EP2766087A4 - NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS - Google Patents

NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS

Info

Publication number: EP2766087A4
Authority: EP; European Patent Office
Prior art keywords: reasons; treatment; neurological disorders; electric stimulation; regular electric
Prior art date: 2011-10-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP12839657.9A

Other languages

German (de)

French (fr)

Other versions

EP2766087A2 (en

Inventor

Warren M Grill

David T Brocker

Merill J Birdno

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Duke University

Original Assignee

Duke University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-11

Filing date

2012-10-11

Publication date

2015-05-06

2012-10-11 Application filed by Duke University filed Critical Duke University

2012-10-11 Priority to EP20175204.5A priority Critical patent/EP3718596B1/en

2012-10-11 Priority to EP18167953.1A priority patent/EP3372274B1/en

2014-08-20 Publication of EP2766087A2 publication Critical patent/EP2766087A2/en

2015-05-06 Publication of EP2766087A4 publication Critical patent/EP2766087A4/en

Status Ceased legal-status Critical Current

Links

208000012902 Nervous system disease Diseases 0.000 title 1
208000025966 Neurological disease Diseases 0.000 title 1
230000000638 stimulation Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/36167—Timing, e.g. stimulation onset
- A61N1/36178—Burst or pulse train parameters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
- A61N1/0534—Electrodes for deep brain stimulation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36189—Control systems using modulation techniques
- A61N1/36196—Frequency modulation

Landscapes

Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Developmental Disabilities (AREA)
Psychiatry (AREA)
Child & Adolescent Psychology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Electrotherapy Devices (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP12839657.9A 2011-10-11 2012-10-11 NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS Ceased EP2766087A4 (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
EP20175204.5A EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161545791P	2011-10-11	2011-10-11
US201161558871P	2011-11-11	2011-11-11
PCT/US2012/059787 WO2013055940A2 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
EP20175204.5A Division EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Division EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Publications (2)

Publication Number	Publication Date
EP2766087A2 EP2766087A2 (en)	2014-08-20
EP2766087A4 true EP2766087A4 (en)	2015-05-06

Family

ID=48082746

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
EP12839657.9A Ceased EP2766087A4 (en)	2011-10-11	2012-10-11	NON-REGULAR ELECTRIC STIMULATION REASONS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
EP20175204.5A Active EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Active EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
EP20175204.5A Active EP3718596B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Active EP3372274B1 (en)	2011-10-11	2012-10-11	Non-regular electrical stimulation patterns for treating neurological disorders

Country Status (5)

Country	Link
EP (3)	EP2766087A4 (en)
CN (2)	CN106955417B (en)
AU (4)	AU2012322739A1 (en)
CA (2)	CA3169207A1 (en)
WO (1)	WO2013055940A2 (en)

