EP3248544A4 - Device for measuring concentration of substance in blood, and method for measuring concentration of substance in blood - Google Patents
Device for measuring concentration of substance in blood, and method for measuring concentration of substance in blood Download PDFInfo
- Publication number
- EP3248544A4 EP3248544A4 EP16740127.2A EP16740127A EP3248544A4 EP 3248544 A4 EP3248544 A4 EP 3248544A4 EP 16740127 A EP16740127 A EP 16740127A EP 3248544 A4 EP3248544 A4 EP 3248544A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- blood
- substance
- measuring concentration
- concentration
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
-
- G—PHYSICS
- G02—OPTICS
- G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
- G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
- G02F1/35—Non-linear optics
- G02F1/3501—Constructional details or arrangements of non-linear optical devices, e.g. shape of non-linear crystals
-
- G—PHYSICS
- G02—OPTICS
- G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
- G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
- G02F1/35—Non-linear optics
- G02F1/39—Non-linear optics for parametric generation or amplification of light, infrared or ultraviolet waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/30—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
- A61B2090/306—Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure using optical fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B90/361—Image-producing devices, e.g. surgical cameras
- A61B2090/3614—Image-producing devices, e.g. surgical cameras using optical fibre
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
-
- G—PHYSICS
- G02—OPTICS
- G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
- G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
- G02F1/35—Non-linear optics
- G02F1/3501—Constructional details or arrangements of non-linear optical devices, e.g. shape of non-linear crystals
- G02F1/3507—Arrangements comprising two or more nonlinear optical devices
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/14—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range characterised by the material used as the active medium
- H01S3/16—Solid materials
- H01S3/1601—Solid materials characterised by an active (lasing) ion
- H01S3/1603—Solid materials characterised by an active (lasing) ion rare earth
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/14—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range characterised by the material used as the active medium
- H01S3/16—Solid materials
- H01S3/163—Solid materials characterised by a crystal matrix
- H01S3/164—Solid materials characterised by a crystal matrix garnet
- H01S3/1643—YAG
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/14—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range characterised by the material used as the active medium
- H01S3/22—Gases
- H01S3/223—Gases the active gas being polyatomic, i.e. containing two or more atoms
- H01S3/2232—Carbon dioxide (CO2) or monoxide [CO]
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nonlinear Science (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Emergency Medicine (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015009504 | 2015-01-21 | ||
| PCT/JP2016/051339 WO2016117520A1 (en) | 2015-01-21 | 2016-01-19 | Device for measuring concentration of substance in blood, and method for measuring concentration of substance in blood |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP3248544A1 EP3248544A1 (en) | 2017-11-29 |
| EP3248544A4 true EP3248544A4 (en) | 2018-09-05 |
| EP3248544B1 EP3248544B1 (en) | 2021-12-08 |
Family
ID=56417064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP16740127.2A Active EP3248544B1 (en) | 2015-01-21 | 2016-01-19 | Device for measuring concentration of substance in blood, and method for measuring concentration of substance in blood |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10806385B2 (en) |
