ES8603180A1 - Procedimiento de obtencion de la n-(2-tenoil)-n-(2-ceto-2, 3, 4, 5-tetrahidro-tiofen-3-il)-amina - Google Patents

Procedimiento de obtencion de la n-(2-tenoil)-n-(2-ceto-2, 3, 4, 5-tetrahidro-tiofen-3-il)-amina

Info

Publication number
ES8603180A1
ES8603180A1 ES530843A ES530843A ES8603180A1 ES 8603180 A1 ES8603180 A1 ES 8603180A1 ES 530843 A ES530843 A ES 530843A ES 530843 A ES530843 A ES 530843A ES 8603180 A1 ES8603180 A1 ES 8603180A1
Authority
ES
Spain
Prior art keywords
tetrahydrothiophenone
affections
respiratory system
derivative active
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530843A
Other languages
English (en)
Other versions
ES530843A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yason SRL
Original Assignee
Yason SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yason SRL filed Critical Yason SRL
Publication of ES8603180A1 publication Critical patent/ES8603180A1/es
Publication of ES530843A0 publication Critical patent/ES530843A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DEL COMPUESTO DE FORMULA (I). MEDIANTE REACCION DEL CLORHIDRATO DE HOMICSTEIN-TIOLACTONA CON UN DERIVADO DEL ACIDO 2-TIOFEN-CARBOXILICO, PREFERENTEMENTE EL CLORURO DEL ACIDO, EN PRESENCIA DE UNA BASE, PARTICULARMENTE HIDROXIDO ALCALINO, EN UN SOLVENTE ADECUADO COMO UN HIDROCARBURO AROMATICO. LA ACILACION SE EFECTUA ENTRE 0JC Y 20JC, ADICIONANDOSE EL CLORURO DE ACIDO A LA MEZCLA DE REACCION ENTRE 0JC Y 5JC. DE APLICACION PARA EL TRATAMIENTO DE AFECCIONES DEL APARATO RESPIRATORIO.
ES530843A 1983-03-23 1984-03-22 Procedimiento de obtencion de la n-(2-tenoil)-n-(2-ceto-2, 3, 4, 5-tetrahidro-tiofen-3-il)-amina Granted ES530843A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20239/83A IT1161218B (it) 1983-03-23 1983-03-23 Derivato del tetraidrotiofenone attivo nelle affezioni broncopolmonari

Publications (2)

Publication Number Publication Date
ES8603180A1 true ES8603180A1 (es) 1985-05-16
ES530843A0 ES530843A0 (es) 1985-05-16

Family

ID=11165038

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530843A Granted ES530843A0 (es) 1983-03-23 1984-03-22 Procedimiento de obtencion de la n-(2-tenoil)-n-(2-ceto-2, 3, 4, 5-tetrahidro-tiofen-3-il)-amina

Country Status (5)

Country Link
EP (1) EP0120359A1 (es)
JP (1) JPS59190989A (es)
ES (1) ES530843A0 (es)
IT (1) IT1161218B (es)
ZA (1) ZA841819B (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2265355B1 (es) * 1974-03-28 1977-11-04 Blum Jean

Also Published As

Publication number Publication date
IT8320239A0 (it) 1983-03-23
ES530843A0 (es) 1985-05-16
JPS59190989A (ja) 1984-10-29
ZA841819B (en) 1984-10-31
EP0120359A1 (en) 1984-10-03
IT1161218B (it) 1987-03-18

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