EP1861509A4 - METHOD OF PREDICTING SURVIVAL WITHOUT PROGRESSION AND GLOBAL SURVIVAL, EVERYWHERE OF FOLLOW-UP, DURING THE TREATMENT OF PATIENTS WITH METASTATIC BREAST CANCER USING CIRCULATING TUMOR CELLS - Google Patents
METHOD OF PREDICTING SURVIVAL WITHOUT PROGRESSION AND GLOBAL SURVIVAL, EVERYWHERE OF FOLLOW-UP, DURING THE TREATMENT OF PATIENTS WITH METASTATIC BREAST CANCER USING CIRCULATING TUMOR CELLSInfo
- Publication number
- EP1861509A4 EP1861509A4 EP20050725638 EP05725638A EP1861509A4 EP 1861509 A4 EP1861509 A4 EP 1861509A4 EP 20050725638 EP20050725638 EP 20050725638 EP 05725638 A EP05725638 A EP 05725638A EP 1861509 A4 EP1861509 A4 EP 1861509A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- survival
- everywhere
- progression
- patients
- follow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL05725638T PL1861509T3 (en) | 2005-03-14 | 2005-03-14 | A method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2005/008602 WO2006104474A2 (en) | 2005-03-14 | 2005-03-14 | A method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP1861509A2 EP1861509A2 (en) | 2007-12-05 |
| EP1861509A4 true EP1861509A4 (en) | 2010-04-14 |
| EP1861509B1 EP1861509B1 (en) | 2015-09-09 |
Family
ID=37053815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP05725638.0A Expired - Lifetime EP1861509B1 (en) | 2005-03-14 | 2005-03-14 | A method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1861509B1 (en) |
| JP (1) | JP2008533487A (en) |
| CA (1) | CA2600225C (en) |
| DK (1) | DK1861509T3 (en) |
| PL (1) | PL1861509T3 (en) |
| WO (1) | WO2006104474A2 (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITBO20040420A1 (en) | 2004-07-07 | 2004-10-07 | Type S R L | METAL CUTTING AND FORMING MACHINE |
| ITBO20050481A1 (en) | 2005-07-19 | 2007-01-20 | Silicon Biosystems S R L | METHOD AND APPARATUS FOR THE HANDLING AND / OR IDENTIFICATION OF PARTICLES |
| US7993821B2 (en) | 2005-08-11 | 2011-08-09 | University Of Washington | Methods and apparatus for the isolation and enrichment of circulating tumor cells |
| US8173413B2 (en) | 2005-08-11 | 2012-05-08 | University Of Washington | Separation and concentration of biological cells and biological particles using a one-dimensional channel |
| ITBO20050646A1 (en) | 2005-10-26 | 2007-04-27 | Silicon Biosystem S R L | METHOD AND APPARATUS FOR CHARACTERIZATION AND COUNTING OF PARTICLES |
| ITTO20060226A1 (en) | 2006-03-27 | 2007-09-28 | Silicon Biosystem S P A | METHOD AND APPARATUS FOR PROCESSING AND OR ANALYSIS AND OR SELECTION OF PARTICLES, IN PARTICULAR BIOLOGICAL PARTICLES |
| MX2008015425A (en) | 2006-06-02 | 2008-12-12 | Pfizer Prod Inc | Circulating tumor cell assay. |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| EP2589668A1 (en) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
| US8841135B2 (en) | 2007-06-20 | 2014-09-23 | University Of Washington | Biochip for high-throughput screening of circulating tumor cells |
| ITTO20070771A1 (en) | 2007-10-29 | 2009-04-30 | Silicon Biosystems Spa | METHOD AND APPARATUS FOR IDENTIFICATION AND HANDLING OF PARTICLES |
| US8071395B2 (en) | 2007-12-12 | 2011-12-06 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and apparatus for magnetic separation of cells |
| US10895575B2 (en) | 2008-11-04 | 2021-01-19 | Menarini Silicon Biosystems S.P.A. | Method for identification, selection and analysis of tumour cells |
| IT1391619B1 (en) | 2008-11-04 | 2012-01-11 | Silicon Biosystems Spa | METHOD FOR THE IDENTIFICATION, SELECTION AND ANALYSIS OF TUMOR CELLS |
| CA2782123C (en) | 2009-03-17 | 2017-05-02 | Silicon Biosystems S.P.A. | Microfluidic device for isolation of cells |
| JP6017845B2 (en) * | 2011-06-10 | 2016-11-02 | 帝人ファーマ株式会社 | Method for detecting cells lacking GPI anchor protein |
| ITTO20110990A1 (en) | 2011-10-28 | 2013-04-29 | Silicon Biosystems Spa | METHOD AND APPARATUS FOR OPTICAL ANALYSIS OF LOW TEMPERATURE PARTICLES |
