EP3905976A4 - SYSTEMS AND METHODS FOR THE TREATMENT OF OBSTRUCTIVE SLEEP APNEA - Google Patents

SYSTEMS AND METHODS FOR THE TREATMENT OF OBSTRUCTIVE SLEEP APNEA Download PDF

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Publication number
EP3905976A4
EP3905976A4 EP19907538.3A EP19907538A EP3905976A4 EP 3905976 A4 EP3905976 A4 EP 3905976A4 EP 19907538 A EP19907538 A EP 19907538A EP 3905976 A4 EP3905976 A4 EP 3905976A4
Authority
EP
European Patent Office
Prior art keywords
systems
treatment
methods
sleep apnea
obstructive sleep
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19907538.3A
Other languages
German (de)
French (fr)
Other versions
EP3905976A1 (en
Inventor
Mark Christopherson
Orhan Soykan
Donald A. Gonzales
Stefan SKORICH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cryosa Inc
Original Assignee
Cryosa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryosa Inc filed Critical Cryosa Inc
Publication of EP3905976A1 publication Critical patent/EP3905976A1/en
Publication of EP3905976A4 publication Critical patent/EP3905976A4/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12Devices for heating or cooling internal body cavities
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/56Devices for preventing snoring
    • A61F5/566Intra-oral devices
    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/0085Devices for generating hot or cold treatment fluids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12Devices for heating or cooling internal body cavities
    • A61F7/123Devices for heating or cooling internal body cavities using a flexible balloon containing the thermal element
    • AHUMAN NECESSITIES
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    • A61B2018/00047Cooling or heating of the probe or tissue immediately surrounding the probe using Peltier effect
    • AHUMAN NECESSITIES
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    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00214Expandable means emitting energy, e.g. by elements carried thereon
    • A61B2018/0022Balloons
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    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00642Sensing and controlling the application of energy with feedback, i.e. closed loop control
    • A61B2018/00648Sensing and controlling the application of energy with feedback, i.e. closed loop control using more than one sensed parameter
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61B2018/00744Fluid flow
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    • A61B2018/0262Characteristics of handpieces or probes using a circulating cryogenic fluid
    • AHUMAN NECESSITIES
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0002Head or parts thereof
    • A61F2007/0009Throat or neck
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    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001Body part
    • A61F2007/0002Head or parts thereof
    • A61F2007/0017Mouth
    • AHUMAN NECESSITIES
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    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0054Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
    • A61F2007/0056Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/0063Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit for cooling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/0069Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit with return means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0075Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0091Heating or cooling appliances for medical or therapeutic treatment of the human body inflatable
    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12Devices for heating or cooling internal body cavities
    • A61F2007/126Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Surgical Instruments (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
EP19907538.3A 2018-12-31 2019-12-31 SYSTEMS AND METHODS FOR THE TREATMENT OF OBSTRUCTIVE SLEEP APNEA Pending EP3905976A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862787125P 2018-12-31 2018-12-31
US201962890884P 2019-08-23 2019-08-23
PCT/US2019/069113 WO2020142519A1 (en) 2018-12-31 2019-12-31 Systems and methods for treatment of obstructive sleep apnea

Publications (2)

Publication Number Publication Date
EP3905976A1 EP3905976A1 (en) 2021-11-10
EP3905976A4 true EP3905976A4 (en) 2022-09-21

Family

ID=71407221

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19907538.3A Pending EP3905976A4 (en) 2018-12-31 2019-12-31 SYSTEMS AND METHODS FOR THE TREATMENT OF OBSTRUCTIVE SLEEP APNEA

Country Status (6)

Country Link
US (1) US12558257B2 (en)
EP (1) EP3905976A4 (en)
JP (1) JP2022520156A (en)
AU (1) AU2019419502A1 (en)
CA (1) CA3125291A1 (en)
WO (1) WO2020142519A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012103315A2 (en) 2011-01-27 2012-08-02 Osa Holdings, Inc. Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
US11304746B2 (en) 2011-06-14 2022-04-19 Aerin Medical Inc. Method of treating airway tissue to reduce mucus secretion
US20240050143A1 (en) 2011-06-14 2024-02-15 Aerin Medical Inc. Methods and devices to treat nasal airways
SG10201607576PA (en) 2011-06-14 2016-11-29 Aerin Medical Inc Devices for treating nasal airways
WO2017152061A1 (en) 2016-03-04 2017-09-08 Aerin Medical, Inc. Eustachian tube modification
US11806071B2 (en) 2016-12-22 2023-11-07 Aerin Medical Inc. Soft palate treatment
WO2020142519A1 (en) 2018-12-31 2020-07-09 Cryosa, Inc. Systems and methods for treatment of obstructive sleep apnea
CN115135263A (en) * 2020-02-19 2022-09-30 科瑞奥萨公司 System and method for treating obstructive sleep apnea
US11806272B2 (en) 2020-03-04 2023-11-07 Randall Ow Devices and methods for treating obstructive breathing disorders
WO2022187447A2 (en) * 2021-03-03 2022-09-09 Randall Ow Devices and methods for treating obstructive breathing disorders
US20220151689A1 (en) * 2020-11-16 2022-05-19 Aerin Medical Inc. Soft palate treatment
US12357817B2 (en) 2021-04-06 2025-07-15 Aerin Medical Inc. Nasal neuromodulation devices and methods
JP2025502801A (en) 2021-12-30 2025-01-28 クライオサ, インク. Systems and methods for treating obstructive sleep apnea - Patents.com
US12558549B2 (en) 2022-10-28 2026-02-24 Medtronic, Inc. Lead based measurements for tongue movement determination

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6378525B1 (en) * 1998-01-29 2002-04-30 American Medical Systems, Inc. Combined cryotherapy and hyperthermia method for the treatment of airway obstruction or prostrate enlargement
US20090123886A1 (en) * 2007-11-13 2009-05-14 Apnicure, Inc. Methods and systems for saliva management with an oral device
US20120197361A1 (en) * 2011-01-27 2012-08-02 Gonzales Donald A Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
US20160354234A1 (en) * 2012-12-14 2016-12-08 Zoll Circulation, Inc. System And Method For Management Of Body Temperature
US20170246032A1 (en) * 2014-10-01 2017-08-31 Cryosa, Llc Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
WO2017223417A1 (en) * 2016-06-24 2017-12-28 Board Of Regents, The University Of Texas System Dual temperature, dual reservoir contrast programmable therapy devices and methods of using the same

Family Cites Families (193)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5231674B1 (en) 1969-03-29 1977-08-16
US3712306A (en) * 1971-11-09 1973-01-23 Brymill Corp Cryogenic application chamber and method
US3889680A (en) 1974-02-07 1975-06-17 Armao T A Cryoadhesion preventing cryosurgical instruments
US5250430A (en) 1987-06-29 1993-10-05 Massachusetts Institute Of Technology Polyhydroxyalkanoate polymerase
US5245023A (en) 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
JPH01223961A (en) 1988-03-02 1989-09-07 Kineshio:Kk Method for improvement of muscle subcutaneous tissue and subcutaneous tissue activating device
US6770071B2 (en) 1995-06-07 2004-08-03 Arthrocare Corporation Bladed electrosurgical probe
US6832996B2 (en) 1995-06-07 2004-12-21 Arthrocare Corporation Electrosurgical systems and methods for treating tissue
US5730719A (en) 1994-05-09 1998-03-24 Somnus Medical Technologies, Inc. Method and apparatus for cosmetically remodeling a body structure
US5800379A (en) * 1996-02-23 1998-09-01 Sommus Medical Technologies, Inc. Method for ablating interior sections of the tongue
US20010051783A1 (en) 1996-02-23 2001-12-13 Stuart D. Edwards Method and apparatus for treatment of air way obstructions
US6126657A (en) 1996-02-23 2000-10-03 Somnus Medical Technologies, Inc. Apparatus for treatment of air way obstructions
US5743904A (en) 1996-05-06 1998-04-28 Somnus Medical Technologies, Inc. Precision placement of ablation apparatus
BE1010730A7 (en) 1996-11-04 1998-12-01 Pira Luc Louis Marie Francis Cryoprobe based on peltier module.
