EP2819684A4 - USE OF CARAMBOLE EXTRACT AS A CPT-1 MODULATOR AND COMPOSITIONS THEREOF - Google Patents

USE OF CARAMBOLE EXTRACT AS A CPT-1 MODULATOR AND COMPOSITIONS THEREOF

Info

Publication number
EP2819684A4
EP2819684A4 EP12870254.5A EP12870254A EP2819684A4 EP 2819684 A4 EP2819684 A4 EP 2819684A4 EP 12870254 A EP12870254 A EP 12870254A EP 2819684 A4 EP2819684 A4 EP 2819684A4
Authority
EP
European Patent Office
Prior art keywords
carambole
cpt
modulator
extract
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP12870254.5A
Other languages
German (de)
French (fr)
Other versions
EP2819684A1 (en
Inventor
Cheng S Hwang
Sungham Yim
Uma Santhanam
John W Lyga
M Jean Paufique
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avon Products Inc
Original Assignee
Avon Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avon Products Inc filed Critical Avon Products Inc
Publication of EP2819684A1 publication Critical patent/EP2819684A1/en
Publication of EP2819684A4 publication Critical patent/EP2819684A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP12870254.5A 2012-02-29 2012-02-29 USE OF CARAMBOLE EXTRACT AS A CPT-1 MODULATOR AND COMPOSITIONS THEREOF Withdrawn EP2819684A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2012/027065 WO2013130056A1 (en) 2012-02-29 2012-02-29 Use of starfruit extract as a cpt-1 modulator and compositions thereof

Publications (2)

Publication Number Publication Date
EP2819684A1 EP2819684A1 (en) 2015-01-07
EP2819684A4 true EP2819684A4 (en) 2015-12-16

Family

ID=49083096

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12870254.5A Withdrawn EP2819684A4 (en) 2012-02-29 2012-02-29 USE OF CARAMBOLE EXTRACT AS A CPT-1 MODULATOR AND COMPOSITIONS THEREOF

Country Status (7)

Country Link
EP (1) EP2819684A4 (en)
JP (1) JP2015508815A (en)
CN (1) CN104125832A (en)
BR (1) BR112014019602A8 (en)
CA (1) CA2863591A1 (en)
MX (1) MX2014009188A (en)
WO (1) WO2013130056A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014019167A8 (en) * 2012-02-29 2017-07-11 Avon Prod Inc USE OF PALMITOYL TRANSFERASE-1 (CPT-1) CARNITINE MODULATORS TO TREAT SKIN CONDITION DEFINED BY EXCESSIVE OR INSUFFICIENT SUBCUTANEOUS LIPIDS AND TO REDUCE CELLULITE RECURRENCE, AS WELL AS COSMETIC COMPOSITIONS COMPRISING SUCH MODULATORS AND METHOD TO IDENTIFY THEM
WO2015041514A1 (en) * 2013-09-19 2015-03-26 Forest Research Institute Malaysia Averrhoa carambola extract and a method for producing the extract
KR102096204B1 (en) * 2019-05-31 2020-04-02 최명석 Localized fat destroying method and hypotonic solution for destroying localized fat
JP7724607B2 (en) * 2020-11-11 2025-08-18 ポーラ化成工業株式会社 Expression enhancer of intercellular adhesion molecules in lymphatic vessels
CN117919292B (en) * 2024-01-26 2025-02-07 广西中医药大学 A marigold extract and its application in preparing anti-prostate cancer drugs

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002226323A (en) * 2001-02-02 2002-08-14 Maruzen Pharmaceut Co Ltd Collagen production promoter, collagenase inhibitor, fibroblast proliferation agent, elastase inhibitor, estrogen-like agent, skin cosmetics and cosmetics
JP2002241296A (en) * 2001-02-13 2002-08-28 Maruzen Pharmaceut Co Ltd TESTOSTERONE 5alpha-REDUCTASE INHIBITOR, ANDROGEN RECEPTOR BINDING INHIBITOR, ANTIANDROGENIC AGENT, HAIR COSMETIC, PROSTATOMEGALY INHIBITOR AND HEALTH SUPPLEMENT
KR20080088800A (en) * 2007-03-30 2008-10-06 (주)아모레퍼시픽 Slimming cosmetic composition
WO2008147148A1 (en) * 2007-05-31 2008-12-04 Amorepacific Corporation Composition of skin external application containing ginseng fruit extracts
JP2009191039A (en) * 2008-02-15 2009-08-27 Maruzen Pharmaceut Co Ltd Hyaluronic acid synthase 3 mRNA expression promoter, aquaporin 3 mRNA expression promoter, serine palmitoyltransferase mRNA expression promoter and laminin 5 production promoter
JP2010178736A (en) * 2009-01-06 2010-08-19 Zenyaku Kogyo Kk Skin beauty-ameliorating agent, antioxidant, skin beauty-ameliorating composition, or cosmetic food/drink
US20110305781A1 (en) * 2010-06-11 2011-12-15 Avon Products, Inc. Use of Eclipta Prostrata and Other PPAR-GAMMA Inhibitors in Cosmetics and Compositions Thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4889068B2 (en) * 2001-04-02 2012-02-29 丸善製薬株式会社 Histamine release inhibitor, cyclic AMP phosphodiesterase inhibitor, active oxygen scavenger and radical scavenger
JP2003238379A (en) * 2002-02-08 2003-08-27 Maruzen Pharmaceut Co Ltd Skin care preparation and hair cosmetic
EP1720605A4 (en) * 2003-06-23 2007-10-24 Transpharma Medical Ltd Transdermal delivery system for cosmetic agents
JP2008520588A (en) * 2004-11-18 2008-06-19 ビオファーマコペ デジン アンテルナショナル インク． Plant extract and its dermatological usage
JP4822718B2 (en) * 2005-03-16 2011-11-24 丸善製薬株式会社 Novel C-glycoside compounds, collagen production promoters, skin cosmetics and cosmetic foods and drinks
FR2939316B1 (en) * 2008-12-05 2012-08-10 Limousine D Applic Biolog Ditesilab Soc Ind COSMETIC USE OF ACTIVATORS OF AUTOPHAGIA OF SKIN CELLS.
JP2011105703A (en) * 2009-10-21 2011-06-02 Taisho Pharmaceutical Co Ltd Lipid absorption inhibitor
JP4666537B1 (en) * 2010-01-21 2011-04-06 株式会社資生堂 Wrinkle improving beauty set and beauty method using the same
JP2011055837A (en) * 2010-10-25 2011-03-24 Maruzen Pharmaceut Co Ltd Food and drink for beautification

