GR1003591B - Μεσον για την αυξηση της απελευθερωσης ακετυλχολινης στον εγκεφαλο. - Google Patents

Μεσον για την αυξηση της απελευθερωσης ακετυλχολινης στον εγκεφαλο.

Info

Publication number
GR1003591B
GR1003591B GR20000100145A GR2000100145A GR1003591B GR 1003591 B GR1003591 B GR 1003591B GR 20000100145 A GR20000100145 A GR 20000100145A GR 2000100145 A GR2000100145 A GR 2000100145A GR 1003591 B GR1003591 B GR 1003591B
Authority
GR
Greece
Prior art keywords
anisoyl
acetylcholic
enhances
brain
release
Prior art date
Application number
GR20000100145A
Other languages
English (en)
Other versions
GR20000100145A (el
Inventor
Kazuo Nakamura
Yushiro Tanaka
Masatoshi Shirane
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of GR20000100145A publication Critical patent/GR20000100145A/el
Publication of GR1003591B publication Critical patent/GR1003591B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται στην χρήση Ν-ανισοϋλ-γ-αμινο-βουτυρικού οξέος (Ν-ανισοϋλ-GABA) ή π-ανισικού οξέος για την παρασκευή μίας φαρμακευτικής σύνθεσης που αυξάνει την απελευθέρωση ακετυλχολίνης (ACh) στον εγκέφαλο. Ειδικότερα, η εφεύρεση αναφέρεται στην χρήση Ν-ανισοϋλ-GABA ή π-ανισικού οξέος για την θεραπευτική αγωγή διαταραχών του κιρκάνιου ρυθμού, διαταραχών του ύπνου, διαταραχών με έλλειψη προσοχής και προβληματικών συμπεριφορών. Η εφεύρεση αναφέρεται επίσης σε φαρμακευτικές συνθέσεις που περιέχουν Ν-ανισοϋλ-GABA ή π-ανισικό οξύ ως αποτελεσματικό συστατικό.ΰ
GR20000100145A 1999-04-27 2000-04-24 Μεσον για την αυξηση της απελευθερωσης ακετυλχολινης στον εγκεφαλο. GR1003591B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99108223 1999-04-27

Publications (2)

Publication Number Publication Date
GR20000100145A GR20000100145A (el) 2000-12-29
GR1003591B true GR1003591B (el) 2001-05-22

Family

ID=8238054

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000100145A GR1003591B (el) 1999-04-27 2000-04-24 Μεσον για την αυξηση της απελευθερωσης ακετυλχολινης στον εγκεφαλο.

Country Status (24)

Country Link
US (1) US20030073744A1 (el)
JP (1) JP2000309529A (el)
KR (1) KR100372906B1 (el)
CN (1) CN1277019A (el)
AR (1) AR023763A1 (el)
AT (1) AT408836B (el)
AU (1) AU3011300A (el)
BE (1) BE1013314A3 (el)
BR (1) BR0002381A (el)
CA (1) CA2307022A1 (el)
DE (1) DE10020237A1 (el)
DK (1) DK200000687A (el)
ES (1) ES2176078A1 (el)
FI (1) FI20000977A7 (el)
FR (1) FR2792833B1 (el)
GB (1) GB2351662A (el)
GR (1) GR1003591B (el)
IE (1) IE20000308A1 (el)
IT (1) IT1318490B1 (el)
NL (1) NL1015043C2 (el)
PT (1) PT102456B (el)
SE (1) SE0001499L (el)
TR (1) TR200001133A2 (el)
ZA (1) ZA200002041B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5273731B2 (ja) * 2009-08-11 2013-08-28 独立行政法人産業技術総合研究所 生体リズムの制御剤
KR20210090688A (ko) * 2018-11-13 2021-07-20 시엔펑 펑 아미노산의 아실화 유도체가 동물 사료 첨가제의 제조에 있어서의 응용

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
JPH1081626A (ja) * 1996-09-06 1998-03-31 Kamiyama:Kk チロシナーゼ活性阻害剤
JPH1081607A (ja) * 1996-09-06 1998-03-31 Kamiyama:Kk 抗菌剤

Also Published As

Publication number Publication date
FR2792833A1 (fr) 2000-11-03
TR200001133A2 (tr) 2000-11-21
KR100372906B1 (ko) 2003-02-17
PT102456B (pt) 2003-04-30
GB2351662A (en) 2001-01-10
BR0002381A (pt) 2000-11-07
FI20000977L (fi) 2000-10-27
ITMI20000914A0 (it) 2000-04-21
CA2307022A1 (en) 2000-10-27
AU3011300A (en) 2000-11-02
KR20010029658A (ko) 2001-04-06
ES2176078A1 (es) 2002-11-16
IT1318490B1 (it) 2003-08-25
AT408836B (de) 2002-03-25
DK200000687A (da) 2000-10-28
NL1015043C2 (nl) 2001-03-30
PT102456A (pt) 2000-11-30
AR023763A1 (es) 2002-09-04
FR2792833B1 (fr) 2002-09-06
GB0010049D0 (en) 2000-06-14
SE0001499L (sv) 2000-10-28
IE20000308A1 (en) 2000-11-29
US20030073744A1 (en) 2003-04-17
GR20000100145A (el) 2000-12-29
FI20000977A0 (fi) 2000-04-26
JP2000309529A (ja) 2000-11-07
ITMI20000914A1 (it) 2001-10-21
DE10020237A1 (de) 2001-02-08
FI20000977A7 (fi) 2000-10-27
NL1015043A1 (nl) 2000-10-30
BE1013314A3 (fr) 2001-11-06
ATA7162000A (de) 2001-08-15
SE0001499D0 (sv) 2000-04-26
ZA200002041B (en) 2000-10-27
CN1277019A (zh) 2000-12-20

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GR1003591B (el) Μεσον για την αυξηση της απελευθερωσης ακετυλχολινης στον εγκεφαλο.
AU2002224847A1 (en) N-alkylated gaba compounds, processes for their preparation and their use as medicaments