EP3452462A4 - SOLID STATE FORMS OF 2- [4- (2- {4- [1- (2-ETHOXYETHYL) -1H-BENZIMIDAZOL-2-YL] -1-PIPERIDINYL} ETHYL) PHENYL] -2-METHYLPROPANOIC ACID AND PREPARATION METHOD THEREOF - Google Patents

SOLID STATE FORMS OF 2- [4- (2- {4- [1- (2-ETHOXYETHYL) -1H-BENZIMIDAZOL-2-YL] -1-PIPERIDINYL} ETHYL) PHENYL] -2-METHYLPROPANOIC ACID AND PREPARATION METHOD THEREOF Download PDF

Info

Publication number
EP3452462A4
EP3452462A4 EP17792622.7A EP17792622A EP3452462A4 EP 3452462 A4 EP3452462 A4 EP 3452462A4 EP 17792622 A EP17792622 A EP 17792622A EP 3452462 A4 EP3452462 A4 EP 3452462A4
Authority
EP
European Patent Office
Prior art keywords
benzimidazol
ethoxyethyl
piperidinyl
phenyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP17792622.7A
Other languages
German (de)
French (fr)
Other versions
EP3452462A1 (en
Inventor
Srinivasan Thirumalai Rajan
Sajja Eswaraiah
Ghojala Venkat Reddy
Sagyam RAJESHWAR REDDY
Singavarapu ADILAKSHMI
Boge RAJESHAM
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSN Laboratories Pvt Ltd
Original Assignee
MSN Laboratories Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MSN Laboratories Pvt Ltd filed Critical MSN Laboratories Pvt Ltd
Publication of EP3452462A1 publication Critical patent/EP3452462A1/en
Publication of EP3452462A4 publication Critical patent/EP3452462A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EP17792622.7A 2016-05-05 2017-05-02 SOLID STATE FORMS OF 2- [4- (2- {4- [1- (2-ETHOXYETHYL) -1H-BENZIMIDAZOL-2-YL] -1-PIPERIDINYL} ETHYL) PHENYL] -2-METHYLPROPANOIC ACID AND PREPARATION METHOD THEREOF Withdrawn EP3452462A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201641015655 2016-05-05
PCT/IN2017/000099 WO2017191651A1 (en) 2016-05-05 2017-05-02 Solid state forms of 2-[4-(2-{4-[1-(2-ethoxyethyl)-1h-benzimidazol-2-yl]-1-piperidinyl}ethyl)phenyl]-2-methylpropanoic acid and process for preparation thereof

Publications (2)

Publication Number Publication Date
EP3452462A1 EP3452462A1 (en) 2019-03-13
EP3452462A4 true EP3452462A4 (en) 2019-10-23

Family

ID=60202837

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17792622.7A Withdrawn EP3452462A4 (en) 2016-05-05 2017-05-02 SOLID STATE FORMS OF 2- [4- (2- {4- [1- (2-ETHOXYETHYL) -1H-BENZIMIDAZOL-2-YL] -1-PIPERIDINYL} ETHYL) PHENYL] -2-METHYLPROPANOIC ACID AND PREPARATION METHOD THEREOF

Country Status (2)

Country Link
EP (1) EP3452462A4 (en)
WO (1) WO2017191651A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021005403A2 (en) * 2018-09-25 2021-06-15 Glenmark Life Sciences Limited processes for preparing bilastine crystalline form 2 and for preparing bilastine p-xylene solvate, and bilastine p-xylene solvate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104447682A (en) * 2013-09-12 2015-03-25 天津市汉康医药生物技术有限公司 Bilastine compound
EP3327012A1 (en) * 2015-07-24 2018-05-30 Disproquima, S.A. Crystalline forms of bilastine and preparation methods thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2124167B1 (en) * 1996-06-04 1999-09-16 Espanola Prod Quimicos NEW DERIVATIVES OF BENZMIDAZOLE WITH ANTIHISTAMINE ACTIVITY.
SI1505066T1 (en) * 2002-04-19 2007-04-30 Faes Farma Sa Polymorph of acid 4-(2-(4-(1-(2-ethoxyethyl)-1h-benzimidazole-2-il)-1-piperidinyl)ethyl)-alpha, alpha-dimethyl-benzeneacetic
KR101123903B1 (en) * 2008-02-12 2012-03-23 주식회사유한양행 Process for preparation of 2-methyl-2'-phenylpropionic acid derivatives and novel intermediate compounds
CZ307500B6 (en) * 2012-08-15 2018-10-24 Zentiva, K.S. A method of the preparation of a 2-methyl-2'-phenylpropionic acid derivative employing novel intermediates

