EP2366409A4 - THERMOSENSITIVE COMPOSITION PREVENTING TISSUE ADHESION AND METHOD OF PREPARING THE SAME - Google Patents

THERMOSENSITIVE COMPOSITION PREVENTING TISSUE ADHESION AND METHOD OF PREPARING THE SAME

Info

Publication number
EP2366409A4
EP2366409A4 EP09827667.8A EP09827667A EP2366409A4 EP 2366409 A4 EP2366409 A4 EP 2366409A4 EP 09827667 A EP09827667 A EP 09827667A EP 2366409 A4 EP2366409 A4 EP 2366409A4
Authority
EP
European Patent Office
Prior art keywords
preparing
same
tissue adhesion
preventing tissue
composition preventing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP09827667.8A
Other languages
German (de)
French (fr)
Other versions
EP2366409B1 (en
EP2366409A2 (en
Inventor
Jin-Suk Choi
Young-Woo Lee
Yun-Gee Lee
Jun-Ho Kim
Jin-Ho Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GENEWEL CO Ltd
Institute for Industry Academia Cooperation of Hannam University
Original Assignee
GENEWEL CO Ltd
Institute for Industry Academia Cooperation of Hannam University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GENEWEL CO Ltd, Institute for Industry Academia Cooperation of Hannam University filed Critical GENEWEL CO Ltd
Priority to PL09827667T priority Critical patent/PL2366409T3/en
Publication of EP2366409A2 publication Critical patent/EP2366409A2/en
Publication of EP2366409A4 publication Critical patent/EP2366409A4/en
Application granted granted Critical
Publication of EP2366409B1 publication Critical patent/EP2366409B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polymers & Plastics (AREA)
EP09827667.8A 2008-11-19 2009-09-17 Thermosensitive composition preventing tissue adhesion and preparation method thereof Active EP2366409B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL09827667T PL2366409T3 (en) 2008-11-19 2009-09-17 Thermosensitive composition preventing tissue adhesion and preparation method thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020080114946A KR101125934B1 (en) 2008-11-19 2008-11-19 Temperature Sensitive Tissue Adhesion Prevention Composition And Method For Preparing Thereof
PCT/KR2009/005280 WO2010058902A2 (en) 2008-11-19 2009-09-17 Thermosensitive composition preventing tissue adhesion and preparation method thereof

Publications (3)

Publication Number Publication Date
EP2366409A2 EP2366409A2 (en) 2011-09-21
EP2366409A4 true EP2366409A4 (en) 2013-07-31
EP2366409B1 EP2366409B1 (en) 2014-12-10

Family

ID=42198618

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09827667.8A Active EP2366409B1 (en) 2008-11-19 2009-09-17 Thermosensitive composition preventing tissue adhesion and preparation method thereof

Country Status (10)

