EP2126580A4 - REAGENTS FOR DETECTING PHOSPHORYLATION OF PROTEINS IN LEUKEMIA SIGNALING PATHWAYS - Google Patents

REAGENTS FOR DETECTING PHOSPHORYLATION OF PROTEINS IN LEUKEMIA SIGNALING PATHWAYS

Info

Publication number
EP2126580A4
EP2126580A4 EP06718094A EP06718094A EP2126580A4 EP 2126580 A4 EP2126580 A4 EP 2126580A4 EP 06718094 A EP06718094 A EP 06718094A EP 06718094 A EP06718094 A EP 06718094A EP 2126580 A4 EP2126580 A4 EP 2126580A4
Authority
EP
European Patent Office
Prior art keywords
reagents
proteins
signaling pathways
detecting phosphorylation
leukemia signaling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06718094A
Other languages
German (de)
French (fr)
Other versions
EP2126580A2 (en
Inventor
Valerie Goss
Albrecht Moritz
Ting-Lei Gu
Kimberly Lee
Roberto Polakiewicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Signaling Technology Inc
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Signaling Technology Inc filed Critical Cell Signaling Technology Inc
Publication of EP2126580A2 publication Critical patent/EP2126580A2/en
Publication of EP2126580A4 publication Critical patent/EP2126580A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP06718094A 2005-02-10 2006-01-12 REAGENTS FOR DETECTING PHOSPHORYLATION OF PROTEINS IN LEUKEMIA SIGNALING PATHWAYS Withdrawn EP2126580A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65158305P 2005-02-10 2005-02-10
PCT/US2006/000979 WO2006086111A2 (en) 2005-02-10 2006-01-12 Reagents for the detection of protein phosphorylation in leukemia signaling pathways

Publications (2)

Publication Number Publication Date
EP2126580A2 EP2126580A2 (en) 2009-12-02
EP2126580A4 true EP2126580A4 (en) 2010-11-10

Family

ID=36793552

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06718094A Withdrawn EP2126580A4 (en) 2005-02-10 2006-01-12 REAGENTS FOR DETECTING PHOSPHORYLATION OF PROTEINS IN LEUKEMIA SIGNALING PATHWAYS

Country Status (2)

Country Link
EP (1) EP2126580A4 (en)
WO (1) WO2006086111A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101321782A (en) 2005-12-01 2008-12-10 纽约血库公司 Peptide inhibitors of ABL kinase
WO2008153636A1 (en) * 2007-05-04 2008-12-18 Cellsignaling Technology, Inc. Phospho-specific antibodies to p13k regulatory subunit and uses thereof
CN101802182A (en) 2007-08-21 2010-08-11 诺达利蒂公司 Methods for diagnosis, prognosis, and methods of treatment
US8399206B2 (en) 2008-07-10 2013-03-19 Nodality, Inc. Methods for diagnosis, prognosis and methods of treatment
US8227202B2 (en) 2008-07-10 2012-07-24 Nodality, Inc. Methods for diagnosis, prognosis and methods of treatment
JP6153467B2 (en) 2010-05-31 2017-06-28 ロンドン ヘルス サイエンシーズ センター リサーチ インコーポレイテッドＬｏｎｄｏｎ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ Ｃｅｎｔｒｅ Ｒｅｓｅａｒｃｈ Ｉｎｃ． RHAMM binding peptide
DE102010033575B4 (en) * 2010-08-02 2016-01-14 Eberhard-Karls-Universität Tübingen Universitätsklinikum ASPP2 splice variant
GB201322574D0 (en) * 2013-12-19 2014-02-05 Equigerminal Sa Retroviral peptides
WO2020097096A1 (en) * 2018-11-05 2020-05-14 The Brigham And Women's Hospital, Inc. Nedd9 in pulmonary vascular thromboembolic disease
SG11202104352XA (en) 2018-12-18 2021-05-28 Boehringer Ingelheim Io Canada Inc Flt3 agonist antibodies and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003070899A2 (en) * 2002-02-20 2003-08-28 Cell Signaling Technology, Inc. Phospho-specific antibodies to flt3 and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599305A (en) * 1984-07-16 1986-07-08 The Regents Of The University Of California Method and composition for detection of human chronic myelogenous leukemia
US5667981A (en) * 1994-05-13 1997-09-16 Childrens Hospital Of Los Angeles Diagnostics and treatments for cancers expressing tyrosine phosphorylated CRKL protein

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003070899A2 (en) * 2002-02-20 2003-08-28 Cell Signaling Technology, Inc. Phospho-specific antibodies to flt3 and uses thereof

Also Published As

Publication number Publication date
WO2006086111A3 (en) 2009-04-16
EP2126580A2 (en) 2009-12-02
WO2006086111A2 (en) 2006-08-17

Similar Documents

Publication Publication Date Title
DE602006017622D1 (en) Fluorescence detection system
EP2340555A4 (en) PROBE BLOCK ASSEMBLY
EP2041559A4 (en) Rapid analyte measurement assay
EP1869828A4 (en) NETWORK ELEMENT ARCHITECTURE FOR PACKET INSPECTION IN DEPTH
EP2004896A4 (en) AUTOMATIC CALIBRATION OF POINTS IN AN EXTRUDER
EP1920181A4 (en) FITTED ASSEMBLY FOR PIPING CONNECTIONS
EP2406621A4 (en) ELECTRICAL SENSOR FOR ULTRASENSITIVE DETECTION OF NUCLEIC ACID
EP2068939A4 (en) METHODS FOR SCREENING AGENTS FOR DETECTING ACTIVITY IN TELEOSTS
BRPI0820718A2 (en) Quick read port amperometry
EP2171080A4 (en) METHODS OF PROTEIN DETECTION IN PLASMA
EP2356459A4 (en) METHODS OF DETECTING NEUROLOGICAL PATHOLOGY THROUGH PHAGOCYTE ANALYSIS IN CIRCULATION
EP2019836A4 (en) METHODS, COMPOSITIONS AND KITS FOR DETECTING PROTEIN AGGREGATES
DE602007006195D1 (en) Mechanism for detecting data bus detection
EP2126580A4 (en) REAGENTS FOR DETECTING PHOSPHORYLATION OF PROTEINS IN LEUKEMIA SIGNALING PATHWAYS
FR2881436B1 (en) METHOD FOR DETERMINING THE DIVERSITY OF T LYMPHOCYTES IN A BIOLOGICAL SAMPLE
EP2103929A4 (en) SUBSTANCE DETECTION SENSOR
FI20085461L (en) Sensor for detecting conductive objects
DK1931695T3 (en) Prion-Specific Peptoid Reagents
EP2177905A4 (en) MICROALGA BASED BIOSENSORS FOR DETECTION OF ENVIRONMENTAL CONTAMINANTS
EP1933156A4 (en) DEVICE FOR DETECTING ZERO CURRENT
DE602006006359D1 (en) Device for detecting antenna errors
DE502008002117D1 (en) Sensor arrangement for detecting objects
EP1604613A4 (en) CATHETER SENSOR FOR MEASURING HARDNESS
EP1929003A4 (en) Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
EP1981993A4 (en) METHODS FOR DETECTING PICS IN A TRACE OF NUCLEIC ACID VARIABLES

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20071123

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

A4 Supplementary search report drawn up and despatched

Effective date: 20101013

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20110503