EP3419661A4 - METHOD AND COMPOSITION FOR TREATING CANCER OR SKIN INJURY USING A VACCINE - Google Patents

METHOD AND COMPOSITION FOR TREATING CANCER OR SKIN INJURY USING A VACCINE Download PDF

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Publication number
EP3419661A4
EP3419661A4 EP17757336.7A EP17757336A EP3419661A4 EP 3419661 A4 EP3419661 A4 EP 3419661A4 EP 17757336 A EP17757336 A EP 17757336A EP 3419661 A4 EP3419661 A4 EP 3419661A4
Authority
EP
European Patent Office
Prior art keywords
vaccine
composition
treating cancer
skin injury
injury
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17757336.7A
Other languages
German (de)
French (fr)
Other versions
EP3419661A1 (en
Inventor
Tim Ioannides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hpvvax LLC
Original Assignee
Hpvvax LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hpvvax LLC filed Critical Hpvvax LLC
Publication of EP3419661A1 publication Critical patent/EP3419661A1/en
Publication of EP3419661A4 publication Critical patent/EP3419661A4/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Anesthesiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
EP17757336.7A 2016-02-27 2017-02-24 METHOD AND COMPOSITION FOR TREATING CANCER OR SKIN INJURY USING A VACCINE Pending EP3419661A4 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662300785P 2016-02-27 2016-02-27
US201662328487P 2016-04-27 2016-04-27
US201662338183P 2016-05-18 2016-05-18
US201762444576P 2017-01-10 2017-01-10
US201762455434P 2017-02-06 2017-02-06
PCT/US2017/019433 WO2017147475A1 (en) 2016-02-27 2017-02-24 Method and composition for treating cancer or skin lesion using a vaccine

Publications (2)

Publication Number Publication Date
EP3419661A1 EP3419661A1 (en) 2019-01-02
EP3419661A4 true EP3419661A4 (en) 2019-10-23

Family

ID=59686556

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17757336.7A Pending EP3419661A4 (en) 2016-02-27 2017-02-24 METHOD AND COMPOSITION FOR TREATING CANCER OR SKIN INJURY USING A VACCINE

Country Status (16)

Country Link
EP (1) EP3419661A4 (en)
JP (3) JP2019506435A (en)
KR (1) KR102873848B1 (en)
CN (1) CN108883168A (en)
AU (1) AU2017223970B2 (en)
BR (1) BR112018067550A2 (en)
CA (1) CA3015519A1 (en)
CL (1) CL2018002438A1 (en)
CO (1) CO2018009205A2 (en)
HK (1) HK1256935A1 (en)
IL (1) IL261340B2 (en)
MX (1) MX2018010338A (en)
MY (1) MY194694A (en)
SG (1) SG11201807080UA (en)
WO (1) WO2017147475A1 (en)
ZA (1) ZA201805679B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114127095B (en) * 2019-07-19 2024-04-09 神州细胞工程有限公司 Chimeric human papillomavirus type 11 L1 protein
PL4225351T1 (en) * 2020-10-12 2023-12-11 Hpvvax, Llc Composition and method for treating cancer using a vaccine as a first therapueutic active ingredient in combination with a second active ingredient
KR20250089555A (en) * 2022-10-31 2025-06-18 파이로자스 인크 Immunotherapeutic compositions and methods of use

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002087614A2 (en) * 2001-04-27 2002-11-07 Glaxosmithkline Biologicals S.A. Multivalent vaccine comprising an hiv antigen and an hsv antigen and/or an hpv antigen
WO2003078455A2 (en) * 2002-03-18 2003-09-25 Glaxosmithkline Biologicals Sa Virus like particle from papillomavirus and their use in vaccine
WO2003077942A2 (en) * 2002-03-18 2003-09-25 Glaxosmithkline Biologicals Sa Virus-like particles of human papillomavirus
WO2010120266A1 (en) * 2009-04-13 2010-10-21 Inserm, Institut National De La Sante Et De La Recherche Medicale Hpv particles and uses thereof
US20130064849A1 (en) * 2011-07-14 2013-03-14 The Board Of Regents Of The University Of Texas Methods to treat and prevent cardiovascular disease using human papillomavirus vaccines
US20130251782A1 (en) * 2012-03-22 2013-09-26 Leo Laboratories Limited Topical application of ingenol mebutate with occlusion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101890160B (en) * 2009-04-28 2014-06-18 北京康乐卫士生物技术有限公司 Multivalent recombinant human papilloma virus vaccine and application thereof
CA2768172A1 (en) * 2009-06-25 2010-12-29 Glaxosmithkline Biologicals S.A. Novel compositions
JP2014516075A (en) * 2011-06-06 2014-07-07 シェブロン フィリップス ケミカル カンパニー エルピー Use of metallocene compounds for the treatment of cancer
WO2013139744A1 (en) * 2012-03-18 2013-09-26 Glaxosmithkline Biologicals S.A. Method of vaccination against human papillomavirus
US20140275082A1 (en) * 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
US9974849B2 (en) * 2013-10-13 2018-05-22 Bioventures, Llc Human Papilloma virus therapeutic vaccine
CN120939216A (en) * 2014-01-13 2025-11-14 贝勒研究院 New vaccines against HPV and HPV-related diseases
CN107001430A (en) * 2014-10-24 2017-08-01 哈普威克斯有限责任公司 Cancer and cutaneous lesions treatment