GB9624456D0 (en) 1996-11-25 1997-01-15 Isis Innovation Assay method
US6041787A (en) 1997-03-17 2000-03-28 Rubinsky; Boris Use of cryoprotective agent compounds during cryosurgery
US6032675A (en) 1997-03-17 2000-03-07 Rubinsky; Boris Freezing method for controlled removal of fatty tissue by liposuction
US6610764B1 (en) 1997-05-12 2003-08-26 Metabolix, Inc. Polyhydroxyalkanoate compositions having controlled degradation rates
AU7486798A (en) 1997-05-12 1998-12-08 Metabolix, Inc. Polyhydroxyalkanoates for (in vivo) applications
US6867248B1 (en) 1997-05-12 2005-03-15 Metabolix, Inc. Polyhydroxyalkanoate compositions having controlled degradation rates
WO1999003411A1 (en) 1997-07-17 1999-01-28 Somnus Medical Technologies, Inc. Method and apparatus for treatment of air way obstructions
US6828357B1 (en) 1997-07-31 2004-12-07 Metabolix, Inc. Polyhydroxyalkanoate compositions having controlled degradation rates
WO1999014313A2 (en) 1997-09-19 1999-03-25 Metabolix, Inc. Biological systems for manufacture of polyhydroxylalkanoate polymers containing 4-hydroxyacids
US6045549A (en) 1997-09-30 2000-04-04 Somnus Medical Technologies, Inc. Tissue ablation apparatus and device for use therein and method
WO2000011188A1 (en) 1998-08-18 2000-03-02 Metabolix, Inc. Transgenic microbial polyhydroxyalkanoate producers
US6514515B1 (en) 1999-03-04 2003-02-04 Tepha, Inc. Bioabsorbable, biocompatible polymers for tissue engineering
EP2305324B1 (en) 1999-03-25 2014-09-17 Metabolix, Inc. Medical devices and applications of polyhydroxyalkanoate polymers
US6699400B1 (en) 1999-06-04 2004-03-02 Arne W. Ballantine Etch process and apparatus therefor
EP1212046A2 (en) 1999-08-30 2002-06-12 Tepha, Inc. Flushable disposable polymeric products
US7025980B1 (en) 1999-09-14 2006-04-11 Tepha, Inc. Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation
US6408851B1 (en) 1999-10-01 2002-06-25 Manuel L. Karell Method and device for holding a tongue in a forward position
US6447443B1 (en) 2001-01-13 2002-09-10 Medtronic, Inc. Method for organ positioning and stabilization
US6840955B2 (en) 2000-01-27 2005-01-11 Robert J. Ein Therapeutic apparatus
DE60120415T2 (en) 2000-07-21 2007-01-04 Metabolix, Inc., Cambridge PREPARATION OF POLYHYDROXYALKANOATES FROM POLYOLES
US7338441B2 (en) 2001-09-06 2008-03-04 Houser Russell A Superelastic/shape memory tissue stabilizers and surgical instruments
US6652518B2 (en) 2001-09-28 2003-11-25 Ethicon, Inc. Transmural ablation tool and method
US20030220374A1 (en) 2002-01-14 2003-11-27 Pharmacia Corporation Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
US8840608B2 (en) 2002-03-15 2014-09-23 The General Hospital Corporation Methods and devices for selective disruption of fatty tissue by controlled cooling
DE60319207T2 (en) 2002-03-15 2009-02-12 The General Hospital Corp., Boston DEVICES FOR THE SELECTIVE DESTRUCTION OF FAT FABRIC BY CONTROLLED COOLING
AU2004238229B2 (en) 2003-05-08 2007-07-12 Tepha, Inc. Polyhydroxyalkanoate medical textiles and fibers
US7149574B2 (en) 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
US20050043682A1 (en) 2003-08-22 2005-02-24 Cannuflow Incorporated Flexible inflow/outflow cannula and flexible instrument port
US7458932B2 (en) 2003-12-09 2008-12-02 Sun William Y Tongue stabilizer for laryngoscope blade
US20050133026A1 (en) 2003-12-23 2005-06-23 Katie Seleznev Device for the treatment of snoring and obstructive sleep apnea
BRPI0507224A (en) 2004-02-26 2007-06-19 Iras Sanders method and device for the treatment of obstructive sleep apnea and snoring
US8074655B2 (en) 2004-02-26 2011-12-13 Linguaflex, Inc. Methods and devices for treating sleep apnea and snoring
US7842029B2 (en) 2004-05-07 2010-11-30 Aesthera Apparatus and method having a cooling material and reduced pressure to treat biological external tissue
US8096303B2 (en) 2005-02-08 2012-01-17 Koninklijke Philips Electronics N.V Airway implants and methods and devices for insertion and retrieval
