EP4288062A4 - Fospropofol-verfahren und -zusammensetzungen - Google Patents

Fospropofol-verfahren und -zusammensetzungen

Info

Publication number
EP4288062A4
EP4288062A4 EP21925083.4A EP21925083A EP4288062A4 EP 4288062 A4 EP4288062 A4 EP 4288062A4 EP 21925083 A EP21925083 A EP 21925083A EP 4288062 A4 EP4288062 A4 EP 4288062A4
Authority
EP
European Patent Office
Prior art keywords
fospropofol
compositions
methods
fospropofol methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21925083.4A
Other languages
English (en)
French (fr)
Other versions
EP4288062A1 (de
Inventor
Steven L. Krill
Feng-Jing Chen
Randall B. Murphy
Michael A. Rogawski
Allen HELLER
Edward Brendan MAGRAB
Samuel ANDREW
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epalex Corp
Original Assignee
Epalex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/168,365 external-priority patent/US11547714B2/en
Priority claimed from US17/217,656 external-priority patent/US11207334B1/en
Priority claimed from US17/387,059 external-priority patent/US11478490B1/en
Priority claimed from US17/466,016 external-priority patent/US11439653B1/en
Priority claimed from US17/465,966 external-priority patent/US20220313711A1/en
Application filed by Epalex Corp filed Critical Epalex Corp
Publication of EP4288062A1 publication Critical patent/EP4288062A1/de
Publication of EP4288062A4 publication Critical patent/EP4288062A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP21925083.4A 2021-02-05 2021-12-27 Fospropofol-verfahren und -zusammensetzungen Pending EP4288062A4 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US17/168,365 US11547714B2 (en) 2020-02-05 2021-02-05 Fospropofol salts, methods and compositions
US17/217,656 US11207334B1 (en) 2021-03-30 2021-03-30 Fospropofol formulations
US17/387,059 US11478490B1 (en) 2021-03-30 2021-07-28 Fospropofol formulations
US17/466,016 US11439653B1 (en) 2021-03-30 2021-09-03 Fospropofol formulations
US17/465,966 US20220313711A1 (en) 2021-03-30 2021-09-03 Fospropofol formulations
PCT/US2021/065225 WO2022169520A1 (en) 2021-02-05 2021-12-27 Fospropofol methods and compositions

Publications (2)

Publication Number Publication Date
EP4288062A1 EP4288062A1 (de) 2023-12-13
EP4288062A4 true EP4288062A4 (de) 2025-02-19

Family

ID=82741701

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21925083.4A Pending EP4288062A4 (de) 2021-02-05 2021-12-27 Fospropofol-verfahren und -zusammensetzungen

Country Status (6)

Country Link
EP (1) EP4288062A4 (de)
JP (1) JP2024508686A (de)
AU (1) AU2021426502A1 (de)
CA (1) CA3207194A1 (de)
IL (1) IL304824A (de)
WO (1) WO2022169520A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116570718B (zh) * 2023-04-26 2025-09-30 四川大学华西医院 一种包含局麻药和磷丙泊酚二钠的药物组合物、其制备方法和用途以及一种联合用药物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200289404A1 (en) * 2016-05-27 2020-09-17 The Johns Hopkins University Buccal, sublingual and intranasal delivery of fospropofol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2597956C (en) * 2005-02-17 2013-07-09 Velcera Pharmaceuticals Transmucosal administration of drug compositions for treating and preventing disorders in animals
EP1951248A4 (de) * 2005-11-14 2011-05-25 Peter D Winch Neue farbige lösungen von injizierbaren arzneimitteln und ihren pharmazeutisch annehmbaren salzen
DK2661280T3 (en) * 2011-01-04 2019-03-04 Novaliq Gmbh O / V EMULSIONS INCLUDING SEMIFLUORINATED ALKANES

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200289404A1 (en) * 2016-05-27 2020-09-17 The Johns Hopkins University Buccal, sublingual and intranasal delivery of fospropofol

Also Published As

Publication number Publication date
IL304824A (en) 2023-09-01
JP2024508686A (ja) 2024-02-28
WO2022169520A1 (en) 2022-08-11
EP4288062A1 (de) 2023-12-13
CA3207194A1 (en) 2022-08-11
AU2021426502A1 (en) 2023-08-17

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Legal Events

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Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20250121

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 9/24 20060101ALI20250115BHEP

Ipc: A61K 9/20 20060101ALI20250115BHEP

Ipc: A61K 9/00 20060101ALI20250115BHEP

Ipc: A61K 31/661 20060101AFI20250115BHEP