FI893359L - Fr 901228-foerening och foerfarande foer dess framstaellning. - Google Patents

Fr 901228-foerening och foerfarande foer dess framstaellning. Download PDF

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Publication number
FI893359L
FI893359L FI893359A FI893359A FI893359L FI 893359 L FI893359 L FI 893359L FI 893359 A FI893359 A FI 893359A FI 893359 A FI893359 A FI 893359A FI 893359 L FI893359 L FI 893359L
Authority
FI
Finland
Prior art keywords
foerening
foerfarande foer
och foerfarande
foer dess
dess framstaellning
Prior art date
Application number
FI893359A
Other languages
English (en)
Finnish (fi)
Other versions
FI893359A0 (fi
FI893359A7 (fi
Inventor
Masakuni Okuhara
Toshio Goto
Yasuhiro Hori
Takashi Fujita
Hirotsugu Ueda
Nobuharu Shigematsu
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10641100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI893359(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI893359A0 publication Critical patent/FI893359A0/fi
Publication of FI893359L publication Critical patent/FI893359L/fi
Publication of FI893359A7 publication Critical patent/FI893359A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Reinforced Plastic Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
FI893359A 1988-07-26 1989-07-11 FR 901228-yhdiste ja menetelmä sen valmistamiseksi FI893359A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888817743A GB8817743D0 (en) 1988-07-26 1988-07-26 Fr901228 substance & preparation thereof

Publications (3)

Publication Number Publication Date
FI893359A0 FI893359A0 (fi) 1989-07-11
FI893359L true FI893359L (fi) 1990-01-27
FI893359A7 FI893359A7 (fi) 1990-01-27

Family

ID=10641100

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893359A FI893359A7 (fi) 1988-07-26 1989-07-11 FR 901228-yhdiste ja menetelmä sen valmistamiseksi

Country Status (16)

