ES531896A0 - Procedimiento para producir hormona de crecimiento de humano - Google Patents

Procedimiento para producir hormona de crecimiento de humano

Info

Publication number
ES531896A0
ES531896A0 ES531896A ES531896A ES531896A0 ES 531896 A0 ES531896 A0 ES 531896A0 ES 531896 A ES531896 A ES 531896A ES 531896 A ES531896 A ES 531896A ES 531896 A0 ES531896 A0 ES 531896A0
Authority
ES
Spain
Prior art keywords
procedure
growth hormone
human growth
producing human
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES531896A
Other languages
English (en)
Other versions
ES8602136A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ES531896A0 publication Critical patent/ES531896A0/es
Publication of ES8602136A1 publication Critical patent/ES8602136A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/12Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/30Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES531896A 1983-04-25 1984-04-25 Procedimiento para producir hormona de crecimiento de humano Expired ES8602136A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/488,232 US4755465A (en) 1983-04-25 1983-04-25 Secretion of correctly processed human growth hormone in E. coli and Pseudomonas

Publications (2)

Publication Number Publication Date
ES531896A0 true ES531896A0 (es) 1985-12-01
ES8602136A1 ES8602136A1 (es) 1985-12-01

Family

ID=23938879

Family Applications (1)

Application Number Title Priority Date Filing Date
ES531896A Expired ES8602136A1 (es) 1983-04-25 1984-04-25 Procedimiento para producir hormona de crecimiento de humano

Country Status (9)