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002226323A (en) * 2001-02-02 2002-08-14 Maruzen Pharmaceut Co Ltd Collagen production promoter, collagenase inhibitor, fibroblast proliferation agent, elastase inhibitor, estrogen-like agent, skin cosmetics and cosmetics
JP2002241296A (en) * 2001-02-13 2002-08-28 Maruzen Pharmaceut Co Ltd TESTOSTERONE 5alpha-REDUCTASE INHIBITOR, ANDROGEN RECEPTOR BINDING INHIBITOR, ANTIANDROGENIC AGENT, HAIR COSMETIC, PROSTATOMEGALY INHIBITOR AND HEALTH SUPPLEMENT
KR20080088800A (en) * 2007-03-30 2008-10-06 (주)아모레퍼시픽 Slimming cosmetic composition
WO2008147148A1 (en) * 2007-05-31 2008-12-04 Amorepacific Corporation Composition of skin external application containing ginseng fruit extracts
JP2009191039A (en) * 2008-02-15 2009-08-27 Maruzen Pharmaceut Co Ltd Hyaluronic acid synthase 3 mRNA expression promoter, aquaporin 3 mRNA expression promoter, serine palmitoyltransferase mRNA expression promoter and laminin 5 production promoter
JP2010178736A (en) * 2009-01-06 2010-08-19 Zenyaku Kogyo Kk Skin beauty-ameliorating agent, antioxidant, skin beauty-ameliorating composition, or cosmetic food/drink
US20110305781A1 (en) * 2010-06-11 2011-12-15 Avon Products, Inc. Use of Eclipta Prostrata and Other PPAR-GAMMA Inhibitors in Cosmetics and Compositions Thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE GNPD [online] MINTEL; 1 August 2009 (2009-08-01), ALOE-HA ENTERPRISES: "Pear Hibiscus Firming Body Lotion", XP002749429, Database accession no. 1162634 *
DATABASE GNPD [online] MINTEL; 1 September 2010 (2010-09-01), B&C LABORATORIES: "Vecua Clay Condition Mask IV", XP002749430, Database accession no. 1485113 *
GHEEWALA PAYAL ET AL: "PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF AVERRHOA CARAMBOLA LINN: AN OVERVIEW", 1 January 2012 (2012-01-01), XP055224070, Retrieved from the Internet <URL:http://www.irjponline.com/admin/php/uploads/796_pdf.pdf> [retrieved on 20151028] *
J IDKOWIAK-BALDYS ET AL: "Modulation of CPT-1 expression in primary human subcutaneous adipocytes with starfruit (Averrhoa carambola) leaf extract", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 132, no. Suppl. 1, 348, 1 May 2012 (2012-05-01) - 12 May 2012 (2012-05-12), US, pages S59, XP055162598, ISSN: 0022-202X, DOI: 10.1038/jid.2012.83 *
MONICA OTTAVIANI ET AL: "Lipid Mediators in Acne", MEDIATORS OF INFLAMMATION, vol. 10, no. 4, 1 January 2010 (2010-01-01), pages 169 - 6, XP055157063, ISSN: 0962-9351, DOI: 10.1111/j.1365-2133.2006.07671.x *
See also references of WO2013130056A1 *

Also Published As

Publication number Publication date
BR112014019602A2 (en) 2017-06-20
JP2015508815A (en) 2015-03-23
WO2013130056A1 (en) 2013-09-06
EP2819684A1 (en) 2015-01-07
MX2014009188A (en) 2014-08-27
BR112014019602A8 (en) 2017-07-11
CA2863591A1 (en) 2013-09-06
CN104125832A (en) 2014-10-29

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Legal Events

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AX Request for extension of the european patent

Extension state: BA ME

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: AVON PRODUCTS, INC.

DAX Request for extension of the european patent (deleted)
RA4 Supplementary search report drawn up and despatched (corrected)

Effective date: 20151117

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 8/97 20060101AFI20151106BHEP

Ipc: A61K 36/185 20060101ALI20151106BHEP

Ipc: A61Q 19/06 20060101ALI20151106BHEP

Ipc: A61Q 19/00 20060101ALI20151106BHEP

17Q First examination report despatched

Effective date: 20170719

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Effective date: 20171130