| ITBO20110766A1 (en) | 2011-12-28 | 2013-06-29 | Silicon Biosystems Spa | DEVICES, EQUIPMENT, KITS AND METHOD FOR THE TREATMENT OF A BIOLOGICAL SAMPLE |
| RU2547561C1 (en) * | 2013-12-18 | 2015-04-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ульяновский государственный университет" | Method for predicting five-year survival rate in patients with infiltrating breast cancer by determining total score of malignancy |
| US11371982B2 (en) | 2016-01-19 | 2022-06-28 | Tosoh Corporation | Method of predicting patient prognosis using rare cells |
| JP7326764B2 (en) | 2018-03-09 | 2023-08-16 | 東ソー株式会社 | Tumor markers and methods for recovering and detecting tumor cells distinct from contaminant cells |
| JP2019158777A (en) * | 2018-03-16 | 2019-09-19 | 東ソー株式会社 | Tumor marker and method for collecting and detecting tumor cell by distinguishing it from contaminant cell |
| JP7521750B2 (en) * | 2020-01-14 | 2024-07-24 | 学校法人杏林学園 | Methods for detecting epithelial marker-negative tumor cells |
| BR112022015011A2 (en) | 2020-01-29 | 2022-09-20 | Corcept Therapeutics Inc | METHOD TO TREAT A SUBJECT SUFFERING FROM ADRENOCORTICAL CARCINOMA TUMOR AND HAVING EXCESS OF CORTISOL, AND, PHARMACEUTICAL COMPOSITION TO TREAT ADRENOCORTICAL CARCINOMA |
| JP7593584B2 (en) * | 2020-03-10 | 2024-12-03 | 学校法人杏林学園 | Tumor cell markers and methods for detecting or harvesting tumor cells - Patents.com |
| AU2021336112A1 (en) * | 2020-09-02 | 2023-05-04 | Menarini Silicon Biosystems S.P.A. | System, kit, method and process for handling a sample |
| CN113284612B (en) * | 2021-05-21 | 2024-04-16 | 大连海事大学 | A survival analysis method based on XGBoost algorithm |
| WO2023180465A1 (en) * | 2022-03-23 | 2023-09-28 | University Of Twente | A magnetic micro-needle to isolate single immunomagnetically labeled cells |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5993388A (en) * | 1997-07-01 | 1999-11-30 | Kattan; Michael W. | Nomograms to aid in the treatment of prostatic cancer |
| WO1999041613A1 (en) * | 1998-02-12 | 1999-08-19 | Immunivest | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| AU2876900A (en) * | 1999-02-10 | 2000-08-29 | Cell Works Inc. | Class characterization of circulating cancer cells isolated from body fluids andmethods of use |
| EP1425294B2 (en) * | 2001-08-23 | 2012-12-12 | Veridex, LLC | Analysis of circulating tumor cells, fragments, and debris |
| AU2003242815A1 (en) * | 2002-03-13 | 2003-09-22 | Biomerieux | Method for the characterisation of circulating tumour cells stemming from solid cancers |
| EP1597353B1 (en) * | 2003-02-27 | 2010-11-24 | Veridex, LLC | CIRCULATING TUMOR CELLS (CTC's): EARLY ASSESSMENT OF TIME TO PROGRESSION SURVIVAL AND RESPONSE TO THERAPY IN METASTATIC CANCER PATIENTS |
-
2005
- 2005-03-14 CA CA2600225A patent/CA2600225C/en not_active Expired - Lifetime
- 2005-03-14 PL PL05725638T patent/PL1861509T3/en unknown
- 2005-03-14 EP EP05725638.0A patent/EP1861509B1/en not_active Expired - Lifetime
- 2005-03-14 JP JP2008501850A patent/JP2008533487A/en active Pending
- 2005-03-14 WO PCT/US2005/008602 patent/WO2006104474A2/en not_active Ceased
- 2005-03-14 DK DK05725638.0T patent/DK1861509T3/en active
Non-Patent Citations (3)
| Title |
|---|
| CRISTOFANILLI MASSIMO ET AL: "Circulating tumor cells, disease progression, and survival in metastatic breast cancer", NEW ENGLAND JOURNAL OF MEDICINE, vol. 351, no. 8, 19 August 2004 (2004-08-19), pages 781 - 791, XP002570580, ISSN: 0028-4793 * |
| CRISTOFANILLI MASSIMO ET AL: "Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer.", JOURNAL OF CLINICAL ONCOLOGY : OFFICIAL JOURNAL OF THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY 1 MAR 2005, vol. 23, no. 7, 1 March 2005 (2005-03-01), pages 1420 - 1430, XP002570579, ISSN: 0732-183X * |
| See also references of WO2006104474A2 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2600225A1 (en) | 2006-10-05 |
