ES2973524T3 - Métodos para mejorar la eficacia de la transducción de vectores en los linfocitos T - Google Patents
Métodos para mejorar la eficacia de la transducción de vectores en los linfocitos T Download PDFInfo
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- ES2973524T3 ES2973524T3 ES20176483T ES20176483T ES2973524T3 ES 2973524 T3 ES2973524 T3 ES 2973524T3 ES 20176483 T ES20176483 T ES 20176483T ES 20176483 T ES20176483 T ES 20176483T ES 2973524 T3 ES2973524 T3 ES 2973524T3
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- C12N2740/00—Reverse transcribing RNA viruses
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- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15042—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
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| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| EP3608022A1 (en) | 2013-03-15 | 2020-02-12 | The Trustees of Princeton University | Methods and devices for high throughput purification |
| EP3569313A1 (en) | 2013-03-15 | 2019-11-20 | GPB Scientific, LLC | On-chip microfluidic processing of particles |
| US12590955B2 (en) | 2013-03-15 | 2026-03-31 | Zeon Corporation | Methods and systems for processing particles |
| JP6754761B2 (ja) * | 2014-07-11 | 2020-09-16 | セルジーン コーポレイション | Ｔリンパ球へのベクター導入効率の改善方法 |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| EP3675876A4 (en) | 2017-09-01 | 2021-06-02 | GPB Scientific, Inc. | METHOD FOR PRODUCING THERAPEUTICALLY ACTIVE CELLS USING MICROFLUIDICS |
| DE102018100967B4 (de) | 2018-01-17 | 2019-08-14 | Immatics US, Inc. | Verfahren zur feststellung der wirksamkeit von viralen vektoren |
| DE102018010282A1 (de) | 2018-01-17 | 2019-07-18 | Immatics US, Inc. | Verfahren zur Feststellung der Wirksamkeit von viralen Vektoren |
| CN108715865B (zh) * | 2018-05-28 | 2021-09-21 | 福建师范大学 | 用于提高细胞转染效率的试剂组合物 |
| US20220267726A1 (en) | 2019-07-18 | 2022-08-25 | Gpb Scientific, Inc. | Ordered processing of blood products to produce therapeutically active cells |
| US20230028754A1 (en) | 2019-12-28 | 2023-01-26 | Gpb Scientific, Inc. | Microfluidic cartridges for processing particles and cells |
| EP4320226A4 (en) * | 2021-04-06 | 2025-08-06 | Unicet Biotech Llc | METHODS FOR IMPROVING THE STABILITY OF VIRAL TRANSDUCTION OF GAMMA DELTA T CELLS AND RELATED APPLICATIONS |
| WO2023286088A1 (en) * | 2021-07-16 | 2023-01-19 | Indian Institute Of Science Education And Research Bhopal | Methods and compositions for viral vector transduction |
| WO2025180499A1 (zh) * | 2024-02-28 | 2025-09-04 | 南京因领生物科技有限公司 | 一种提高细胞中病毒包装产量或质量的方法 |
| CN119530302B (zh) * | 2025-01-22 | 2025-06-27 | 青岛华赛伯曼医学细胞生物有限公司 | 提高til细胞的慢病毒转导效率及转导稳定性的方法及试剂盒 |
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| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US5665577A (en) | 1989-02-06 | 1997-09-09 | Dana-Farber Cancer Institute | Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof |
| US8211422B2 (en) | 1992-03-18 | 2012-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric receptor genes and cells transformed therewith |
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| WO1996034970A1 (en) * | 1995-05-04 | 1996-11-07 | United States Of America, Represented By The Secretary Of The Navy | Improved methods for transfecting t cells |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| US5948893A (en) | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| EP1849873B1 (en) | 1999-04-29 | 2011-10-12 | Gbp Ip, Llc | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| EP2316918B1 (en) | 2001-02-14 | 2015-07-01 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| US20060210536A1 (en) * | 2003-04-17 | 2006-09-21 | Curt Horvath | Methods and compositions for inhibiting stat signaling pathways |
| ATE488252T1 (de) * | 2003-05-05 | 2010-12-15 | Virxsys Corp | Erhöhte transduktion mit abc- transportersubstratenhemmern |
| AU2006214278C1 (en) * | 2005-02-16 | 2012-07-19 | Miltenyi Biotec Technology, Inc. | Lentiviral vectors and their use |
| GB0526255D0 (en) | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| PL2471907T3 (pl) | 2005-12-29 | 2019-07-31 | Celularity, Inc. | Populacje komórek macierzystych łożyska |
| JP5666903B2 (ja) * | 2007-05-23 | 2015-02-12 | サンガモ バイオサイエンシーズ， インコーポレイテッド | 導入遺伝子の発現を増強するための方法および組成物 |
| RU2536242C2 (ru) | 2007-09-28 | 2014-12-20 | Антродженезис Корпорейшн | Угнетение опухолей с помощью плацентарного перфузата человека и выделенных из плаценты человека вспомогательных натуральных клеток-киллеров |
| RU2015130665A (ru) | 2008-11-19 | 2018-12-24 | Антродженезис Корпорейшн | Амниотические адгезивные клетки |
| MX342995B (es) | 2010-07-13 | 2016-10-21 | Anthrogenesis Corp | Métodos de generar células asesinas naturales. |
| WO2012072096A1 (en) | 2010-12-03 | 2012-06-07 | Biontech Ag | Method for cellular rna expression |
| DK3763820T3 (da) * | 2012-02-29 | 2022-02-07 | Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh | Retroviral transduktion ved hjælp af poloxamerer |
| EA033110B1 (ru) * | 2012-04-11 | 2019-08-30 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Химерный рецептор антигена, направленный на антиген созревания b-клеток, кодирующая его нуклеиновая кислота, соответствующие экспрессионный вектор, клетка-хозяин, применения и способы |
| WO2014046617A1 (en) * | 2012-09-19 | 2014-03-27 | Agency For Science, Technology And Research | Compositions and methods for treating cancer |
| JP6754761B2 (ja) * | 2014-07-11 | 2020-09-16 | セルジーン コーポレイション | Ｔリンパ球へのベクター導入効率の改善方法 |
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