Country Link
US (1) US9095643B2 (en)
EP (1) EP2366409B1 (en)
JP (1) JP5604440B2 (en)
KR (1) KR101125934B1 (en)
CN (1) CN102245212B (en)
DK (1) DK2366409T3 (en)
ES (1) ES2526453T3 (en)
PL (1) PL2366409T3 (en)
PT (1) PT2366409E (en)
WO (1) WO2010058902A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013015579A2 (en) * 2011-07-26 2013-01-31 (주)차바이오앤디오스텍 Medical composite organic material including collagen and hyaluronic acid derivatives
KR101330652B1 (en) 2012-02-28 2013-11-18 (주)시지바이오 Anti―adhesion polymer composition able to load growth factors
KR101389831B1 (en) * 2012-05-25 2014-05-07 한남대학교 산학협력단 Thermo-responsive adhesion barrier agent
US20150209481A1 (en) * 2012-08-16 2015-07-30 Nipro Corporation Antiadhesive Material
CN104027850A (en) * 2014-06-03 2014-09-10 陈凯 Postoperative washing agent and preparation method thereof
KR101627787B1 (en) * 2014-07-24 2016-06-07 주식회사 메디톡스 Thermosensitive composition for preventing adhension and use thereof
PL409231A1 (en) * 2014-08-21 2016-02-29 Warszawski Uniwersytet Medyczny Method for producing intramedullary nails from chitosan for treatment of long bone fractures
KR101852718B1 (en) 2017-04-04 2018-05-18 주식회사 제네웰 Kit for pain reduction of incision site after surgical operation
KR101923734B1 (en) 2017-04-13 2018-11-29 영남대학교 산학협력단 A crosslinked film for adhesion prevention
KR101981562B1 (en) * 2017-05-04 2019-05-24 주식회사 테라시온 바이오메디칼 Method for manufacturing anti-adhesion composition
CN108159508B (en) * 2018-01-03 2021-01-26 东南大学 A kind of preparation method of anti-adhesion medical hydrogel material
KR101902956B1 (en) 2018-03-13 2018-10-02 주식회사 제네웰 Kit for pain reduction of incision site after surgical operation
KR102065016B1 (en) 2018-04-17 2020-01-10 주식회사 제네웰 Kit for pain reduction or healing of incision site after surgical operation
KR102144479B1 (en) * 2018-05-24 2020-08-13 주식회사 덱스레보 Composition for tissue repair treatment and methods of manufacturing the same
KR102251192B1 (en) * 2020-08-07 2021-05-13 주식회사 덱스레보 Composition for tissue repair treatment and methods of manufacturing the same
CN117618533B (en) * 2023-11-28 2024-08-06 上海市第四人民医院 Photosensitive curing spray and preparation method and application thereof
CN120899734B (en) * 2025-08-08 2026-04-21 湖南科迈森医疗科技有限公司 Chitosan-hyaluronic acid hydrogel composition based on astragaloside IV and salvianolic acid B, and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004971A1 (en) * 1988-11-03 1990-05-17 M.D.R. Group, Inc. Improved viscoelastic fluid for use in surgery and other therapies and method of using same
JPH08231435A (en) * 1995-02-27 1996-09-10 Res Dev Corp Of Japan Biodegradable polymer hydrogel
US20050096445A1 (en) * 2002-05-07 2005-05-05 Eberhard Fuchs Method for producing an aqueous alkali acrylate solution

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4188373A (en) 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4271281A (en) * 1980-05-29 1981-06-02 American Hoechst Corporation Process for preparing styrenic polymer particles
US4478822A (en) 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4474751A (en) 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US5939485A (en) 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
US6696499B1 (en) * 1996-07-11 2004-02-24 Life Medical Sciences, Inc. Methods and compositions for reducing or eliminating post-surgical adhesion formation
JPH10235230A (en) * 1997-02-28 1998-09-08 Igarashi Kogyo Kk Oil treating agent scattering device
JP2000281794A (en) * 1999-03-30 2000-10-10 Dainippon Ink & Chem Inc Preparation of water-absorbing resin
AU778853B2 (en) * 1999-04-02 2004-12-23 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
KR20030050953A (en) 2001-12-20 2003-06-25 주식회사 하이닉스반도체 Method for forming multi-level metal wiring of semiconductor device
KR100565881B1 (en) * 2003-07-24 2006-03-29 이진호 Anti-tissue adhesion agent using biocompatible copolymer
JP2005139293A (en) * 2003-11-06 2005-06-02 Mitsui Chemicals Inc Sulfur dispersion for rubber crosslinking
JP5026665B2 (en) 2004-10-15 2012-09-12 株式会社フジミインコーポレーテッド Polishing composition and polishing method using the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004971A1 (en) * 1988-11-03 1990-05-17 M.D.R. Group, Inc. Improved viscoelastic fluid for use in surgery and other therapies and method of using same
JPH08231435A (en) * 1995-02-27 1996-09-10 Res Dev Corp Of Japan Biodegradable polymer hydrogel
US20050096445A1 (en) * 2002-05-07 2005-05-05 Eberhard Fuchs Method for producing an aqueous alkali acrylate solution