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104447682A (en) * 2013-09-12 2015-03-25 天津市汉康医药生物技术有限公司 Bilastine compound
EP3327012A1 (en) * 2015-07-24 2018-05-30 Disproquima, S.A. Crystalline forms of bilastine and preparation methods thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"SYNTHESIS AND CRYSTALLINE FORMS OF BILASTINE", IP.COM JOURNAL, IP.COM INC., WEST HENRIETTA, NY, US, 23 September 2016 (2016-09-23), XP013172874, ISSN: 1533-0001 *
See also references of WO2017191651A1 *

Also Published As

Publication number Publication date
EP3452462A1 (en) 2019-03-13
WO2017191651A1 (en) 2017-11-09

Similar Documents

Publication Publication Date Title
EP4467143C0 (en) METHOD FOR THE PREPARATION OF 4-(4-(4-(((2-(2,6-DIOXOPIPERIDINE-3-YL)-L-OXOISOINDOLINE-4-YL)OXY)METHYL)BENZYL)PIPERAZINE-L-YL)-3-FLUOROBENZONITRILE
EP3826467A4 (en) PLATFORM FOR THE DEVELOPMENT OF SOIL-BORN PLANT PATHOGENS THAT INHIBIT MICROBIAL CONSORTIA
EP4025214A4 (en) METHOD FOR REDUCING SIDE EFFECTS FROM ADMINISTRATION OF PHOSPHODIESTERASE-4 INHIBITORS
EP3746564A4 (en) NUCLEIC ACID AMPLIFICATION PROCESS
EP3344274A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT OF DISEASE CONDITIONS ASSOCIATED WITH ABNORMAL INFLAMMATORY RESPONSES
EP3353309A4 (en) COMPOSITIONS AND METHODS FOR GENOMIC EDITION
IL256237A (en) Solid forms of (z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidine-5-ylidin)methyl)furan-2-yl)benzoic acid
EP3561059A4 (en) COMPOSITION FOR EDITING BASES FOR AN ANIMAL EMBRYO AND METHOD FOR EDITING BASES
EP3910062A4 (en) MUTANT STRAIN OF PICHIA PASTORIS FOR THE EXPRESSION OF AN EXOGENOUS GENE
EP2831284A4 (en) COMPOSITIONS AND METHODS FOR COLLECTING AND ISOLATING NUCLEIC ACIDS FROM BIOLOGICAL SPECIMENS
DK3644999T3 (en) COMPOSITIONS AND METHODS OF USING 2-(4-CHLOROPHENYL)-N-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-5-YL)METHYL)-2,2-DIFLUORACETAMIDE
EP2578574A4 (en) OPTICALLY ACTIVE DIBENZYLAMINE DERIVATIVE AND PROCESS FOR PREPARING THE SAME
DK2987791T3 (en) 3- (4- (Benzyloxy) phenyl) hex-4-acid acid derivative, suitable for the prevention and treatment of metabolic disorders
EP3529232A4 (en) SULFAMIC ACID DERIVATIVES AND METHODS FOR THEIR PREPARATION
MA46791A (en) COMPOUNDS AND METHODS FOR REDUCING THE EXPRESSION OF ATXN3
EP3411383A4 (en) METHODS FOR EXTRACTING PROTEINS FROM BLOOD MATERIAL
EP3469078A4 (en) METHODS AND COMPOSITIONS FOR AMPLIFICATION OF NUCLEIC ACID
DK3227273T3 (en) COMPOSITIONS INCLUDING 2 - ((1- (2 (4-FLUOROPHENYL) -2-OXOETHYL) PIPERIDIN-4-YL) METHYL) ISOINDOLIN-1-ON, FOR THE TREATMENT OF SKIZOFRENIA
EP3402883A4 (en) COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING
EP3848115A4 (en) LACTIC ACID ABSORBER AND METHOD FOR REMOVAL OF LACTIC ACID
DK2763981T3 (en) PROCEDURE FOR THE PREPARATION OF 1- (4- (4- (3,4-DICHLOR-2-FLUORPHENYLAMINO) -7-METHOXYQUINAZOLIN-6-YLOXY) PIPERIDIN-1-YL) -PROP-2-EN-1-ON HYDROCHLORIDE AND INTERMEDIATES USED THEREOF
EP3368010A4 (en) SOLID GALENIC FORM WITH IMMEDIATE RELEASE OF MEDICINE AND APPARATUS AND METHOD FOR MANUFACTURING THE SAME
EP3859332A4 (en) GLYQUATED HEMOGLOBIN (%) ASSAY METHOD
PL3976589T3 (en) Methods for the preparation of 5-bromo-2-(3-chloropyridin-2-yl)-2H-pyrazole-3-carboxylic acid
EP3486030A4 (en) MACHINING JIG AND METHOD OF MACHINING

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20181205

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20190919

RIC1 Information provided on ipc code assigned before grant

Ipc: C07D 235/14 20060101ALI20190914BHEP

Ipc: C07D 235/08 20060101ALI20190914BHEP

Ipc: C07D 211/62 20060101ALI20190914BHEP

Ipc: C07D 401/04 20060101AFI20190914BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20200702

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20210727