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002087614A2 (en) * 2001-04-27 2002-11-07 Glaxosmithkline Biologicals S.A. Multivalent vaccine comprising an hiv antigen and an hsv antigen and/or an hpv antigen
WO2003078455A2 (en) * 2002-03-18 2003-09-25 Glaxosmithkline Biologicals Sa Virus like particle from papillomavirus and their use in vaccine
WO2003077942A2 (en) * 2002-03-18 2003-09-25 Glaxosmithkline Biologicals Sa Virus-like particles of human papillomavirus
WO2010120266A1 (en) * 2009-04-13 2010-10-21 Inserm, Institut National De La Sante Et De La Recherche Medicale Hpv particles and uses thereof
US20130064849A1 (en) * 2011-07-14 2013-03-14 The Board Of Regents Of The University Of Texas Methods to treat and prevent cardiovascular disease using human papillomavirus vaccines
US20130251782A1 (en) * 2012-03-22 2013-09-26 Leo Laboratories Limited Topical application of ingenol mebutate with occlusion

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
A. SCHILLING ET AL: "Coadministration of a 9-Valent Human Papillomavirus Vaccine With Meningococcal and Tdap Vaccines", PEDIATRICS, vol. 136, no. 3, 1 September 2015 (2015-09-01), pages e563 - e572, XP055519294, ISSN: 0031-4005, DOI: 10.1542/peds.2014-4199 *
ANNA J. NICHOLS ET AL: "Combined Systemic and Intratumoral Administration of Human Papillomavirus Vaccine to Treat Multiple Cutaneous Basaloid Squamous Cell Carcinomas", JAMA DERMATOLOGY, vol. 154, no. 8, 1 August 2018 (2018-08-01), US, pages 927, XP055537673, ISSN: 2168-6068, DOI: 10.1001/jamadermatol.2018.1748 *
ANNA TADDIO ET AL: "A randomized controlled trial of analgesia during vaccination in adults", VACCINE, vol. 28, no. 32, 1 July 2010 (2010-07-01), AMSTERDAM, NL, pages 5365 - 5369, XP055620773, ISSN: 0264-410X, DOI: 10.1016/j.vaccine.2010.05.015 *
COPPOCK JOSEPH D. ET AL: "Improved Clearance during Treatment of HPV-Positive Head and Neck Cancer through mTOR Inhibition", NEOPLASIA, vol. 15, no. 6, 1 June 2013 (2013-06-01), US, pages 620 - IN10, XP055873796, ISSN: 1476-5586, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664994/pdf/neo1506_0620.pdf> DOI: 10.1593/neo.13432 *
GARLAND SUZANNE M ET AL: "Safety and immunogenicity of a 9-valent HPV vaccine in females 12-26 years of age who previously received the quadrivalent HPV vaccine", VACCINE, vol. 33, no. 48, 3 August 2015 (2015-08-03), pages 6855 - 6864, XP029332047, ISSN: 0264-410X, DOI: 10.1016/J.VACCINE.2015.08.059 *
See also references of WO2017147475A1 *

Also Published As

Publication number Publication date
IL261340B1 (en) 2023-03-01
BR112018067550A2 (en) 2019-10-01
WO2017147475A1 (en) 2017-08-31
JP2021155448A (en) 2021-10-07
JP7732784B2 (en) 2025-09-02
CO2018009205A2 (en) 2018-09-20
IL261340A (en) 2018-11-29
KR102873848B1 (en) 2025-10-17
JP2023110038A (en) 2023-08-08
IL261340B2 (en) 2023-07-01
EP3419661A1 (en) 2019-01-02
MX2018010338A (en) 2018-11-09
AU2017223970B2 (en) 2022-01-27
SG11201807080UA (en) 2018-09-27
CA3015519A1 (en) 2017-08-31
CN108883168A (en) 2018-11-23
ZA201805679B (en) 2019-11-27
AU2017223970A1 (en) 2018-09-13
JP2019506435A (en) 2019-03-07
MY194694A (en) 2022-12-15
KR20180112043A (en) 2018-10-11
CL2018002438A1 (en) 2019-01-04
HK1256935A1 (en) 2019-10-04

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