EP2123272A4 - Adam inhibitor - Google Patents

Adam inhibitor

Info

Publication number
EP2123272A4
EP2123272A4 EP07860343A EP07860343A EP2123272A4 EP 2123272 A4 EP2123272 A4 EP 2123272A4 EP 07860343 A EP07860343 A EP 07860343A EP 07860343 A EP07860343 A EP 07860343A EP 2123272 A4 EP2123272 A4 EP 2123272A4
Authority
EP
European Patent Office
Prior art keywords
adam inhibitor
adam
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07860343A
Other languages
German (de)
French (fr)
Other versions
EP2123272A1 (en
Inventor
Takuya Hiruma
Hirotada Fukunishi
Masaru Suetsugu
Yukiko Matsunaga
Satoshi Amano
Michio Shibata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shiseido Co Ltd
Original Assignee
Shiseido Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Co Ltd filed Critical Shiseido Co Ltd
Publication of EP2123272A1 publication Critical patent/EP2123272A1/en
Publication of EP2123272A4 publication Critical patent/EP2123272A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP07860343A 2007-01-26 2007-12-27 Adam inhibitor Withdrawn EP2123272A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007016536A JP2008184387A (en) 2007-01-26 2007-01-26 Adam inhibitor
PCT/JP2007/075121 WO2008090717A1 (en) 2007-01-26 2007-12-27 Adam inhibitor

Publications (2)

Publication Number Publication Date
EP2123272A1 EP2123272A1 (en) 2009-11-25
EP2123272A4 true EP2123272A4 (en) 2010-04-21

Family

ID=39644292

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07860343A Withdrawn EP2123272A4 (en) 2007-01-26 2007-12-27 Adam inhibitor

Country Status (7)

Country Link
US (1) US20100113590A1 (en)
EP (1) EP2123272A4 (en)
JP (1) JP2008184387A (en)
KR (1) KR20090112629A (en)
CN (1) CN101594860A (en)
TW (1) TW200835506A (en)
WO (1) WO2008090717A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2955493B1 (en) * 2010-01-28 2012-02-24 Oreal USE OF ASCORBIC ACID DERIVATIVES IN COLORATION OF HUMAN KERATINOUS FIBERS, COMPOSITION COMPRISING SAME, COLORING METHOD AND DEVICE
JP5888667B2 (en) * 2010-04-30 2016-03-22 国立大学法人名古屋大学 ADAM action inhibitor screening method, temporary foot retention method, temporary foot retention agent, provisional foot control substance screening method, and ADAM activity inhibitor
EP2660600B1 (en) * 2010-12-28 2018-08-08 Sumitomo Dainippon Pharma Co., Ltd. Diagnostic drug and diagnostic method for alzheimer's disease
DE102013208865A1 (en) * 2013-05-14 2014-11-20 Beiersdorf Ag Stabilized preparations containing ascorbic acid and phosphate ions
CN106659662A (en) * 2014-06-10 2017-05-10 味之素株式会社 Cosmetic composition containing 3-o-alkyl-l-ascorbic acid or salt thereof
CN113543764B (en) * 2019-03-04 2024-06-11 丸善制药株式会社 Topicals

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH045214A (en) * 1990-04-21 1992-01-09 Atsushi Nonaka Cosmetic and drug for external use containing ascorbic acid derivative
JPH04128225A (en) * 1989-09-12 1992-04-28 Kokuritsu Gan Center Souchiyou Antitumor agent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62221611A (en) * 1986-03-20 1987-09-29 Kanebo Ltd Skin cosmetic
JPH07112966B2 (en) * 1986-03-26 1995-12-06 鐘紡株式会社 Skin cosmetics
JPH0667834B2 (en) * 1989-03-09 1994-08-31 二郎 藤本 Antitumor agent
JPH0558892A (en) * 1991-09-06 1993-03-09 Jiro Fujimoto Carcinogenesesis-preventing agent
TW325997B (en) * 1993-02-02 1998-02-01 Senju Pharma Co Pharmaceutical composition for preventing and treating retinal diseases
WO1996030012A1 (en) * 1995-03-24 1996-10-03 Defeudis Francis V Methods for treating conditions associated with excess nitric oxide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04128225A (en) * 1989-09-12 1992-04-28 Kokuritsu Gan Center Souchiyou Antitumor agent
JPH045214A (en) * 1990-04-21 1992-01-09 Atsushi Nonaka Cosmetic and drug for external use containing ascorbic acid derivative

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 199208, Derwent World Patents Index; AN 1992-060676, XP002571745 *
DATABASE WPI Week 199223, Derwent World Patents Index; AN 1992-190099, XP002571746 *
LAVRENOV S N ET AL: "L-Ascorbic Acid: Properties and Ways of Modification (A Review)", PHARMACEUTICAL CHEMISTRY JOURNAL, KLUWER ACADEMIC PUBLISHERS-CONSULTANTS BUREAU, NE, vol. 39, no. 5, 1 May 2005 (2005-05-01), pages 251 - 264, XP019290484, ISSN: 1573-9031 *
See also references of WO2008090717A1 *
YANG P ET AL: "The ADAMs family: Coordinators of nervous system development, plasticity and repair", PROGRESS IN NEUROBIOLOGY, PERGAMON PRESS, GB, vol. 79, no. 2, 1 June 2006 (2006-06-01), pages 73 - 94, XP025050607, ISSN: 0301-0082, [retrieved on 20060601] *

Also Published As

Publication number Publication date
TW200835506A (en) 2008-09-01
EP2123272A1 (en) 2009-11-25
JP2008184387A (en) 2008-08-14
WO2008090717A1 (en) 2008-07-31
CN101594860A (en) 2009-12-02
KR20090112629A (en) 2009-10-28
US20100113590A1 (en) 2010-05-06

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