ES2090490T3 - Supositorios de liberacion prolongada y un procedimiento para su preparacion. - Google Patents

Supositorios de liberacion prolongada y un procedimiento para su preparacion.

Info

Publication number
ES2090490T3
ES2090490T3 ES92203989T ES92203989T ES2090490T3 ES 2090490 T3 ES2090490 T3 ES 2090490T3 ES 92203989 T ES92203989 T ES 92203989T ES 92203989 T ES92203989 T ES 92203989T ES 2090490 T3 ES2090490 T3 ES 2090490T3
Authority
ES
Spain
Prior art keywords
weight
supplies
procedure
preparation
ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92203989T
Other languages
English (en)
Inventor
Tjoe Hang Jauw
Hendrik Willem Frijlink
Frits Moolenaar
Peter Meijlink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dagra Pharma BV
Original Assignee
Dagra Pharma BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dagra Pharma BV filed Critical Dagra Pharma BV
Application granted granted Critical
Publication of ES2090490T3 publication Critical patent/ES2090490T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Feed For Specific Animals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Vessels, Lead-In Wires, Accessory Apparatuses For Cathode-Ray Tubes (AREA)

Abstract

UN SUPOSITORIO DE LIBERACION SOSTENIDA QUE CONTIENE EN UNA BASE DE SUPOSITORIO NORMAL A) UNA SUSTANCIA TERAPEUTICAMENTE ACTIVA SOLUBLE EN AGUA, CUYO TAMAÑO DE PARTICULA MEDIO ES MENOR DE 20 (MU)M, B) UNA SUSTANCIA ORGANICA FISIOLOGICAMENTE ACEPTABLE QUE AUMENTA DE VOLUMEN AL ENTRAR EN CONTACTO CON EL AGUA Y C) DIOXIDO SILICICO HIDROFOBICO. LA BASE DEL SUPOSITORIO ES GENERALMENTE UNA GRASA QUE TIENE UN PUNTO DE FUSION DE 29 A 38 (GRADOS) C. COMO INGREDIENTE B) SE PUEDEN UTILIZAR DERIVADOS DE CELULOSA TALES COMO HIDROXIPROPILMETILCELULOSA, EN UNA CANTIDAD DE UN 5 A UN 40% EN PESO, PREFERENTEMENTE DE UN 9 A UN 15% EN PESO. EL INGREDIENTE C) SE UTILIZA PREFERENTEMENTE EN UNA CANTIDAD DE UN 3 A UN 6% EN PESO. TAMBIEN SE DESCRIBE UN PROCESO PARA LA FABRICACION DE LOS SUPOSITORIOS.
ES92203989T 1991-12-20 1992-12-17 Supositorios de liberacion prolongada y un procedimiento para su preparacion. Expired - Lifetime ES2090490T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9102142A NL9102142A (nl) 1991-12-20 1991-12-20 Zetpillen met vertraagde afgifte en werkwijze voor de bereiding daarvan.
CA002099557A CA2099557A1 (en) 1991-12-20 1993-07-02 Sustained release suppositories and a process for preparation

Publications (1)

Publication Number Publication Date
ES2090490T3 true ES2090490T3 (es) 1996-10-16

Family

ID=25676329

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92203989T Expired - Lifetime ES2090490T3 (es) 1991-12-20 1992-12-17 Supositorios de liberacion prolongada y un procedimiento para su preparacion.

Country Status (10)

Country Link
US (1) US5436009A (es)
EP (1) EP0550100B1 (es)
JP (1) JPH05245187A (es)
AT (1) ATE137956T1 (es)
CA (1) CA2099557A1 (es)
DE (1) DE69210787T2 (es)
DK (1) DK0550100T3 (es)
ES (1) ES2090490T3 (es)
GR (1) GR3020828T3 (es)
NL (1) NL9102142A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2288117A (en) * 1994-03-01 1995-10-11 Euro Celtique Sa Sustained release morphine
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US5587224A (en) * 1995-03-27 1996-12-24 Xerox Corporation Developing apparatus including a coated developer roller
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
WO1998000143A1 (en) * 1996-06-28 1998-01-08 Knoll Pharmaceutical Company Slow release pharmaceutical compositions and methods of making same
ATE320796T1 (de) * 1996-12-23 2006-04-15 Sla Pharma Ag Pharmazeutische zubereitung zur behandlung der analinkontinenz und analem juckreiz
US6740333B2 (en) * 2000-07-07 2004-05-25 Anestic Aps Suppository and composition comprising at least one polyethylene glycol
GB0130763D0 (en) * 2001-12-21 2002-02-06 Norgine Res Ltd Treatment methods
US10966924B2 (en) * 2018-09-04 2021-04-06 Babak Ghalili Veterinary cannabinoid, menthol and anesthetic compositions and methods

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2538127A (en) * 1948-02-26 1951-01-16 Searle & Co Medicated suppositories and bases therefor
US3870790A (en) * 1970-01-22 1975-03-11 Forest Laboratories Solid pharmaceutical formulations containing hydroxypropyl methyl cellulose
DE2530563C2 (de) * 1975-07-09 1986-07-24 Bayer Ag, 5090 Leverkusen Analgetische Arzneimittel mit vermindertem Mißbrauchspotential
GB1593261A (en) * 1976-07-23 1981-07-15 Inveresk Res Int Controlled release suppository
US4406883A (en) * 1976-07-23 1983-09-27 Merrell Dow Pharmaceuticals Inc. Controlled release suppositories consisting essentially of a linear polymer particularly, polyvinyl pyrrolidones
JPS6042766B2 (ja) * 1978-12-09 1985-09-25 日本化薬株式会社 基剤
JPS57140710A (en) * 1981-02-24 1982-08-31 Shionogi & Co Ltd Capsule agent for rectal administration
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
CA1207231A (en) * 1982-08-24 1986-07-08 Hans W. Zulliger Medicated suppository
US4999342A (en) * 1988-08-16 1991-03-12 Ortho Pharmaceutical Corporation Long lasting contraceptive suppository composition and methods of use
CH678697A5 (es) * 1989-04-03 1991-10-31 Warner Lambert Co
JPH03170419A (ja) * 1989-11-30 1991-07-24 Torii Yakuhin Kk 塩酸モルヒネの直腸投与製剤

Also Published As

Publication number Publication date
DE69210787T2 (de) 1997-01-02
GR3020828T3 (en) 1996-11-30
JPH05245187A (ja) 1993-09-24
NL9102142A (nl) 1993-07-16
DK0550100T3 (da) 1996-10-14
EP0550100A1 (en) 1993-07-07
EP0550100B1 (en) 1996-05-15
CA2099557A1 (en) 1995-01-03
US5436009A (en) 1995-07-25
DE69210787D1 (de) 1996-06-20
ATE137956T1 (de) 1996-06-15

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