FR2242093A1 - 5-Amino-4-formylcarbamoyl-pyrazoles - prepd. by cyclization of N-formyl-2-cyano-3-(N'-acyl-hydrazino)-acrylamides - Google Patents
5-Amino-4-formylcarbamoyl-pyrazoles - prepd. by cyclization of N-formyl-2-cyano-3-(N'-acyl-hydrazino)-acrylamidesInfo
- Publication number
- FR2242093A1 FR2242093A1 FR7429083A FR7429083A FR2242093A1 FR 2242093 A1 FR2242093 A1 FR 2242093A1 FR 7429083 A FR7429083 A FR 7429083A FR 7429083 A FR7429083 A FR 7429083A FR 2242093 A1 FR2242093 A1 FR 2242093A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- amino
- substd
- methylene
- replaced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- NTQWMNGZJUFFGB-UHFFFAOYSA-N 5-amino-N-formyl-1H-pyrazole-4-carboxamide Chemical class NC=1NN=CC=1C(=O)NC=O NTQWMNGZJUFFGB-UHFFFAOYSA-N 0.000 title 1
- 238000007363 ring formation reaction Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- RIDQSQFLDYDOAC-UHFFFAOYSA-N 5-amino-N-formyl-1-propanoylpyrazole-4-carboxamide Chemical compound C(CC)(=O)N1N=CC(=C1N)C(NC=O)=O RIDQSQFLDYDOAC-UHFFFAOYSA-N 0.000 abstract 1
- 206010052895 Coronary artery insufficiency Diseases 0.000 abstract 1
- 201000005569 Gout Diseases 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 abstract 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 abstract 1
- 108010093894 Xanthine oxidase Proteins 0.000 abstract 1
- 102100033220 Xanthine oxidase Human genes 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003217 pyrazoles Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 229940116269 uric acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU68318A LU68318A1 (fr) | 1973-08-27 | 1973-08-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2242093A1 true FR2242093A1 (en) | 1975-03-28 |
Family
ID=19727454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7429083A Withdrawn FR2242093A1 (en) | 1973-08-27 | 1974-08-26 | 5-Amino-4-formylcarbamoyl-pyrazoles - prepd. by cyclization of N-formyl-2-cyano-3-(N'-acyl-hydrazino)-acrylamides |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE819196A (fr) |
| DE (1) | DE2440777A1 (fr) |
| FR (1) | FR2242093A1 (fr) |
| LU (1) | LU68318A1 (fr) |
-
1973
- 1973-08-27 LU LU68318A patent/LU68318A1/xx unknown
-
1974
- 1974-08-26 DE DE19742440777 patent/DE2440777A1/de active Pending
- 1974-08-26 FR FR7429083A patent/FR2242093A1/fr not_active Withdrawn
- 1974-08-26 BE BE147915A patent/BE819196A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2440777A1 (de) | 1975-03-06 |
| LU68318A1 (fr) | 1975-05-21 |
| BE819196A (fr) | 1975-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |