GR850473B - - Google Patents

Info

Publication number
GR850473B
GR850473B GR850473A GR850100473A GR850473B GR 850473 B GR850473 B GR 850473B GR 850473 A GR850473 A GR 850473A GR 850100473 A GR850100473 A GR 850100473A GR 850473 B GR850473 B GR 850473B
Authority
GR
Greece
Prior art keywords
pyridazinone
imidazolyl
hypertension
dihydro
methyl
Prior art date
Application number
GR850473A
Other languages
English (en)
Inventor
Jurgen Dr Biedermann
Harald Dr Borbe
Erich Dr Graf
Gerd Dr Hilboll
Gerrit Dr Prop
Original Assignee
Nattermann 8 Cie Gmbh A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann 8 Cie Gmbh A filed Critical Nattermann 8 Cie Gmbh A
Publication of GR850473B publication Critical patent/GR850473B/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR850473A 1984-03-01 1985-02-22 GR850473B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843407509 DE3407509A1 (de) 1984-03-01 1984-03-01 Neue arzneimittelkombination zur behandlung von bluthochdruck und thromboembolischen erkrankungen

Publications (1)

Publication Number Publication Date
GR850473B true GR850473B (el) 1985-05-31

Family

ID=6229261

Family Applications (1)

Application Number Title Priority Date Filing Date
GR850473A GR850473B (el) 1984-03-01 1985-02-22

Country Status (8)

Country Link
US (2) US4661487A (el)
EP (1) EP0156163B1 (el)
JP (1) JPS60202819A (el)
AT (1) ATE38470T1 (el)
DE (2) DE3407509A1 (el)
DK (1) DK93485A (el)
GR (1) GR850473B (el)
ZA (1) ZA851548B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3535170A1 (de) * 1985-10-02 1987-04-16 Basf Ag Verwendung von 2-aryl-3,4-diaza-bicyclo(4.n.0)alken-(2)-onen-(5) zur behandlung der herzinsuffizienz
DE3805635A1 (de) * 1988-02-24 1989-09-07 Thomae Gmbh Dr K Verwendung von benzimidazolen zur herstellung eines arzneimittels mit antiischaemischen wirkungen am herzen und dessen kombinationen mit ss-blockern oder bradycardica
EP0375247B1 (en) * 1988-12-21 1996-02-28 Texas Instruments Incorporated Metastable tolerant latch
US20110015246A2 (en) * 2005-03-14 2011-01-20 Agean Llc Lofexidine enantiomers for use as a treatment for cns disease and pathologies and its chiral synthesis
US20090246256A1 (en) * 2008-03-27 2009-10-01 Al-Ghananeem Abeer M Compositions and Methods for Transmucosal Delivery of Lofexidine
WO2010075275A1 (en) * 2008-12-23 2010-07-01 Usworldmeds Llc Selective release of non-racemic mixtures of two enantiomers from tablets and capsules

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795843U (de) 1959-06-12 1959-09-17 Johannes Schlueter Chem Fab Bohnergeraet mit vorratsbehaelter und einrichtung zur portionsweisen abgabe von fluessigwachs.
HU190412B (en) * 1981-09-17 1986-09-29 Warner-Lambert Co,Us Process for producing substituted 4,5-dihiydro-6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones and 6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones
DE3149009A1 (de) 1981-12-10 1983-06-23 A. Nattermann & Cie GmbH, 5000 Köln (-)-2-(1-(2,6-dichlorphenoxy)-ethyl)-1,3-diazacyclopent-2-en, dessen herstellung und seine verwendung in pharmazeutischen praeparaten
DE3212304A1 (de) * 1982-04-02 1983-10-06 Nattermann A & Cie Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3241102A1 (de) * 1982-11-06 1984-05-10 A. Nattermann & Cie GmbH, 5000 Köln Imidazolylalkylthienyl-tetrahydropyridazine und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPS60202819A (ja) 1985-10-14
DK93485D0 (da) 1985-02-28
US4661487A (en) 1987-04-28
EP0156163A1 (en) 1985-10-02
US4746660A (en) 1988-05-24
ZA851548B (en) 1985-10-30
DK93485A (da) 1985-09-02
DE3566079D1 (en) 1988-12-15
DE3407509A1 (de) 1985-09-05
ATE38470T1 (de) 1988-11-15
EP0156163B1 (en) 1988-11-09

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