| WO2006104474A3 (en) | 2007-02-22 |
| EP1861509A2 (en) | 2007-12-05 |
| CA2600225C (en) | 2016-06-28 |
| WO2006104474A2 (en) | 2006-10-05 |
| JP2008533487A (en) | 2008-08-21 |
| EP1861509B1 (en) | 2015-09-09 |
| PL1861509T3 (en) | 2016-01-29 |
| DK1861509T3 (en) | 2015-12-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1861509A4 (en) | METHOD OF PREDICTING SURVIVAL WITHOUT PROGRESSION AND GLOBAL SURVIVAL, EVERYWHERE OF FOLLOW-UP, DURING THE TREATMENT OF PATIENTS WITH METASTATIC BREAST CANCER USING CIRCULATING TUMOR CELLS | |
| DE602005007623D1 (en) | DISORDERSIZED PYRAZOLOBENZODIAZEPINES SUITABLE AS CDK2 AND ANGIOGENESIS INHIBITORS AND FOR THE TREATMENT OF BREAST, COLON, LUNG AND PROSTATE CANCER | |
| PL2100618T3 (en) | Anti-PDGFR alpha antibody for use in the treatment of metastatic bone cancer | |
| EA200801853A1 (en) | EFFECTIVE PEPTIDES IN THE TREATMENT OF TUMORS AND OTHER DISEASES THAT REQUIRE REMOVAL OR DESTRUCTION OF CELLS | |
| WO2010059969A8 (en) | Use of anti-vegf antibody in combination with chemotherapy for treating breast cancer | |
| NO2017019I2 (en) | Enzalutamide or a pharmaceutically acceptable salt thereof | |
| DK1706112T3 (en) | METHODS OF TREATING AN INFLAMMATOR-RELATED DISEASE | |
| TNSN05300A1 (en) | Treatment with anti-vegf antibodies | |
| PL2894162T3 (en) | Identification of cancer-related antigens for diagnosis and treatment | |
| BRPI0719202A2 (en) | Diagnosis and treatment of cancer using antiereg antibody | |
| CL2008001234A1 (en) | COMPOUNDS DERIVED FROM NITROGEN HETEROCICLES, INHIBITORS OF APOPTOSIS PROTEINS; AND USE IN THE TREATMENT OF CANCER. | |
| BRPI0813364A2 (en) | DIAGNOSTIC METHODS AND CANCER TREATMENT. | |
| NL1025873A1 (en) | Dosage forms and methods of treatment with vegfr inhibitors. | |
| EP1788050A4 (en) | AQUEOUS PRIMARY COMPOSITION, SURFACE TREATMENT METHOD USING THE SAME, AND MULTILAYER STRUCTURE | |
| EP3818171A4 (en) | METHODS FOR DETECTING POPULATIONS OF CELLS ASSOCIATED WITH CANCER, SCREENING FOR METASTATIC CANCER AND RELATED TREATMENTS | |
| WO2006133325A3 (en) | Analysis of tissue samples surrounding malignancies | |
| EP1756166A4 (en) | DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | |
| GB0512299D0 (en) | Diagnosis prognosis and prediction of recurrence of breast cancer | |
| EP1987165A4 (en) | GENES ACTING ON THE PERFORMANCES OF HUMAN MEMORY | |
| PH12012500296A1 (en) | Anti-angiogenesis therapy for the treatment of previously treated breast cancer | |
| IS8497A (en) | Methods and reagents for the treatment of inflammatory diseases | |
| EP1805519A4 (en) | WNT PROTEINS AND DETECTION AND TREATMENT OF CANCER | |
| CY1117701T1 (en) | TEMSIRIOLIMUM ACTIVITY AGAINST TUMOR CANCER CELL RADICAL CELLS | |
| WO2007038264A3 (en) | Gapr-1 methods | |
| EP1474531A4 (en) | ELECTROPHORETIC ANALYSIS FOR PREDICTING THE RISK OF CANCER AND THE EFFICIENCY AND TOXICITY OF CANCER THERAPY |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20070924 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR |
|
| DAX | Request for extension of the european patent (deleted) | ||
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20100317 |
|
| 17Q | First examination report despatched |
Effective date: 20110401 |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: JANSSEN DIAGNOSTICS, LLC |
|
| GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
| INTG | Intention to grant announced |
Effective date: 20150410 |
|
| GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
| GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
| AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR |
|
| REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
| REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 748169 Country of ref document: AT Kind code of ref document: T Effective date: 20150915 Ref country code: CH Ref legal event code: EP |
