ES8104296A1 - Procedimiento para preparar derivados de morfonas y normor- fonas - Google Patents

Procedimiento para preparar derivados de morfonas y normor- fonas

Info

Publication number: ES8104296A1
Authority: ES; Spain
Prior art keywords: preparation; intermediate compounds; derivatives; morphine derivatives; formula
Prior art date: 1979-08-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES494122A

Other languages

English (en)

Spanish (es)

Other versions

ES494122A0 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mallinckrodt Inc

Original Assignee

Mallinckrodt Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-08-09

Filing date

1980-08-08

Publication date

1981-04-16

1980-08-08 Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc

1981-04-16 Publication of ES8104296A1 publication Critical patent/ES8104296A1/es

1981-04-16 Publication of ES494122A0 publication Critical patent/ES494122A0/es

Status Granted legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 title 1
BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical class O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 title 1
230000017858 demethylation Effects 0.000 abstract 2
238000010520 demethylation reaction Methods 0.000 abstract 2
239000004215 Carbon black (E152) Substances 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
150000001639 boron compounds Chemical class 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
150000002430 hydrocarbons Chemical group 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
239000012429 reaction media Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ES494122A 1979-08-09 1980-08-08 Procedimiento para preparar derivados de morfonas y normor- fonas Granted ES494122A0 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US6527579A	1979-08-09	1979-08-09

Publications (2)

Publication Number	Publication Date
ES8104296A1 true ES8104296A1 (es)	1981-04-16
ES494122A0 ES494122A0 (es)	1981-04-16

Family

ID=22061564

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES494122A Granted ES494122A0 (es)	1979-08-09	1980-08-08	Procedimiento para preparar derivados de morfonas y normor- fonas

Country Status (16)

Country	Link
JP (1)	JPS56501010A (fr)
AU (1)	AU6116580A (fr)
BE (1)	BE884671A (fr)
DD (1)	DD154541A5 (fr)
DK (1)	DK151781A (fr)
ES (1)	ES494122A0 (fr)
FI (1)	FI802479A7 (fr)
FR (1)	FR2465735A1 (fr)
GB (1)	GB2066256A (fr)
IL (1)	IL60783A0 (fr)
IT (1)	IT8068267A0 (fr)
NL (1)	NL8020319A (fr)
NO (1)	NO802139L (fr)
PL (1)	PL226162A1 (fr)
SE (1)	SE8102214L (fr)
WO (1)	WO1981000409A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4795813A (en) *	1981-08-17	1989-01-03	The Florida Board Of Regents On Behalf Of The Florida State University	Synthesis of derivatives of codeine and other 3-O-alkylmorphines
US5668285A (en) *	1986-10-31	1997-09-16	The United States Of America As Represented By The Department Of Health And Human Services	Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
CA2067200C (fr) *	1989-10-16	1998-06-30	Kenner C. Rice	Synthese totale d'enantiomeres de la northebaine, normorphine, noroxymorphone et de leurs derives par des intermediaires n-nor

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA913077A (en) *		1972-10-24	J. Pachter Irwin	Process of preparing n-substituted 14-hydroxydihydronormorphines
US3249616A (en) *		1966-05-03		Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof
US2772270A (en) *	1954-10-21	1956-11-27	M J Lewenstein	14-hydroxymorphinone and 8, 14-dihydroxydihydromorphinone
US2806033A (en) *	1955-08-03	1957-09-10	Lewenstein	Morphine derivative
BE638369A (fr) *	1962-10-10
US3332950A (en) *	1963-03-23	1967-07-25	Endo Lab	14-hydroxydihydronormorphinone derivatives
NL7106612A (en) *	1971-05-13	1972-11-15		N-cycloalkylalkyl-14-hydroxy-dihydronormorphines - - by o-demethylation of 14-methoxy cpds
US3775414A (en) *	1972-05-10	1973-11-27	Bristol Myers Co	Process for the preparation of 14-hydroxymorphinan derivatives
US4161597A (en) *	1976-12-20	1979-07-17	Research Corporation	N-alkyl-14-hydroxymorphinans and derivatives