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US11013924B2 (en)	2008-10-03	2021-05-25	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders
US8923981B2 (en)	2008-10-03	2014-12-30	Duke University	Non-regular electrical stimulation patterns designed with a cost function for treating neurological disorders
WO2010039274A1 (en)	2008-10-03	2010-04-08	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders
US8798755B2 (en)	2008-10-03	2014-08-05	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders
US9802046B2 (en)	2008-10-03	2017-10-31	Duke University	Non-regular electrical stimulation patterns for improved efficiency in treating Parkinson's Disease
CN103108670B (en)	2010-05-27	2016-10-12	Ndi医疗公司	Waveform shapes optimized for energy efficiency for treating neurological disorders
US9821159B2 (en)	2010-11-16	2017-11-21	The Board Of Trustees Of The Leland Stanford Junior University	Stimulation devices and methods
CA2817589A1 (en)	2010-11-16	2012-05-24	The Board Of Trustees Of The Leland Stanford Junior University	Systems and methods for treatment of dry eye
US12453853B2 (en)	2013-01-21	2025-10-28	Cala Health, Inc.	Multi-modal stimulation for treating tremor
EP2945691B1 (en)	2013-01-21	2019-03-06	Cala Health, Inc.	Devices for controlling tremor
US9717627B2 (en)	2013-03-12	2017-08-01	Oculeve, Inc.	Implant delivery devices, systems, and methods
EP2986339A4 (en)	2013-04-19	2016-12-21	Oculeve Inc	DEVICES AND METHODS FOR NASAL STIMULATION
AU2014268445B2 (en) *	2013-05-22	2019-03-07	Deep Brain Innovations LLC	Deep brain stimulator and method of use
CN111569263B (en)	2013-12-23	2024-04-26	脑深部创新有限责任公司	Programming system for deep brain stimulator systems
JP6604963B2 (en)	2014-02-25	2019-11-20	オキュリーブ，インコーポレイテッド	Polymer formulations for nasolacrimal gland stimulation
BR112016025203B1 (en)	2014-06-02	2022-09-06	Cala Health, Inc	TRANSCUTANEOUS SYSTEM TO TREAT A PATIENT SUFFERING FROM TREMOR
CA2956176A1 (en)	2014-07-25	2016-01-28	Oculeve, Inc.	Stimulation patterns for treating dry eye
AU2015335772B2 (en)	2014-10-22	2020-07-09	Oculeve, Inc.	Contact lens for increasing tear production
JP6735742B2 (en)	2014-10-22	2020-08-05	オキュリーブ，インコーポレイテッド	Stimulator and method for the treatment of dry eye
US10207108B2 (en)	2014-10-22	2019-02-19	Oculeve, Inc.	Implantable nasal stimulator systems and methods
DE102014117429A1 (en) *	2014-11-27	2016-06-02	Forschungszentrum Jülich GmbH	Apparatus and method for effective invasive neurostimulation by means of varying stimulus sequences
CN107847180A (en) *	2015-05-08	2018-03-27	杜克大学	spinal cord stimulation system and method
CN112914514B (en)	2015-06-10	2024-12-13	卡拉健康公司	Systems and methods for peripheral nerve stimulation to treat tremor using a detachable treatment and monitoring unit
US10335601B2 (en)	2015-07-30	2019-07-02	Boston Scientific Neuromodulation Corporation	User interface for custom patterned electrical stimulation
CN108135537B (en)	2015-07-31	2021-11-16	卡拉健康公司	Systems, devices and methods for treating osteoarthritis
EP3352843B1 (en)	2015-09-23	2021-06-23	Cala Health, Inc.	Device for peripheral nerve stimulation in the finger to treat hand tremors
WO2017066187A1 (en)	2015-10-15	2017-04-20	Boston Scientific Neuromodulation Corporation	User interface for neurostimulation waveform composition
US10426958B2 (en)	2015-12-04	2019-10-01	Oculeve, Inc.	Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
US10391313B2 (en)	2015-12-04	2019-08-27	Boston Scientific Neuromodulation Corporation	Systems and methods for the development of therapy paradigms for neurological treatments
US11344722B2 (en)	2016-01-21	2022-05-31	Cala Health, Inc.	Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US10252048B2 (en)	2016-02-19	2019-04-09	Oculeve, Inc.	Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
US10918864B2 (en)	2016-05-02	2021-02-16	Oculeve, Inc.	Intranasal stimulation for treatment of meibomian gland disease and blepharitis
US12233265B2 (en)	2016-08-25	2025-02-25	Cala Health, Inc.	Systems and methods for treating cardiac dysfunction through peripheral nerve stimulation
RU2019118600A (en)	2016-12-02	2021-01-11	Окулив, Инк.	APPARATUS AND METHOD FOR MAKING DRY EYE SYNDROME PREDICTION AND TREATMENT RECOMMENDATIONS
US11331480B2 (en)	2017-04-03	2022-05-17	Cala Health, Inc.	Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
EP3740274A4 (en)	2018-01-17	2021-10-27	Cala Health, Inc.	SYSTEMS AND METHODS OF TREATMENT OF INFLAMMATORY INTESTINAL DISEASE BY STIMULATION OF THE PERIPHERAL NERVE
WO2019246561A1 (en) *	2018-06-22	2019-12-26	The Board Of Trustees Of The Leland Stanford Junior University	Effective invasive multichannel desynchronizing stimulation
US12251560B1 (en)	2019-08-13	2025-03-18	Cala Health, Inc.	Connection quality determination for wearable neurostimulation systems
US11890468B1 (en)	2019-10-03	2024-02-06	Cala Health, Inc.	Neurostimulation systems with event pattern detection and classification
US20230064864A1 (en) *	2020-01-15	2023-03-02	Carnegie Mellon University	Neuromodulation Using Electrical Stimulation
AU2024369331A1 (en) *	2023-10-25	2026-04-09	Boston Scientific Neuromodulation Corporation	Sensing configurations for non-uniform neurostimulation patterns

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Publication number	Priority date	Publication date	Assignee	Title
US3833005A (en) *	1971-07-26	1974-09-03	Medtronic Inc	Compared count digitally controlled pacemaker
US5018524A (en) *	1985-05-15	1991-05-28	Hansen Gu	Apparatus and method for generating vital information signals
US5095904A (en) *	1989-09-08	1992-03-17	Cochlear Pty. Ltd.	Multi-peak speech procession
US20100152807A1 (en) *	2008-10-03	2010-06-17	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders

