EP1446414A4 - GENES EXPRESSED DIFFERENTIALLY, ASSOCIATED WITH OBESITY AND TYPE 2 DIABETES - Google Patents

GENES EXPRESSED DIFFERENTIALLY, ASSOCIATED WITH OBESITY AND TYPE 2 DIABETES

Info

Publication number
EP1446414A4
EP1446414A4 EP02801234A EP02801234A EP1446414A4 EP 1446414 A4 EP1446414 A4 EP 1446414A4 EP 02801234 A EP02801234 A EP 02801234A EP 02801234 A EP02801234 A EP 02801234A EP 1446414 A4 EP1446414 A4 EP 1446414A4
Authority
EP
European Patent Office
Prior art keywords
obesity
diabetes
type
genes expressed
expressed differentially
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02801234A
Other languages
German (de)
French (fr)
Other versions
EP1446414A1 (en
Inventor
Greg Collier
Paul Zev Zimmet
Ken Walder
Janine Mcmillan
Silva Andrea Michelle De
Kelly Windmill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deakin University
International Diabetes Institute
Autogen Research Pty Ltd
Original Assignee
Deakin University
International Diabetes Institute
Autogen Research Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deakin University, International Diabetes Institute, Autogen Research Pty Ltd filed Critical Deakin University
Publication of EP1446414A1 publication Critical patent/EP1446414A1/en
Publication of EP1446414A4 publication Critical patent/EP1446414A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Plant Pathology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
EP02801234A 2001-10-16 2002-10-16 GENES EXPRESSED DIFFERENTIALLY, ASSOCIATED WITH OBESITY AND TYPE 2 DIABETES Withdrawn EP1446414A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33014901P 2001-10-16 2001-10-16
US330149P 2001-10-16
PCT/AU2002/001405 WO2003033513A1 (en) 2001-10-16 2002-10-16 Differentially expressed genes associated with obesity and type 2 diabetes

Publications (2)

Publication Number Publication Date
EP1446414A1 EP1446414A1 (en) 2004-08-18
EP1446414A4 true EP1446414A4 (en) 2005-11-23

Family

ID=23288511

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02801234A Withdrawn EP1446414A4 (en) 2001-10-16 2002-10-16 GENES EXPRESSED DIFFERENTIALLY, ASSOCIATED WITH OBESITY AND TYPE 2 DIABETES

Country Status (9)

Country Link
EP (1) EP1446414A4 (en)
JP (1) JP2005510214A (en)
KR (1) KR20040088019A (en)
CN (1) CN1596264A (en)
CA (1) CA2463578A1 (en)
IL (1) IL161294A0 (en)
MX (1) MXPA04003635A (en)
WO (1) WO2003033513A1 (en)
ZA (1) ZA200402859B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004205064A1 (en) * 2003-01-13 2004-07-29 Autogen Research Pty Ltd Obesity-related genes
DE10352510A1 (en) * 2003-11-07 2005-06-23 Forschungsinstitut Für Die Biologie Landwirtschaftlicher Nutztiere Method for identifying active ingredients for influencing body mass and fat intake
EP1709174B1 (en) 2003-12-24 2012-02-08 Samsung Electronics Co., Ltd Use of a polynucleotide associated with a type ii diabetes mellitus comprising single nucleotide polymorphism, use of a microarray and diagnostic kit comprising the same and method for analyzing polynucleotide using the same
WO2005090378A1 (en) * 2004-03-16 2005-09-29 Agt Biosciences Limited Ligands of the molecule fit (agt-121) and their pharmaceutical use
EP1824518A4 (en) * 2004-12-07 2009-10-28 Univ Ohio DIAGNOSIS OF HYPERINSULINEMA AND TYPE II DIABETES AND PROTECTION AGAINST DIFFERENT EXPRESSED PROTEINS IN THE SERUM
CN115851931A (en) * 2021-06-28 2023-03-28 广东医科大学附属第二医院 Application of a liver cancer molecular marker in the preparation of liver cancer detection or curative effect evaluation products
CN114958875B (en) * 2022-05-15 2023-08-18 赣南师范大学 Screening and application of reference gene metG of citrus yellow-long pathogen

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2780405B1 (en) * 1998-06-25 2001-12-28 Centre Nat Rech Scient NOVEL OLFACTORY RECEPTORS AND USES THEREOF

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
AHIMA R S ET AL: "ROLE OF LEPTIN IN THE NEUROENDOCRINE RESPONSE TO FASTING", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 382, no. 6588, 18 July 1996 (1996-07-18), pages 250 - 252, XP002910922, ISSN: 0028-0836 *
COLLIER G R ET AL: "BEACON. A NOVEL GENE INVOLVED IN THE REGULATION OF ENERGY BALANCE", DIABETES, NEW YORK, NY, US, vol. 49, no. 11, November 2000 (2000-11-01), pages 1766 - 1771, XP008035494, ISSN: 0012-1797 *
DATABASE EMBL 10 March 2001 (2001-03-10), OTTENWAELDER ET AL.: "Homo sapiens mRNA; cDNA DKFZp761D221", XP002346390, Database accession no. AL136561 *
DATABASE EMBL 5 December 2001 (2001-12-05), STRAUSBERG ET AL.: "Mus musculus SH3-domain GRB2-like (endophilin) interacting protein 1, mRNA", XP002346392, Database accession no. BC017596 *
DATABASE Geneseq 18 February 2002 (2002-02-18), DRMANAC ET AL.: "Novel human diagnostic protein #29252.", XP002346391, retrieved from EBI accession no. GSN:ABG29261 Database accession no. ABG29261 *
LIN X ET AL: "DIFFERENTIAL EXPRESSION OF INSULIN RECEPTOR TYROSINE KINASE INHIBITOR (FETUIN) GENE IN A MODEL OF DIET-INDUCED OBESITY", LIFE SCIENCES, PERGAMON PRESS, OXFORD, GB, vol. 63, no. 2, 1998, pages 145 - 153, XP001094792, ISSN: 0024-3205 *
See also references of WO03033513A1 *

Also Published As

Publication number Publication date
CN1596264A (en) 2005-03-16
KR20040088019A (en) 2004-10-15
JP2005510214A (en) 2005-04-21
MXPA04003635A (en) 2004-07-30
WO2003033513A1 (en) 2003-04-24
ZA200402859B (en) 2005-01-24
EP1446414A1 (en) 2004-08-18
CA2463578A1 (en) 2003-04-24
IL161294A0 (en) 2004-09-27

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Extension state: AL LT LV MK RO SI

RIN1 Information on inventor provided before grant (corrected)

Inventor name: WINDMILL, KELLY

Inventor name: DE SILVA, ANDREA, MICHELLE

Inventor name: MCMILLAN, JANINE

Inventor name: WALDER, KEN

Inventor name: ZIMMET, PAUL, ZEV

Inventor name: COLLIER, GREG

A4 Supplementary search report drawn up and despatched

Effective date: 20051007

17Q First examination report despatched

Effective date: 20061128

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20081024