|
| REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: WEINMANN ZIMMERLI, CH |
|
| REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602005047456 Country of ref document: DE |
|
| REG | Reference to a national code |
Ref country code: NL Ref legal event code: FP |
|
| REG | Reference to a national code |
Ref country code: DK Ref legal event code: T3 Effective date: 20151201 |
|
| REG | Reference to a national code |
Ref country code: SE Ref legal event code: TRGR |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151210 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 |
|
| REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 12 |
|
| REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
| REG | Reference to a national code |
Ref country code: AT Ref legal event code: UEP Ref document number: 748169 Country of ref document: AT Kind code of ref document: T Effective date: 20150909 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160109 Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160111 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602005047456 Country of ref document: DE |
|
| PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
| 26N | No opposition filed |
Effective date: 20160610 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 |
|
| REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 13 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20050314 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150909 |
|
| REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 14 |
|
| P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230530 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: LU Payment date: 20240227 Year of fee payment: 20 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IE Payment date: 20240223 Year of fee payment: 20 Ref country code: NL Payment date: 20240226 Year of fee payment: 20 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: AT Payment date: 20240226 Year of fee payment: 20 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20240220 Year of fee payment: 20 Ref country code: GB Payment date: 20240222 Year of fee payment: 20 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: TR Payment date: 20240219 Year of fee payment: 20 Ref country code: SE Payment date: 20240226 Year of fee payment: 20 Ref country code: PL Payment date: 20240216 Year of fee payment: 20 Ref country code: IT Payment date: 20240227 Year of fee payment: 20 Ref country code: FR Payment date: 20240223 Year of fee payment: 20 Ref country code: DK Payment date: 20240314 Year of fee payment: 20 Ref country code: BE Payment date: 20240229 Year of fee payment: 20 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CH Payment date: 20240401 Year of fee payment: 20 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 602005047456 Country of ref document: DE Ref country code: CH Ref legal event code: PL |
|
| REG | Reference to a national code |
Ref country code: DK Ref legal event code: EUP Expiry date: 20250314 |
|
| REG | Reference to a national code |
Ref country code: NL Ref legal event code: MK Effective date: 20250313 |
|
| REG | Reference to a national code |
Ref country code: GB Ref legal event code: PE20 Expiry date: 20250313 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20250314 |
|
| REG | Reference to a national code |
Ref country code: IE Ref legal event code: MK9A |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20250313 |
|
| REG | Reference to a national code |
Ref country code: SE Ref legal event code: EUG |
|
| REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK07 Ref document number: 748169 Country of ref document: AT Kind code of ref document: T Effective date: 20250314 |
|
| REG | Reference to a national code |
Ref country code: BE Ref legal event code: MK Effective date: 20250314 |