EP1443951A4 - Molecular interactions in cells - Google Patents
Molecular interactions in cellsInfo
- Publication number
- EP1443951A4 EP1443951A4 EP02756934A EP02756934A EP1443951A4 EP 1443951 A4 EP1443951 A4 EP 1443951A4 EP 02756934 A EP02756934 A EP 02756934A EP 02756934 A EP02756934 A EP 02756934A EP 1443951 A4 EP1443951 A4 EP 1443951A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cells
- molecular interactions
- interactions
- molecular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000004001 molecular interaction Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30984101P | 2001-08-03 | 2001-08-03 | |
| US309841P | 2001-08-03 | ||
| US36006102P | 2002-02-25 | 2002-02-25 | |
| US360061P | 2002-02-25 | ||
| PCT/US2002/024655 WO2003014303A2 (en) | 2001-08-03 | 2002-08-02 | Molecular interactions in cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1443951A2 EP1443951A2 (en) | 2004-08-11 |
| EP1443951A4 true EP1443951A4 (en) | 2006-05-03 |
Family
ID=26977039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP02756934A Withdrawn EP1443951A4 (en) | 2001-08-03 | 2002-08-02 | Molecular interactions in cells |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1443951A4 (en) |
| AU (1) | AU2002321903A1 (en) |
| CA (1) | CA2457424A1 (en) |
| WO (1) | WO2003014303A2 (en) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6942981B1 (en) | 1999-05-14 | 2005-09-13 | Arbor Vita Corporation | Method of determining interactions with PDZ-domain polypeptides |
| EP1531842A4 (en) | 2000-12-22 | 2007-03-07 | Dana Farber Cancer Inst Inc | REGULATION OF CELL PROLIFERATION BY MUC1 |
| AU2003291558B2 (en) * | 2001-08-03 | 2009-08-13 | Arbor Vita Corporation | Molecular interactions in neurons |
| WO2004045535A2 (en) * | 2002-11-14 | 2004-06-03 | Arbor Vita Corporation | Molecular interactions in neurons |
| DE10254601A1 (en) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Gene products differentially expressed in tumors and their use |
| EP1599214A4 (en) * | 2003-02-27 | 2006-06-21 | Arbor Vita Corp | METHODS AND COMPOSITIONS FOR TREATING UTERINE COLON CANCER |
| EP1622598A2 (en) * | 2003-05-02 | 2006-02-08 | Scottish Biomedical Limited | Regulation of guanine nucleotide exchange factor |
| WO2004108142A2 (en) * | 2003-06-06 | 2004-12-16 | The University Of Manchester | Inhibitors of tip-1 for treatment tissue damage |
| EP1651671A2 (en) | 2003-07-30 | 2006-05-03 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Epha2 t-cell epitope agonists and uses therefor |
| WO2005042573A1 (en) | 2003-10-24 | 2005-05-12 | Dana-Farber Cancer Institute, Inc. | Modulation of the interaction of muc1 with muc1 ligands |
| WO2005063286A1 (en) | 2003-12-23 | 2005-07-14 | Arbor Vita Corporation | Antibodies for oncogenic strains of hpv and methods of their use |
| EP1709084A4 (en) * | 2003-12-23 | 2008-05-28 | Nono Inc | Polypeptides for modulating binding of trp channel proteins and trp-associated proteins |
| DE102004024617A1 (en) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentially expressed in tumors gene products and their use |
| AU2005319578A1 (en) * | 2004-11-24 | 2006-06-29 | Neopro Labs, Llc | Methods and compositions for treating conditions |
| SG158153A1 (en) * | 2004-12-21 | 2010-01-29 | Musc Found For Res Dev | Compositions and methods for promoting wound healing and tissue regeneration |
| US9408381B2 (en) | 2004-12-21 | 2016-08-09 | Musc Foundation For Research Development | Alpha Connexin c-Terminal (ACT) peptides for use in transplant |
