EP2825201A4 - FILAMENTOUS BACTERIOPHAGE AS A MODULATOR OF ANGIOGENESIS - Google Patents

FILAMENTOUS BACTERIOPHAGE AS A MODULATOR OF ANGIOGENESIS

Info

Publication number: EP2825201A4
Authority: EP; European Patent Office
Prior art keywords: angiogenesis; modulator; filamentous bacteriophage; filamentous; bacteriophage
Prior art date: 2012-03-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP13761938.3A

Other languages

German (de)

French (fr)

Other versions

EP2825201A1 (en

Inventor

Beka Solomon

Eyal Dor-On

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ramot at Tel Aviv University Ltd

Original Assignee

Ramot at Tel Aviv University Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-03-15

Filing date

2013-03-15

Publication date

2015-12-09

2013-03-15 Application filed by Ramot at Tel Aviv University Ltd filed Critical Ramot at Tel Aviv University Ltd

2015-01-21 Publication of EP2825201A1 publication Critical patent/EP2825201A1/en

2015-12-09 Publication of EP2825201A4 publication Critical patent/EP2825201A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/14011—Details ssDNA Bacteriophages
- C12N2795/14111—Inoviridae
- C12N2795/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/14011—Details ssDNA Bacteriophages
- C12N2795/14111—Inoviridae
- C12N2795/14132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/14011—Details ssDNA Bacteriophages
- C12N2795/14111—Inoviridae
- C12N2795/14141—Use of virus, viral particle or viral elements as a vector
- C12N2795/14145—Special targeting system for viral vectors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/14011—Details ssDNA Bacteriophages
- C12N2795/14111—Inoviridae
- C12N2795/14151—Methods of production or purification of viral material

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Immunology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Oncology (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

EP13761938.3A 2012-03-15 2013-03-15 FILAMENTOUS BACTERIOPHAGE AS A MODULATOR OF ANGIOGENESIS Withdrawn EP2825201A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201261611297P	2012-03-15	2012-03-15
US201261715634P	2012-10-18	2012-10-18
PCT/US2013/032043 WO2013138716A1 (en)	2012-03-15	2013-03-15	The filamentous bacteriophage as an angiogenesis modulator

Publications (2)

Publication Number	Publication Date
EP2825201A1 EP2825201A1 (en)	2015-01-21
EP2825201A4 true EP2825201A4 (en)	2015-12-09

Family

ID=49161851

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP13761938.3A Withdrawn EP2825201A4 (en)	2012-03-15	2013-03-15	FILAMENTOUS BACTERIOPHAGE AS A MODULATOR OF ANGIOGENESIS

Country Status (2)

Country	Link
EP (1)	EP2825201A4 (en)
WO (1)	WO2013138716A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT201700009270A1 (en) *	2017-01-27	2018-07-27	Consiglio Naz Delle Ricerche Cnr	Phagic conjugates and their uses
KR20220069102A (en)	2019-10-01	2022-05-26	어댑티브 페이지 테라퓨틱스, 인크.	Purification method of bacteriophage particles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5096169B2 (en) *	2005-02-01	2012-12-12	ラモット・アット・テルアビブ・ユニバーシティ	Treatment of inflammation associated with amyloid deposits and brain inflammation associated with activated microglia
WO2006095345A2 (en) *	2005-03-08	2006-09-14	Ramot At Tel-Aviv University Ltd.	Targeted drug-carrying bacteriophages
WO2007053542A2 (en) *	2005-11-01	2007-05-10	Boston Life Sciences, Inc.	Methods and compositions for the prevention and regression of neovascularization
MX2008010612A (en) *	2006-02-15	2009-03-20	Ramot At Tel Aviv University	Filamentous bacteriophage displaying protein as a binder of antibodies and immunocomplexes for delivery to the brain.
GB0703369D0 (en) *	2007-02-21	2007-03-28	Health Prot Agency	Compositions Comprising Capsular Polysaccharides and Their Use as Vaccines

2013
- 2013-03-15 EP EP13761938.3A patent/EP2825201A4/en not_active Withdrawn
- 2013-03-15 WO PCT/US2013/032043 patent/WO2013138716A1/en not_active Ceased

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BORATYNSKI JANUSZ ET AL: "Preparation of endotoxin-free bacteriophages", CELLULAR & MOLECULAR BIOLOGY LETTERS, UNIVERSITY OF WROCAW. INSTITUTE OF BIOCHEMISTRY, WROCAW; PL, PL, vol. 9, no. 2, 1 January 2004 (2004-01-01), pages 253 - 259, XP002485107, ISSN: 1425-8153 *
DABROWSKA K ET AL: "Activity of bacteriophages in murine tumor models depends on the route of phage administration", ONCOLOGY RESEARCH, PERGAMON PRESS, NEW YORK, NY, US, vol. 15, no. 4, 1 January 2005 (2005-01-01), pages 183 - 187, XP008120418, ISSN: 0965-0407 *
DABROWSKA KRYSTYNA ET AL: "The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration", BMC MICROBIOLOGY, BIOMED CENTRAL LTD, GB, vol. 9, no. 1, 20 January 2009 (2009-01-20), pages 13, XP021048179, ISSN: 1471-2180, DOI: 10.1186/1471-2180-9-13 *
JESSICA I. LUNDIN ET AL: "Endotoxin and Cancer", ENVIRONMENTAL HEALTH PERSPECTIVES SUPPLEMENTS, vol. 117, no. 9, 1 September 2009 (2009-09-01), US, pages 1344 - 1350, XP055221367, ISSN: 1078-0475, DOI: 10.1289/ehp.0800439 *
PAULINA BUDYNEK ET AL: "Bacteriophages and cancer", ARCHIVES OF MICROBIOLOGY, SPRINGER, BERLIN, DE, vol. 192, no. 5, 16 March 2010 (2010-03-16), pages 315 - 320, XP019798350, ISSN: 1432-072X *
See also references of WO2013138716A1 *
TOURNAIRE R ET AL: "A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor", EMBO REPORTS, vol. 5, no. 3, 1 January 2004 (2004-01-01), pages 262 - 267, XP002321017, DOI: 10.1038/SJ.EMBOR.7400100 *

Also Published As

Publication number	Publication date
EP2825201A1 (en)	2015-01-21
WO2013138716A1 (en)	2013-09-19

Legal Events

Date	Code	Title	Description
2014-12-19	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2015-01-21	17P	Request for examination filed	Effective date: 20140902
2015-01-21	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2015-01-21	AX	Request for extension of the european patent	Extension state: BA ME
2015-06-24	DAX	Request for extension of the european patent (deleted)
2015-12-09	RA4	Supplementary search report drawn up and despatched (corrected)	Effective date: 20151106
2015-12-09	RIC1	Information provided on ipc code assigned before grant	Ipc: C12N 7/00 20060101ALI20151102BHEP Ipc: A61K 39/395 20060101AFI20151102BHEP Ipc: A61P 35/00 20060101ALI20151102BHEP Ipc: A61K 35/76 20150101ALI20151102BHEP Ipc: C07K 14/005 20060101ALI20151102BHEP Ipc: A61P 31/00 20060101ALI20151102BHEP
2017-02-10	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN
2017-03-15	18W	Application withdrawn	Effective date: 20170202

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