EP1723958A3 - Dsrna vektorisierung mittels kationischen partikeln und ihre topische anwendung - Google Patents

Dsrna vektorisierung mittels kationischen partikeln und ihre topische anwendung Download PDF

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Publication number
EP1723958A3
EP1723958A3 EP06290795A EP06290795A EP1723958A3 EP 1723958 A3 EP1723958 A3 EP 1723958A3 EP 06290795 A EP06290795 A EP 06290795A EP 06290795 A EP06290795 A EP 06290795A EP 1723958 A3 EP1723958 A3 EP 1723958A3
Authority
EP
European Patent Office
Prior art keywords
cationic
dsrna
vectorisation
topical use
cationic particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP06290795A
Other languages
English (en)
French (fr)
Other versions
EP1723958B1 (de
EP1723958A2 (de
Inventor
Christine Collin-Djangone
Jean-Thierry Simonnet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Publication of EP1723958A2 publication Critical patent/EP1723958A2/de
Publication of EP1723958A3 publication Critical patent/EP1723958A3/de
Application granted granted Critical
Publication of EP1723958B1 publication Critical patent/EP1723958B1/de
Anticipated expiration legal-status Critical
Not-in-force legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/606—Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0291—Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP06290795.1A 2005-05-19 2006-05-16 Doppelsträngige-RNA Vektorisierung mittels kationischen Partikeln und ihre topische Anwendung Not-in-force EP1723958B1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0551301A FR2885808B1 (fr) 2005-05-19 2005-05-19 Vectorisation de dsrna par des particules cationiques et utilisation topique.

Publications (3)

Publication Number Publication Date
EP1723958A2 EP1723958A2 (de) 2006-11-22
EP1723958A3 true EP1723958A3 (de) 2006-12-06
EP1723958B1 EP1723958B1 (de) 2013-06-26

Family

ID=35466111

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06290795.1A Not-in-force EP1723958B1 (de) 2005-05-19 2006-05-16 Doppelsträngige-RNA Vektorisierung mittels kationischen Partikeln und ihre topische Anwendung

Country Status (5)

Country Link
EP (1) EP1723958B1 (de)
JP (1) JP5254535B2 (de)
CA (1) CA2547122A1 (de)
ES (1) ES2426939T3 (de)
FR (1) FR2885808B1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010002969A1 (de) * 2010-03-17 2011-11-17 Rovi Cosmetics International Gmbh Zusammensetzung mit einem Sirtuin-Aktivator
ITTO20110527A1 (it) 2011-06-15 2012-12-16 Bruno Massimo Cetroni Apparecchio per trattamenti terapeutici con onde elettromagnetiche risonanti pulsate
FR3043695B1 (fr) * 2015-11-17 2019-10-25 ISP Investments LLC. Procede d'obtention d'un extrait aqueux enrichi en petits arn a partir d'une matiere vegetal et extraits issus du procede
IL316195A (en) 2017-12-15 2024-12-01 Flagship Pioneering Innovations Vi Llc Preparations containing circular polyribonucleotides and uses thereof
MA55083A (fr) * 2019-03-01 2022-03-16 Flagship Pioneering Innovations Vi Llc Polyribonucléotides et leurs utilisations cosmétiques
CN113661242A (zh) 2019-03-25 2021-11-16 旗舰创业创新第六有限责任公司 包含经修饰的环状多核糖核苷酸的组合物及其用途
FR3106754B1 (fr) 2020-02-04 2022-01-07 Isp Investments Llc Procede d’obtention d’un extrait aqueux de lavande, compositions comprenant un tel extrait et leurs utilisations cosmetiques
FR3116438B1 (fr) 2020-11-23 2022-10-14 Isp Investments Llc Procede d’obtention d’extraits aqueux de feuilles de thes, compositions comprenant de tels extraits et leurs utilisations cosmetiques
FR3125425B1 (fr) 2021-07-22 2024-09-13 Isp Investments Llc Extrait de feuilles de the noir, compositions le comprenant et ses utilisations cosmetiques

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003101376A2 (fr) * 2002-06-03 2003-12-11 L'oreal Utilisation par voie topique d'au moins un oligonucleotide d'arn double brin (ds rna)
WO2003106636A2 (en) * 2002-06-14 2003-12-24 Mirus Corporation Novel methods for the delivery of polynucleotides to cells
WO2004046354A1 (de) * 2002-11-20 2004-06-03 Beiersdorf Ag Oligoribonukleotide zur behandlung von degenerativen hauterscheinungen durch rna-interferenz

Family Cites Families (25)

