ES8705446A1 - Procedimiento para preparar derivados de imidazo 1,5-anpirimidina - Google Patents

Procedimiento para preparar derivados de imidazo 1,5-anpirimidina

Info

Publication number
ES8705446A1
ES8705446A1 ES552544A ES552544A ES8705446A1 ES 8705446 A1 ES8705446 A1 ES 8705446A1 ES 552544 A ES552544 A ES 552544A ES 552544 A ES552544 A ES 552544A ES 8705446 A1 ES8705446 A1 ES 8705446A1
Authority
ES
Spain
Prior art keywords
imidazo
preparation
pyrimidine derivatives
halogen
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552544A
Other languages
English (en)
Other versions
ES552544A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Publication of ES8705446A1 publication Critical patent/ES8705446A1/es
Publication of ES552544A0 publication Critical patent/ES552544A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE DERIVADOS DE IMIDAZO (1,5-A) PIRIDINA. CONSISTENTE EN LA OBTENCION DE COMPUESTOS DE FORMULA (I), DONDE R1 ES HALOGENO; R2 ES HIDROGENO O HALOGENO; X ES AZUFRE, SULFINILO, SULFONILO U OXIGENO; M Y N SON 0 O 1; Y A ES FENILO O HETEROCICLICO AROMATICO, OPCIONALMENTE SUSTITUIDOS, O CICLOALQUILO; MEDIANTE CONDENSACION DE COMPUESTOS N-ACILAMINOETILPIRIMIDINA DE FORMULA (II) CON HALUROS DE FOSFORO Y DE FOSFORILO Y POSTERIOR HALOGENACION, EN SU CASO, CON N-BROMOSUCCINIMIDA O N-CLOROSUCCINIMIDA. LA APLICACION EN ENFERMEDADES PROVOCADAS POR HONGOS.
ES552544A 1984-08-07 1986-02-28 Procedimiento para preparar derivados de imidazo 1,5-anpirimidina Expired ES8705446A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59165468A JPS6143191A (ja) 1984-08-07 1984-08-07 イミダゾ〔１，５−ａ〕ピリミジン誘導体

Publications (2)

Publication Number Publication Date
ES8705446A1 true ES8705446A1 (es) 1987-05-01
ES552544A0 ES552544A0 (es) 1987-05-01

Family

ID=15812984

Family Applications (2)

Application Number Title Priority Date Filing Date
ES545973A Expired ES8609327A1 (es) 1984-08-07 1985-08-07 Procedimiento para preparar derivados de imidazo (1,5-a)pi- rimidina
ES552544A Expired ES8705446A1 (es) 1984-08-07 1986-02-28 Procedimiento para preparar derivados de imidazo 1,5-anpirimidina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES545973A Expired ES8609327A1 (es) 1984-08-07 1985-08-07 Procedimiento para preparar derivados de imidazo (1,5-a)pi- rimidina

Country Status (11)

Country Link
US (1) US4914104A (es)
EP (1) EP0171739B1 (es)
JP (1) JPS6143191A (es)
KR (1) KR860001808A (es)
AT (1) ATE49411T1 (es)
AU (1) AU582377B2 (es)
CA (1) CA1244019A (es)
DE (1) DE3575305D1 (es)
DK (1) DK357285A (es)
ES (2) ES8609327A1 (es)
HU (1) HU192344B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8823041D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823042D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
IE914327A1 (en) * 1990-12-13 1992-06-17 Smithkline Beecham Corp Novel csaids
US6297198B1 (en) 1996-05-14 2001-10-02 Syngenta Participations Ag Isoxazole derivatives and their use as herbicides
CA2485148A1 (en) * 2002-05-09 2003-11-20 Cytokinetics, Inc. Pyrimidinone compounds, compositions and methods
JP2005530806A (ja) * 2002-05-23 2005-10-13 メルク　エンド　カムパニー　インコーポレーテッド 有糸分裂キネシン阻害薬
EP2075014B9 (en) 2002-05-24 2012-02-01 Angiotech International Ag Compositions and methods for coating medical implants
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
JP2007518711A (ja) * 2003-12-19 2007-07-12 メルク　エンド　カムパニー　インコーポレーテッド 有糸分裂キネシン阻害剤
WO2006088028A1 (ja) * 2005-02-15 2006-08-24 Gifu University ２－アザインドリジン類の製造方法、２－アザインドリジン類金属錯体の製造方法及び２－アザインドリジン類金属錯体
KR101394245B1 (ko) * 2005-12-30 2014-05-14 에스케이바이오팜 주식회사 아이속사졸 유도체 및 이의 용도
US10989491B2 (en) 2017-02-10 2021-04-27 Mcp Ip, Llc Archery bow with wide ratio limb