Country Link
US (1) US4755465A (es)
EP (1) EP0127305A1 (es)
JP (2) JPS6045595A (es)
CA (1) CA1267099A (es)
DK (1) DK204684A (es)
ES (1) ES8602136A1 (es)
IL (1) IL71622A (es)
NZ (1) NZ207924A (es)
ZA (1) ZA843062B (es)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK55685A (da) * 1985-02-07 1986-08-08 Nordisk Gentofte Enzym eller enzymkompleks med proteolytisk aktivitet
US5618697A (en) * 1982-12-10 1997-04-08 Novo Nordisk A/S Process for preparing a desired protein
US4859600A (en) * 1983-04-25 1989-08-22 Genentech, Inc. Recombinant procaryotic cell containing correctly processed human growth hormone
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
BG49718A3 (bg) * 1983-07-15 1992-01-15 Bio- Technology General Corp Метод за получаване на полипептид със супероксиддисмутазна активност
DE122004000009I1 (de) * 1984-08-16 2004-11-18 Savient Pharmaceuticals Inc Methode zur Herstellung von menschlichen Wachstumshormonen.
IL76360A0 (en) * 1984-09-26 1986-01-31 Takeda Chemical Industries Ltd Mutual separation of proteins
US5853978A (en) * 1985-12-04 1998-12-29 Genentech, Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and methods of use
US6534285B1 (en) * 1984-12-24 2003-03-18 Genentech, Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use
US4861868A (en) 1985-02-22 1989-08-29 Monsanto Company Production of proteins in procaryotes
DK151585D0 (da) * 1985-04-03 1985-04-03 Nordisk Gentofte Dna-sekvens
US4786501A (en) * 1985-07-15 1988-11-22 International Minerals & Chemical Corp. Cylindrical implants for the controlled release of growth hormones
US5013662A (en) * 1985-09-20 1991-05-07 Cetus Corporation Bacterial methionine n-terminal peptidase
US4870017A (en) * 1985-09-20 1989-09-26 Cetus Corporation Bacterial methionine N-terminal peptidase
US4865974A (en) * 1985-09-20 1989-09-12 Cetus Corporation Bacterial methionine N-terminal peptidase
FR2597114B1 (fr) * 1986-04-10 1994-02-25 Sanofi Procede microbiologique pour l'obtention d'une proteine par culture d'une souche bacterienne mutante
FR2599753B1 (fr) * 1986-06-05 1989-12-08 Sanofi Sa Sequence d'adn composite et son application pour la production de l'hormone de croissance
IT1228925B (it) * 1987-08-07 1991-07-10 Eniricerche Spa Procedimento per la preparazione dell'ormone della crescita umano
US5744139A (en) * 1991-06-28 1998-04-28 University Of Tennessee Research Corporation Insulin-like growth factor I (IGF-1) induced improvement of depressed T4/T8 ratios
US5202119A (en) * 1991-06-28 1993-04-13 Genentech, Inc. Method of stimulating immune response
US5317012A (en) * 1991-10-04 1994-05-31 The University Of Tennessee Research Corporation Human growth hormone induced improvement in depressed T4/T8 ratio
JPH06503479A (ja) * 1991-10-16 1994-04-21 オラージェン, インコーポレイテッド 動物体細胞の粒子−媒介トランスフォーメーション
JPH07118577B2 (ja) * 1992-12-02 1995-12-18 株式会社リコー 電子装置用基板の検査方法
GB9526733D0 (en) 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
MX9605082A (es) 1996-10-24 1998-04-30 Univ Autonoma De Nuevo Leon Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
PH12012502440A1 (en) * 2001-06-26 2013-06-17 Amgen Inc Antibodies to opgl
JP4580644B2 (ja) * 2001-07-06 2010-11-17 エルジー ライフ サイエンシズ エルティーディー. バチルスリケニフォルミス由来の新規アミノペプチダーゼ、該アミノペプチダーゼをコードする遺伝子、該遺伝子を含む発現ベクター、該発現ベクターによる形質転換体及び該発現ベクターを利用する天然型蛋白質の製造方法
MXPA04007886A (es) 2002-02-13 2004-10-15 Dow Global Technologies Inc Sobre-expresion de genes de extremozimo en pseudomonadas y bacterias estrechamente relacionadas.
DE60332358D1 (de) * 2002-09-09 2010-06-10 Hanall Pharmaceutical Co Ltd Protease-resistente modifizierte interferon alpha polypeptide
US9453251B2 (en) * 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
NZ543976A (en) * 2003-05-09 2008-04-30 Pharmexa As Immunogenic human TNF alpha analogues with reduced cytotoxicity and methods of their preparation
CA2534055A1 (en) * 2003-08-01 2005-02-10 Genentech, Inc. Antibody cdr polypeptide sequences with restricted diversity
CA2545610C (en) 2003-11-19 2014-03-25 Dow Global Technolgies Inc. Auxotrophic pseudomonas fluorescens bacteria for recombinant protein expression
AU2004317306B2 (en) 2003-11-21 2010-09-02 Pelican Technology Holdings, Inc. Improved expression systems with Sec-system secretion
EP1758925A4 (en) * 2003-12-01 2009-04-08 Dow Global Technologies Inc PRODUCTION OF A RECOMBINANT ICOSAHEDRIC VIRUS LIKE PARTICLE
ES2663594T3 (es) 2004-01-16 2018-04-16 Pfenex Inc Expresión de proteínas de mamífero en Pseudomonas fluorescens
EP2327724A3 (en) * 2004-02-02 2011-07-27 Ambrx, Inc. Modified human growth hormone polypeptides and their uses
KR101699142B1 (ko) * 2004-06-18 2017-01-23 암브룩스, 인코포레이티드 신규 항원-결합 폴리펩티드 및 이의 용도
CA2558760A1 (en) * 2004-06-23 2006-01-05 Usv Limited Chimeric human growth hormone derived from the placenta and pituitary isoform and processes for obtaining said chimera
