EP2763540A4 - COMPOSITIONS AND METHODS FOR EVALUATION AND TREATMENT OF DISEASES AND INFLAMMATORY DISORDERS - Google Patents
COMPOSITIONS AND METHODS FOR EVALUATION AND TREATMENT OF DISEASES AND INFLAMMATORY DISORDERSInfo
- Publication number
- EP2763540A4 EP2763540A4 EP12829361.0A EP12829361A EP2763540A4 EP 2763540 A4 EP2763540 A4 EP 2763540A4 EP 12829361 A EP12829361 A EP 12829361A EP 2763540 A4 EP2763540 A4 EP 2763540A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- diseases
- evaluation
- compositions
- treatment
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 238000011156 evaluation Methods 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161532902P | 2011-09-09 | 2011-09-09 | |
| US201261584988P | 2012-01-10 | 2012-01-10 | |
| PCT/US2012/033753 WO2013036290A1 (en) | 2011-09-09 | 2012-04-16 | Compositions and methods for assessing and treating inflammatory diseases and disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2763540A1 EP2763540A1 (en) | 2014-08-13 |
| EP2763540A4 true EP2763540A4 (en) | 2015-04-22 |
Family
ID=47832488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP12829361.0A Withdrawn EP2763540A4 (en) | 2011-09-09 | 2012-04-16 | COMPOSITIONS AND METHODS FOR EVALUATION AND TREATMENT OF DISEASES AND INFLAMMATORY DISORDERS |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP2763540A4 (en) |
| WO (1) | WO2013036290A1 (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2217250A4 (en) | 2007-11-09 | 2011-01-05 | California Inst Of Techn | IMMUNOREGULATORY COMPOUNDS AND RELATED COMPOSITIONS AND METHODS |
| HUE040658T2 (en) | 2010-04-07 | 2019-03-28 | California Inst Of Techn | Vehicle for delivering a compound to a mucous membrane and related compositions, methods and systems |
| EP2731617A4 (en) | 2011-07-12 | 2015-07-01 | Brigham & Womens Hospital | LIPID-CONTAINING PSA COMPOSITIONS, METHODS OF ISOLATION AND METHODS OF USING SAME |
| ES2821383T3 (en) | 2012-10-17 | 2021-04-26 | Enterome | Genetic signatures of inflammatory disorders related to the liver and Crohn's disease |
| EP2969012A4 (en) | 2013-03-12 | 2016-09-14 | Univ Yale | COMPOSITIONS AND METHODS FOR IDENTIFYING MICROBES RELATED TO SECRETORY ANTIBODIES |
| WO2014182966A1 (en) * | 2013-05-10 | 2014-11-13 | California Institute Of Technology | Probiotic prevention and treatment of colon cancer |
| US10920283B2 (en) | 2013-11-01 | 2021-02-16 | Washington University | Methods to establish and restore normal gut microbiota function of subject in need thereof |
| FI127671B (en) | 2014-05-28 | 2018-11-30 | Filip Scheperjans | A method for the diagnosis of Parkinson's disease |
| WO2016033439A2 (en) | 2014-08-28 | 2016-03-03 | Yale University | Compositions and methods for the treating an inflammatory disease or disorder |
| US9968616B2 (en) | 2014-10-25 | 2018-05-15 | The Chinese University Of Hong Kong | Discovery of FDA-approved drugs as inhibitors of fatty acid binding protein 4 using molecular docking screening |
| WO2016126831A1 (en) | 2015-02-03 | 2016-08-11 | Mayo Foundation For Medical Education And Research | Methods and materials for assessing and treating arthritis |
| US11331335B2 (en) | 2015-06-10 | 2022-05-17 | California Institute Of Technology | Sepsis treatment and related compositions methods and systems |
| JP6918365B2 (en) | 2015-08-19 | 2021-08-11 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Lipidized PSA Compositions and Methods |
| US11491181B2 (en) | 2016-07-15 | 2022-11-08 | President And Fellows Of Harvard College | Glycolipid compositions and methods of use |
| JP2023531935A (en) * | 2020-06-22 | 2023-07-26 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Treatment of obesity with G protein-coupled receptor 75 (GPR75) inhibitors |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004045525A2 (en) * | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation. |
| WO2005016226A2 (en) * | 2003-08-14 | 2005-02-24 | Hadasit Medical Research Services & Development Ltd. | Pharmaceutical compositions comprising ccr5 antagonists |
| WO2011043654A1 (en) * | 2009-10-05 | 2011-04-14 | Aak Patent B.V. | Methods for diagnosing irritable bowel syndrome |
| WO2011082218A1 (en) * | 2009-12-31 | 2011-07-07 | Ira Milton Trachtman | Compositions and method for treatment and prophylaxis of inflammatory bowel disease |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4160452A (en) | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US5023243A (en) | 1981-10-23 | 1991-06-11 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and method of making same |
