FR2408839A1 - Procede et appareil pour mesurer la lumiere diffusee par du plasma sanguin afin de determiner le temps de coagulation de ce sang - Google Patents

Procede et appareil pour mesurer la lumiere diffusee par du plasma sanguin afin de determiner le temps de coagulation de ce sang

Info

Publication number
FR2408839A1
FR2408839A1 FR7831872A FR7831872A FR2408839A1 FR 2408839 A1 FR2408839 A1 FR 2408839A1 FR 7831872 A FR7831872 A FR 7831872A FR 7831872 A FR7831872 A FR 7831872A FR 2408839 A1 FR2408839 A1 FR 2408839A1
Authority
FR
France
Prior art keywords
blood
light diffused
blood plasma
coagulation time
time
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7831872A
Other languages
English (en)
Other versions
FR2408839B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arkray Inc
Original Assignee
Kyoto Daiichi Kagaku KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Daiichi Kagaku KK filed Critical Kyoto Daiichi Kagaku KK
Publication of FR2408839A1 publication Critical patent/FR2408839A1/fr
Application granted granted Critical
Publication of FR2408839B1 publication Critical patent/FR2408839B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Ecology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

PROCEDE ET APPAREIL POUR MESURER LA LUMIERE DIFFUSEE PAR DU PLASMA SANGUIN, POUR CONNAITRE LE TEMPS DE COAGULATION DE CE SANG. UN MELANGE DE PLASMA SANGUIN ET DE REACTIF EST IRRADIE PAR UNE QUANTITE SPECIFIEE DE LUMIERE; LES VARIATIONS DE LA LUMIERE DIFFUSEE PAR CE MELANGE SONT DECELEES, TRANSFORMEES EN SIGNAUX NUMERIQUES A DES INTERVALLES SPECIFIES DE TEMPS ET ENVOYEES DANS UNE CALCULATRICE CALCULANT LA DIFFERENCE ENTRE CHAQUE VALEUR D'ENTREE ET LA VALEUR IMMEDIATEMENT VOISINE DANS LE TEMPS ET CONSERVANT LES RESULTATS EN MEMOIRE. LA CALCULATRICE DETERMINE L'INSTANT D'UNE DIFFERENCE MAXIMALE ET L'INSTANT PRECEDENT OU LA DIFFERENCE VALAIT 1N DE LA DIFFERENCE MAXIMALE, CE QU'INDIQUE LE TEMPS DE COAGULATION. APPLICATION: DETERMINATION PRECISE ET RAPIDE, OU MESURE EN SERIE, POUR UN DIAGNOSTIC OU AVANT UNE OPERATION CHIRURGICALE.
FR7831872A 1977-11-12 1978-11-10 Procede et appareil pour mesurer la lumiere diffusee par du plasma sanguin afin de determiner le temps de coagulation de ce sang Granted FR2408839A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13595677A JPS5469497A (en) 1977-11-12 1977-11-12 Method and device for measuring blood solidification time

Publications (2)

Publication Number Publication Date
FR2408839A1 true FR2408839A1 (fr) 1979-06-08
FR2408839B1 FR2408839B1 (fr) 1983-12-09

Family

ID=15163762

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7831872A Granted FR2408839A1 (fr) 1977-11-12 1978-11-10 Procede et appareil pour mesurer la lumiere diffusee par du plasma sanguin afin de determiner le temps de coagulation de ce sang

Country Status (4)

Country Link
US (1) US4252536A (fr)
JP (1) JPS5469497A (fr)
DE (1) DE2848552C2 (fr)
FR (1) FR2408839A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2476312A1 (fr) * 1980-02-16 1981-08-21 Compur Electronic Gmbh Procede de photometrie et appareil photometrique permettant de determiner le deroulement de reactions
FR2571497A1 (fr) * 1984-10-09 1986-04-11 Toa Medical Electronics Cy Ltd Appareil a mesurer le temps de coagulation du sang
EP0184242A3 (en) * 1984-11-27 1987-10-07 Instrumentation Laboratory S.P.A. Instrument for measuring coagulation parameters and method of use
EP0178910A3 (en) * 1984-10-15 1988-11-17 Ortho Diagnostic Systems Inc. Methods for coagulation monitoring