| DE102005022182A1 (en) * | 2005-05-09 | 2006-11-16 | Combinature Biopharm Ag | Modulators of the PDZ domain |
| CA2613749A1 (en) * | 2005-07-01 | 2007-01-11 | Arbor Vita Corporation | Methods and compositions for diagnosis and treatment of viral and bacterial infections |
| EP1790664A1 (en) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer |
| US8633160B2 (en) | 2005-12-30 | 2014-01-21 | Nono Inc. | Small molecule inhibitors of PDZ interactions |
| US7972870B2 (en) | 2007-02-02 | 2011-07-05 | Dana-Farber Cancer Institute, Inc. | Methods and compositions relating to the regulation of MUC1 by HSF1 and STAT3 |
| WO2008097844A2 (en) | 2007-02-02 | 2008-08-14 | Dana -Farber Cancer Institute, Inc. | Methods and compositions relating to the regulation of apoptosis by muc1 and bh3- containing proapoptotic proteins |
| WO2010004003A2 (en) | 2008-07-09 | 2010-01-14 | University Of Copenhagen | Modified peptides as potent inhibitors of the psd-95/nmda receptor interaction |
| CA2866115C (en) | 2012-03-01 | 2020-03-24 | Firststring Research, Inc. | Topical gels containing alpha connexin c-terminal (act) peptides |
| WO2013167153A1 (en) | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
| WO2015017034A1 (en) * | 2013-08-02 | 2015-02-05 | Gourdie Robert G | Methods of treating a cancer through targeted disruption of alpha connexin 43-zonula occludens-1 (zo-1) interaction |
| US20170165317A1 (en) * | 2013-11-26 | 2017-06-15 | Trustees Of Dartmouth College | Method for mitigating or alleviating synaptic and cognitive deficits |
| US10465188B2 (en) | 2014-08-22 | 2019-11-05 | Auckland Uniservices Limited | Channel modulators |
| BR112020000115A2 (en) * | 2017-07-05 | 2020-07-07 | Biocells (Beijing) Biotech Co., Ltd. | pharmaceutically acceptable salts of polypeptides and use thereof |
| JP2023546757A (en) | 2020-10-22 | 2023-11-07 | シークエル・バイオ・インコーポレイテッド | Peptide preparations and their use in ophthalmology |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5976819A (en) * | 1995-11-21 | 1999-11-02 | National Jewish Medical And Research Center | Product and process to regulate actin polymerization in T lymphocytes |
| US6911526B2 (en) * | 1996-07-22 | 2005-06-28 | The Trustees Of Columbia University In The City Of New York | Compounds that inhibit the interaction between signal-transducing proteins and the GLGF (PDZ/DHR) domain and uses thereof |
| AU1254700A (en) * | 1998-11-20 | 2000-06-13 | Mount Sinai Hospital Corporation | Peptides that modulate the interaction of b class ephrins and pdz domains |
| JP2002543825A (en) * | 1999-05-14 | 2002-12-24 | アーバー ビータ コーポレイション | Hematopoietic intracellular molecular interactions |
-
2002
- 2002-08-02 AU AU2002321903A patent/AU2002321903A1/en not_active Abandoned
- 2002-08-02 EP EP02756934A patent/EP1443951A4/en not_active Withdrawn
- 2002-08-02 CA CA002457424A patent/CA2457424A1/en not_active Abandoned
- 2002-08-02 WO PCT/US2002/024655 patent/WO2003014303A2/en not_active Ceased
Non-Patent Citations (1)
| Title |
|---|
| No further relevant documents disclosed * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003014303A3 (en) | 2003-08-14 |
| CA2457424A1 (en) | 2003-02-20 |
| AU2002321903A1 (en) | 2003-02-24 |
| WO2003014303A2 (en) | 2003-02-20 |
| EP1443951A2 (en) | 2004-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20040223 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20060320 |
|
| 17Q | First examination report despatched |
Effective date: 20090327 |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: ARBOR VITA CORPORATION |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20120216 |