US9408742B2 (en) 2005-02-08 2016-08-09 Koninklijke Philips N.V. Glossopexy adjustment system and method
US7337781B2 (en) 2005-04-15 2008-03-04 Restore Medical, Inc. Implant for tongue
US7850683B2 (en) 2005-05-20 2010-12-14 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US7713266B2 (en) 2005-05-20 2010-05-11 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US8186355B2 (en) 2005-11-09 2012-05-29 Koninklijke Philips Electronics N.V. Glossoplasty using tissue anchor glossopexy with volumetric tongue reduction
US20070154538A1 (en) 2005-12-29 2007-07-05 Ceramoptec Gmbh Removal of fat cells by PDT
US20070163603A1 (en) 2006-01-18 2007-07-19 Sikora Val J Tongue retention device and method of use
US7854754B2 (en) 2006-02-22 2010-12-21 Zeltiq Aesthetics, Inc. Cooling device for removing heat from subcutaneous lipid-rich cells
CA2585214C (en) 2006-04-28 2011-05-31 Juniper Medical, Inc. Cryoprotectant for use with a treatment device for improved cooling of subcutaneous lipid-rich cells
US20070270925A1 (en) 2006-05-17 2007-11-22 Juniper Medical, Inc. Method and apparatus for non-invasively removing heat from subcutaneous lipid-rich cells including a coolant having a phase transition temperature
WO2007146362A2 (en) 2006-06-13 2007-12-21 Aspire Medical, Inc. Glossopexy tension system and method
WO2008016730A2 (en) 2006-08-02 2008-02-07 Targeted Molecular Diagnostics, Llc Compositions and methods for reducing cellular fat
US9132031B2 (en) 2006-09-26 2015-09-15 Zeltiq Aesthetics, Inc. Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
US8192474B2 (en) 2006-09-26 2012-06-05 Zeltiq Aesthetics, Inc. Tissue treatment methods
US20080077201A1 (en) 2006-09-26 2008-03-27 Juniper Medical, Inc. Cooling devices with flexible sensors
US20080083461A1 (en) 2006-10-05 2008-04-10 Viken James P Fluid exchange apparatus with locking flow alignment device
WO2008045877A2 (en) 2006-10-10 2008-04-17 St. Jude Medical, Atrial Fibrillation Division, Inc. Electrode tip and ablation system
WO2008055243A2 (en) 2006-10-31 2008-05-08 Zeltiq Aesthetics, Inc. Method and apparatus for cooling subcutaneous lipid-rich cells or tissue
US8079263B2 (en) 2006-11-10 2011-12-20 Penrith Corporation Transducer array imaging system
US7758577B2 (en) 2006-12-05 2010-07-20 Ethicon Endo-Surgery, Inc. Monopolar resection device and method of use
US9254162B2 (en) 2006-12-21 2016-02-09 Myoscience, Inc. Dermal and transdermal cryogenic microprobe systems
US8409185B2 (en) 2007-02-16 2013-04-02 Myoscience, Inc. Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling
US20090107001A1 (en) 2007-03-19 2009-04-30 Hemcon Medical Technologies, Inc. Apparatus and methods for making, storing, and administering freeze-dried materials such as freeze-dried plasma
USD568258S1 (en) 2007-04-06 2008-05-06 Zeltiq Aesthetics, Inc. Control unit
US20080287839A1 (en) 2007-05-18 2008-11-20 Juniper Medical, Inc. Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator
US20090018627A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Secure systems for removing heat from lipid-rich regions
WO2009011708A1 (en) 2007-07-13 2009-01-22 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
US20090018624A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Limiting use of disposable system patient protection devices
US8523927B2 (en) 2007-07-13 2013-09-03 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
US20090018626A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. User interfaces for a system that removes heat from lipid-rich regions
US20090018625A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Managing system temperature to remove heat from lipid-rich regions
EP3488833B1 (en) 2007-08-21 2025-10-22 Zeltiq Aesthetics, Inc. Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue
US8287579B2 (en) 2007-09-17 2012-10-16 Thermage, Inc. Method of using cryogenic compositions for cooling heated skin