| EP (1) | EP3248544B1 (en) |
| JP (3) | JP6415606B2 (en) |
| CN (1) | CN107427266B (en) |
| WO (1) | WO2016117520A1 (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN118099918A (en) * | 2017-09-05 | 2024-05-28 | 国立研究开发法人量子科学技术研究开发机构 | Light source and measuring device |
| EP3477278B1 (en) * | 2017-10-27 | 2020-04-22 | Humboldt-Universität zu Berlin | Photoacoustics method with a measuring light comprising a predetermined wavelength range for determining the properties of an inhomogeneous sample |
| WO2019110084A1 (en) * | 2017-12-04 | 2019-06-13 | Diamontech Gmbh | Device and method for analysing a substance |
| US20210076991A1 (en) * | 2018-01-16 | 2021-03-18 | The Regents Of The University Of California | In-situ sweat rate monitoring for normalization of sweat analyte concentrations |
| CN112384786B (en) * | 2018-05-09 | 2024-08-23 | 国立研究开发法人量子科学技术研究开发机构 | Tissue identification device, tissue identification system, tissue identification method and recording medium |
| CN110514617A (en) * | 2018-05-22 | 2019-11-29 | 泰科电子(上海)有限公司 | Concentration detection device, concentration monitoring device and solar water heater |
| JP7080480B2 (en) * | 2018-07-19 | 2022-06-06 | 有限会社ティ・エス・イー | Non-invasive blood sugar meter |
| WO2020017028A1 (en) * | 2018-07-20 | 2020-01-23 | 桐生電子開発合同会社 | Nondestructive inspection device |
| WO2020121073A1 (en) * | 2018-12-14 | 2020-06-18 | Ecole Polytechnique Federale De Lausanne (Epfl) | Non-invasive glucose sensor |
| WO2020130571A1 (en) * | 2018-12-19 | 2020-06-25 | 전자부품연구원 | Non-invasive blood testing device and method |
| KR102727114B1 (en) * | 2019-02-01 | 2024-11-06 | 현대자동차주식회사 | Non-invasive optical internal substance detector |
| KR102765475B1 (en) | 2019-04-10 | 2025-02-07 | 삼성전자주식회사 | Apparatus and method for estimating bio-information |
| CN112641443A (en) * | 2019-10-12 | 2021-04-13 | 潍坊学院 | Device for nondestructive testing of glucose in subcutaneous tissue fluid |
| JP7439456B2 (en) * | 2019-10-28 | 2024-02-28 | 株式会社リコー | Biological information measuring device and biological information measuring method |
| DE112020006830T5 (en) * | 2020-03-04 | 2022-12-15 | Mitsubishi Electric Corporation | MEASURING DEVICE FOR BIOLOGICAL COMPONENTS |
| JP7729075B2 (en) * | 2020-07-30 | 2025-08-26 | 株式会社リコー | Measuring equipment |
| WO2022023846A1 (en) * | 2020-07-30 | 2022-02-03 | Ricoh Company, Ltd. | Measuring apparatus |
| JP7620337B2 (en) * | 2020-09-30 | 2025-01-23 | ライトタッチテクノロジー株式会社 | Blood substance concentration measuring device and blood substance concentration measuring method |
| CN112683851A (en) * | 2021-03-22 | 2021-04-20 | 宁波普瑞柏生物技术股份有限公司 | Protein concentration detection and analysis method, device and application thereof |
| KR102511907B1 (en) * | 2021-05-26 | 2023-03-20 | 건국대학교 글로컬산학협력단 | Non-invasive biomaterial sugar concentration measurement system and method using optical module |
| CN113675719A (en) * | 2021-07-16 | 2021-11-19 | 西安电子科技大学 | A tunable long-wave mid-infrared ultrafast laser light source device |
| JP7541301B2 (en) * | 2021-08-25 | 2024-08-28 | ライトタッチテクノロジー株式会社 | Blood substance concentration measuring device, blood substance concentration measuring method and program |
| DE102021132135A1 (en) * | 2021-12-07 | 2023-06-07 | OSRAM Opto Semiconductors Gesellschaft mit beschränkter Haftung | PROCEDURE FOR DETERMINING A SUBSTANCE CONCENTRATION AND DETECTOR ARRANGEMENT |
| WO2023157164A1 (en) * | 2022-02-17 | 2023-08-24 | 三菱電機株式会社 | Non-invasive substance analysis device |
| WO2023167804A1 (en) | 2022-03-01 | 2023-09-07 | Illumina, Inc. | Analog circuit to compensate bias offset in amplifier array |
| EP4403107A4 (en) * | 2022-04-06 | 2025-02-26 | Light Touch Technology Incorporated | BLOOD SUBSTANCE CONCENTRATION MEASURING DEVICE, BLOOD SUBSTANCE CONCENTRATION MEASURING METHOD, AND PROGRAM |
| EP4364660A4 (en) * | 2022-09-17 | 2025-02-26 | Light Touch Technology Incorporated | BLOOD SUBSTANCE CONCENTRATION MEASURING DEVICE, BLOOD SUBSTANCE CONCENTRATION MEASURING METHOD, AND PROGRAM |