1980
- 1980-07-16 NO NO802139A patent/NO802139L/no unknown
- 1980-08-07 FI FI802479A patent/FI802479A7/fi not_active Application Discontinuation
- 1980-08-07 WO PCT/US1980/000998 patent/WO1981000409A1/fr not_active Ceased
- 1980-08-07 BE BE0/201677A patent/BE884671A/fr unknown
- 1980-08-07 IT IT8068267A patent/IT8068267A0/it unknown
- 1980-08-07 GB GB8107295A patent/GB2066256A/en not_active Withdrawn
- 1980-08-07 NL NL8020319A patent/NL8020319A/nl not_active Application Discontinuation
- 1980-08-07 AU AU61165/80A patent/AU6116580A/en not_active Abandoned
- 1980-08-07 JP JP50198480A patent/JPS56501010A/ja active Pending
- 1980-08-07 IL IL60783A patent/IL60783A0/xx unknown
- 1980-08-08 ES ES494122A patent/ES494122A0/es active Granted
- 1980-08-08 FR FR8017530A patent/FR2465735A1/fr not_active Withdrawn
- 1980-08-09 PL PL22616280A patent/PL226162A1/xx unknown
- 1980-09-08 DD DD80223221A patent/DD154541A5/de unknown
1981
- 1981-04-03 DK DK151781A patent/DK151781A/da not_active Application Discontinuation
- 1981-04-07 SE SE8102214A patent/SE8102214L/xx unknown

Also Published As

Publication number	Publication date
JPS56501010A (fr)	1981-07-23
NL8020319A (nl)	1981-07-01
GB2066256A (en)	1981-07-08
BE884671A (fr)	1980-12-01
WO1981000409A1 (fr)	1981-02-19
PL226162A1 (fr)	1981-04-24
AU6116580A (en)	1981-02-12
ES494122A0 (es)	1981-04-16
FR2465735A1 (fr)	1981-03-27
IT8068267A0 (it)	1980-08-07
DD154541A5 (de)	1982-03-31
DK151781A (da)	1981-04-03
SE8102214L (sv)	1981-04-07
FI802479A7 (fi)	1981-01-01
IL60783A0 (en)	1980-10-26
NO802139L (no)	1981-02-10

Similar Documents

Publication	Publication Date	Title
IL49552A (en)	1979-05-31	Adhesive compositions
NZ194303A (en)	1982-05-31	2- phenylimidazo (4,5-b) pyridines
MX170995B (es)	1993-09-24	Procedimiento para la preparacion de n-fenilsulfonil-n'-pirimidinil y triazinil-ureas
ES391026A1 (es)	1974-04-01	Procedimiento para la obtencion de benzonaftiridina.
ES8306727A1 (es)	1983-06-01	Un procedimiento para la preparacion de fenilaminoimidazolidinas.
ES8104261A1 (es)	1981-04-16	Procedimiento para la preparacion de 2-amino-4-halogeno-5- formil-tiazoleno.
GB966222A (en)	1964-08-06	Derivatives of cephalosporin c
ES469423A1 (es)	1979-04-01	Un procedimiento para la produccion de los antibioticos antitumorales ma 144-m1 o 144-m2.
ES8705441A1 (es)	1987-05-01	Procedimiento para preparar nuevos derivados imidazo
ES477074A1 (es)	1979-06-16	Un procedimiento de preparacion de tris-(hidroximetil)-ami- nometano.
CH614932A5 (en)	1979-12-28	Process for the preparation of new terpenoaromatic amidines
ES405479A1 (es)	1975-08-16	Un procedimiento para la preparacion de derivados de benzo-diacepina.
ES398142A1 (es)	1974-08-01	Procedimiento para la preparacion de nuevos 1-feniltriaze- nos disustituidos en posicion 3.
ES434460A1 (es)	1976-12-16	Procedimiento para la preparacion de diamidas.
ES8603386A1 (es)	1985-12-16	"procedimiento para preparar 3-ciano-4-aminoacetofenonas"
ES400878A1 (es)	1975-09-01	Procedimiento para la obtencion de o-(s - triazinil-6)-2,6-dicloro - benzaldoxima.
ES413742A1 (es)	1976-01-16	Un procedimiento para la preparacion de compuestos de acidol-alfa-hidrazino-betaf-fenilpropionico.
GB2013672A (en)	1979-08-15	Process for the Production of Monorden and Derivatives Thereof
ES400859A1 (es)	1975-02-01	Procedimiento para la preparacion, por nitracion directa, de dinitrofenoles.
ES8601827A1 (es)	1985-11-16	Procedimiento para la preparacion de fenoxicicloalcanoles sustituidos.
ES8207499A1 (es)	1982-09-16	Un procedimiento para la preparacion de un catalizador reactivo.
JPS5686148A (en)	1981-07-13	Preparation of sulfobetaine
JPS55102561A (en)	1980-08-05	2-aroylformyl-substituted pyrrole derivative and its preparation
ES8400105A1 (es)	1983-01-16	"procedimiento para la preparacion de alcohiltioacilaminoacidos sustituidos".
ES396386A1 (es)	1975-01-01	Procedimiento para la obtencion de compuestos complejos 1:2de cobalto.