US8298216B2 (en) 2007-11-14 2012-10-30 Myoscience, Inc. Pain management using cryogenic remodeling
US20090192504A1 (en) 2008-01-29 2009-07-30 Csa Medical, Inc. Cryosurgery system having unintegrated delivery and visualization apparatus
CA2739072A1 (en) 2008-04-01 2009-12-03 The General Hospital Corporation Method and apparatus for cooling biological tissue
WO2009140495A2 (en) 2008-05-14 2009-11-19 Physcient, Inc. Methods and devices to decrease tissue trauma during surgery
US9089316B2 (en) 2009-11-02 2015-07-28 Endocare, Inc. Cryogenic medical system
US20100057065A1 (en) 2008-09-04 2010-03-04 Reset Medical, Inc. Method for cryospray ablation
DE102008048686B4 (en) 2008-09-24 2015-01-08 Siemens Aktiengesellschaft Driving system and driving method
US8275442B2 (en) 2008-09-25 2012-09-25 Zeltiq Aesthetics, Inc. Treatment planning systems and methods for body contouring applications
US8603073B2 (en) 2008-12-17 2013-12-10 Zeltiq Aesthetics, Inc. Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells
CA2975717C (en) 2009-04-30 2020-04-28 Zeltiq Aesthetics, Inc. Device, system and method of removing heat from subcutaneous lipid-rich cells
WO2010135602A1 (en) 2009-05-20 2010-11-25 Osseon Therapeutics, Inc. Steerable curvable ablation catheter for vertebroplasty
WO2011068952A1 (en) 2009-12-02 2011-06-09 Entrigue Surgical, Inc. Devices for tongue stabilization
US20110300079A1 (en) 2010-01-21 2011-12-08 Zeltiq Aesthetics, Inc. Compositions for use with a system for improved cooling of subcutaneous lipid-rich tissue
US9844461B2 (en) 2010-01-25 2017-12-19 Zeltiq Aesthetics, Inc. Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants
WO2011100692A1 (en) 2010-02-15 2011-08-18 The General Hospital Corporation Methods and devices for selective disruption of visceral fat by controlled cooling
US8676338B2 (en) 2010-07-20 2014-03-18 Zeltiq Aesthetics, Inc. Combined modality treatment systems, methods and apparatus for body contouring applications
CN103118613A (en) 2010-08-26 2013-05-22 克莱米迪克斯有限责任公司 Cryoablation balloon catheter and related method
SG191161A1 (en) 2010-12-13 2013-08-30 Myoscience Inc Method for reducing hyperdynamic facial wrinkles
US10441459B2 (en) 2010-12-29 2019-10-15 Ethicon Endo-Surgery, Inc. Methods and devices for activating brown adipose tissue with cooling
US10722395B2 (en) 2011-01-25 2020-07-28 Zeltiq Aesthetics, Inc. Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells
BR112013019091B1 (en) * 2011-02-01 2022-02-01 Channel Medsystems, Inc fabric treatment system
US20110155143A1 (en) 2011-03-11 2011-06-30 Shantha Totada R Snoring and obstructive sleep apnea prevention and treatment device
US10722282B2 (en) 2011-06-14 2020-07-28 Aerin Medical, Inc. Methods and devices to treat nasal airways
SG10201607576PA (en) 2011-06-14 2016-11-29 Aerin Medical Inc Devices for treating nasal airways
US11304746B2 (en) 2011-06-14 2022-04-19 Aerin Medical Inc. Method of treating airway tissue to reduce mucus secretion
US20150039045A1 (en) 2011-08-11 2015-02-05 Inspire Medical Systems, Inc. Method and system for applying stimulation in treating sleep disordered breathing
US8934992B2 (en) 2011-09-01 2015-01-13 Inspire Medical Systems, Inc. Nerve cuff
EP2773276B1 (en) * 2011-11-05 2018-04-04 Medtronic Ardian Luxembourg S.à.r.l. Systems for crynogenic renal neuromodulation
EP2802279B1 (en) 2012-01-13 2017-08-16 Myoscience, Inc. Cryogenic needle with freeze zone regulation
US9717546B2 (en) 2012-05-21 2017-08-01 Jhpiego Corporation Cryotherapy device and method for the treatment of cervical precancerous lesions
ES2606243T3 (en) 2012-07-19 2017-03-23 High Technology Products, Sl Head for cold therapy device
US9724631B2 (en) 2012-10-10 2017-08-08 Ingersoll-Rand Company Filter element adaptor for compressed air filter
US8768468B2 (en) 2012-10-30 2014-07-01 Mitosis, Inc. Device for neuro-physiologic stimulation
ITMI20130234A1 (en) 2013-02-20 2014-08-21 Messersi Packaging Srl ROTARY WRAPPING MACHINE FOR PACKAGING OBJECTS.