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352557A (en) * 1979-10-20 1982-10-05 Ernst Leitz Wetzlar Gmbh Determining a test value corresponding to blood subsidence
JPS56137140A (en) * 1980-03-27 1981-10-26 Wako Pure Chem Ind Ltd Optical measuring method of blood coagulation
JPS58109837A (ja) * 1981-12-24 1983-06-30 Olympus Optical Co Ltd 検量線補正方法
US4766083A (en) * 1982-04-04 1988-08-23 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
US4605618A (en) * 1983-07-11 1986-08-12 New York University Method for measuring anti-inflammatory properties of a composition
JPS6058555A (ja) * 1983-09-09 1985-04-04 Toa Medical Electronics Co Ltd 血液凝固測定方法および測定装置
US4597944A (en) * 1983-10-18 1986-07-01 Cottingham Hugh V Agglutination reagent detection system
US5114860A (en) * 1984-10-09 1992-05-19 Toa Medical Electronics Co., Ltd. Device of measuring a blood coagulating time
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
JP2610434B2 (ja) * 1987-06-05 1997-05-14 株式会社 京都第一科学 血液凝固能測定方法
US5197017A (en) * 1990-09-27 1993-03-23 Carroll Wallace E Potentiophotometric fibrinogen determination
DK203191D0 (da) * 1991-12-19 1991-12-19 Novo Nordisk As Fremgangsmaade og apparat til bestemmelse af relevante blodparametre
US5526111A (en) * 1993-08-31 1996-06-11 Boehringer Mannheim Corporation Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control
US5522255A (en) * 1993-08-31 1996-06-04 Boehringer Mannheim Corporation Fluid dose, flow and coagulation sensor for medical instrument
US5502651A (en) * 1994-05-02 1996-03-26 Jackson; R. David Potentiophotometric fibrinogen determination
WO1998039643A1 (fr) * 1997-03-05 1998-09-11 Diametrics Procede et appareil de mesure des parametres de coagulation du sang total
US7126676B2 (en) * 2002-11-07 2006-10-24 Frank Anthony Greco Spectral analysis of light scattered from clotting blood
US7276377B2 (en) * 2003-05-02 2007-10-02 Wada, Inc. Method and apparatus for determining anticoagulant therapy factors
US20040219680A1 (en) * 2003-05-02 2004-11-04 Carroll Wallace E. Method and apparatus for determining anticoagulant therapy factors
ES2665788T3 (es) * 2004-07-27 2018-04-27 Lsi Medience Corporation Procedimiento de determinación automática de una muestra
JP5164388B2 (ja) * 2007-01-31 2013-03-21 シスメックス株式会社 試料測定装置
DE102007017906A1 (de) * 2007-04-17 2008-10-23 Dade Behring Marburg Gmbh Verfahren zur Bestimmung der Reaktions-Lag-Phase in einer analytabhängigen Reaktion
US8445287B2 (en) * 2009-02-14 2013-05-21 Wada, Inc. Method and apparatus for determining anticoagulant therapy factors
FR2943789B1 (fr) 2009-03-26 2013-07-26 Commissariat Energie Atomique Procede et dispositif pour la caracterisation de la dynamique de coagulation ou sedimentation d'un fluide tel que le sang ou le plasma sanguin
CN102640004B (zh) * 2009-12-04 2015-04-15 株式会社日立高新技术 血液凝固分析装置
JP5608871B2 (ja) * 2010-03-09 2014-10-15 学校法人慶應義塾 レーザカテーテル出射部の血液焦げ付き防止システム
GB201014316D0 (en) 2010-08-27 2010-10-13 Univ Dublin City A agglutination assay method and device
US8697449B2 (en) * 2011-04-01 2014-04-15 Spectral Sciences, Inc. Optical blood coagulation monitor and method
DE102011001952B8 (de) * 2011-04-11 2012-12-20 Johann-Wolfgang-Goethe Universität Frankfurt am Main Vorrichtung und Verfahren zur Bestimmung der Koagulationszeit von Blut
JP6035329B2 (ja) * 2011-05-26 2016-11-30 ザ ジェネラル ホスピタル コーポレイション 光学的トロンボエラストグラフィーシステム及び血液凝固基準の評価方法
WO2014100378A1 (fr) 2012-12-19 2014-06-26 The General Hospital Corporation Capteur optique de coagulation sanguine
JP5889480B2 (ja) * 2013-04-02 2016-03-22 株式会社日立ハイテクノロジーズ 自動分析装置及び分析方法
US9970948B2 (en) 2013-11-26 2018-05-15 Hitachi High-Technologies Corporation Automatic analyzer
JP6563681B2 (ja) * 2015-05-08 2019-08-21 シスメックス株式会社 検体分析装置、血液凝固分析装置、検体分析方法、及びコンピュータプログラム
EP4134675A4 (fr) * 2020-04-07 2024-01-17 Sekisui Medical Co., Ltd. Procédé de mesure du temps de coagulation du sang
CN112161955B (zh) * 2020-07-22 2024-11-12 三诺生物传感股份有限公司 一种用于凝血四项的测试方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3307392A (en) * 1964-05-04 1967-03-07 Research Corp Automatic prothrombin timer apparatus and method
CH446768A (fr) * 1965-04-29 1967-11-15 Medical Laboratory Automation Procédé de détermination du temps correspondant au point de coagulation dans des tests de coagulation du sang
FR2364453A1 (fr) * 1976-09-08 1978-04-07 Lacombe Pierre Dispositif electronique apportant un perfectionnement aux appareils destines a analyser la coagulation sanguine : prothrombinometre citrate-oxalate
FR2404853A1 (fr) * 1977-09-30 1979-04-27 Sankyo Co Procede et dispositif de detection du temps de coagulation du sang