Country Link
US (1) US4977138A (de)
EP (1) EP0352646B1 (de)
JP (1) JPH0764872B2 (de)
CN (1) CN1040054A (de)
AT (1) ATE94561T1 (de)
AU (1) AU3829089A (de)
CA (1) CA1335083C (de)
DE (1) DE68909139T2 (de)
DK (1) DK366889A (de)
ES (1) ES2058411T3 (de)
FI (1) FI893359A7 (de)
GB (1) GB8817743D0 (de)
HU (1) HU211514A9 (de)
IL (1) IL90949A0 (de)
NO (1) NO893021L (de)
ZA (1) ZA895121B (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130414A (en) * 1989-11-30 1992-07-14 Arizona Board Of Regents, A Body Corporate Of Arizona State University Isolation and structural elucidation of the cyclic peptide hymenistatin 1
JPH06247964A (ja) * 1993-02-22 1994-09-06 Snow Brand Milk Prod Co Ltd 新規生理活性物質ｈｓ−１及びその製造方法
TR199901118T2 (xx) * 1996-11-22 1999-07-21 Pioneer Hi-Bred International, Inc. Moniliformin detoksifikasyon bile�imleri ve y�ntemleri .
KR100611265B1 (ko) 1999-01-13 2006-08-10 아스텔라스세이야쿠 가부시키가이샤 신규 뎁시펩티드 화합물
EP1779859B1 (de) * 1999-12-08 2010-06-09 Cyclacel Pharmaceuticals, Inc. Depsipetid und Kongenere davon für den Einsatz als Immunsuppressiva zur Vorbeugung und Behandlung von Abstossreaktionen infolge einer Transplantation und zur Induktion des Apoptosis in aktivierten CD4 oder CD8 T-Zellen
US6828302B1 (en) 1999-12-08 2004-12-07 Xcyte Therapies, Inc. Therapeutic uses of depsipeptides and congeners thereof
ATE425177T1 (de) * 2000-07-17 2009-03-15 Astellas Pharma Inc Reduziertes fk228 und seine verwendung
US7396665B2 (en) * 2000-09-01 2008-07-08 Astellas Pharma, Inc. Method of producing FR901228
HU229521B1 (hu) * 2001-08-21 2014-01-28 Astellas Pharma Inc A hiszton-dezacetiláz inhibitor gyógyászati alkalmazása, és eljárás tumorellenes hatásának kiértékelésére
US20040132643A1 (en) * 2002-01-09 2004-07-08 Fojo Antonio Tito Histone deacelylase inhibitors in diagnosis and treatment of thyroid neoplasms
MXPA04009761A (es) * 2002-04-05 2005-05-27 Fujisawa Pharmaceutical Co Dipsipeptido para terapia de cancer renal.
US20080233562A1 (en) * 2003-02-19 2008-09-25 Astellas Pharma Inc. Method of Estimating Antitumor Effect of Histone Deacetylase Inhibitor
DK2238982T3 (da) * 2003-06-27 2013-01-28 Astellas Pharma Inc Terapeutisk middel til blødt væv-sarcom
PL1670514T3 (pl) * 2003-09-25 2010-11-30 Astellas Pharma Inc Środek przeciwnowotworowy zawierający inhibitor deacetylazy histonowej i inhibitor topoizomerazy II
WO2005058298A2 (en) * 2003-12-10 2005-06-30 Wisconsin Alumni Research Foundation Fk228 analogs and their use as hdac-inhibitors
US20050187148A1 (en) * 2004-02-25 2005-08-25 Yoshinori Naoe Antitumor agent
US7951780B2 (en) * 2004-02-25 2011-05-31 Astellas Pharma Inc. Antitumor agent
US20050261174A1 (en) * 2004-05-20 2005-11-24 Paul Lewer Insecticidal activity of a cyclic peptide
EP1812036A2 (de) * 2004-11-17 2007-08-01 The University Of Chicago Histon-deacetylase-hemmer und anwendungsverfahren
GB0511266D0 (en) * 2005-06-02 2005-07-13 Trust Chemical compounds
EP1965824A4 (de) * 2005-11-18 2011-10-19 Gloucester Pharmaceuticals Inc Metaboliten-derivate des hdac-inhibitors fk228
WO2007145704A2 (en) * 2006-04-24 2007-12-21 Gloucester Pharmaceuticals Gemcitabine combination therapy
US8957027B2 (en) 2006-06-08 2015-02-17 Celgene Corporation Deacetylase inhibitor therapy
WO2008083288A2 (en) * 2006-12-29 2008-07-10 Gloucester Pharmaceuticals Purifiction of romidepsin
EP2450049A1 (de) 2006-12-29 2012-05-09 Gloucester Pharmaceuticals, Inc. Tumorbehandlung auf der basis von romidepsin
WO2008098199A2 (en) * 2007-02-08 2008-08-14 Uwm Research Foundation, Inc. Sequences for fk228 biosyntnesis and methods of synthesizing fk228 and fk228 analogs
US20110060021A1 (en) * 2009-08-19 2011-03-10 Yiqiang Cheng Histone deacetylase inhibitors and uses thereof
AR080234A1 (es) * 2010-02-25 2012-03-21 Marrone Bio Innovations Inc Cepa bacteriana aislada del genero burkholderia y metabolitos pesticidas del mismo
SG10201505475XA (en) 2010-07-12 2015-09-29 Celgene Corp Romidepsin solid forms and uses thereof
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
IN2014MN00242A (de) * 2011-08-27 2015-09-25 Marrone Bio Innovations Inc
CA2849708A1 (en) 2011-09-23 2013-03-28 Celgene Corporation Romidepsin and 5 - azacitidine for use in treating lymphoma
US20130244950A1 (en) 2011-09-26 2013-09-19 Celgene Corporation Combination therapy for chemoresistant cancers
JP6214397B2 (ja) 2011-09-30 2017-10-18 国立大学法人東北大学 新規ホスファチジルイノシトール３キナーゼ阻害剤及び医薬組成物
WO2013085902A1 (en) 2011-12-05 2013-06-13 The University Of Texas M.D. Combination therapy methods for treating an inflammatory breast cancer
EP2802340B1 (de) * 2012-01-12 2020-10-28 Celgene Corporation Romidepsinformulierungen und ihre verwendungen
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
CN103877010B (zh) * 2012-12-21 2018-06-01 正大天晴药业集团股份有限公司 一种罗米地辛溶液的制备方法
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
EP3473615B1 (de) 2013-02-28 2022-01-19 Journey Medical Corporation Glycopyrrolat-salze
CN103173390B (zh) * 2013-03-16 2014-09-10 浙江海正药业股份有限公司 一种紫色杆菌菌株及其应用
CN104072589B (zh) * 2013-03-29 2017-09-22 浙江海正药业股份有限公司 抗肿瘤三硫化合物及其制备方法与应用
CN104450837B (zh) * 2013-09-18 2019-01-01 上海医药工业研究院 一种用于生产罗米地辛的方法及发酵培养基
CN104447950A (zh) * 2013-09-18 2015-03-25 上海医药工业研究院 一种罗米地辛的分离纯化方法
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
US10294276B2 (en) * 2014-03-04 2019-05-21 Concord Biotech Limited Process for isolation of romidepsin from fermentation broth and preparation of crystals of romidepsin
CN104894195B (zh) * 2014-03-07 2018-11-13 上海医药工业研究院 一种提高fk228产量的发酵培养基
CN104262456B (zh) * 2014-09-11 2018-01-09 浙江海正药业股份有限公司 一种罗米地辛的新晶型及其制备方法和用途
US10669528B2 (en) 2015-06-25 2020-06-02 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance
WO2017068596A1 (en) * 2015-10-20 2017-04-27 Msn Laboratories Private Limited An improved process for the preparation of (1s, 4s, 7z, 10s, 16e, 21r)- 7-ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5, 8, 20, 23- tetraazabicyclo[8.7.6]tricos-16-ene-3, 6, 9, 19, 22-pentone
WO2017161001A1 (en) 2016-03-15 2017-09-21 Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion
US20220015372A1 (en) 2018-12-14 2022-01-20 Pioneer Hi-Bred International, Inc. Biologicals and their use in plants
WO2020139453A2 (en) * 2018-12-24 2020-07-02 Marrone Bio Innovations, Inc. A method for increasing romidepsin production from fermentation broth

