EP1513404A4 - Intramyocardial injection of autologous bone marrow - Google Patents

Intramyocardial injection of autologous bone marrow

Info

Publication number: EP1513404A4
Authority: EP; European Patent Office
Prior art keywords: bone marrow; autologous bone; intramyocardial injection; intramyocardial; injection
Prior art date: 2002-05-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP03756182A

Other languages

German (de)

French (fr)

Other versions

EP1513404A1 (en

Inventor

Stephen Epstein

Shmuel Fuchs

Ran Kornowski

Martin B Leon

Kenneth W Carpenter

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Myocardial Therapeutics Inc

Original Assignee

Myocardial Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-30

Filing date

2003-05-16

Publication date

2006-01-04

2003-05-16 Application filed by Myocardial Therapeutics Inc filed Critical Myocardial Therapeutics Inc

2005-03-16 Publication of EP1513404A1 publication Critical patent/EP1513404A1/en

2006-01-04 Publication of EP1513404A4 publication Critical patent/EP1513404A4/en

Status Withdrawn legal-status Critical Current

Links

210000001185 bone marrow Anatomy 0.000 title 1
238000002347 injection Methods 0.000 title 1
239000007924 injection Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Public Health (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Toxicology (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Materials For Medical Uses (AREA)

EP03756182A 2002-05-30 2003-05-16 Intramyocardial injection of autologous bone marrow Withdrawn EP1513404A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US160514		1998-09-24
US16051402A	2002-05-30	2002-05-30
PCT/US2003/015529 WO2003101201A1 (en)	2002-05-30	2003-05-16	Intramyocardial injection of autologous bone marrow

Publications (2)

Publication Number	Publication Date
EP1513404A1 EP1513404A1 (en)	2005-03-16
EP1513404A4 true EP1513404A4 (en)	2006-01-04

Family

ID=29709714

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP03756182A Withdrawn EP1513404A4 (en)	2002-05-30	2003-05-16	Intramyocardial injection of autologous bone marrow

Country Status (5)

Country	Link
EP (1)	EP1513404A4 (en)
JP (1)	JP4111950B2 (en)
AU (1)	AU2003232152A1 (en)
CA (1)	CA2487410C (en)
WO (1)	WO2003101201A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH086437A (en) *	1994-06-17	1996-01-12	Nec Corp	Photosensitive drum driving gear of electrophotographic device
AU2005209845A1 (en) *	2004-01-30	2005-08-18	Chemgenex Pharmaceuticals, Inc.	Naphthalimide dosing by N-acetyl transferase genotyping
US20130078224A1 (en)	2010-03-30	2013-03-28	Life Sciences Research Partners Vzw	Induction/monitoring of arteriogenesis using sdf1 and pdgfb or inhibition of phd2
EP3097928A1 (en) *	2015-05-28	2016-11-30	Organes Tissus Régénération Réparation Remplacement	Composition for the treatment of brain lesions
EP3097922A1 (en)	2015-05-28	2016-11-30	Denis Barritault	Composition for the treatment of tissue lesions
US10881692B2 (en)	2018-04-05	2021-01-05	Medeor Therapeutics, Inc.	Compositions for establishing mixed chimerism and methods of manufacture thereof
US10842821B2 (en)	2018-04-05	2020-11-24	Medeor Therapeutics, Inc.	Cellular compositions derived from prior organ donors and methods of manufacture and use thereof
US11813376B2 (en)	2018-09-18	2023-11-14	Medeor Therapeutics, Inc.	Cellular compositions derived from deceased donors to promote graft tolerance and manufacture and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6013780A (en) *	1996-09-06	2000-01-11	Technion Research & Development Co. Ltd.	VEGF145 expression vectors
CA2368677C (en) *	1999-03-30	2012-07-10	Ran Kornowski	Intramyocardial injection of autologous bone marrow

2003
- 2003-05-16 CA CA2487410A patent/CA2487410C/en not_active Expired - Lifetime
- 2003-05-16 JP JP2004508572A patent/JP4111950B2/en not_active Expired - Lifetime
- 2003-05-16 EP EP03756182A patent/EP1513404A4/en not_active Withdrawn
- 2003-05-16 AU AU2003232152A patent/AU2003232152A1/en not_active Abandoned
- 2003-05-16 WO PCT/US2003/015529 patent/WO2003101201A1/en not_active Ceased

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ASAHARA T ET AL.: "Gene therapy of endothelial progenitor cell for vascular development in severe ischemic disease", CIRCULATION, vol. 100, 1999, pages I-481, XP009051610 *
ISNER JEFFREY M: "Myocardial gene therapy", NATURE (LONDON), vol. 415, no. 6868, 10 January 2002 (2002-01-10), pages 234 - 239, XP002340057, ISSN: 0028-0836 *
See also references of WO03101201A1 *

Also Published As

Publication number	Publication date
CA2487410C (en)	2015-03-24
AU2003232152A1 (en)	2003-12-19
JP2005527228A (en)	2005-09-15
EP1513404A1 (en)	2005-03-16
CA2487410A1 (en)	2003-12-11
JP4111950B2 (en)	2008-07-02
WO2003101201A1 (en)	2003-12-11

Legal Events

Date	Code	Title	Description
2005-01-28	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2005-03-16	17P	Request for examination filed	Effective date: 20041221
2005-03-16	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
2006-01-04	A4	Supplementary search report drawn up and despatched	Effective date: 20051116
2006-12-06	RIN1	Information on inventor provided before grant (corrected)	Inventor name: EPSTEIN, STEPHEN Inventor name: CARPENTER, KENNETH, W. Inventor name: LEON, MARTIN B. Inventor name: KORNOWSKI, RAN Inventor name: FUCHS, SHMUEL
2006-12-27	RIN1	Information on inventor provided before grant (corrected)	Inventor name: FUCHS, SHMUEL Inventor name: EPSTEIN, STEPHEN Inventor name: KORNOWSKI, RAN Inventor name: CARPENTER, KENNETH, W. Inventor name: LEON, MARTIN B.
2009-04-24	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2009-05-27	18D	Application deemed to be withdrawn	Effective date: 20081202

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