JP2008507280A (ja) * 2004-07-21 2008-03-13 アンブレツクス・インコーポレイテツド 非天然コードアミノ酸を用いた生合成ポリペプチド
US8603824B2 (en) 2004-07-26 2013-12-10 Pfenex, Inc. Process for improved protein expression by strain engineering
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
CN102732588B (zh) * 2004-12-22 2015-01-07 Ambrx公司 氨酰基-tRNA合成酶的组合物及其用途
JP2008525473A (ja) 2004-12-22 2008-07-17 アンブレツクス・インコーポレイテツド 修飾されたヒト成長ホルモン
US7816320B2 (en) 2004-12-22 2010-10-19 Ambrx, Inc. Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35
GB2438760A (en) * 2004-12-22 2007-12-05 Ambrx Inc Methods for expression and purification of recombinant human growth hormone
WO2006133089A2 (en) * 2005-06-03 2006-12-14 Ambrx, Inc. Improved human interferon molecules and their uses
MX2008002149A (es) 2005-08-18 2008-04-22 Ambrx Inc Composiciones de arnt y sus usos.
EP1957531B1 (en) 2005-11-07 2016-04-13 Genentech, Inc. Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
CN104710503B (zh) * 2005-11-08 2023-04-25 Ambrx 公司 用于修饰非天然氨基酸和非天然氨基酸多肽的促进剂
EP1951890A4 (en) * 2005-11-16 2009-06-24 Ambrx Inc PROCESSES AND COMPOSITIONS WITH NON-NATURAL AMINO ACIDS
WO2007064919A2 (en) * 2005-12-02 2007-06-07 Genentech, Inc. Binding polypeptides with restricted diversity sequences
AU2006338198B2 (en) * 2005-12-02 2012-04-26 Genentech, Inc. Binding polypeptides and uses thereof
DK1968635T3 (en) * 2005-12-14 2014-12-15 Ambrx Inc Compositions and Methods of, and uses of non-natural amino acids and polypeptides
EP2064333B1 (en) * 2006-09-08 2014-02-26 Ambrx, Inc. Suppressor trna transcription in vertebrate cells
MX2009002460A (es) * 2006-09-08 2009-03-20 Ambrx Inc Arnt supresor hibrido para celulas de vertebrados.
CN106008699A (zh) 2006-09-08 2016-10-12 Ambrx公司 经修饰的人类血浆多肽或Fc骨架和其用途
JP5714230B2 (ja) 2007-01-31 2015-05-07 フェネックス インコーポレイテッド 発現上昇のための細菌リーダー配列
CA2682147C (en) 2007-03-30 2017-08-08 Ambrx, Inc. Modified fgf-21 polypeptides and their uses
WO2009014782A2 (en) * 2007-04-27 2009-01-29 Dow Global Technologies Inc. Improved production and in vivo assembly of soluble recombinant icosahedral virus-like particles
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
JP5444553B2 (ja) 2007-04-27 2014-03-19 フェネックス インコーポレイテッド 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および/または質が改善されている特定の株を同定する方法
MX2009011870A (es) * 2007-05-02 2009-11-12 Ambrx Inc Polipeptidos de interferon beta modificados y usos de los mismos.
MX2010005317A (es) * 2007-11-20 2010-06-02 Ambrx Inc Polipeptidos de insulina modificados y sus usos.
NZ586947A (en) 2008-02-08 2012-11-30 Ambrx Inc Modified leptin polypeptides and their uses
EP2285965A1 (en) * 2008-03-31 2011-02-23 Pfenex Inc A design for rapidly cloning one or more polypeptide chains into an expression system
PT2318029T (pt) * 2008-07-23 2018-01-10 Ambrx Inc Polipéptidos de g-csf bovino modificados e suas utilizações
PE20110480A1 (es) 2008-09-26 2011-07-01 Ambrx Inc Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales
MX2011003272A (es) 2008-09-26 2011-04-28 Ambrx Inc Polipeptidos de eritropoyetina animal modificados y sus usos.
WO2010132341A2 (en) 2009-05-11 2010-11-18 Pfenex, Inc. Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of non-natural amino acids therein
WO2011109556A2 (en) * 2010-03-04 2011-09-09 Pfenex Inc. Method for producing soluble recombinant interferon protein without denaturing
EP2553102B1 (en) 2010-03-30 2015-12-09 Pfenex Inc. High level expression of recombinant toxin proteins
NZ603033A (en) 2010-04-01 2014-06-27 Pfenex Inc Methods for g-csf production in a pseudomonas host cell
MA34521B1 (fr) 2010-08-17 2013-09-02 Ambrx Inc Polypeptides de relaxine modifiés et leurs utilisations
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
TWI480288B (zh) 2010-09-23 2015-04-11 Lilly Co Eli 牛顆粒細胞群落刺激因子及其變體之調配物
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
SMT202100388T1 (it) 2014-10-24 2021-09-14 Bristol Myers Squibb Co Polipeptidi fgf-21 modificati e loro usi
US10280409B2 (en) 2014-11-20 2019-05-07 Biological E Limited Codon optimized polynucleotide for high level expression of CRM197
JP6817939B2 (ja) 2014-12-01 2021-01-20 フェネックス インク. ペプチド産生のための融合パートナー
CN110637027B (zh) 2017-02-08 2024-08-30 百时美施贵宝公司 包含药代动力学增强子的修饰的松弛素多肽及其用途
JP7784804B2 (ja) 2017-10-27 2025-12-12 フェネックス インク. 組み換えerwiniaアスパラギナーゼの製造のための方法
AU2018354069A1 (en) 2017-10-27 2020-06-11 Pelican Technology Holdings, Inc. Bacterial leader sequences for periplasmic protein expression
WO2019083794A1 (en) 2017-10-27 2019-05-02 Pfenex Inc. PROCESS FOR PRODUCING EAR ASPARAGINASE. RECOMBINED COLI
US20220227805A1 (en) 2020-12-23 2022-07-21 Jazz Pharmaceuticals Ireland Ltd. Methods of purifying charge-shielded fusion proteins
WO2022211829A1 (en) 2021-03-30 2022-10-06 Jazz Pharmaceuticals Ireland Ltd. Dosing of recombinant l-asparaginase

