EP2150243A4 - Compositions and methods for enhancing active agent absorption - Google Patents

Compositions and methods for enhancing active agent absorption

Info

Publication number: EP2150243A4
Authority: EP; European Patent Office
Prior art keywords: compositions; methods; active agent; agent absorption; enhancing active
Prior art date: 2007-05-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP08755962.1A

Other languages

German (de)

French (fr)

Other versions

EP2150243A2 (en

Inventor

Chung Shih

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

NexusPharma Inc

Original Assignee

NexusPharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-21

Filing date

2008-05-20

Publication date

2013-08-21

2007-05-21 Priority claimed from US11/805,202 external-priority patent/US8426466B2/en

2008-05-20 Application filed by NexusPharma Inc filed Critical NexusPharma Inc

2010-02-10 Publication of EP2150243A2 publication Critical patent/EP2150243A2/en

2013-08-21 Publication of EP2150243A4 publication Critical patent/EP2150243A4/en

Status Withdrawn legal-status Critical Current

Links

238000010521 absorption reaction Methods 0.000 title 1
239000013543 active substance Substances 0.000 title 1
230000002708 enhancing effect Effects 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP08755962.1A 2007-05-21 2008-05-20 Compositions and methods for enhancing active agent absorption Withdrawn EP2150243A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11/805,202 US8426466B2 (en)	2006-05-22	2007-05-21	Compositions and methods for enhancing active agent absorption
US409907P	2007-11-21	2007-11-21
PCT/US2008/064233 WO2008144690A2 (en)	2007-05-21	2008-05-20	Compositions and methods for enhancing active agent absorption

Publications (2)

Publication Number	Publication Date
EP2150243A2 EP2150243A2 (en)	2010-02-10
EP2150243A4 true EP2150243A4 (en)	2013-08-21

Family

ID=40122287

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP08755962.1A Withdrawn EP2150243A4 (en)	2007-05-21	2008-05-20	Compositions and methods for enhancing active agent absorption

Country Status (2)

Country	Link
EP (1)	EP2150243A4 (en)
WO (1)	WO2008144690A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN104906592B (en) *	2011-02-25	2017-11-03	广州南沙龙沙有限公司	Branched Linkers for Protein Drug Conjugates
EP3031905A4 (en) *	2013-08-07	2017-04-26	Kyoto University	Method for producing pancreatic hormone-producing cell

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5773647A (en) *	1997-02-07	1998-06-30	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5817624A (en) *	1995-06-05	1998-10-06	Alza Corporation	Permeation enhancer compositions for increased absorption of therapeutic proteins through the colonic membrane
NZ520238A (en) *	2000-01-27	2004-04-30	Peros Systemes Technologies In	Composition for intestinal delivery
US20030198666A1 (en) *	2002-01-07	2003-10-23	Richat Abbas	Oral insulin therapy
CN100522243C (en) *	2006-03-13	2009-08-05	新疆维吾尔自治区畜牧科学院兽医研究所	Animal skin penetrant

2008
- 2008-05-20 WO PCT/US2008/064233 patent/WO2008144690A2/en not_active Ceased
- 2008-05-20 EP EP08755962.1A patent/EP2150243A4/en not_active Withdrawn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5773647A (en) *	1997-02-07	1998-06-30	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FAUST JOHN A ET AL: "Derivatives of salicylamide", AMERICAN PHARMACEUTICAL ASSOCIATION. JOURNAL, AMERICAN PHARMACISTS ASSOCIATION, US, vol. 45, no. 8, 20 February 1956 (1956-02-20), pages 514 - 517, XP008115755, ISSN: 0003-0465, [retrieved on 20060923], DOI: 10.1002/JPS.3030450803 *
NAITO MASUKAZU ET AL: "Chemotherapeutics for Mycobacterium tuberculosis. XII. Antibacterial activity of derivatives of esters of p-aminosalicylic acid on Mycobacterium tuberculosis", YAKUGAKU ZASSHI, PHARMACEUTICAL SOCIETY OF JAPAN, JP, vol. 78, no. 6, 1 January 1958 (1958-01-01), pages 682 - 683, XP008115756, ISSN: 0031-6903 *
See also references of WO2008144690A2 *
XUAN DING ET AL: "Oral Absorption Enhancement of Cromolyn Sodium Through Noncovalent Complexation", PHARMACEUTICAL RESEARCH, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NL, vol. 21, no. 12, 1 December 2004 (2004-12-01), pages 2196 - 2206, XP019370659, ISSN: 1573-904X, DOI: 10.1007/S11095-004-7671-9 *

Also Published As

Publication number	Publication date
WO2008144690A2 (en)	2008-11-27
EP2150243A2 (en)	2010-02-10
WO2008144690A3 (en)	2009-02-26

Legal Events

Date	Code	Title	Description
2010-01-08	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2010-02-10	17P	Request for examination filed	Effective date: 20091123
2010-02-10	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR
2010-02-10	AX	Request for extension of the european patent	Extension state: AL BA MK RS
2012-08-15	DAX	Request for extension of the european patent (deleted)
2013-08-21	A4	Supplementary search report drawn up and despatched	Effective date: 20130724
2013-08-21	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 47/10 20060101ALI20130718BHEP Ipc: A61K 9/00 20060101ALI20130718BHEP Ipc: A61K 38/16 20060101AFI20130718BHEP Ipc: A61K 47/18 20060101ALI20130718BHEP Ipc: A61K 31/715 20060101ALI20130718BHEP
2016-04-22	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2016-05-25	18D	Application deemed to be withdrawn	Effective date: 20151201

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