian
Richard H Baltz
Marie Francoise Coeffet-Legal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cubist Pharmaceuticals LLC
Original Assignee
Cubist Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2001/032354 external-priority patent/WO2002059322A2/en
Application filed by Cubist Pharmaceuticals LLC filed Critical Cubist Pharmaceuticals LLC
Publication of EP1421097A2 publication Critical patent/EP1421097A2/en
Publication of EP1421097A4 publication Critical patent/EP1421097A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP02759231A 2001-08-06 2002-07-31 COMPOSITIONS AND METHODS CONCERNING THE DAPTOMYCIN BIOSYNTHESEGENCLUSTER Withdrawn EP1421097A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US31038501P 2001-08-06 2001-08-06
US310385P 2001-08-06
WOPCT/US01/32354 2001-10-17
PCT/US2001/032354 WO2002059322A2 (en) 2000-10-17 2001-10-17 Compositions and methods relating to the daptomycin biosynthetic gene cluster
US37986602P 2002-05-10 2002-05-10
US379866P 2002-05-10
PCT/US2002/024310 WO2003014297A2 (en) 2001-08-06 2002-07-31 Compositions and methods relating to the daptomycin biosynthetic gene cluster

Publications (2)

Publication Number Publication Date
EP1421097A2 EP1421097A2 (en) 2004-05-26
EP1421097A4 true EP1421097A4 (en) 2005-07-06

Family

ID=27359112

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02759231A Withdrawn EP1421097A4 (en) 2001-08-06 2002-07-31 COMPOSITIONS AND METHODS CONCERNING THE DAPTOMYCIN BIOSYNTHESEGENCLUSTER

Country Status (3)

Country Link
EP (1) EP1421097A4 (en)
CA (1) CA2456552A1 (en)
WO (1) WO2003014297A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2587848A1 (en) * 2004-11-12 2006-10-19 Cubist Pharmaceuticals, Inc. Antiinfective lipopeptides
CN101830970B (en) * 2009-03-12 2012-06-27 成都雅途生物技术有限公司 Purification and preparation method of high-purity Daptomycin
CN102260700B (en) * 2010-09-24 2014-03-26 天津大学 Construction method and application of streptomyces roseosporus gene engineering bacteria HP-ORF53-55
CN102206694B (en) * 2011-04-06 2013-10-16 山东新时代药业有限公司 Slow-release composition containing capric acid
JP6741572B2 (en) 2013-03-15 2020-08-19 モジュラー ジェネティクス， インコーポレイテッド Production of acyl amino acids
US11371066B2 (en) 2015-07-13 2022-06-28 Modular Genetics, Inc. Generation of acyl alcohols
CN110408603B (en) * 2019-08-01 2022-09-23 上海交通大学 A54145C1 mutant with altered fatty acyl selectivity and its construction and application
CN113717909B (en) * 2020-05-26 2024-11-05 杭州中美华东制药有限公司 A daptomycin high-yield strain and its application
CN111575251B (en) * 2020-05-29 2022-03-11 上海交通大学 Construction of dptC1 mutant for daptomycin biosynthesis
CN112089823B (en) * 2020-09-25 2024-02-06 珠海中科先进技术研究院有限公司 Composition of aureobasidin A and nystatin and composite ointment, gel and spray thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827689A (en) * 1996-11-13 1998-10-27 Smithkline Beecham Corporation FabD polynucleotides
US6258934B1 (en) * 1997-01-24 2001-07-10 Smithkline Beecham Corporation FabD

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827689A (en) * 1996-11-13 1998-10-27 Smithkline Beecham Corporation FabD polynucleotides
US6258934B1 (en) * 1997-01-24 2001-07-10 Smithkline Beecham Corporation FabD

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 15 October 1997 (1997-10-15), "Streptomyces roseosporus daptomycin biosynthetic protein subunit gene, partial cds.", XP002313744, retrieved from EBI accession no. EM_PRO:AF021262 Database accession no. AF021262 *
MCHENNEY M A ET AL: "Molecular cloning and physical mapping of the daptomycin gene cluster from streptomyces roseosporus", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 180, no. 1, January 1998 (1998-01-01), pages 143 - 151, XP002961809, ISSN: 0021-9193 *
See also references of WO03014297A2 *

Also Published As

Publication number Publication date
WO2003014297A3 (en) 2003-05-22
WO2003014297A2 (en) 2003-02-20
CA2456552A1 (en) 2003-02-20
EP1421097A2 (en) 2004-05-26

Similar Documents

Publication Publication Date Title
ATE368018T1 (en) PLASTER COMPOSITIONS AND ASSOCIATED METHODS
DE60134851D1 (en) HARDENABLE COMPOSITIONS AND COMPATIBILITY AGENTS
DE60206653D1 (en) FLAME RESISTANT RESIN COMPOSITIONS AND METHODS
DE60003250D1 (en) Cleaning compositions and cleaning methods
DE60229770D1 (en) FRICTION-REDUCING COMPOSITION AND METHOD
DE122009000025I1 (en) ANTIBODIES TO IL-12, COMPOSITIONS, PROCESSES AND USES
DE60207627D1 (en) Coating and coating composition
ATE350450T1 (en) DETERGENT COMPOSITIONS AND COMPONENTS THEREOF
DE60140895D1 (en) COMPOSITION AND METHOD
EP1298180A4 (en) HYDROFUGE AND OLEOFUE COMPOSITION
ATE324387T1 (en) CLEAR AND FLEXIBLE POLYPROPENE COMPOSITIONS
FI20010780A0 (en) Improved compositions
AU2002357119A8 (en) Mitocidal compositions and methods
EP1311551A4 (en) BIOACTIVE COATING COMPOSITIONS AND METHOD
IS6915A (en) composition
ATE426657T1 (en) COMPOSITIONS FOR CLEANING AND DISINFECTING HARD SURFACES
DE60233444D1 (en) PARTS ATTACHMENT AND PART-ATTACHING METHOD
DE69918842D1 (en) DISINFECTION COMPOSITIONS AND METHODS
EP1450752A4 (en) MULTIVALENT STREPTOCOCCULAR VACCINE COMPOSITIONS AND APPLICATION METHODS
DE60208700D1 (en) SCHÄLGERÄT AND ASSOCIATED PROCEDURES
EP1455841A4 (en) OSTEOPONTIN-RELATED COMPOSITIONS AND METHODS
DE60234410D1 (en) ERROR-EFFECTIVE PROCEDURE
EP1421097A4 (en) COMPOSITIONS AND METHODS CONCERNING THE DAPTOMYCIN BIOSYNTHESEGENCLUSTER
EP1385947A4 (en) COMPOSITIONS AND METHODS FOR BLOOD CONTROL
EP1073333A4 (en) S-RABEPRAZOL COMPOSITIONS AND METHODS

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040305

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12Q 1/68 B

Ipc: 7C 12P 21/06 B

Ipc: 7C 12N 5/02 B

Ipc: 7C 12N 5/00 B

Ipc: 7C 12N 1/16 B

Ipc: 7C 12N 1/14 B

Ipc: 7C 12N 1/20 B

Ipc: 7C 12N 15/74 B

Ipc: 7C 07H 21/04 A

A4 Supplementary search report drawn up and despatched

Effective date: 20050513

17Q First examination report despatched

Effective date: 20050729

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20100429