| JP2024112539A (en) | 2023-02-08 | 2024-08-21 | 株式会社東芝 | Sensing system and reflective optical element |
| WO2025079663A1 (en) | 2023-10-11 | 2025-04-17 | ライトタッチテクノロジー株式会社 | Blood substance concentration measurement device, blood substance concentration measurement method, and program |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4169676A (en) * | 1976-02-20 | 1979-10-02 | Nils Kaiser | Method for determining the contents of metabolic products in the blood |
| JPH11178799A (en) * | 1997-12-22 | 1999-07-06 | Matsushita Electric Works Ltd | Vital method and device for analyzing superficial tissue of organism |
| US20040024541A1 (en) * | 2001-08-28 | 2004-02-05 | Shinji Uchida | Apparatus for measuring information on particular component |
| US20070213607A1 (en) * | 2006-03-07 | 2007-09-13 | Andreas Mandelis | Non-invasive biothermophotonic sensor for blood glucose monitoring |
| US20120088486A1 (en) * | 2009-04-07 | 2012-04-12 | Messerchmidt Robert G | Peri-critical reflection spectroscopy devices, systems, and methods |
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-
2016
- 2016-01-19 WO PCT/JP2016/051339 patent/WO2016117520A1/en not_active Ceased
- 2016-01-19 CN CN201680017373.7A patent/CN107427266B/en active Active
- 2016-01-19 JP JP2016570633A patent/JP6415606B2/en active Active
- 2016-01-19 US US15/545,661 patent/US10806385B2/en active Active
- 2016-01-19 EP EP16740127.2A patent/EP3248544B1/en active Active
-
2018
- 2018-10-02 JP JP2018187388A patent/JP2018199080A/en active Pending
-
2020
- 2020-09-29 US US17/035,751 patent/US11412963B2/en active Active
- 2020-11-13 JP JP2020189743A patent/JP2021037321A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4169676A (en) * | 1976-02-20 | 1979-10-02 | Nils Kaiser | Method for determining the contents of metabolic products in the blood |
| JPH11178799A (en) * | 1997-12-22 | 1999-07-06 | Matsushita Electric Works Ltd | Vital method and device for analyzing superficial tissue of organism |
| US20040024541A1 (en) * | 2001-08-28 | 2004-02-05 | Shinji Uchida | Apparatus for measuring information on particular component |
| US20070213607A1 (en) * | 2006-03-07 | 2007-09-13 | Andreas Mandelis | Non-invasive biothermophotonic sensor for blood glucose monitoring |
| US20120088486A1 (en) * | 2009-04-07 | 2012-04-12 | Messerchmidt Robert G | Peri-critical reflection spectroscopy devices, systems, and methods |
Non-Patent Citations (4)
| Title |
|---|
| K. L. VODOPYANOV ET AL: "Grating tunable 4 - 14 m GaAs optical parametric oscillator pumped at 3 m", OPTICS EXPRESS, vol. 22, no. 4, 14 February 2014 (2014-02-14), pages 4131, XP055496459, DOI: 10.1364/OE.22.004131 * |
| MARTINA MEINKE ET AL: "Two-wavelength carbon dioxide laser application for in-vitro blood glucose measurements", INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, vol. 13, no. 1, 1 January 2008 (2008-01-01), PO Box 10 Bellingham WA 98227-0010 USA, pages 014021 - 1, XP055496184, ISSN: 1083-3668, DOI: 10.1117/1.2870093 * |
| See also references of WO2016117520A1 * |
| SONGLIN YU ET AL: "In vitro glucose measurement using tunable mid-infrared laser spectroscopy combined with fiber-optic sensor", BIOMEDICAL OPTICS EXPRESS, vol. 5, no. 1, 17 December 2013 (2013-12-17), United States, pages 275, XP055467036, ISSN: 2156-7085, DOI: 10.1364/BOE.5.000275 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3248544A1 (en) | 2017-11-29 |
| CN107427266B (en) | 2021-12-03 |
| HK1243902A1 (en) | 2018-07-27 |
| WO2016117520A1 (en) | 2016-07-28 |
| US20210038125A1 (en) | 2021-02-11 |
| JP2018199080A (en) | 2018-12-20 |
| JP6415606B2 (en) | 2018-10-31 |
| EP3248544B1 (en) | 2021-12-08 |
| US20180000386A1 (en) | 2018-01-04 |
| JP2021037321A (en) | 2021-03-11 |
| US10806385B2 (en) | 2020-10-20 |
| US11412963B2 (en) | 2022-08-16 |
| JPWO2016117520A1 (en) | 2017-10-26 |
| CN107427266A (en) | 2017-12-01 |
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