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CN1003839B (en) *	1986-04-24	1989-04-12	顾涵森	Device and method for generating vital information signal
US6366813B1 (en) *	1998-08-05	2002-04-02	Dilorenzo Daniel J.	Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US7010351B2 (en) *	2000-07-13	2006-03-07	Northstar Neuroscience, Inc.	Methods and apparatus for effectuating a lasting change in a neural-function of a patient
DE10318071A1 (en) *	2003-04-17	2004-11-25	Forschungszentrum Jülich GmbH	Device for desynchronizing neuronal brain activity
WO2007080460A1 (en) *	2005-09-15	2007-07-19	Koninklijke Philips Electronics, N.V.	Apparatus and method for electrostimulation/sensing in vivo

2012
- 2012-10-11 EP EP12839657.9A patent/EP2766087A4/en not_active Ceased
- 2012-10-11 AU AU2012322739A patent/AU2012322739A1/en not_active Abandoned
- 2012-10-11 EP EP20175204.5A patent/EP3718596B1/en active Active
- 2012-10-11 CA CA3169207A patent/CA3169207A1/en active Pending
- 2012-10-11 CN CN201710058910.9A patent/CN106955417B/en not_active Expired - Fee Related
- 2012-10-11 CN CN201280049892.3A patent/CN103889503B/en not_active Expired - Fee Related
- 2012-10-11 EP EP18167953.1A patent/EP3372274B1/en active Active
- 2012-10-11 WO PCT/US2012/059787 patent/WO2013055940A2/en not_active Ceased
- 2012-10-11 CA CA2846639A patent/CA2846639C/en active Active
2017
- 2017-05-08 AU AU2017203037A patent/AU2017203037B2/en not_active Ceased
2019
- 2019-07-15 AU AU2019205970A patent/AU2019205970B2/en not_active Ceased
2021
- 2021-05-04 AU AU2021202778A patent/AU2021202778A1/en not_active Abandoned

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3833005A (en) *	1971-07-26	1974-09-03	Medtronic Inc	Compared count digitally controlled pacemaker
US5018524A (en) *	1985-05-15	1991-05-28	Hansen Gu	Apparatus and method for generating vital information signals
US5095904A (en) *	1989-09-08	1992-03-17	Cochlear Pty. Ltd.	Multi-peak speech procession
US20100152807A1 (en) *	2008-10-03	2010-06-17	Duke University	Non-regular electrical stimulation patterns for treating neurological disorders

Also Published As

Publication number	Publication date
AU2021202778A1 (en)	2021-05-27
EP3372274A1 (en)	2018-09-12
EP2766087A2 (en)	2014-08-20
CN103889503B (en)	2017-03-08
EP3718596A1 (en)	2020-10-07
WO2013055940A3 (en)	2014-05-30
WO2013055940A2 (en)	2013-04-18
AU2019205970B2 (en)	2021-02-04
CN106955417A (en)	2017-07-18
AU2017203037A1 (en)	2017-06-01
CA2846639A1 (en)	2013-04-18
CN103889503A (en)	2014-06-25
EP3718596B1 (en)	2023-06-28
CA3169207A1 (en)	2013-04-18
CN106955417B (en)	2021-08-20
EP3372274B1 (en)	2020-06-24
AU2019205970A1 (en)	2019-08-01
AU2012322739A1 (en)	2014-03-13
CA2846639C (en)	2022-10-18
AU2017203037B2 (en)	2019-04-18

Legal Events

Date	Code	Title	Description
2014-07-18	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2014-08-20	17P	Request for examination filed	Effective date: 20140327
2014-08-20	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2015-05-06	A4	Supplementary search report drawn up and despatched	Effective date: 20150407
2015-05-06	DAX	Request for extension of the european patent (deleted)
2015-05-06	RIC1	Information provided on ipc code assigned before grant	Ipc: A61N 1/00 20060101AFI20150330BHEP Ipc: A61N 1/36 20060101ALI20150330BHEP Ipc: A61N 1/05 20060101ALI20150330BHEP
2016-03-16	17Q	First examination report despatched	Effective date: 20160215
2018-02-26	REG	Reference to a national code	Ref country code: DE Ref legal event code: R003
2018-06-01	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2018-07-04	18R	Application refused	Effective date: 20180226

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