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52036B1 (en) * 1979-05-24 1987-05-27 Univ California Non-passageable viruses
GR68404B (es) * 1979-06-01 1981-12-29 Univ California
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US4338397A (en) * 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
FI64813C (fi) * 1980-12-31 1984-01-10 Ilkka Antero Palva Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer
GR76959B (es) * 1981-01-02 1984-09-04 Univ New York State Res Found
US4775622A (en) * 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
DE3380262D1 (en) * 1982-05-25 1989-08-31 Lilly Co Eli Cloning vectors for expression of exogenous protein
JPS59135892A (ja) * 1983-01-25 1984-08-04 Kunio Yamane シグナルアミノ酸配列をコードするdna

Also Published As

Publication number Publication date
IL71622A (en) 1990-03-19
IL71622A0 (en) 1984-07-31
ZA843062B (en) 1984-11-28
JPS6045595A (ja) 1985-03-12
EP0127305A1 (en) 1984-12-05
NZ207924A (en) 1988-03-30
ES8602136A1 (es) 1985-12-01
DK204684D0 (da) 1984-04-24
US4755465A (en) 1988-07-05
CA1267099A (en) 1990-03-27
DK204684A (da) 1984-10-26
JPH05252936A (ja) 1993-10-05
AU2721984A (en) 1984-11-01
AU586609B2 (en) 1989-07-20

Similar Documents

Publication Publication Date Title
ES531896A0 (es) Procedimiento para producir hormona de crecimiento de humano
ES499043A0 (es) Un metodo para producir la hormona de crecimiento humano
IT1178429B (it) Procedimento per produrre 5-idrossi-metilfurfurale
FI890893L (fi) Menetelmä follikkelia stimuloivan hormonin valmistamiseksi
ATA279184A (de) Chirurgisches implantat
BR8707937A (pt) Protese para osteosintese
ES533260A0 (es) Procedimiento para la preparacion de 13a-alquilgonanos
ES548323A0 (es) Procedimiento para preparar derivados de benzodifuranona
ES537992A0 (es) Procedimiento para preparar 2-fenil-imidazoles
ES533995A0 (es) Procedimiento para preparar imidasoles
ES533538A0 (es) Procedimiento para la obtencion de tetrahidropiridazinonas
ES538621A0 (es) Procedimiento para la preparacion de fenolsulfonftaleinil-b-d-galactosidos
ES532572A0 (es) Procedimiento para la preparacion de n-piridilindoles
ES536780A0 (es) Procedimiento de preparar nuevas bencensulfonil-lactamas
ES549975A0 (es) Procedimiento para preparar n-formil-&-aspartil fenilalanina
ES534227A0 (es) Procedimiento para preparar piridinas
MX156242A (es) Procedimiento para la preparacion de eter-sulfonatos
IT1177343B (it) Procedimento per produrre 4-alcossianiline
ES534800A0 (es) Procedimiento para preparar ciclopeptidos
ES533988A0 (es) Procedimiento para la obtencion de mercaptocarboxilamidas
ES546110A0 (es) Procedimiento de producir factor viii-r humano
ES530037A0 (es) Procedimiento para preparar imidazolamidas
ES533024A0 (es) Procedimiento para preparar meta-o para-isopropenil-alfa-alfa-dimetilbencilamina
ES528114A0 (es) Procedimiento para la preparacion de hexanorbrassinolid-22-eteres
ES537129A0 (es) Procedimiento para la obtencion de iodacetamidas

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050912