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FR2315991A1 (fr) * 1975-06-30 1977-01-28 Oreal Procede de fabrication de dispersions aqueuses de spherules lipidiques et nouvelles compositions correspondantes
GB1567947A (en) 1976-07-02 1980-05-21 Unilever Ltd Esters of quaternised amino-alcohols for treating fabrics
FR2485921A1 (fr) * 1980-07-01 1982-01-08 Oreal Composition cosmetique a base d'une dispersion aqueuse de spherules lipidiques
DE3623215A1 (de) 1986-07-10 1988-01-21 Henkel Kgaa Neue quartaere ammoniumverbindungen und deren verwendung
IE66830B1 (en) * 1987-08-12 1996-02-07 Hem Res Inc Topically active compositions of double-stranded RNAs
FR2694884B1 (fr) * 1992-08-03 1996-10-18 Oreal Composition formee d'une dispersion aqueuse de vesicules de lipides amphiphiles non-ioniques stabilisees.
FR2725369B1 (fr) 1994-10-07 1997-01-03 Oreal Composition cosmetique ou dermatologique constituee d'une emulsion huile dans eau a base de globules huileux pourvus d'un enrobage cristal liquide lamellaire
FR2730932B1 (fr) 1995-02-27 1997-04-04 Oreal Nanoemulsion transparente a base de lipides amphiphiles non-ioniques fluides et utilisation en cosmetique ou en dermopharmacie
DE19509079A1 (de) 1995-03-15 1996-09-19 Beiersdorf Ag Kosmetische oder dermatologische Mikroemulsionen
FR2760970B1 (fr) 1997-03-18 2000-03-10 Oreal Nanoemulsions a base de lipides amphiphiles non-ioniques et de silicones aminees et utilisations
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
FR2787026B1 (fr) 1998-12-14 2001-01-12 Oreal Nanoemulsion a base d'esters mixtes d'acide gras ou d'alcool gras, d'acide carboxylique et de glyceryle, et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
FR2787027B1 (fr) 1998-12-14 2001-01-12 Oreal Nanoemulsion a base d'esters gras de sucre ou d'ethers gras de sucre et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
FR2787326B1 (fr) 1998-12-17 2001-01-26 Oreal Nanoemulsion a base d'esters gras de glycerol, et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
FR2787728B1 (fr) 1998-12-23 2001-01-26 Oreal Nanoemulsion a base d'esters gras d'acide phosphorique, et ses utilisations dans les domaines cosmetique, dermatologique, pharmaceutique et/ou ophtalmologique
FR2787703B1 (fr) 1998-12-29 2001-01-26 Oreal Nanoemulsion a base d'ethers gras ethoxyles ou d'esters gras ethoxyles, et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
FR2788007B1 (fr) 1999-01-05 2001-02-09 Oreal Nanoemulsion a base de copolymeres blocs d'oxyde d'ethylene et d'oxyde de propylene, et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
EP2314700A1 (de) 1999-01-28 2011-04-27 Medical College of Georgia Research Institute, Inc Zusammensetzung und Verfahren zur in vivo und in vitro Abschwächung der Genexpression mittels dobbelsträngiger RNA
DE19956568A1 (de) 1999-01-30 2000-08-17 Roland Kreutzer Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
FR2788980B1 (fr) 1999-02-02 2002-04-12 Oreal Nanoemulsion a base d'alkenyl succinates alkoxyles ou d'alkenyl succinates de glucose alkoxyles, et ses utilisations dans les domaines cosmetique, dermatologique, ophtalmologique et/ou pharmaceutique
CA2386270A1 (en) 1999-10-15 2001-04-26 University Of Massachusetts Rna interference pathway genes as tools for targeted genetic interference
GB9927444D0 (en) 1999-11-19 2000-01-19 Cancer Res Campaign Tech Inhibiting gene expression
FR2804015B1 (fr) 2000-01-21 2005-12-23 Oreal Nanoemulsion contenant des lipides amphiphiles et un polymere non ionique et utilisations
EP2213737B1 (de) 2002-02-01 2012-11-07 Life Technologies Corporation Doppelsträngige Oligonukleotide
WO2004035013A2 (en) 2002-10-21 2004-04-29 L'oreal Process for dissolving lipophilic compounds, and cosmetic composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003101376A2 (fr) * 2002-06-03 2003-12-11 L'oreal Utilisation par voie topique d'au moins un oligonucleotide d'arn double brin (ds rna)
WO2003106636A2 (en) * 2002-06-14 2003-12-24 Mirus Corporation Novel methods for the delivery of polynucleotides to cells
WO2004046354A1 (de) * 2002-11-20 2004-06-03 Beiersdorf Ag Oligoribonukleotide zur behandlung von degenerativen hauterscheinungen durch rna-interferenz

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
STEIN C A ET AL: "A critical assessment of the potential of short interfering RNA therapeutics", DRUG DISCOVERY TODAY: TECHNOLOGIES, ELSEVIER, vol. 2, no. 1, April 2005 (2005-04-01), pages 27 - 31, XP004985725, ISSN: 1740-6749 *

Also Published As

Publication number Publication date
FR2885808A1 (fr) 2006-11-24
FR2885808B1 (fr) 2007-07-06
EP1723958B1 (de) 2013-06-26
EP1723958A2 (de) 2006-11-22
JP2006321801A (ja) 2006-11-30
CA2547122A1 (fr) 2006-11-19
ES2426939T3 (es) 2013-10-25
JP5254535B2 (ja) 2013-08-07

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