ES2658221T3 - Compuestos útiles en la síntesis de compuestos de benzamida - Google Patents

Compuestos útiles en la síntesis de compuestos de benzamida Download PDF

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Publication number
ES2658221T3
ES2658221T3 ES13846466.4T ES13846466T ES2658221T3 ES 2658221 T3 ES2658221 T3 ES 2658221T3 ES 13846466 T ES13846466 T ES 13846466T ES 2658221 T3 ES2658221 T3 ES 2658221T3
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ES
Spain
Prior art keywords
compounds
formula
cfh2
cf2h
compound
Prior art date
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Active
Application number
ES13846466.4T
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English (en)
Spanish (es)
Inventor
Mario Emilov LOZANOV
Anthony Frank SKUFCA
Andrew George ZEILER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Resverlogix Corp
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Resverlogix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of ES2658221T3 publication Critical patent/ES2658221T3/es
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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/24Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/25Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/38Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES13846466.4T 2012-10-15 2013-10-09 Compuestos útiles en la síntesis de compuestos de benzamida Active ES2658221T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261713711P 2012-10-15 2012-10-15
US201261713711P 2012-10-15
PCT/IB2013/003031 WO2014060852A2 (en) 2012-10-15 2013-10-09 Compounds useful in the synthesis of benzamide compounds

Publications (1)

Publication Number Publication Date
ES2658221T3 true ES2658221T3 (es) 2018-03-08

Family

ID=50475926

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13846466.4T Active ES2658221T3 (es) 2012-10-15 2013-10-09 Compuestos útiles en la síntesis de compuestos de benzamida

Country Status (25)

Country Link
US (1) US8884046B2 (pt)
EP (1) EP2906531B1 (pt)
JP (2) JP6307087B2 (pt)
KR (1) KR101532570B1 (pt)
CN (1) CN104884427B (pt)
AU (1) AU2013333575B2 (pt)
BR (1) BR112015008389B1 (pt)
CA (1) CA2888378C (pt)
CY (1) CY1119862T1 (pt)
DK (1) DK2906531T3 (pt)
ES (1) ES2658221T3 (pt)
HR (1) HRP20180176T1 (pt)
HU (1) HUE036421T2 (pt)
IL (2) IL238186A (pt)
LT (1) LT2906531T (pt)
MX (1) MX338885B (pt)
NO (1) NO2992016T3 (pt)
NZ (1) NZ707276A (pt)
PL (1) PL2906531T3 (pt)
PT (1) PT2906531T (pt)
RS (1) RS56846B1 (pt)
RU (1) RU2593752C1 (pt)
SA (1) SA515360284B1 (pt)
SI (1) SI2906531T1 (pt)
WO (1) WO2014060852A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008092231A1 (en) 2007-02-01 2008-08-07 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
AU2010204106B2 (en) 2009-01-08 2014-05-08 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
KR20190091564A (ko) 2009-04-22 2019-08-06 리스버로직스 코퍼레이션 신규한 소염제
RU2640115C2 (ru) 2011-11-01 2017-12-26 Ресверлоджикс Корп. Фармацевтические композиции замещенных хиназолинонов
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
AU2013365926B9 (en) 2012-12-21 2019-01-17 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
JO3789B1 (ar) 2015-03-13 2021-01-31 Resverlogix Corp التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0118752D0 (en) * 2001-08-01 2001-09-26 Pfizer Ltd Process for the production of quinazolines
GB0206033D0 (en) * 2002-03-14 2002-04-24 Pfizer Ltd Compounds useful in therapy
US20050080021A1 (en) 2002-08-15 2005-04-14 Joseph Tucker Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders
US20040033480A1 (en) 2002-08-15 2004-02-19 Wong Norman C.W. Use of resveratrol to regulate expression of apolipoprotein A1
US20050080024A1 (en) 2002-08-15 2005-04-14 Joseph Tucker Nitric oxide donating derivatives for the treatment of cardiovascular disorders
CN1925862A (zh) 2003-10-10 2007-03-07 雷斯弗洛吉克斯公司 与egr-1增强子元件有关的疾病的治疗
GB0512324D0 (en) * 2005-06-16 2005-07-27 Novartis Ag Organic compounds
WO2006045010A2 (en) 2004-10-20 2006-04-27 Resverlogix Corp. Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
CA2617213C (en) 2005-07-29 2014-01-28 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
WO2008092231A1 (en) 2007-02-01 2008-08-07 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
WO2008157575A1 (en) * 2007-06-21 2008-12-24 Irm Llc Protein kinase inhibitors and methods for using thereof
KR101629356B1 (ko) 2008-06-26 2016-06-13 리스버로직스 코퍼레이션 퀴나졸리논 유도체의 제조방법
AU2010204106B2 (en) 2009-01-08 2014-05-08 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
NZ755378A (en) 2009-03-18 2022-07-29 Resverlogix Corp Novel quinazolinones and related compounds for use as anti-inflammatory agents
KR20190091564A (ko) 2009-04-22 2019-08-06 리스버로직스 코퍼레이션 신규한 소염제
GB201007286D0 (en) * 2010-04-30 2010-06-16 Astex Therapeutics Ltd New compounds
DE102010048800A1 (de) * 2010-10-20 2012-05-10 Merck Patent Gmbh Chinoxalinderivate
RU2640115C2 (ru) 2011-11-01 2017-12-26 Ресверлоджикс Корп. Фармацевтические композиции замещенных хиназолинонов
ES2664050T3 (es) * 2012-10-15 2018-04-18 Albemarle Corporation Procesos para la síntesis de la 2-amino-4,6-dimetoxibenzamida y otros compuestos de benzamida
TWI641936B (zh) * 2012-11-13 2018-11-21 美商慧盛材料美國責任有限公司 漿料供應及/或化學品摻合物供應設備、方法、使用方法及製造方法

Also Published As

Publication number Publication date
HUE036421T2 (hu) 2018-07-30
NO2992016T3 (pt) 2018-03-17
CN104884427A (zh) 2015-09-02
BR112015008389B1 (pt) 2020-12-15
MX2015004764A (es) 2015-08-14
CA2888378A1 (en) 2014-04-24
SA515360284B1 (ar) 2016-04-19
NZ707276A (en) 2016-02-26
CN104884427B (zh) 2016-09-07
EP2906531B1 (en) 2018-01-17
PL2906531T3 (pl) 2018-04-30
WO2014060852A2 (en) 2014-04-24
DK2906531T3 (en) 2018-02-05
CA2888378C (en) 2015-09-22
JP2015531403A (ja) 2015-11-02
JP2017088632A (ja) 2017-05-25
AU2013333575B2 (en) 2015-07-16
HRP20180176T1 (hr) 2018-03-09
LT2906531T (lt) 2018-02-26
US8884046B2 (en) 2014-11-11
AU2013333575A1 (en) 2015-05-28
RS56846B1 (sr) 2018-04-30
CY1119862T1 (el) 2018-06-27
WO2014060852A3 (en) 2014-07-24
KR20150061661A (ko) 2015-06-04
HK1207623A1 (en) 2016-02-05
SI2906531T1 (en) 2018-03-30
IL244099A0 (en) 2016-04-21
JP6307087B2 (ja) 2018-04-04
EP2906531A2 (en) 2015-08-19
BR112015008389A2 (pt) 2017-07-04
MX338885B (es) 2016-05-04
RU2593752C1 (ru) 2016-08-10
IL238186A (en) 2016-03-31
EP2906531A4 (en) 2016-06-01
PT2906531T (pt) 2018-02-06
US20140107369A1 (en) 2014-04-17
KR101532570B1 (ko) 2015-06-30

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