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3450501A (en) * 1966-03-28 1969-06-17 Bruce J Oberhardt Prothrombin time determination
US3463614A (en) * 1966-11-29 1969-08-26 Cutler Hammer Inc Method and apparatus for use in promoting agglomeration
US3498135A (en) * 1968-11-13 1970-03-03 Baxter Laboratories Inc Pipette
US3593568A (en) * 1969-04-01 1971-07-20 Bio Dynamics Inc Prothrombin time measuring apparatus with means to start the timer in response to the initial decrement of optical transmissivity
GB1545538A (en) * 1975-11-17 1979-05-10 Gradient Pty Ltd Method and apparatus for simultaneously recording reaction times

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3307392A (en) * 1964-05-04 1967-03-07 Research Corp Automatic prothrombin timer apparatus and method
CH446768A (fr) * 1965-04-29 1967-11-15 Medical Laboratory Automation Procédé de détermination du temps correspondant au point de coagulation dans des tests de coagulation du sang
FR2364453A1 (fr) * 1976-09-08 1978-04-07 Lacombe Pierre Dispositif electronique apportant un perfectionnement aux appareils destines a analyser la coagulation sanguine : prothrombinometre citrate-oxalate
FR2404853A1 (fr) * 1977-09-30 1979-04-27 Sankyo Co Procede et dispositif de detection du temps de coagulation du sang

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2476312A1 (fr) * 1980-02-16 1981-08-21 Compur Electronic Gmbh Procede de photometrie et appareil photometrique permettant de determiner le deroulement de reactions
FR2571497A1 (fr) * 1984-10-09 1986-04-11 Toa Medical Electronics Cy Ltd Appareil a mesurer le temps de coagulation du sang
EP0178910A3 (en) * 1984-10-15 1988-11-17 Ortho Diagnostic Systems Inc. Methods for coagulation monitoring
EP0184242A3 (en) * 1984-11-27 1987-10-07 Instrumentation Laboratory S.P.A. Instrument for measuring coagulation parameters and method of use

Also Published As

Publication number Publication date
JPS6110777B2 (fr) 1986-03-31
DE2848552A1 (de) 1979-05-17
JPS5469497A (en) 1979-06-04
FR2408839B1 (fr) 1983-12-09
DE2848552C2 (de) 1982-03-25
US4252536A (en) 1981-02-24

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