HUT57790A - Process for producing deoxyfluoronucleoside derivatives - Google Patents

Process for producing deoxyfluoronucleoside derivatives

Info

Publication number: HUT57790A
Authority: HU; Hungary
Prior art keywords: deoxyfluoronucleoside; derivatives; producing; producing deoxyfluoronucleoside; deoxyfluoronucleoside derivatives
Prior art date: 1989-11-13

Application number

HU907113A

Other languages

English (en)

Other versions

HU208149B (en

HU907113D0 (en

Inventor

Purushotham Vemishetti

Henry G Howell

Paul R Brodfuehrer

Kun Mao Shih

Donald G Walker

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-13

Filing date

1990-11-13

Publication date

1991-12-30

1990-11-13 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1991-05-28 Publication of HU907113D0 publication Critical patent/HU907113D0/hu

1991-12-30 Publication of HUT57790A publication Critical patent/HUT57790A/hu

1993-08-30 Publication of HU208149B publication Critical patent/HU208149B/hu

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HU907113A 1989-11-13 1990-11-13 Process for producing deoxyfluoronucleoside derivatives HU208149B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US43585289A	1989-11-13	1989-11-13

Publications (3)

Publication Number	Publication Date
HU907113D0 HU907113D0 (en)	1991-05-28
HUT57790A true HUT57790A (en)	1991-12-30
HU208149B HU208149B (en)	1993-08-30

Family

ID=23730082

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
HU906976A HU906976D0 (en)	1989-11-13	1990-11-01	Process for producing 2', 3'-didesoxy-2'-fluoarabinonucleoside analogues
HU9303049A HU9303049D0 (en)	1989-11-13	1990-11-13	6-substituted 9-(9-dezoxy-2-fluor-beta-d-arabino-furanozyl)-purines and method for producing them
HU907113A HU208149B (en)	1989-11-13	1990-11-13	Process for producing deoxyfluoronucleoside derivatives
HU9303048A HU9303048D0 (en)	1989-11-13	1990-11-13	9-(2-desoxy-5-0-benzoyl-2-fluor-beta-d-arabino-furanozyl)-6-chlor-purine and method for producing it

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
HU906976A HU906976D0 (en)	1989-11-13	1990-11-01	Process for producing 2', 3'-didesoxy-2'-fluoarabinonucleoside analogues
HU9303049A HU9303049D0 (en)	1989-11-13	1990-11-13	6-substituted 9-(9-dezoxy-2-fluor-beta-d-arabino-furanozyl)-purines and method for producing them

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
HU9303048A HU9303048D0 (en)	1989-11-13	1990-11-13	9-(2-desoxy-5-0-benzoyl-2-fluor-beta-d-arabino-furanozyl)-6-chlor-purine and method for producing it

Country Status (12)

Country	Link
EP (1)	EP0428109A3 (hu)
JP (1)	JPH03170496A (hu)
KR (1)	KR910009717A (hu)
AU (1)	AU6596590A (hu)
CA (1)	CA2029301A1 (hu)
FI (1)	FI905536A7 (hu)
HU (4)	HU906976D0 (hu)
IE (1)	IE904070A1 (hu)
IL (1)	IL96306A0 (hu)
NO (1)	NO174206C (hu)
PT (1)	PT95861A (hu)
ZA (1)	ZA909042B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5606048A (en) *	1992-06-22	1997-02-25	Eli Lilly And Company	Stereoselective glycosylation process for preparing 2'-Deoxy-2', 2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5821357A (en) *	1992-06-22	1998-10-13	Eli Lilly And Company	Stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoropurine and triazole nucleosides
SG94686A1 (en) *	1992-06-22	2003-03-18	Lilly Co Eli	Stereoselective gylcosylation process
AU659009B2 (en) *	1992-06-22	1995-05-04	Eli Lilly And Company	Stereoselective glycosylation process
ES2101231T3 (es) *	1992-06-22	1997-07-01	Lilly Co Eli	Procedimiento estereoselectivo de glicosilacion de anion.
US5426183A (en) *	1992-06-22	1995-06-20	Eli Lilly And Company	Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5401838A (en) *	1992-06-22	1995-03-28	Eli Lilly And Company	Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
AU659008B2 (en) *	1992-06-22	1995-05-04	Eli Lilly And Company	Stereoselective anion glycosylation process
US5594124A (en) *	1992-06-22	1997-01-14	Eli Lilly And Company	Stereoselective glycosylation process for preparing 2'-Deoxy-2',2'-difluoropyrimidine nucleosides and 2'-deoxy-2'-fluoropyrimidine nucleosides and intermediates thereof
UA41261C2 (uk) *	1992-06-22	2001-09-17	Елі Ліллі Енд Компані	Спосіб одержання збагачених бета-аномером нуклеозидів
US5371210A (en) *	1992-06-22	1994-12-06	Eli Lilly And Company	Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5424416A (en) *	1993-08-25	1995-06-13	Eli Lilly And Company	Process for preparation of 2-deoxy-2,2-difluoro-D-ribofuranosyl-3,5-hydroxy protected-1-alkyl and aryl sulfonates and their use in preparation of 2',2'-difluoro-2'-deoxy nucleosides
AT400953B (de) *	1994-08-25	1996-05-28	Joern Saischek	Pentofuranosid-derivate, deren herstellung und verwendung
JPH11217396A (ja) *	1998-01-30	1999-08-10	Ajinomoto Co Inc	ヌクレオシド誘導体の製造方法
JP4555536B2 (ja) *	2000-02-18	2010-10-06	サザン・リサーチ・インスティテュート	２−クロロ−９−（２−デオキシ−２−フルオロ−β−Ｄ−アラビノフラノシル）−９Ｈ−プリン−６−アミンの合成方法
ES2306783T3 (es)	2001-08-02	2008-11-16	Ilex Oncology, Inc.	Procedimiento para preparar nucleosidos purinicos.
PT2710019T (pt)	2011-05-19	2017-07-21	Gilead Sciences Inc	Processos e intermediários para preparar agentes anti-hiv
EP3661937B1 (en)	2017-08-01	2021-07-28	Gilead Sciences, Inc.	Crystalline forms of ethyl ((s)-((((2r,5r)-5-(6-amino-9h-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninate (gs-9131) for treating viral infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4751221A (en) *	1985-10-18	1988-06-14	Sloan-Kettering Institute For Cancer Research	2-fluoro-arabinofuranosyl purine nucleosides
CA1340645C (en) *	1987-04-17	1999-07-13	Victor E. Marquez	Acid stable dideoxynucleosides active against the cytopathic effects of human immunodeficiency virus
NZ226672A (en) *	1987-10-30	1991-07-26	Hoffmann La Roche	6-amino-9-(2,3-dideoxy-2-fluoro-b-d-threopentofuranosyl)-9h-purine derivatives and pharmaceutical compositions
GB8816345D0 (en) *	1988-07-08	1988-08-10	Hoffmann La Roche	Purine derivatives