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"Aqualon Sodium Carboxymethylcellulose - Physical and Chemical Properties", 12 December 1999 (1999-12-12), XP055066985, Retrieved from the Internet <URL:http://www.ashland.com/Ashland/Static/Documents/AAFI/PRO-250-10H_Aqualon_CMC.pdf> [retrieved on 20130617] *
"Pluronic F-127", 9 January 2008 (2008-01-09), XP055066983, Retrieved from the Internet <URL:http://probes.invitrogen.com/media/pis/mp03000.pdf> [retrieved on 20130617] *
See also references of WO2010058902A2 *

Also Published As

Publication number Publication date
WO2010058902A3 (en) 2010-07-15
US9095643B2 (en) 2015-08-04
EP2366409B1 (en) 2014-12-10
WO2010058902A2 (en) 2010-05-27
CN102245212B (en) 2014-06-18
JP2012509129A (en) 2012-04-19
PT2366409E (en) 2015-01-13
DK2366409T3 (en) 2015-01-12
KR101125934B1 (en) 2012-03-21
KR20100056009A (en) 2010-05-27
CN102245212A (en) 2011-11-16
ES2526453T3 (en) 2015-01-12
JP5604440B2 (en) 2014-10-08
EP2366409A2 (en) 2011-09-21
PL2366409T3 (en) 2015-03-31
US20110229432A1 (en) 2011-09-22

Similar Documents

Publication Publication Date Title
EP2366409A4 (en) THERMOSENSITIVE COMPOSITION PREVENTING TISSUE ADHESION AND METHOD OF PREPARING THE SAME
EP2343339A4 (en) ADHESIVE COMPOSITION AND METHOD OF BONDING
EP2252686A4 (en) COMPOSITIONS AND METHODS FOR IMPLANTATION OF ADIPOSE TISSUE AND ADIPOSE TISSUE PRODUCTS
EP2321302A4 (en) PROCESS FOR THE PREPARATION OF AZACITIDINE AND POLYMORPHIC
IL184403A0 (en) Method and composition for treating mammalian diseases and injuries caused by the over expression of peroxynitrite
EP1986554A4 (en) TISSUE STOPPING POINT
EP2352559A4 (en) SYSTEMS AND METHODS FOR ABLATION OF BODY TISSUE
IL211592A0 (en) Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
BRPI0819567A2 (en) &#34;Antimicrobial Compositions, Method for Improving Wet Adhesion of Medical Adhesive Article and Method for Avoiding or Treating a Mammalian Skin Condition&#34;
EP2018129A4 (en) DEVICE FOR ABLATION OF BODY TISSUE
PL3398606T3 (en) Microalgae-derived compositions for improving the health and appearance of skin
DE102009035301A8 (en) Process for the preparation of dibenz [c, e] [1,2] oxaphosphorine derivatives, amino dibenz [c, e] [1,2] oxaphosphorine and their use
SI2432792T1 (en) And process for the preparation of n-((2&#39;r)-2&#39;-deoxy-2&#39;-fluoro-2&#39;-methyl-p-phenyl-5&#39;-uridylyl)-l-alanine 1-methylethyl ester
EP2250999A4 (en) WHITENING AGENT FOR THE SKIN AND EXTERNAL SKIN PREPARATION
BRPI0916550A2 (en) compositions comprising sweetness enhancers and methods of producing same
EP2396342A4 (en) EXPRESSION OF MUTANT ROS PROTEIN IN CANCERS IN HUMAN BEINGS
WO2007125105A3 (en) Benzamide glucokinase activators
EP2349305A4 (en) PHYTOCHEMICAL COMPOSITIONS AND METHODS FOR ACTIVATION OF AMP KINASE
ATE512970T1 (en) DIMERS OF ARTEMISIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE
BRPI1015441A2 (en) &#34;composition comprising caffeoyloxycemic acids, protocatechuic acid hydroxytyrosol, hydroxybenzoic acid and derivatives thereof, and method of preparation&#34;
IL205350A0 (en) Novel 1, 3- dihydro - 5 - isobenzofurancarbonitrile derivatives and pharmacetical composition thereof for the treatment of premature ejaculation
GB0909297D0 (en) Composition for the treatment of skin conditions
ZA201007091B (en) Vaccine compositions for the treatment of dengue fever and uses thereof
FR2940073B1 (en) MAKE-UP COMPOSITION OF KERATINIC MATERIAL COMPRISING AT LEAST ONE NON-CATIONIC OXIDE POLYSACCHARIDE
EP2377865A4 (en) CYCLOBUTYL PURINE DERIVATIVE, ANGIOGENESIS PROMOTING AGENT, LUMENIZATION PROMOTING AGENT, NEUROCYTE GROWTH PROMOTING AGENT AND MEDICAMENT

