EP3387431A4 - SYSTEMS, METHODS, AND COMPOSITIONS FOR IMPROVING THE SPECIFICITY OF HYBRIDIZATION OF NUCLEIC ACIDS - Google Patents

SYSTEMS, METHODS, AND COMPOSITIONS FOR IMPROVING THE SPECIFICITY OF HYBRIDIZATION OF NUCLEIC ACIDS Download PDF

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Publication number
EP3387431A4
EP3387431A4 EP16874070.2A EP16874070A EP3387431A4 EP 3387431 A4 EP3387431 A4 EP 3387431A4 EP 16874070 A EP16874070 A EP 16874070A EP 3387431 A4 EP3387431 A4 EP 3387431A4
Authority
EP
European Patent Office
Prior art keywords
hybridization
specificity
compositions
improving
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16874070.2A
Other languages
German (de)
French (fr)
Other versions
EP3387431A1 (en
Inventor
Michael Okura
Michael D. Okura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP3387431A1 publication Critical patent/EP3387431A1/en
Publication of EP3387431A4 publication Critical patent/EP3387431A4/en
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP16874070.2A 2015-12-11 2016-12-12 SYSTEMS, METHODS, AND COMPOSITIONS FOR IMPROVING THE SPECIFICITY OF HYBRIDIZATION OF NUCLEIC ACIDS Withdrawn EP3387431A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562266143P 2015-12-11 2015-12-11
PCT/US2016/066227 WO2017100792A1 (en) 2015-12-11 2016-12-12 Systems, methods and compositions for enhancing the specificity of nucleic acid hybridization

Publications (2)

Publication Number Publication Date
EP3387431A1 EP3387431A1 (en) 2018-10-17
EP3387431A4 true EP3387431A4 (en) 2019-05-01

Family

ID=59013433

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16874070.2A Withdrawn EP3387431A4 (en) 2015-12-11 2016-12-12 SYSTEMS, METHODS, AND COMPOSITIONS FOR IMPROVING THE SPECIFICITY OF HYBRIDIZATION OF NUCLEIC ACIDS

Country Status (2)

Country Link
EP (1) EP3387431A4 (en)
WO (1) WO2017100792A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12385161B2 (en) 2018-06-06 2025-08-12 Ramot At Tel-Aviv University Ltd. Multi-sample array chip for DNA modification quantification
CN109116015B (en) * 2018-09-27 2021-07-09 深圳大学 A method for making and using a blocking-free ELISA plate
CN113150680B (en) * 2019-12-25 2023-11-24 南京金斯瑞生物科技有限公司 Chip coating, preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006675A2 (en) * 2001-07-11 2003-01-23 Baylor College Of Medicine Methods and devices based upon a novel form of nucleic acid duplex on a surface
WO2012142346A1 (en) * 2011-04-12 2012-10-18 Real-Time Genomics, Llc Method and apparatus for high accuracy genomic analysis platform utilizing hybridization and enhanced dissociation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006675A2 (en) * 2001-07-11 2003-01-23 Baylor College Of Medicine Methods and devices based upon a novel form of nucleic acid duplex on a surface
WO2012142346A1 (en) * 2011-04-12 2012-10-18 Real-Time Genomics, Llc Method and apparatus for high accuracy genomic analysis platform utilizing hybridization and enhanced dissociation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ARNOLD VAINRUB ET AL: "Surface electrostatic effects in oligonucleotide microarrays: Control and optimization of binding thermodynamics", BIOPOLYMERS, 1 February 2003 (2003-02-01), New York, pages 265 - 270, XP055133705, Retrieved from the Internet <URL:http://onlinelibrary.wiley.com/doi/10.1002/bip.10271/abstract> DOI: 10.1002/bip.10271 *
See also references of WO2017100792A1 *

Also Published As

Publication number Publication date
EP3387431A1 (en) 2018-10-17
WO2017100792A1 (en) 2017-06-15

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