US9545523B2 (en) 2013-03-14 2017-01-17 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue
US9844460B2 (en) * 2013-03-14 2017-12-19 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
US9033966B2 (en) 2013-03-15 2015-05-19 Warsaw Orthopedic, Inc. Nerve and soft tissue ablation device
WO2014146126A1 (en) 2013-03-15 2014-09-18 Myoscience, Inc. Cryogenic blunt dissection methods and devices
US9295512B2 (en) 2013-03-15 2016-03-29 Myoscience, Inc. Methods and devices for pain management
US9610112B2 (en) 2013-03-15 2017-04-04 Myoscience, Inc. Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis
WO2015021348A2 (en) 2013-08-09 2015-02-12 Inspire Medical Systems, Inc. Patient control for implantable medical device
ES2793936T3 (en) 2013-11-26 2020-11-17 Corfigo Inc Wide-area, dual-chamber superimposed action / neutralization tissue ablation device
GB201323171D0 (en) 2013-12-31 2014-02-12 Creo Medical Ltd Electrosurgical apparatus and device
WO2015117001A1 (en) 2014-01-31 2015-08-06 Zeltiq Aesthetics, Inc. Compositions, treatment systems and methods for improved cooling of lipid-rich tissue
EP3099262B1 (en) 2014-01-31 2022-02-23 The General Hospital Corporation Cooling device to disrupt function sebaceous glands
CN106456231B (en) 2014-02-12 2020-12-25 通用医疗公司 Method and apparatus for affecting tissue pigmentation
US10568759B2 (en) 2014-08-19 2020-02-25 Zeltiq Aesthetics, Inc. Treatment systems, small volume applicators, and methods for treating submental tissue
US10646666B2 (en) 2014-08-27 2020-05-12 Tva Medical, Inc. Cryolipolysis devices and methods therefor
US11504322B2 (en) 2014-08-28 2022-11-22 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
BR112017003143B1 (en) 2014-08-28 2023-12-05 The General Hospital Corporation INJECTABLE SUSPENSIONS, METHODS FOR MANUFACTURING THEM AND THEIR USES
WO2016090175A1 (en) 2014-12-03 2016-06-09 Metavention, Inc. Systems and methods for modulating nerves or other tissue
US10470813B2 (en) 2015-03-12 2019-11-12 Pacira Cryotech, Inc. Methods and systems for preventing neuroma formations
WO2017053324A1 (en) 2015-09-21 2017-03-30 Zeltiq Aesthetics, Inc. Transcutaneous treatment systems and cooling devices
WO2017070112A1 (en) 2015-10-19 2017-04-27 Zeltiq Aesthetics, Inc. Vascular treatment systems, cooling devices, and methods for cooling vascular structures
US11253717B2 (en) 2015-10-29 2022-02-22 Btl Healthcare Technologies A.S. Aesthetic method of biological structure treatment by magnetic field
EP3399950A1 (en) 2016-01-07 2018-11-14 Zeltiq Aesthetics, Inc. Temperature-dependent adhesion between applicator and skin during cooling of tissue
US11517365B1 (en) 2016-02-04 2022-12-06 Meital Mazor Devices and methods for treatment of dermatological conditions
US10765552B2 (en) 2016-02-18 2020-09-08 Zeltiq Aesthetics, Inc. Cooling cup applicators with contoured heads and liner assemblies
US11298261B2 (en) 2016-04-04 2022-04-12 Chemomouthpiece, Llc Mouth piece for cooling of oral tissue of a user during therapeutic treatment
WO2017184753A1 (en) 2016-04-19 2017-10-26 Inspire Medical Systems, Inc. Accelerometer-based sensing for sleep disordered breathing (sdb) care
US11382790B2 (en) 2016-05-10 2022-07-12 Zeltiq Aesthetics, Inc. Skin freezing systems for treating acne and skin conditions
US10555831B2 (en) 2016-05-10 2020-02-11 Zeltiq Aesthetics, Inc. Hydrogel substances and methods of cryotherapy
AU2017264512A1 (en) 2016-05-10 2018-11-22 Zeltiq Aesthetics, Inc. Skin freezing systems for treating acne and skin conditions