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2160020A1 (de) * 1971-12-03 1973-06-07 Bayer Ag Perchlor-imidazo-pyrimidin, verfahren zu seiner herstellung, sowie seine verwendung als fungizid
US4178449A (en) * 1978-04-17 1979-12-11 American Cyanamid Company Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
JPS6019789A (ja) * 1983-07-12 1985-01-31 Kyorin Pharmaceut Co Ltd イミダゾ〔１，５−ａ〕ピリミジン誘導体

Also Published As

Publication number Publication date
US4914104A (en) 1990-04-03
JPH0556352B2 (es) 1993-08-19
DK357285A (da) 1986-02-08
AU4561785A (en) 1986-02-13
JPS6143191A (ja) 1986-03-01
ES8609327A1 (es) 1986-07-16
HUT38643A (en) 1986-06-30
CA1244019A (en) 1988-11-01
ES545973A0 (es) 1986-07-16
DK357285D0 (da) 1985-08-06
EP0171739A1 (en) 1986-02-19
DE3575305D1 (de) 1990-02-15
ATE49411T1 (de) 1990-01-15
ES552544A0 (es) 1987-05-01
KR860001808A (ko) 1986-03-22
EP0171739B1 (en) 1990-01-10
AU582377B2 (en) 1989-03-23
HU192344B (en) 1987-05-28

Similar Documents

Publication Publication Date Title
ES8705446A1 (es) Procedimiento para preparar derivados de imidazo 1,5-anpirimidina
DE69939950D1 (de) Verwendung von neuregulin zur beeinflussung der herzmuskelfunktion
NO911600L (no) Fremgangsmaate for fremstilling av n-(3-fluor-2-fosfonyl-metoksypropyl)-derivater av heterocykliske purin- og pyrimidinbaser.
DE3789812D1 (de) Poröser wafer zur segmentierten herstellung von bipolymeren.
DK454086D0 (da) Quinolinderivater og deres anvendelse
DK0424802T3 (da) Tricykliske quinolinforbindelser med antineoplastisk aktivitet
NO850564L (no) Fremgangsmaate for fremstilling av terapeutisk aktive (2-okso-1,2,3,5-tetrahydroimidazo 2,1-b kinazolinyl) oksyalkylamider
NO874302L (no) Fremgangsmaate for fremstilling av 4,5-dihydro- og 4,5,6,7-tetrahydro- pyrazolo(1,5-a)pyrimidiner.
DE58903876D1 (de) Riboflavin-4'5'-cyclo-phosphorsaeureesterchlorid, dessen herstellung und verwendung zur herstellung von riboflavin-5'-phosphat (5'-fmn) bzw. dessen natriumsalz.
ES2032317T3 (es) Derivados de quinazolina tetraciclicos, obtencion y empleo.
DD132664A5 (de) Verfahren zur herstellung von 1,2,4-triazol-(5)-yl(thio)-phosphat
DE3365125D1 (en) Substituted benzoyl(thio) ureas, process for their preparation and their use as parasiticides
SE8700555D0 (sv) Purine derivatives, their production and medicaments containing them
ATE252106T1 (de) Verwendung von 2-(substituierte thio)thiazolo(4,5-b)pyridinverbindungen als schädlingsbekämpfungsmittel und parasitizide
ATA313780A (de) Verfahren zur herstellung von 4-(substituierten) thio-1-b-d-ribofuranosylpyrazolo(3,4-d)pyrimidinderivaten
DE3585702D1 (de) Herstellung von (trifluormethyl)pyridinen.
DK478485A (da) 4-oxo-pyrido(2,3-d)pyrimidin-derivater, deres fremstilling og anvendelse
DE3774176D1 (de) Substituierte n-phenylpyridazon-derivate.
DE3671624D1 (de) Methioninsubstituierte 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung.
DK105186D0 (da) Benzoylurinstoffer, deres fremstilling og anvendelse til bekaempelse af skadelige organismer
ATE1100T1 (de) Oxadiazolylmethylthiolphosphate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen.
DE3862840D1 (de) Verfahren zur herstellung von alkylierten dodecahydro-naphtho(2,1-b)-furanen.
ES541910A0 (es) Procedimiento para la fabricacion de derivados de 4,7-dihi- dropirazolo (3,4-b)piridina
ES2062611T3 (es) Derivados de naftol, procedimiento para su preparacion y su utilizacion.
EP0169851A4 (en) MARKER OF THE BREAST EPITHELIC CELLS.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401