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20110525

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20130702

RIC1 Information provided on ipc code assigned before grant

Ipc: A61L 27/26 20060101ALI20130624BHEP

Ipc: A61L 27/18 20060101ALI20130624BHEP

Ipc: A61K 47/30 20060101AFI20130624BHEP

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Ref document number: 602009028308

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: A61K0047300000

Ipc: A61L0031040000

RIC1 Information provided on ipc code assigned before grant

Ipc: A61L 31/14 20060101ALI20140516BHEP

Ipc: A61L 31/04 20060101AFI20140516BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20140701

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2526453

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20150112

Ref country code: DK

Ref legal event code: T3

Effective date: 20150109

REG Reference to a national code

Ref country code: PT

Ref legal event code: SC4A

Free format text: AVAILABILITY OF NATIONAL TRANSLATION

Effective date: 20150107

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 700330

Country of ref document: AT

Kind code of ref document: T

Effective date: 20150115

REG Reference to a national code

Ref country code: SE

Ref legal event code: TRGR

REG Reference to a national code

Ref country code: NL

Ref legal event code: T3

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602009028308

Country of ref document: DE

Effective date: 20150122

REG Reference to a national code

Ref country code: NO

Ref legal event code: T2

Effective date: 20141210

REG Reference to a national code

Ref country code: PL

Ref legal event code: T3

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 700330

Country of ref document: AT

Kind code of ref document: T

Effective date: 20141210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

REG Reference to a national code

Ref country code: HU

Ref legal event code: AG4A

Ref document number: E022612

Country of ref document: HU

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150311

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150410

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602009028308

Country of ref document: DE

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20150911

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150917

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150917

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 8

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 9

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141210

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 10

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FI

Payment date: 20190919

Year of fee payment: 11

Ref country code: PT

Payment date: 20190909

Year of fee payment: 11

Ref country code: NL

Payment date: 20190918

Year of fee payment: 11

Ref country code: DK

Payment date: 20190923

Year of fee payment: 11

Ref country code: NO

Payment date: 20190919

Year of fee payment: 11

Ref country code: TR

Payment date: 20190910

Year of fee payment: 11

Ref country code: SE

Payment date: 20190923

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: PL

Payment date: 20190916

Year of fee payment: 11

Ref country code: HU

Payment date: 20190924

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20190917

Year of fee payment: 11

REG Reference to a national code

Ref country code: DE

Ref legal event code: R082

Ref document number: 602009028308

Country of ref document: DE

REG Reference to a national code

Ref country code: FI

Ref legal event code: MAE

REG Reference to a national code

Ref country code: NO

Ref legal event code: MMEP

Ref country code: DK

Ref legal event code: EBP

Effective date: 20200930

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200917

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: NL

Ref legal event code: MM

Effective date: 20201001

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20201001

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NO

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200930

Ref country code: PT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20210413

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200918

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200930

Ref country code: HU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200918

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200930

REG Reference to a national code

Ref country code: SE

Ref legal event code: EUG

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200930

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200917

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200917

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20250917

Year of fee payment: 17

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20250918

Year of fee payment: 17

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20250829

Year of fee payment: 17

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20250917

Year of fee payment: 17

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20251007

Year of fee payment: 17