US10682297B2 (en) 2016-05-10 2020-06-16 Zeltiq Aesthetics, Inc. Liposomes, emulsions, and methods for cryotherapy
US20170326346A1 (en) 2016-05-10 2017-11-16 Zeltiq Aesthetics, Inc. Permeation enhancers and methods of cryotherapy
JP2019531168A (en) 2016-08-30 2019-10-31 ザ ジェネラル ホスピタル コーポレイション Cryotherapy and cryoablation systems and methods for cell tissue treatment
US11324673B2 (en) 2016-11-18 2022-05-10 Miraki Innovation Think Tank Llc Cosmetic appearance of skin
US11806071B2 (en) 2016-12-22 2023-11-07 Aerin Medical Inc. Soft palate treatment
MA47095A (en) 2016-12-22 2019-10-30 Aerin Medical Inc PALAIS MOU TREATMENT
EP3342379B1 (en) 2016-12-27 2019-10-23 Suvaddhana Sarin Loap Non-shivering cryothermogenesis method for reducing adipose tissues
JP7218292B2 (en) 2017-01-10 2023-02-06 インスパイア・メディカル・システムズ・インコーポレイテッド Power Elements of Implantable Medical Devices
CN110430832B (en) 2017-01-17 2023-07-04 科菲戈公司 Apparatus for ablation of tissue surfaces and related systems and methods
US12226139B2 (en) 2017-01-19 2025-02-18 The General Hospital Corporation Systems and methods for thermal treatment of tissue
BR112019018191A2 (en) 2017-03-01 2020-06-23 Miraki Innovation Think Tank Llc CRIOTHERAPIES
AU2018250270A1 (en) 2017-04-05 2019-10-31 Miraki Innovation Think Tank Llc Point of delivery cold slurry generation
BR112019020969A8 (en) 2017-04-05 2022-11-16 Miraki Innovation Think Tank Llc COLD FLUID PASTE CONTAINMENT
US11076879B2 (en) 2017-04-26 2021-08-03 Zeltiq Aesthetics, Inc. Shallow surface cryotherapy applicators and related technology
AU2018204843B2 (en) 2017-07-05 2023-07-27 Medtronic Ardian Luxembourg S.A.R.L. Methods for treating anxiety disorders in patients via renal neuromodulation
EP3664889B1 (en) 2017-08-11 2024-02-21 Inspire Medical Systems, Inc. Cuff electrode
US11842257B2 (en) 2017-12-27 2023-12-12 Marlabs Incorporated System and method for predicting and scoring a data model
US11437150B2 (en) 2018-05-31 2022-09-06 Inspire Medical Systems, Inc. System and method for secured sharing of medical data generated by a patient medical device
CN108836619A (en) 2018-07-17 2018-11-20 北京麦邦光电仪器有限公司 Target temperature treatment probe, treatment pincers and target temperature therapeutic device
CN109009406B (en) 2018-07-23 2020-02-21 山前(珠海)医疗科技有限公司 Cryoablation device and cryoablation method
JP2021532873A (en) 2018-07-31 2021-12-02 ゼルティック エステティックス インコーポレイテッド Methods, devices, and systems to improve skin properties
US20200069458A1 (en) 2018-08-31 2020-03-05 Zeltiq Aesthetics, Inc. Compositions, treatment systems, and methods for fractionally freezing tissue
CA3113416A1 (en) 2018-09-18 2020-03-26 Meital Mazor Thermal devices and methods of visceral fat reduction
KR20210073541A (en) 2018-10-04 2021-06-18 미라키 이노베이션 씽크 탱크 엘엘씨 How to treat the subcutaneous fat layer
AU2019359364A1 (en) 2018-10-12 2021-05-20 Miraki Innovation Think Tank Llc Cold solution for fat reduction
WO2020142519A1 (en) 2018-12-31 2020-07-09 Cryosa, Inc. Systems and methods for treatment of obstructive sleep apnea
WO2020168124A1 (en) 2019-02-13 2020-08-20 The General Hospital Corporation Localized cooling to induce browning of adipose tissue
JP2022528200A (en) 2019-04-10 2022-06-08 アークティクス エルエルシー Vacuum-driven cooling and freezing based on water evaporation
EP3976169A1 (en) 2019-05-24 2022-04-06 Inspire Medical Systems, Inc. Systems and methods for treating incontinence
EP3747467A3 (en) 2019-06-03 2021-03-03 Nanobacterie A cryosystem comprising nanoparticles for treating a body part of an individual by cryotherapy
