ES8101534A1 - Procedimiento para la preparacion de un nuevo derivado del acido 2-(4-isobutilfenil)-propionico - Google Patents
Procedimiento para la preparacion de un nuevo derivado del acido 2-(4-isobutilfenil)-propionicoInfo
- Publication number
- ES8101534A1 ES8101534A1 ES80488563A ES488563A ES8101534A1 ES 8101534 A1 ES8101534 A1 ES 8101534A1 ES 80488563 A ES80488563 A ES 80488563A ES 488563 A ES488563 A ES 488563A ES 8101534 A1 ES8101534 A1 ES 8101534A1
- Authority
- ES
- Spain
- Prior art keywords
- isobutylphenyl
- propionic acid
- novel derivative
- preparation
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical class CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 title abstract 3
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 230000003356 anti-rheumatic effect Effects 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 150000003751 zinc Chemical class 0.000 abstract 1
- CLRAXVJLBLYFHG-UHFFFAOYSA-L zinc;2-[4-(2-methylpropyl)phenyl]propanoate Chemical compound [Zn+2].CC(C)CC1=CC=C(C(C)C([O-])=O)C=C1.CC(C)CC1=CC=C(C(C)C([O-])=O)C=C1 CLRAXVJLBLYFHG-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DEL 2-(4-ISOBUTILFENIL)-PROPIONATO DE ZINC. CONSISTE EN HACER REACCIONAR UNA SAL DE ZIC CON ACIDO 2-(4-ISOBUTILFENIL)-PROPIONICO EN PROPORCIONES APROXIMADAMENTE ESTEQUIOMETRICAS. LA REACCION SE EFECTUA EN UN MEDIO DISOLVENTE POLAR Y A UNA TEMPERATURA COMPRENDIDA ENTRE 50 Y 100GC. LA REACCION SE MANTIENE A REFLUJO DURANTE 10-45 MINUTOS EN AGITACION. EL 2-(4-ISOBUTILFENIL)-PROPIONATO DE ZINC SE OBTIENE EL ENFRIAR EL CONCENTRADO. EL DISOLVENTE EMPLEADO ES ALCOHOL. N
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES80488563A ES8101534A1 (es) | 1980-02-14 | 1980-02-14 | Procedimiento para la preparacion de un nuevo derivado del acido 2-(4-isobutilfenil)-propionico |
| IT67171/81A IT1146741B (it) | 1980-02-14 | 1981-02-06 | Derivato dell acido 7 4 isobutilfenil propionico particolarmente utile come antinfiammatorio e procedimento per la sua preparazione |
| BE0/203763A BE887469A (fr) | 1980-02-14 | 1981-02-11 | 2-(4-isobutylphenyl)-propionate de zinc, sa preparation et son utilisation |
| NL8100720A NL8100720A (nl) | 1980-02-14 | 1981-02-13 | Derivaat van 2-<4-isobutylfenyl>-propionzuur; farmaceutisch preparaat; werkwijze voor de bereiding van het derivaat. |
| DE3105357A DE3105357C2 (de) | 1980-02-14 | 1981-02-13 | Zinksalz der 2-(Isobutylphenyl)-propionsäure, dessen Herstellung und Arzneimittel auf dessen Basis |
| CH96581A CH646132A5 (fr) | 1980-02-14 | 1981-02-13 | Procede de preparation d'un derive de l'acide 2-(4-isobutylphenyl)-propionique. |
| FR8103240A FR2476069A1 (fr) | 1980-02-14 | 1981-02-13 | Procede de preparation d'un derive nouveau de l'acide 2-(4-isobutylphenyl)-propionique |
| KR1019810000461A KR830005094A (ko) | 1980-02-14 | 1981-02-14 | 2-(4-이소부틸페닐)-프로피온산 유도체의 제조 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES80488563A ES8101534A1 (es) | 1980-02-14 | 1980-02-14 | Procedimiento para la preparacion de un nuevo derivado del acido 2-(4-isobutilfenil)-propionico |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES488563A0 ES488563A0 (es) | 1980-12-16 |
| ES8101534A1 true ES8101534A1 (es) | 1980-12-16 |
Family
ID=8479811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES80488563A Expired ES8101534A1 (es) | 1980-02-14 | 1980-02-14 | Procedimiento para la preparacion de un nuevo derivado del acido 2-(4-isobutilfenil)-propionico |
Country Status (8)
| Country | Link |
|---|---|
| KR (1) | KR830005094A (es) |
| BE (1) | BE887469A (es) |
| CH (1) | CH646132A5 (es) |
| DE (1) | DE3105357C2 (es) |
| ES (1) | ES8101534A1 (es) |
| FR (1) | FR2476069A1 (es) |
| IT (1) | IT1146741B (es) |
| NL (1) | NL8100720A (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3938227C1 (en) * | 1989-11-17 | 1991-05-02 | Dolorgiet Gmbh & Co Kg, 5205 St Augustin, De | Oral antiinflammatory and analgetic pharmaceutical compsn. - comprises magnesium ibuprofen dissolved in mixt. of water, propane-1,2-diol and glycerol |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1059677B (it) * | 1974-03-22 | 1982-06-21 | Neopharmed Spa | Sale di lisina ad azione terapeutica |
-
1980
- 1980-02-14 ES ES80488563A patent/ES8101534A1/es not_active Expired
-
1981
- 1981-02-06 IT IT67171/81A patent/IT1146741B/it active
- 1981-02-11 BE BE0/203763A patent/BE887469A/fr not_active IP Right Cessation
- 1981-02-13 CH CH96581A patent/CH646132A5/fr not_active IP Right Cessation
- 1981-02-13 DE DE3105357A patent/DE3105357C2/de not_active Expired
- 1981-02-13 NL NL8100720A patent/NL8100720A/nl not_active Application Discontinuation
- 1981-02-13 FR FR8103240A patent/FR2476069A1/fr active Granted
- 1981-02-14 KR KR1019810000461A patent/KR830005094A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CH646132A5 (fr) | 1984-11-15 |
| FR2476069A1 (fr) | 1981-08-21 |
| BE887469A (fr) | 1981-06-01 |
| DE3105357C2 (de) | 1983-09-01 |
| ES488563A0 (es) | 1980-12-16 |
| IT8167171A0 (it) | 1981-02-06 |
| FR2476069B1 (es) | 1983-05-06 |
| KR830005094A (ko) | 1983-07-23 |
| NL8100720A (nl) | 1981-09-16 |
| DE3105357A1 (de) | 1982-01-14 |
| IT1146741B (it) | 1986-11-19 |
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