FR2346007A1 - Nouvelles compositions anti-inflammatoires administrables per os - Google Patents

Nouvelles compositions anti-inflammatoires administrables per os

Info

Publication number: FR2346007A1
Authority: FR; France
Prior art keywords: resistant coating; proteolytic enzymes; oxyphenbutazone; gastro; butazone
Prior art date: 1976-03-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

FR7609044A

Other languages

English (en)

Other versions

FR2346007B1 (fr

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CREAT

Original Assignee

CREAT

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-03-29

Filing date

1976-03-29

Publication date

1977-10-28

1976-03-29 Application filed by CREAT filed Critical CREAT

1976-03-29 Priority to FR7609044A priority Critical patent/FR2346007A1/fr

1977-10-28 Publication of FR2346007A1 publication Critical patent/FR2346007A1/fr

1979-05-18 Application granted granted Critical

1979-05-18 Publication of FR2346007B1 publication Critical patent/FR2346007B1/fr

Status Granted legal-status Critical Current

Links

239000011248 coating agent Substances 0.000 title abstract 4
238000000576 coating method Methods 0.000 title abstract 4
102000035195 Peptidases Human genes 0.000 title abstract 3
108091005804 Peptidases Proteins 0.000 title abstract 3
230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 title abstract 2
239000002260 anti-inflammatory agent Substances 0.000 title 1
229940121363 anti-inflammatory agent Drugs 0.000 title 1
229960002895 phenylbutazone Drugs 0.000 title 1
VYMDGNCVAMGZFE-UHFFFAOYSA-N phenylbutazonum Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 VYMDGNCVAMGZFE-UHFFFAOYSA-N 0.000 title 1
HFHZKZSRXITVMK-UHFFFAOYSA-N oxyphenbutazone Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=C(O)C=C1 HFHZKZSRXITVMK-UHFFFAOYSA-N 0.000 abstract 3
229960000649 oxyphenbutazone Drugs 0.000 abstract 3
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 2
239000001913 cellulose Substances 0.000 abstract 2
229920002678 cellulose Polymers 0.000 abstract 2
239000008101 lactose Substances 0.000 abstract 2
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
239000000454 talc Substances 0.000 abstract 2
229910052623 talc Inorganic materials 0.000 abstract 2
229920000084 Gum arabic Polymers 0.000 abstract 1
108010067035 Pancrelipase Proteins 0.000 abstract 1
241000978776 Senegalia senegal Species 0.000 abstract 1
229920002472 Starch Polymers 0.000 abstract 1
239000000205 acacia gum Substances 0.000 abstract 1
235000010489 acacia gum Nutrition 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
230000009849 deactivation Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002496 gastric effect Effects 0.000 abstract 1
239000011777 magnesium Substances 0.000 abstract 1
235000019359 magnesium stearate Nutrition 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 1
210000000496 pancreas Anatomy 0.000 abstract 1
239000008107 starch Substances 0.000 abstract 1
235000019698 starch Nutrition 0.000 abstract 1
238000005303 weighing Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FR7609044A 1976-03-29 1976-03-29 Nouvelles compositions anti-inflammatoires administrables per os Granted FR2346007A1 (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
FR7609044A FR2346007A1 (fr)	1976-03-29	1976-03-29	Nouvelles compositions anti-inflammatoires administrables per os

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7609044A FR2346007A1 (fr)	1976-03-29	1976-03-29	Nouvelles compositions anti-inflammatoires administrables per os

Publications (2)

Publication Number	Publication Date
FR2346007A1 true FR2346007A1 (fr)	1977-10-28
FR2346007B1 FR2346007B1 (fr)	1979-05-18

Family

ID=9171071

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7609044A Granted FR2346007A1 (fr)	1976-03-29	1976-03-29	Nouvelles compositions anti-inflammatoires administrables per os

Country Status (1)

Country	Link
FR (1)	FR2346007A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0135022A3 (fr) *	1983-07-27	1986-11-26	Beecham Group Plc	Composition contenant un allergène
EP0196002A3 (en) *	1985-03-25	1987-12-02	Abbott Laboratories	Tablet composition for drug combinations

1976
- 1976-03-29 FR FR7609044A patent/FR2346007A1/fr active Granted

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0135022A3 (fr) *	1983-07-27	1986-11-26	Beecham Group Plc	Composition contenant un allergène
EP0196002A3 (en) *	1985-03-25	1987-12-02	Abbott Laboratories	Tablet composition for drug combinations

Also Published As

Publication number	Publication date
FR2346007B1 (fr)	1979-05-18

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Legal Events

Date	Code	Title
1978-09-29	TP	Transmission of property
1981-02-20	CA	Change of address
1981-02-20	CD	Change of name or company name
1981-02-20	TP	Transmission of property
1983-12-09	TP	Transmission of property
1987-01-23	ST	Notification of lapse