CA3156012A1 (en) 2019-09-26 2021-04-01 Miraki Innovation Think Tank Llc Miniaturized intra-body controllable medical device
US20230000669A1 (en) 2019-11-20 2023-01-05 B2M Medical, Inc. Systems and methods for treatment of visceral fat
US20230054472A1 (en) 2019-12-23 2023-02-23 Miraki Innovation Think Tank Llc Sample preparation and microbial analysis
BR112022012482A2 (en) 2019-12-24 2022-11-22 Miraki Innovation Think Tank Llc COMPOSITION, AND, METHODS FOR TREATMENT OF SUBCUTANEOUS ADIPOSE TISSUE, TO CREATE A TREATMENT PLAN FOR A SUBJECT AND TO GENERATE A COMPOSITION
US20230046673A1 (en) 2019-12-26 2023-02-16 Miraki Innovation Think Tank Llc Treatment of obstructive sleep apnea
WO2021138252A1 (en) 2019-12-31 2021-07-08 Miraki Innovative Think Tank Llc Cold solution for inducing therapeutic hypothermia
JP7789004B2 (en) 2020-02-14 2025-12-19 インスパイア・メディカル・システムズ・インコーポレイテッド Stimulating electrode assembly, system and method for treating sleep disordered breathing
CN116096317A (en) 2020-08-14 2023-05-09 斯尔替克美学股份有限公司 Multi-applicator systems and methods for body contouring
WO2022169699A1 (en) 2021-02-04 2022-08-11 Inspire Medical Systems, Inc. Implantable medical devices at least partially formed from a thermoset material
USD971950S1 (en) 2021-02-10 2022-12-06 Inspire Medical Systems, Inc. Display screen or portion thereof with a graphical user interface
USD971936S1 (en) 2021-02-10 2022-12-06 Inspire Medical Systems, Inc. Display screen or portion thereof with a graphical user interface
USD967164S1 (en) 2021-02-10 2022-10-18 Inspire Medical Systems, Inc. Display screen or portion thereof with a graphical user interface
USD971937S1 (en) 2021-02-10 2022-12-06 Inspire Medical Systems, Inc. Display screen or portion thereof with a graphical user interface
USD971935S1 (en) 2021-02-10 2022-12-06 Inspire Medical Systems, Inc. Display screen or portion thereof with a graphical user interface
EP4082460A1 (en) 2021-04-28 2022-11-02 High Technology Products, S.L.U. Methods and systems for determining freezing of skin during cooling
WO2023278891A1 (en) 2021-07-02 2023-01-05 Miraki Innovation Think Tank Llc Compositions, systems and methods for treating suprapubic fat
EP4415725A1 (en) 2021-10-14 2024-08-21 The General Hospital Corporation Compositions and methods for treatment of obstructive sleep apnea
JP2025502801A (en) 2021-12-30 2025-01-28 クライオサ, インク. Systems and methods for treating obstructive sleep apnea - Patents.com
WO2025090362A1 (en) 2023-10-27 2025-05-01 Cryosa, Inc. Methods and systems for inducing apoptosis of adipose cells

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6378525B1 (en) * 1998-01-29 2002-04-30 American Medical Systems, Inc. Combined cryotherapy and hyperthermia method for the treatment of airway obstruction or prostrate enlargement
US20090123886A1 (en) * 2007-11-13 2009-05-14 Apnicure, Inc. Methods and systems for saliva management with an oral device
US20120197361A1 (en) * 2011-01-27 2012-08-02 Gonzales Donald A Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
US20160354234A1 (en) * 2012-12-14 2016-12-08 Zoll Circulation, Inc. System And Method For Management Of Body Temperature
US20170246032A1 (en) * 2014-10-01 2017-08-31 Cryosa, Llc Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
WO2017223417A1 (en) * 2016-06-24 2017-12-28 Board Of Regents, The University Of Texas System Dual temperature, dual reservoir contrast programmable therapy devices and methods of using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2020142519A1 *

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