| US5190931A (en) | 1983-10-20 | 1993-03-02 | The Research Foundation Of State University Of New York | Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5168053A (en) | 1989-03-24 | 1992-12-01 | Yale University | Cleavage of targeted RNA by RNAase P |
| US5459039A (en) | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
| US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5288644A (en) | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
| ES2155822T3 (en) | 1990-12-06 | 2001-06-01 | Affymetrix Inc | COMPOUNDS AND ITS USE IN A BINARY SYNTHESIS STRATEGY. |
| US5384261A (en) | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
| DE69433180T2 (en) | 1993-10-26 | 2004-06-24 | Affymetrix, Inc., Santa Clara | FIELDS OF NUCLEIC ACID PROBE ON ORGANIC CHIPS |
| US6159693A (en) | 1998-03-13 | 2000-12-12 | Promega Corporation | Nucleic acid detection |
| US6270974B1 (en) | 1998-03-13 | 2001-08-07 | Promega Corporation | Exogenous nucleic acid detection |
| US20090197249A1 (en) * | 2004-11-01 | 2009-08-06 | George Mason University | Compositions and methods for diagnosing colon disorders |
| JP2012517822A (en) * | 2009-02-19 | 2012-08-09 | ガラパゴス・ナムローゼ・フェンノートシャップ | Identification method and compound useful for diagnosis and treatment of diseases including inflammation |
| WO2011025962A1 (en) * | 2009-08-28 | 2011-03-03 | Dan Allison | Antikine antibodies that bind to multiple cc chemokines |
-
2012
- 2012-04-16 WO PCT/US2012/033753 patent/WO2013036290A1/en not_active Ceased
- 2012-04-16 EP EP12829361.0A patent/EP2763540A4/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004045525A2 (en) * | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation. |
| WO2005016226A2 (en) * | 2003-08-14 | 2005-02-24 | Hadasit Medical Research Services & Development Ltd. | Pharmaceutical compositions comprising ccr5 antagonists |
| WO2011043654A1 (en) * | 2009-10-05 | 2011-04-14 | Aak Patent B.V. | Methods for diagnosing irritable bowel syndrome |
| WO2011082218A1 (en) * | 2009-12-31 | 2011-07-07 | Ira Milton Trachtman | Compositions and method for treatment and prophylaxis of inflammatory bowel disease |
Non-Patent Citations (5)
| Title |
|---|
| DELPHINE M SAULNIER ET AL: "Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome", GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, vol. 141, no. 5, 24 June 2011 (2011-06-24), pages 1782 - 1791, XP028325678, ISSN: 0016-5085, [retrieved on 20110708], DOI: 10.1053/J.GASTRO.2011.06.072 * |
| ERAN ELINAV ET AL: "NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis", CELL, CELL PRESS, US, vol. 145, no. 5, 22 April 2011 (2011-04-22), pages 745 - 757, XP028221175, ISSN: 0092-8674, [retrieved on 20110502], DOI: 10.1016/J.CELL.2011.04.022 * |
| See also references of WO2013036290A1 * |
| YANFEI CHEN ET AL: "Characterization of fecal microbial communities in patients with liver cirrhosis", HEPATOLOGY, vol. 54, no. 2, 26 June 2011 (2011-06-26), pages 562 - 572, XP055159513, ISSN: 0270-9139, DOI: 10.1002/hep.24423 * |
| YOUNES J. ERRAHALI ET AL: "CCL26-Targeted siRNA Treatment of Alveolar Type II Cells Decreases Expression of CCR3-Binding Chemokines and Reduces Eosinophil Migration: Implications in Asthma Therapy", JOURNAL OF INTERFERON & CYTOKINE RESEARCH, vol. 29, no. 4, 1 April 2009 (2009-04-01), pages 227 - 239, XP055175655, ISSN: 1079-9907, DOI: 10.1089/jir.2008.0051 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013036290A1 (en) | 2013-03-14 |
| EP2763540A1 (en) | 2014-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20140409 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
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| AX | Request for extension of the european patent |
Extension state: BA ME |
|
| RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 20150319 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A01N 63/00 20060101AFI20150313BHEP |
|
| 17Q | First examination report despatched |
Effective date: 20160420 |
|
| GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
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| INTG | Intention to grant announced |
Effective date: 20170315 |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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| 18D | Application deemed to be withdrawn |
Effective date: 20170726 |