EP1424390A4 - Intakter hepatitis-c-virus und verfahren zu seiner kultivierung in einer in-vitro-zellkultur - Google Patents
Intakter hepatitis-c-virus und verfahren zu seiner kultivierung in einer in-vitro-zellkulturInfo
- Publication number
- EP1424390A4 EP1424390A4 EP02754159A EP02754159A EP1424390A4 EP 1424390 A4 EP1424390 A4 EP 1424390A4 EP 02754159 A EP02754159 A EP 02754159A EP 02754159 A EP02754159 A EP 02754159A EP 1424390 A4 EP1424390 A4 EP 1424390A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- virus
- hcv
- culturing
- cell culture
- hepatitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000012258 culturing Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 241000711549 Hepacivirus C Species 0.000 title 1
- 238000004113 cell culture Methods 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 101800001014 Non-structural protein 5A Proteins 0.000 abstract 1
- 101800001554 RNA-directed RNA polymerase Proteins 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000001524 infective effect Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24251—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01124001 | 2001-08-06 | ||
| CN01124001A CN1093172C (zh) | 2001-03-19 | 2001-08-06 | 丙型肝炎全病毒及其体外细胞培养方法 |
| PCT/CN2002/000536 WO2003040356A1 (en) | 2001-08-06 | 2002-08-05 | The intact hepatitis c virus and the method for culturing it in a vitro cell culture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1424390A1 EP1424390A1 (de) | 2004-06-02 |
| EP1424390A4 true EP1424390A4 (de) | 2004-12-15 |
Family
ID=4665429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP02754159A Withdrawn EP1424390A4 (de) | 2001-08-06 | 2002-08-05 | Intakter hepatitis-c-virus und verfahren zu seiner kultivierung in einer in-vitro-zellkultur |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20040166488A1 (de) |
| EP (1) | EP1424390A4 (de) |
| WO (1) | WO2003040356A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2482846B1 (de) | 2009-10-02 | 2016-06-29 | Hvidovre Hospital | Infektiöse hepatitis c viren des genotyps 3a und 4a und deren verwendung |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991015573A1 (en) * | 1990-04-03 | 1991-10-17 | Southwest Foundation For Biomedical Research | An immortalized primate hepatocyte cell line |
| US6127116A (en) * | 1995-08-29 | 2000-10-03 | Washington University | Functional DNA clone for hepatitis C virus (HCV) and uses thereof |
| US6225048B1 (en) * | 1997-10-01 | 2001-05-01 | Oregon Health Sciences University | Dendritic-marker expressing macrophage cultures and methods of reactivating latent virus |
-
2002
- 2002-08-05 WO PCT/CN2002/000536 patent/WO2003040356A1/zh not_active Ceased
- 2002-08-05 US US10/486,024 patent/US20040166488A1/en not_active Abandoned
- 2002-08-05 EP EP02754159A patent/EP1424390A4/de not_active Withdrawn
Non-Patent Citations (4)
| Title |
|---|
| DASH S ET AL: "TRANSFECTION OF HEPG2 CELLS WITH INFECTIOUS HEPATITIS C VIRUS GENOME", AMERICAN JOURNAL OF PATHOLOGY, PHILADELPHIA, PA, US, vol. 151, no. 2, August 1997 (1997-08-01), pages 363 - 373, XP001029512, ISSN: 0002-9440 * |
| DATABASE PROTEIN XP002296369, retrieved from NCBI Database accession no. AAA86907 * |
| LOHMANN V ET AL: "MULTATION IN HEPATITIS C VIRUS RNAS CONFERRING CELL CULTURE ADAPTATION", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 75, no. 3, February 2001 (2001-02-01), pages 1437 - 1449, XP001029115, ISSN: 0022-538X * |
| See also references of WO03040356A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003040356A1 (en) | 2003-05-15 |
| EP1424390A1 (de) | 2004-06-02 |
| US20040166488A1 (en) | 2004-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20040304 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 61K 38/00 B Ipc: 7A 61K 39/29 B Ipc: 7C 07K 14/18 B Ipc: 7C 12N 7/01 A |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20041029 |
|
| 17Q | First examination report despatched |
Effective date: 20050602 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20070301 |