EP2977044A4 - TWO PHASE SEPARATION TYPE OCULAR DROP CONTAINING SQUALANE - Google Patents

TWO PHASE SEPARATION TYPE OCULAR DROP CONTAINING SQUALANE

Info

Publication number
EP2977044A4
EP2977044A4 EP14767461.8A EP14767461A EP2977044A4 EP 2977044 A4 EP2977044 A4 EP 2977044A4 EP 14767461 A EP14767461 A EP 14767461A EP 2977044 A4 EP2977044 A4 EP 2977044A4
Authority
EP
European Patent Office
Prior art keywords
phase separation
separation type
drop containing
containing squalane
type ocular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP14767461.8A
Other languages
German (de)
French (fr)
Other versions
EP2977044A1 (en
EP2977044B1 (en
Inventor
Shirou Sawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Publication of EP2977044A1 publication Critical patent/EP2977044A1/en
Publication of EP2977044A4 publication Critical patent/EP2977044A4/en
Application granted granted Critical
Publication of EP2977044B1 publication Critical patent/EP2977044B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Dispersion Chemistry (AREA)
EP14767461.8A 2013-03-19 2014-03-18 Two-layer separation-type eye drop containing squalane Not-in-force EP2977044B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013055929 2013-03-19
PCT/JP2014/057211 WO2014148450A1 (en) 2013-03-19 2014-03-18 Two-layer separation-type eye drop containing squalane

Publications (3)

Publication Number Publication Date
EP2977044A1 EP2977044A1 (en) 2016-01-27
EP2977044A4 true EP2977044A4 (en) 2016-09-14
EP2977044B1 EP2977044B1 (en) 2018-01-31

Family

ID=51580129

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14767461.8A Not-in-force EP2977044B1 (en) 2013-03-19 2014-03-18 Two-layer separation-type eye drop containing squalane

Country Status (6)

Country Link
US (2) US9907750B2 (en)
EP (1) EP2977044B1 (en)
JP (1) JP6215306B2 (en)
KR (1) KR102218491B1 (en)
CN (1) CN105050590B (en)
WO (1) WO2014148450A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2704918T3 (en) * 2016-04-15 2019-03-20 Dr Gerhard Mann Chem Pharm Fabrik Gmbh Stable ophthalmic composition in storage
EP3468530A4 (en) 2016-06-10 2020-03-11 Clarity Cosmetics Inc. NON-COMEDOGENOUS HAIR AND SCALP CARE FORMULATIONS AND METHOD OF USE

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1782801A1 (en) * 2004-08-27 2007-05-09 Senju Pharmaceutical Co., Ltd. Eyewash liquid for dry eye therapy
EP2070518A2 (en) * 2006-07-25 2009-06-17 Osmotica Corp. Ophthalmic solutions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10218760A (en) 1997-02-04 1998-08-18 Nobel Igaku Kenkyusho:Kk Eye drop with small amount of oil added for treating dry eye
JPWO2006009101A1 (en) 2004-07-21 2008-05-01 千寿製薬株式会社 Contact lens mounting solution
JP5549045B2 (en) 2006-01-13 2014-07-16 大正製薬株式会社 Aqueous eye drops for prevention or improvement of hyperevaporation type dry eye
US9096819B2 (en) * 2008-01-31 2015-08-04 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1782801A1 (en) * 2004-08-27 2007-05-09 Senju Pharmaceutical Co., Ltd. Eyewash liquid for dry eye therapy
EP2070518A2 (en) * 2006-07-25 2009-06-17 Osmotica Corp. Ophthalmic solutions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2014148450A1 *

Also Published As

Publication number Publication date
JPWO2014148450A1 (en) 2017-02-16
KR102218491B1 (en) 2021-02-19
CN105050590A (en) 2015-11-11
US9907750B2 (en) 2018-03-06
EP2977044A1 (en) 2016-01-27
KR20150133173A (en) 2015-11-27
EP2977044B1 (en) 2018-01-31
CN105050590B (en) 2018-01-19
JP6215306B2 (en) 2017-10-18
US10568833B2 (en) 2020-02-25
US20180140548A1 (en) 2018-05-24
US20160067181A1 (en) 2016-03-10
WO2014148450A1 (en) 2014-09-25

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