1990
- 1990-11-01 HU HU906976A patent/HU906976D0/hu unknown
- 1990-11-05 CA CA002029301A patent/CA2029301A1/en not_active Abandoned
- 1990-11-08 FI FI905536A patent/FI905536A7/fi not_active IP Right Cessation
- 1990-11-09 NO NO904870A patent/NO174206C/no unknown
- 1990-11-12 PT PT95861A patent/PT95861A/pt not_active Application Discontinuation
- 1990-11-12 EP EP19900121636 patent/EP0428109A3/en not_active Withdrawn
- 1990-11-12 IE IE407090A patent/IE904070A1/en unknown
- 1990-11-12 KR KR1019900018266A patent/KR910009717A/ko not_active Withdrawn
- 1990-11-12 AU AU65965/90A patent/AU6596590A/en not_active Abandoned
- 1990-11-12 ZA ZA909042A patent/ZA909042B/xx unknown
- 1990-11-12 IL IL96306A patent/IL96306A0/xx unknown
- 1990-11-13 HU HU9303049A patent/HU9303049D0/hu unknown
- 1990-11-13 JP JP2304179A patent/JPH03170496A/ja active Pending
- 1990-11-13 HU HU907113A patent/HU208149B/hu not_active IP Right Cessation
- 1990-11-13 HU HU9303048A patent/HU9303048D0/hu unknown

Also Published As

Publication number	Publication date
NO904870L (no)	1991-05-14
FI905536A0 (fi)	1990-11-08
KR910009717A (ko)	1991-06-28
EP0428109A2 (en)	1991-05-22
IL96306A0 (en)	1991-08-16
EP0428109A3 (en)	1991-09-11
NO174206C (no)	1994-04-06
PT95861A (pt)	1991-09-13
HU906976D0 (en)	1991-05-28
AU6596590A (en)	1991-05-16
CA2029301A1 (en)	1991-05-14
HU208149B (en)	1993-08-30
HU907113D0 (en)	1991-05-28
JPH03170496A (ja)	1991-07-24
HU9303048D0 (en)	1994-01-28
FI905536A7 (fi)	1991-05-14
IE904070A1 (en)	1991-05-22
ZA909042B (en)	1991-09-25
NO904870D0 (no)	1990-11-09
NO174206B (no)	1993-12-20
HU9303049D0 (en)	1994-01-28

Legal Events

Date	Code	Title	Description
1995-08-28	HMM4	Cancellation of final prot. due to non-payment of fee

Publication	Publication Date	Title
HU902462D0 (en)	1990-08-28	Process for producing 3-substituted-2-oxindole derivatives
HUT50783A (en)	1990-03-28	Process for producing new isoquinolinon derivatives
HU902106D0 (en)	1990-07-28	Process for producing cephodisime-disodium
ZA909042B (en)	1991-09-25	Deoxfluoronucleoside process
HU903908D0 (en)	1990-11-28	Process for producing new r(-)-3-quinuclidinole derivatives
HU904920D0 (en)	1991-01-28	Process for producing neoalkyl-triol-triesthers
HU906464D0 (en)	1991-04-29	Process for producing chloro-fluoro-propanes
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HUT53884A (en)	1990-12-28	Process for producing 1-aryl-sulfonyl-pirrolidine-2-thion- and 1-arylsulfonyl-piperidine-2-thion derivatives
HUT52513A (en)	1990-07-28	Process for producing cepheme derivatives
HUT53092A (en)	1990-09-28	Process for producing new benzazol derivatives
HU907067D0 (en)	1991-05-28	Process for producing sphingenine derivatives
HUT57212A (en)	1991-11-28	Process for producing tetrahydroo-triazolo-tetrazepine derivatives