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986006065A1 (en) * 1985-04-18 1986-10-23 Pfizer Inc. Transformation product of thiosporamicin
EP0253245B1 (de) * 1986-07-08 1992-10-14 Takeda Chemical Industries, Ltd. Biologisch aktive Peptide TAN-866
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics

Also Published As

Publication number Publication date
DE68909139T2 (de) 1994-02-10
ES2058411T3 (es) 1994-11-01
NO893021D0 (no) 1989-07-25
CN1040054A (zh) 1990-02-28
IL90949A0 (en) 1990-02-09
ZA895121B (en) 1990-08-29
JPH0285296A (ja) 1990-03-26
DK366889D0 (da) 1989-07-25
JPH0764872B2 (ja) 1995-07-12
EP0352646A2 (de) 1990-01-31
GB8817743D0 (en) 1988-09-01
DK366889A (da) 1990-01-27
FI893359A0 (fi) 1989-07-11
NO893021L (no) 1990-01-29
CA1335083C (en) 1995-04-04
FI893359A7 (fi) 1990-01-27
HU211514A9 (en) 1995-11-28
US4977138A (en) 1990-12-11
EP0352646B1 (de) 1993-09-15
ATE94561T1 (de) 1993-10-15
AU3829089A (en) 1990-02-01
EP0352646A3 (en) 1990-10-31
DE68909139D1 (de) 1993-10-21

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: FUJISAWA PHARMACEUTICAL CO., LTD.