ES2051919T3 - Preparado para via oral de un compuesto de un acido inestable. - Google Patents

Preparado para via oral de un compuesto de un acido inestable.

Info

Publication number
ES2051919T3
ES2051919T3 ES89108492T ES89108492T ES2051919T3 ES 2051919 T3 ES2051919 T3 ES 2051919T3 ES 89108492 T ES89108492 T ES 89108492T ES 89108492 T ES89108492 T ES 89108492T ES 2051919 T3 ES2051919 T3 ES 2051919T3
Authority
ES
Spain
Prior art keywords
unstable acid
composite
prepared
oral use
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89108492T
Other languages
English (en)
Inventor
Yasuharu Saeki
Noritoshi Koyama
Sumio Watanabe
Shigeru Aoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ES2051919T3 publication Critical patent/ES2051919T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)

Abstract

LA PREPARACION PERORAL DE UN COMPUESTO ACIDO INESTABLE COMPRENDE (I) UN NUCLEO QUE CONTENGA EL COMPUESTO ACIDO INESTABLE, (II) UNA PRIMERA CAPA REVESTIDA SOBRE EL NUCLEO, QUE COMPRENDA UN MATERIAL SOLUBLE EN AGUA Y DEPOSITADOR DE UNA PELICULA Y PARTICULAS FINAS DE UNA SUBSTANCIA SOLUBLE EN AGUA, SUSPENDIDAS EN EL MATERIAL Y (III) UNA SEGUNDA CAPA, REVESTIDA SOBRE LA PRIMERA CAPA DE UNA PELICULA ENTERICA. EL COMPUESTO ACIDO INESTABLE ES UN COMPUESTO DE BENZIMIDAZOL.
ES89108492T 1988-05-18 1989-05-11 Preparado para via oral de un compuesto de un acido inestable. Expired - Lifetime ES2051919T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63121233A JPH0768125B2 (ja) 1988-05-18 1988-05-18 酸不安定化合物の内服用製剤

Publications (1)

Publication Number Publication Date
ES2051919T3 true ES2051919T3 (es) 1994-07-01

Family

ID=14806208

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89108492T Expired - Lifetime ES2051919T3 (es) 1988-05-18 1989-05-11 Preparado para via oral de un compuesto de un acido inestable.

Country Status (14)

Country Link
US (1) US5035899A (es)
EP (1) EP0342522B1 (es)
JP (1) JPH0768125B2 (es)
KR (1) KR910002641B1 (es)
AT (1) ATE70442T1 (es)
CA (1) CA1336958C (es)
DD (1) DD283771A5 (es)
DE (1) DE68900566D1 (es)
DK (1) DK174664B1 (es)
ES (1) ES2051919T3 (es)
FI (1) FI93422C (es)
GR (1) GR3003389T3 (es)
HU (1) HU203200B (es)
NO (1) NO178135C (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2094694A1 (es) * 1995-02-01 1997-01-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.

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IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
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US6764697B1 (en) * 1991-06-27 2004-07-20 Alza Corporation System for delaying drug delivery up to seven hours
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SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
CA2193681A1 (en) * 1994-07-08 1996-01-25 Astra Aktiebolag New oral pharmaceutical formulation containing magnesium salt of omeprazole
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US5945124A (en) * 1995-07-05 1999-08-31 Byk Gulden Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole
SE512835C2 (sv) * 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
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JP2004231520A (ja) * 2003-01-28 2004-08-19 Nichiko Pharmaceutical Co Ltd 保存安定性及び溶出速度に優れた医薬組成物
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US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
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GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2094694A1 (es) * 1995-02-01 1997-01-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.

Also Published As

Publication number Publication date
EP0342522B1 (en) 1991-12-18
DD283771A5 (de) 1990-10-24
DE68900566D1 (de) 1992-01-30
KR910002641B1 (ko) 1991-04-27
HUT51896A (en) 1990-06-28
DK239189D0 (da) 1989-05-17
FI891650A0 (fi) 1989-04-06
NO891935D0 (no) 1989-05-12
DK174664B1 (da) 2003-08-18
NO178135B (no) 1995-10-23
FI93422B (fi) 1994-12-30
CA1336958C (en) 1995-09-12
DK239189A (da) 1989-11-19
US5035899A (en) 1991-07-30
NO891935L (no) 1989-11-20
FI891650L (fi) 1989-11-19
ATE70442T1 (de) 1992-01-15
FI93422C (fi) 1995-04-10
GR3003389T3 (en) 1993-02-17
JPH01290628A (ja) 1989-11-22
NO178135C (no) 1996-01-31
JPH0768125B2 (ja) 1995-07-26
EP0342522A1 (en) 1989-11-23
HU203200B (en) 1991-06-28
KR890016964A (ko) 1989-12-14

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