EP3866981A4 - Methods for generating therapeutic delivery platforms - Google Patents

Methods for generating therapeutic delivery platforms Download PDF

Info

Publication number: EP3866981A4
Authority: EP; European Patent Office
Prior art keywords: methods; therapeutic delivery; delivery platforms; generating therapeutic; generating
Prior art date: 2018-10-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19875362.6A

Other languages

German (de)

French (fr)

Other versions

EP3866981A1 (en

Inventor

Mei He

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Kansas

Kansas State University

Original Assignee

University of Kansas

Kansas State University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-10-21

Filing date

2019-10-21

Publication date

2022-09-07

2019-10-21 Application filed by University of Kansas, Kansas State University filed Critical University of Kansas

2021-08-25 Publication of EP3866981A1 publication Critical patent/EP3866981A1/en

2022-09-07 Publication of EP3866981A4 publication Critical patent/EP3866981A4/en

Status Withdrawn legal-status Critical Current

Links

230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/30—Combinations with other devices, not otherwise provided for
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/005—Pretreatment specially adapted for magnetic separation
- B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5076—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving cell organelles, e.g. Golgi complex, endoplasmic reticulum
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4915—Blood using flow cells

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Pathology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
Food Science & Technology (AREA)
Biotechnology (AREA)
Cell Biology (AREA)
Microbiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Tropical Medicine & Parasitology (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

EP19875362.6A 2018-10-21 2019-10-21 Methods for generating therapeutic delivery platforms Withdrawn EP3866981A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201862748470P	2018-10-21	2018-10-21
PCT/US2019/057237 WO2020086471A1 (en)	2018-10-21	2019-10-21	Methods for generating therapeutic delivery platforms

Publications (2)

Publication Number	Publication Date
EP3866981A1 EP3866981A1 (en)	2021-08-25
EP3866981A4 true EP3866981A4 (en)	2022-09-07

Family

ID=70331909

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19875362.6A Withdrawn EP3866981A4 (en)	2018-10-21	2019-10-21	Methods for generating therapeutic delivery platforms

Country Status (9)

Country	Link
EP (1)	EP3866981A4 (en)
JP (1)	JP2022512762A (en)
KR (1)	KR20210088594A (en)
CN (1)	CN113195103A (en)
AU (1)	AU2019368213A1 (en)
BR (1)	BR112021007508A2 (en)
CA (1)	CA3117030A1 (en)
IL (1)	IL282538A (en)
WO (1)	WO2020086471A1 (en)

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US11162143B2 (en)	2018-10-21	2021-11-02	The University Of Kansas	Methods for generating therapeutic delivery platforms
WO2021226589A1 (en) *	2020-05-08	2021-11-11	The University Of Kansas	Immunomagnetic compositions for the ph-specific capture of extracellular vesicles
CN113005021B (en) *	2020-06-17	2023-12-08	山东大学	Microfluidic chip and method for exosome cracking and detection
US20230390773A1 (en) *	2020-10-05	2023-12-07	Clara Biotech, Inc.	Apparatus, system, and method for analyte release
KR20230026261A (en)	2021-08-17	2023-02-24	한국과학기술원	Multi-layered vesicles for induction of immunity, pharmaceutical composition for inducing immunity comprising same, and method of manufacturing multi-layered vesicles for induction of immunity
CN116819058A (en) *	2023-05-18	2023-09-29	国科温州研究院(温州生物材料与工程研究所)	Method for analyzing extracellular vesicular glycans of fluid sample, device and application thereof
WO2025118073A1 (en) *	2023-12-04	2025-06-12	Rocket Science Health Corp.	Magnetic formulations for biomarker sampling and enhanced drug delivery

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2019
- 2019-10-21 BR BR112021007508-9A patent/BR112021007508A2/en not_active Application Discontinuation
- 2019-10-21 CA CA3117030A patent/CA3117030A1/en not_active Abandoned
- 2019-10-21 AU AU2019368213A patent/AU2019368213A1/en not_active Abandoned
- 2019-10-21 WO PCT/US2019/057237 patent/WO2020086471A1/en not_active Ceased
- 2019-10-21 JP JP2021521369A patent/JP2022512762A/en active Pending
- 2019-10-21 EP EP19875362.6A patent/EP3866981A4/en not_active Withdrawn
- 2019-10-21 KR KR1020217015448A patent/KR20210088594A/en not_active Withdrawn
- 2019-10-21 CN CN201980084740.9A patent/CN113195103A/en active Pending
2021
- 2021-04-21 IL IL282538A patent/IL282538A/en unknown

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Also Published As

Publication number	Publication date
CN113195103A (en)	2021-07-30
WO2020086471A1 (en)	2020-04-30
AU2019368213A1 (en)	2021-06-03
JP2022512762A (en)	2022-02-07
EP3866981A1 (en)	2021-08-25
KR20210088594A (en)	2021-07-14
BR112021007508A2 (en)	2021-08-10
IL282538A (en)	2021-06-30
CA3117030A1 (en)	2020-04-30

Legal Events

Date	Code	Title	Description
2020-05-02	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2021-07-23	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2021-07-23	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2021-08-25	17P	Request for examination filed	Effective date: 20210519
2021-08-25	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2022-01-26	DAV	Request for validation of the european patent (deleted)
2022-01-26	DAX	Request for extension of the european patent (deleted)
2022-09-07	A4	Supplementary search report drawn up and despatched	Effective date: 20220810
2022-09-07	RIC1	Information provided on ipc code assigned before grant	Ipc: G01N 33/00 20060101ALI20220804BHEP Ipc: G01N 33/48 20060101ALI20220804BHEP Ipc: B03C 1/02 20060101ALI20220804BHEP Ipc: B03C 1/30 20060101AFI20220804BHEP
2023-07-27	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: EXAMINATION IS IN PROGRESS
2023-08-30	17Q	First examination report despatched	Effective date: 20230726
2024-05-24	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2024-06-26	18D	Application deemed to be withdrawn	Effective date: 20240206

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